Liquid lung ventilation reduces neutrophil sequestration in a neonatal swine model of cardiopulmonary bypass.

abstract：BACKGROUND:Prevalence and causes of sex-based differences in morbidity and mortality secondary to cardiovascular disease remain controversial. Cardiac troponin I (cTnI) is a sensitive and specific marker for myocardial injury. Serial cTnI measurements have been used to identify perioperative myocardial cell injury. OB...

journal_title：Critical care medicine

authors： Schwarzenberger JC,Sun LS,Pesce MA,Heyer EJ,Delphin E,Almeida GM,Wood M

更新日期：2003-03-01 00:00:00

abstract：INTRODUCTION:The difficult airway is a common problem in adult critical care patients. However, the challenge is not just the establishment of a safe airway, but also maintaining that safety over days, weeks, or longer. AIMS:This review considers the management of the difficult airway in the adult critical care enviro...

journal_title：Critical care medicine

authors： Lavery GG,McCloskey BV

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVES:Hospitals use a variety of strategies to maximize the availability of limited ICU beds. Boarding, which involves assigning patients to an open bed in a different subspecialty ICU, is one such practice employed when ICU occupancy levels are high, and beds in a particular unit are unavailable. Boarding disrupt...

journal_title：Critical care medicine

authors： Stretch R,Della Penna N,Celi LA,Landon BE

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Conventional outcomes research provides only percentage risk of such end points as mortality rate, utilization of resources, and/or broad groupings of multiple organ system dysfunction. These prognostications generally are not applicable to individual patients. The purpose of the present study was to determin...

journal_title：Critical care medicine

authors： Slotman GJ

更新日期：2002-05-01 00:00:00

abstract：:The aim of this study was to assess prospectively the variations of serum phosphorus concentration (P) after onset of mechanical ventilation (MV) in patients with chronic obstructive pulmonary disease (COPD) and acute respiratory acidosis. In 14 COPD patients, we measured P, PaCO2, and pH, immediately before MV (H0), ...

journal_title：Critical care medicine

authors： Laaban JP,Grateau G,Psychoyos I,Laromiguière M,Vuong TK,Rochemaure J

更新日期：1989-11-01 00:00:00

abstract：OBJECTIVE:Because anemia of inflammation is common in ICU patients and hepcidin is the key regulator of iron homeostasis, we examined time-dependent changes in hepcidin, erythropoietin, iron, and inflammatory markers in surgical ICU patients with anemia. DESIGN:Prospective single-center clinical noninterventional stud...

journal_title：Critical care medicine

authors： Cherry-Bukowiec JR,Engoren M,Wiktor A,Raghavendran K,Napolitano LM

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:Effective therapies are needed to reverse the increased vascular permeability that characterizes acute inflammatory diseases such as acute lung injury. FTY720 is a pharmaceutical analog of the potent barrier-enhancing phospholipid, sphingosine 1-phosphate. Because both FTY720 and sphingosine 1-phosphate have ...

journal_title：Critical care medicine

authors： Wang L,Sammani S,Moreno-Vinasco L,Letsiou E,Wang T,Camp SM,Bittman R,Garcia JG,Dudek SM

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:To describe a case of hepatic subcapsular hematoma causing an acute Budd-Chiari-like syndrome, leading to hepatic compartment syndrome, which combines compression of intrahepatic vessels on CT, acute liver failure, and refractory shock. DESIGN:Case report. SETTING:Surgical ICU of a university teaching hospi...

journal_title：Critical care medicine

authors： Marcaire F,Malavieille F,Pichot-Delahaye V,Floccard B,Rimmelé T

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:To determine xanthine oxidase activity, free radical concentrations, and lipid peroxidation in patients with sepsis syndrome compared with noninfected critically ill patients. DESIGN:A prospective observational study. SETTING:A nine-bed intensive care unit in a university teaching hospital trust. PATIENTS:...

journal_title：Critical care medicine

authors： Galley HF,Davies MJ,Webster NR

更新日期：1996-10-01 00:00:00

abstract：:Among Gram-positive pathogens, Staphylococcus aureus is the leading cause of death from nosocomial pneumonia. The bacterium developed progressive resistance to beta-lactams, and methicillin-resistant strains emerged in the 1980s. In consequence, vancomycin has become the drug of choice for treatment of this infection ...

journal_title：Critical care medicine

authors： Bodi M,Ardanuy C,Rello J

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:Acute lung injury secondary to smoke inhalation is a major source of morbidity and mortality in burn patients. We tested the hypothesis that nebulized epinephrine would ameliorate pulmonary dysfunction secondary to acute lung injury by reducing airway hyperemia and edema formation and mediating bronchodilatat...

journal_title：Critical care medicine

authors： Lange M,Hamahata A,Traber DL,Cox RA,Kulp GA,Nakano Y,Traber LD,Herndon DN,Enkhbaatar P

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:Cytomegalovirus reactivation may complicate critical illness in latent carriers of the virus, even in patients who were previously immunocompetent. Patients with acute respiratory distress syndrome are considered to be prone for reactivation. Prophylactic antiviral therapy in immunocompetent cytomegalovirus s...

journal_title：Critical care medicine

authors： Ong DS,Klein Klouwenberg PM,Verduyn Lunel FM,Spitoni C,Frencken JF,Dekker HA,Schultz MJ,Bonten MJ,Cremer OL

更新日期：2015-02-01 00:00:00

abstract：:Laboratory evaluation and use of the Engström metabolic computer (EMC) in a clinical setting are described. The accuracy of the EMC was tested using an inert gas dilution technique. Mean errors in oxygen consumption (VO2) and CO2 production compared with predicted values were less than 2% of predicted, and generally l...

journal_title：Critical care medicine

authors： Regan CJ,Snowdon SL,Campbell IT

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVES:In critically ill patients, treatment dose or intensity is often related to severity of illness and mortality risk, whereas overtreatment or undertreatment (relative to the individual need) may further increase the odds of death. We aimed to investigate how these relationships affect the results of common st...

journal_title：Critical care medicine

authors： de Grooth HJ,Girbes ARJ,van der Ven F,Oudemans-van Straaten HM,Tuinman PR,de Man AME

更新日期：2020-12-01 00:00:00

abstract：:Chest physiotherapy (CPT) is used frequently in the ICU, but there is little available information that quantitates its effect on cardiac or respiratory function. Nineteen mechanically ventilated patients with post-traumatic respiratory failure were studied before, immediately after, and 2 h after CPT was used to mana...

journal_title：Critical care medicine

authors： Mackenzie CF,Shin B

更新日期：1985-06-01 00:00:00

abstract：OBJECTIVE:To examine the hypothesis that heat stress applied after the administration of bacterial endotoxin is protective. DESIGN:Prospective, randomized, laboratory study. SETTING:University research laboratory. SUBJECTS:One hundred eleven adult male Sprague-Dawley rats (weight range 250 to 400 g). INTERVENTIONS:...

journal_title：Critical care medicine

authors： Chu EK,Ribeiro SP,Slutsky AS

更新日期：1997-10-01 00:00:00

abstract：OBJECTIVE:Fibrotic changes are initiated early in acute respiratory distress syndrome. This may involve overproliferation of alveolar type II cells. In an animal model of acute respiratory distress syndrome, we have shown that the administration of an adenoviral vector overexpressing the 70-kd heat shock protein (AdHSP...

journal_title：Critical care medicine

authors： Bromberg Z,Raj N,Goloubinoff P,Deutschman CS,Weiss YG

更新日期：2008-01-01 00:00:00

abstract：:The metabolic support of critically ill patients is a relatively new topic of active research and discussion, and surprisingly little is known about the effects of critical illness on metabolic physiology and activity. The metabolic changes seen in critical illness are highly complex, and how and when to treat them ar...

journal_title：Critical care medicine

authors： Vincent JL

更新日期：2007-09-01 00:00:00

abstract：CONTEXT:Reducing aspiration of gastric contents by placing mechanically ventilated patients in a semirecumbent position has been associated with lower incidences of ventilator-associated pneumonia (VAP). The feasibility and efficacy of this intervention in a larger patient population, however, are unknown. OBJECTIVE:A...

journal_title：Critical care medicine

authors： van Nieuwenhoven CA,Vandenbroucke-Grauls C,van Tiel FH,Joore HC,van Schijndel RJ,van der Tweel I,Ramsay G,Bonten MJ

更新日期：2006-02-01 00:00:00

abstract：:Capnography is a valuable tool in the management of cardiac arrest, since end-tidal CO2 (PetCO2) correlates well with cardiac output and there are no other suitable noninvasive ways to measure this important variable during resuscitation. Animal studies also suggest that PetCO2 correlates well with the likelihood of r...

journal_title：Critical care medicine

authors： Callaham M,Barton C

更新日期：1990-04-01 00:00:00

abstract：:Several variables may account for the response of electrochemical skin surface PO2 sensors to anesthetic gases: cathode material and size, pH of the electrolyte and membrane material. These variables cannot be chosen arbitrarily and their influence has been tested with two types of sensors. In one type (LSC), a large ...

journal_title：Critical care medicine

authors： Eberhard P,Mindt W

更新日期：1981-10-01 00:00:00

abstract：OBJECTIVES:To determine plasma aluminum concentrations and 24-hr urine aluminum excretion rate in long-term mechanically ventilated patients treated with 6 g of sucralfate daily for stress ulcer prophylaxis. DESIGN:Prospective study in long-term mechanically ventilated critically ill patients. SETTING:A surgical inte...

journal_title：Critical care medicine

authors： Tryba M,Kurz-Müller K,Donner B

更新日期：1994-11-01 00:00:00

abstract：OBJECTIVE:To determine whether low-dose dopamine administration reduces the incidence or severity of acute renal failure, need for dialysis, or mortality in patients with critical illness. DATA SOURCES AND STUDY SELECTION:We performed a MEDLINE search of literature published from 1966 to 2000 for studies addressing th...

journal_title：Critical care medicine

authors： Kellum JA,M Decker J

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVES:A cuffed tracheostomy tube facilitates prolonged mechanical ventilation and weaning but usually leads to prolonged voicelessness, which can be one of the most negative experiences of hospitalization. No randomized trials have examined the effects of targeted early communication intervention for the restorati...

journal_title：Critical care medicine

authors： Freeman-Sanderson AL,Togher L,Elkins MR,Phipps PR

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:To determine whether the supplementation of parenteral nutrition with ω-3 fatty acids confers treatment benefits to critically ill adult patients. DATA SOURCE:We performed computerized searches for relevant articles from 1996 to June 2011 on MEDLINE, EMBASE, and the Cochrane register of controlled trials and...

journal_title：Critical care medicine

authors： Palmer AJ,Ho CK,Ajibola O,Avenell A

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:Head-to-head comparison of the success rate of jejunal placement of a new electromagnetically visualized jejunal tube with that of the endoscopic technique in critically ill patients. DESIGN:: Prospective, randomized clinical trial. SETTING:Two intensive care units at a university hospital. PATIENTS:: A to...

journal_title：Critical care medicine

authors： Holzinger U,Brunner R,Miehsler W,Herkner H,Kitzberger R,Fuhrmann V,Metnitz PG,Kamolz LP,Madl C

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:To determine nuclear factor kappa B (NF-kappa B) activation in mononuclear and neutrophils from critically ill patients and to compare NF-kappa B activation with circulating concentrations of interleukin (IL)-6, IL-8, and soluble intercellular adhesion molecule (sICAM)-1. DESIGN:Observational study. SETTIN...

journal_title：Critical care medicine

authors： Paterson RL,Galley HF,Dhillon JK,Webster NR

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVES:Maintenance of mean arterial pressure>65 mm Hg has been associated with improved clinical outcomes in many studies of critically ill patients. Current guidelines for the management of septic shock and guidelines for managing other critical illnesses suggest intra-arterial blood pressure measurement is prefer...

journal_title：Critical care medicine

authors： Chatterjee A,DePriest K,Blair R,Bowton D,Chin R

更新日期：2010-12-01 00:00:00

abstract：:offstudied hemodynamic and renal effects of increasing the dosage of dopamine (DP) by 5 micrograms/kg X min, in 7 patients with peritonitis and clinical findings of septic shock, all of whom were already receiving variable dosages of DP. Stroke index (SI) (p less than .01), except in 3 cases, and mean arterial pressur...

journal_title：Critical care medicine

authors： de la Cal MA,Miravalles E,Pascual T,Esteban A,Ruiz-Santana S

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:Sepsis remains a major health threat in intensive care medicine. The renin-angiotensin system (ACE) affects inflammatory responses. In addition, angiotensin-converting enzyme inhibitors act to ameliorate lung injury. To investigate whether the widely used ACE inhibitor enalapril, used to treat hypertension, c...

journal_title：Critical care medicine

authors： Hagiwara S,Iwasaka H,Matumoto S,Hidaka S,Noguchi T

更新日期：2009-02-01 00:00:00