Intravenous insulin nomogram improves blood glucose control in the critically ill.

abstract：OBJECTIVES:To investigate attitudes and practices regarding oxygen therapy in intensive care units (ICUs) and to devise quantitative descriptive indices. SETTING:Canadian university-affiliated adult ICUs. PARTICIPANTS:Fifty-two medical directors of ICUs in 48 institutions. INTERVENTION:Structured postal questionnair...

journal_title：Critical care medicine

authors： Mao C,Wong DT,Slutsky AS,Kavanagh BP

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVES:We investigated whether preexisting kidney function determines if ICU patients may benefit from increased (2.0 g/kg/d) protein intake. DESIGN:Post hoc, hypothesis-generating, subgroup analysis of a multicenter, phase 2, randomized clinical trial. All analyses were conducted by intention to treat and maintai...

journal_title：Critical care medicine

authors： Zhu R,Allingstrup MJ,Perner A,Doig GS,Nephro-Protective Trial Investigators Group.

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:Procalcitonin has been advocated as a specific biomarker for bacterial infection. We performed this study to determine whether accuracy of procalcitonin for diagnosis of postoperative bacterial infection is affected by renal function after aortic surgery. DESIGN:Single-center prospective study. SETTING:Univ...

journal_title：Critical care medicine

authors： Amour J,Birenbaum A,Langeron O,Le Manach Y,Bertrand M,Coriat P,Riou B,Bernard M,Hausfater P

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:To assess the number of adult critical care beds in Asian countries and regions in relation to population size. DESIGN:Cross-sectional observational study. SETTING:Twenty-three Asian countries and regions, covering 92.1% of the continent's population. PARTICIPANTS:Ten low-income and lower-middle-income eco...

journal_title：Critical care medicine

authors： Phua J,Faruq MO,Kulkarni AP,Redjeki IS,Detleuxay K,Mendsaikhan N,Sann KK,Shrestha BR,Hashmi M,Palo JEM,Haniffa R,Wang C,Hashemian SMR,Konkayev A,Mat Nor MB,Patjanasoontorn B,Nafees KMK,Ling L,Nishimura M,Al Bahrani

更新日期：2020-05-01 00:00:00

abstract：:The disadvantages of external ventricular drainage are the threat of sepsis and the nuisance of dislodging a precarious system in routine care. The experience of the authors with nearly 200 cases using a long ventricular catheter demonstrates that a subgaleal tunnel can be easily made for the ventricular catheter usin...

journal_title：Critical care medicine

authors： Saunders RL,Lyons TA

更新日期：1979-12-01 00:00:00

abstract：OBJECTIVE:To derive a target range of optimal sedation for the COMFORT Scale and to prospectively test that target range against intensivist assessment of adequacy of sedation. DESIGN:Serial prospective agreement cohort studies. SETTING:Twelve-bed pediatric intensive care unit in an urban academic teaching hospital. ...

journal_title：Critical care medicine

authors： Marx CM,Smith PG,Lowrie LH,Hamlett KW,Ambuel B,Yamashita TS,Blumer JL

更新日期：1994-01-01 00:00:00

abstract：:Over a 2-year period, 14 viable ventilator-dependent patients were transferred from the Medical Intensive Care Unit (MICU) to a general ward floor for nutritional support after failing to wean from mechanical ventilation (MV) while in the MICU. These patients were retrospectively grouped based on their ultimate abilit...

journal_title：Critical care medicine

authors： Larca L,Greenbaum DM

更新日期：1982-05-01 00:00:00

abstract：OBJECTIVE:Exposure of neutrophils to low doses of bacterial lipopolysaccharides enhances their readiness to respond with inflammatory mediator generation including oxygen radical formation to a subsequently applied inflammatory stimulus ("priming"). In the present study, we investigated the role of lipid mediator synth...

journal_title：Critical care medicine

authors： Sibelius U,Hattar K,Hoffmann S,Mayer K,Grandel U,Schenkel A,Seeger W,Grimminger F

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:Acute renal tubular injury is a serious complication in the postoperative period, which is associated with high mortality and increased ICU stay. We aimed to demonstrate the protective effect of rhEPO against acute tubular injury induced by ischemia-reperfusion and to explore the mechanism of canonical transi...

journal_title：Critical care medicine

authors： Shen S,Jin Y,Li W,Liu X,Zhang T,Xia W,Wang Y,Ma K

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVES:To evaluate the epidemiology of hyperammonemia unrelated to liver failure in the critical care setting. DESIGN:Retrospective case series. SETTING:Critically ill patients admitted to ICUs at Mayo Clinic, Rochester, MN (medical ICU, two mixed medical-surgical ICUs, coronary care unit, or the cardiosurgical I...

journal_title：Critical care medicine

authors： Sakusic A,Sabov M,McCambridge AJ,Rabinstein AA,Singh TD,Mukesh K,Kashani KB,Cook D,Gajic O

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:To describe blood conservation strategies for critically ill patients. DATA SOURCES:By using a predefined strategy, we searched the electronic databases of Medline, EMBASE, CINAHL, the Cochrane database of systematic reviews, Cochrane central register of controlled trials, ACP Journal Club, Database of abstr...

journal_title：Critical care medicine

authors： Fowler RA,Berenson M

更新日期：2003-12-01 00:00:00

abstract：:Little is known about the structure and objectives of various hospital ethics committees due to their need to preserve confidentiality, their reluctance to reveal internal hospital problems, and their concern about becoming involved in the developing debate about the appropriate role and value of such committees. The ...

journal_title：Critical care medicine

authors： Cohen CB

更新日期：1982-11-01 00:00:00

abstract：OBJECTIVES:Existing handheld glucose meters are glucose oxidase (GO)-based. Oxygen side reactions can introduce oxygen dependency, increase potential error, and limit clinical use. Our primary objectives were to: a) introduce a new glucose dehydrogenase (GD)-based electrochemical biosensor for point-of-care testing; b)...

journal_title：Critical care medicine

authors： Kost GJ,Vu HT,Lee JH,Bourgeois P,Kiechle FL,Martin C,Miller SS,Okorodudu AO,Podczasy JJ,Webster R,Whitlow KJ

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:To review current knowledge about cell-free hemoglobin solutions. DATA SOURCES:All studies involving cell-free hemoglobin were retrieved from a computerized MEDLINE search from 1980 to 1998. We also reviewed the reference lists of all available review articles and primary studies to identify references not f...

journal_title：Critical care medicine

authors： Creteur J,Sibbald W,Vincent JL

更新日期：2000-08-01 00:00:00

abstract：:Conventional wisdom suggests that the "human factor" in critical care environments is reason for inadequate medication and patient safety. "Human factors" (or human factors engineering) is also a scientific discipline and practice of improving human performance. Using decades of human factors research, this paper eval...

journal_title：Critical care medicine

authors： Scanlon MC,Karsh BT

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To explore the feedback regulation of glucocorticoids on corticotropin secretion in patients with septic and nonseptic circulatory shock. DESIGN:Prospective study. SETTING:An intensive care unit of a general hospital. PATIENTS:Two groups of patients with septic shock (n = 11) or nonseptic shock (n = 7). A ...

journal_title：Critical care medicine

authors： Perrot D,Bonneton A,Dechaud H,Motin J,Pugeat M

更新日期：1993-03-01 00:00:00

abstract：OBJECTIVE:In rodent models, enhanced formation of nitric oxide and formation of peroxynitrite have been implicated in the pathogenesis of various forms of shock. Here we examined the effect of mercaptoethylguanidine (MEG), an inducible nitric oxide synthase inhibitor and peroxynitrite scavenger, in a severe hemorrhagic...

journal_title：Critical care medicine

authors： Szabó A,Hake P,Salzman AL,Szabó C

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:To study the impact of diabetes mellitus on the relationship between glycemia and mortality in critically ill patients. DESIGN:Retrospective observational study. SETTING:Intensive care units of two university hospitals. PATIENTS:Cohort of 4946 critically ill patients including 728 patients with diabetes me...

journal_title：Critical care medicine

authors： Egi M,Bellomo R,Stachowski E,French CJ,Hart GK,Hegarty C,Bailey M

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:To review current knowledge about the impact of prolonged mechanical ventilation on diaphragmatic function and biology. MEASUREMENTS:Systematic literature review. CONCLUSIONS:Prolonged mechanical ventilation can promote diaphragmatic atrophy and contractile dysfunction. As few as 18 hrs of mechanical ventil...

journal_title：Critical care medicine

authors： Powers SK,Kavazis AN,Levine S

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:We tested whether mild hypothermia impacts on circulatory and respiratory dysfunction during experimental endotoxemia. DESIGN:Randomized controlled prospective experimental study. SETTING:Large animal facility, Medical University of Graz, Austria. SUBJECTS:Thirteen anesthetized and mechanically ventilated ...

journal_title：Critical care medicine

authors： Schwarzl M,Seiler S,Wallner M,von Lewinski D,Huber S,Maechler H,Steendijk P,Zelzer S,Truschnig-Wilders M,Obermayer-Pietsch B,Lueger A,Pieske BM,Post H

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVES:Hospitals use a variety of strategies to maximize the availability of limited ICU beds. Boarding, which involves assigning patients to an open bed in a different subspecialty ICU, is one such practice employed when ICU occupancy levels are high, and beds in a particular unit are unavailable. Boarding disrupt...

journal_title：Critical care medicine

authors： Stretch R,Della Penna N,Celi LA,Landon BE

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:To examine the ways in which healthcare professionals work together in the ICU setting, through a consideration of the contextual, organizational, processual, and relational factors that impact their interprofessional collaboration. DESIGN:Data from over 350 hours of ethnographic observation and 35 semistruc...

journal_title：Critical care medicine

authors： Alexanian JA,Kitto S,Rak KJ,Reeves S

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:To report two cases of severe reactive hemophagocytic syndrome (RHS), to discuss their impact, and to present evidence that RHS may be a constitutive part of multiple organ dysfunction syndrome (MODS). DESIGN:Case-report. SETTING:Pediatric intensive care unit (PICU). PATIENTS:Two patients with RHS and MODS...

journal_title：Critical care medicine

authors： Gauvin F,Toledano B,Champagne J,Lacroix J

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVES:To assess the feasibility, biochemical efficacy, and safety of liberal versus conventional glucose control in ICU patients with diabetes. DESIGN:Prospective, open-label, sequential period study. SETTING:A 22-bed mixed ICU of a tertiary hospital in Australia. PATIENTS:We compared 350 consecutive patients w...

journal_title：Critical care medicine

authors： Luethi N,Cioccari L,Biesenbach P,Lucchetta L,Kagaya H,Morgan R,Di Muzio F,Presello B,Gaafar D,Hay A,Crisman M,Toohey R,Russell H,Glassford NJ,Eastwood GM,Ekinci EI,Deane AM,Bellomo R,Mårtensson J

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:Reviews of patient safety efforts suggest that technical/administrative change must be augmented by global factors such as organizational culture and climate. The objective was to outline a comprehensive model for healthcare climate and test one of its elements, the nursing subclimate, in terms of several pa...

journal_title：Critical care medicine

authors： Zohar D,Livne Y,Tenne-Gazit O,Admi H,Donchin Y

更新日期：2007-05-01 00:00:00

abstract：:A patient with neurogenic pulmonary edema was successfully treated with the alpha-blocking agent, chlorpromazine. A pathophysiologic basis for this drug's efficacy is discussed. ...

journal_title：Critical care medicine

authors： Wohns RN,Tamas L,Pierce KR,Howe JF

更新日期：1985-03-01 00:00:00

abstract：OBJECTIVE:To analyze plasma interferon-gamma and interleukin-10 concentrations in patients with systemic meningococcal disease and patients with severe Gram-positive septic shock caused by Streptococcus pneumoniae or Staphylococcus aureus. To study the in vitro cytokine (interferon-gamma and interleukin-10) responses i...

journal_title：Critical care medicine

authors： Bjerre A,Brusletto B,Høiby EA,Kierulf P,Brandtzaeg P

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVES:To determine bronchoalveolar lavage (BAL) fluid concentrations of keratinocyte growth factor (KGF) and hepatocyte growth factor (HGF), two potent growth factors for alveolar type II epithelial cells, in patients with acute respiratory distress syndrome (ARDS). DESIGN:Prospective study. SETTING:An adult tra...

journal_title：Critical care medicine

authors： Stern JB,Fierobe L,Paugam C,Rolland C,Dehoux M,Petiet A,Dombret MC,Mantz J,Aubier M,Crestani B

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVES:To characterize the rates of accidental removal of endotracheal tubes, nasogastric tubes, central venous catheters, and arterial catheters. To assess the efficacy of corrective measures aimed at reducing the accidental removal of these devices. DESIGN:Prospective, observational, and interventional study. S...

journal_title：Critical care medicine

authors： Carrión MI,Ayuso D,Marcos M,Paz Robles M,de la Cal MA,Alía I,Esteban A

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVES:Extracorporeal membrane oxygenation is used to stabilize severe cardiocirculatory and/or respiratory failure. However, extracorporeal membrane oxygenation is associated with a coagulopathy characterized by thromboembolic and hemorrhagic complications. This study aimed to characterize the pathomechanism of th...

journal_title：Critical care medicine

authors： Granja T,Hohenstein K,Schüssel P,Fischer C,Prüfer T,Schibilsky D,Wendel HP,Jaschonek K,Serna-Higuita L,Schlensak C,Häberle H,Rosenberger P,Straub A

更新日期：2020-05-01 00:00:00