Abstract:
OBJECTIVES:To investigate the relation between shift work and death from ischaemic heart disease (IHD). METHODS:A nested case-control approach was used. The cohort comprised male manual workers who joined an industrial company aged 50 years or under between 1 January 1950 and 31 December 1992 and worked there for at least one month. Cases were 467 cohort members who died during the same period aged 75 years or under, with ischaemic heart disease (IHD) (international classification of diseases (ICD) 410-414) coded from the death certificate. For each case a control worker was chosen, who joined the company at the same age and in the same period but who survived the case. Work status (shift work or day work) was assigned to cases for their entire employment and to controls for that part of their employment which preceded the matching case's death. The main source of information was historical personnel records containing pay codes which differed for day work and shift work. Information on weight, height, blood pressure, and smoking from a pre-employment medical was available. RESULTS:Two thirds of subjects had been employed for at least one month as shift workers and there was evidence that they had slightly better health at recruitment than day workers. The odds ratio for shift workers during the period starting 10 years after shift work began, and after adjustment for height, body mass index, blood pressure, smoking, duration of employment, and job status (skilled or unskilled) was 0.90 (90% confidence interval (90% CI): 0.68-1.21). There was no relation between risk of IHD death, and duration of shift work, but there was evidence of a reduced risk when actively employed as a shift worker, together with an increased risk in the first five years after leaving shift work to do day work. CONCLUSIONS:Shift work did not increase the risk of death from ischaemic heart disease in this study. Those workers with poorer cardiovascular health may be under represented in groups with longer shift work experience because of health related selection out of shift work.
journal_name
Occup Environ Medjournal_title
Occupational and environmental medicineauthors
McNamee R,Binks K,Jones S,Faulkner D,Slovak A,Cherry NMdoi
10.1136/oem.53.6.367subject
Has Abstractpub_date
1996-06-01 00:00:00pages
367-73issue
6eissn
1351-0711issn
1470-7926journal_volume
53pub_type
杂志文章abstract:OBJECTIVES:To investigate changes in digital circulation during and after exposure to hand transmitted vibration. By studying two frequencies and two magnitudes of vibration, to investigate the extent to which haemodynamic changes depend on the vibration frequency, the vibration acceleration, and the vibration velocity...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.54.8.566
更新日期:1997-08-01 00:00:00
abstract:AIM:To compare two different methods for assessment of postural load and duration of computer use in office workers. METHODS:The study population existed of 87 computer workers. Questionnaire data about exposure were compared with exposures measured by a standardised or objective method. Measuring true exposure to pos...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.013219
更新日期:2004-12-01 00:00:00
abstract::Fluorocarbons are widely used in industry, and manifestations of inhalation toxicity include polymer fume fever, reactive airways dysfunction, and bronchospasm. Only seven cases of alveolitis occurring acutely after inhalation have been reported. This paper presents four cases of toxic pneumonitis due to direct inhala...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.015784
更新日期:2005-06-01 00:00:00
abstract:AIMS:To test whether (1) physically demanding work is less frequent for older than younger employees, and whether (2) the association of physically demanding work with decline of physical functioning is stronger for older employees than their younger counterparts. The gender differences in these associations were exami...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.014035
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVE:Interpretation of epidemiological studies on health effects from mobile phone use is hindered by uncertainties in the exposure assessment. We used a newly developed smartphone application (app) to validate self-reported mobile phone use and behaviour among adults. METHODS:107 participants (mean age 41.4 year...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2015-102808
更新日期:2015-11-01 00:00:00
abstract:AIMS:To examine the hypothesis that people with benign pleural disease or asbestosis have an increased risk of malignant mesothelioma beyond that attributable to their degree of asbestos exposure. METHODS:Former workers and residents of the crocidolite mining and milling town of Wittenoom are participating in a cancer...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.018531
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVES:Animal studies suggest that exposure to pesticides may alter thyroid function; however, few epidemiologic studies have examined this association. We evaluated the relationship between individual pesticides and thyroid function in 679 men enrolled in a substudy of the Agricultural Health Study, a cohort of li...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2017-104431
更新日期:2018-02-01 00:00:00
abstract:AIMS:To investigate the acute systemic inflammatory response to welding fume exposure. METHODS:Twenty four welders (42% smokers) and 13 non-exposed controls (23% smokers) were monitored at a welding school. Exposure to fine particulate matter (PM2.5) was assessed using cyclone samplers. Markers of systemic inflammatio...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.014795
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVES:To examine if the occurrence of different cancers was increased among rubber workers, as the highest known exposures of humans to nitrosamines have occurred in the rubber industry. METHODS:A cohort of 8933 rubber workers (hired after 1 January 1950, still active or retired on 1 January 1981 and employed for...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.57.3.180
更新日期:2000-03-01 00:00:00
abstract:OBJECTIVE:This study investigated the association between long-term exposure to black smoke (BS) air pollution and mortality in two related Scottish cohorts with 25 years of follow-up. METHODS:Risk factors were collected during 1970-1976 for 15331 and 6680 participants in the Renfrew/Paisley and Collaborative cohorts ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2011-100600
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:This study assessed the efficacy of preventive measures in a graphite electrode plant aimed at reducing occupational exposure to polycyclic aromatic hydrocarbons (PAHs). METHODS:Electrode workers (n = 146) answered a questionnaire and provided an end of shift urine sample. Urinary 1-hydroxypyrene (1-hpur), a...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.55.6.401
更新日期:1998-06-01 00:00:00
abstract:OBJECTIVE:The aim was to investigate associations between exposure to mineral fibres and dust, and cancer in subsites within the large bowel. DESIGN:Pooled retrospective cohort studies. SUBJECTS AND SETTINGS:Blue collar workers, employed for at least one year in different trades; asbestos cement or cement workers (n ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.51.2.95
更新日期:1994-02-01 00:00:00
abstract:OBJECTIVES:Recently, diesel motor exhaust (DME) has been classified as a known human carcinogen. We used data from epidemiological studies of diesel exposures to perform a quantitative risk assessment to calculate DME exposure levels, expressed as elemental carbon (EC), corresponding to acceptable risk (AR) and maximum...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2016-103977
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:To investigate possible neurotoxic effects in groups of aluminium pot room and foundry workers, aluminium welders, and a small group of workers exposed to aluminium in the production of flake powder. METHODS:Exposure to aluminium was evaluated with aluminium concentrations in blood and urine as well as a que...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.58.7.453
更新日期:2001-07-01 00:00:00
abstract:OBJECTIVE:This study was undertaken to assess whether contaminated personal clothing worn beneath a coverall (normal workwear) is a source of potentially significant dermal exposure to polycyclic aromatic hydrocarbons (PAHs) in coal liquefaction workers. METHODS:An intervention study was conducted over a two week peri...
journal_title:Occupational and environmental medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/oem.52.9.600
更新日期:1995-09-01 00:00:00
abstract:AIMS:To determine the factors that affect why some infants receive higher exposures relative to the mother's body burden than do others. METHODS:A total of 159 mother-infant pairs from a cohort of women receiving prenatal care at Magee-Womens Hospital in Pittsburgh, PA from 1992 to 1995 provided blood samples at deliv...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2003.012492
更新日期:2005-04-01 00:00:00
abstract:OBJECTIVES:To better understand the relations between occupational exposure, blood antioxidant enzyme activities, total plasma antioxidant concentration, and the severity of coal workers' pneumoconiosis (CWP). METHODS:Blood samples were obtained from miners without CWP exposed to low dust concentrations for > or = 4 y...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.55.8.533
更新日期:1998-08-01 00:00:00
abstract:OBJECTIVES:We evaluated the association between exposure to polycyclic aromatic hydrocarbons (PAHs) and immunological measurements using blood samples from coke oven workers exposed to high and low PAH levels. METHODS:A population-based cross-sectional study was conducted from 2008-2009 with coke oven workers and stee...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2010.055020
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVES:Introduced in the UK in 2010, the fit note was designed to address the problem of long-term sickness absence. We explored (1) associations between demographic variables and fit note receipt, 'maybe fit' use and long-term conditions, (2) whether individuals with long-term conditions receive more fit notes and...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2019-106035
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVES:The main objective of this study was to investigate exposure-response relations between adverse musculoskeletal outcomes and ergonomic exposure variables. METHODS:A cross sectional analytical study was conducted in 11 factories from seven sectors of manufacturing industry in South Africa. Exposure to workpl...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.52.1.46
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:To estimate the fraction of carpal tunnel syndrome (CTS) that is attributable to work in the total adult population of the island of Montreal. METHODS:The population consisted of 1.1 million people 20-64 years of age, with 73.2% of men and 60.6% of women employed. The rates of first surgery for CTS were comp...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.54.7.519
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVES:To verify in vivo whether lung cinescintigraphy confirms the effect of asbestos on the patency of the smallest airways and on the efficiency of mucociliary clearance in asbestos cement workers. METHODS:39 male subjects were examined: 30 asbestos cement workers and nine workers never exposed to occupational ...
journal_title:Occupational and environmental medicine
pub_type: 临床试验,杂志文章
doi:10.1136/oem.53.9.628
更新日期:1996-09-01 00:00:00
abstract:OBJECTIVES:The number of nuclear medicine procedures has increased substantially over the past several decades, with uncertain health risks to the medical workers who perform them. We estimated risks of incidence and mortality from cancer and circulatory disease associated with performing procedures involving the use o...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2015-102834
更新日期:2015-11-01 00:00:00
abstract:AIMS:To analyse the effects of age and occupational factors on both the incidence and the disappearance of chronic neck and shoulder pain after a five year follow up period. METHODS:A prospective longitudinal investigation (ESTEV) was carried out in 1990 and 1995 in seven regions of France. A random sample of male and...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.59.8.537
更新日期:2002-08-01 00:00:00
abstract:OBJECTIVES:The study investigated the utility of unmetabolised naphthalene (Nap) and phenanthrene (Phe) in urine as surrogates for exposures to mixtures of polycyclic aromatic hydrocarbons (PAHs). METHODS:The report included workers exposed to diesel exhausts (low PAH exposure level, n = 39) as well as those exposed t...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2008.041418
更新日期:2009-02-01 00:00:00
abstract::Aerosol sampling has evolved with changes in technology and our understanding of the importance of assessing the biologically relevant fractions of the total aerosol. During the past decade there has been international agreement on the definitions for the inhalable, thoracic, and respirable fractions and instruments h...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,评审
doi:10.1136/oem.56.11.747
更新日期:1999-11-01 00:00:00
abstract:OBJECTIVES:Benzene is an established animal and human carcinogen. The mechanism of benzene toxicity, particularly its leukaemogenic effect, is not fully understood. The modified base 8-hydroxy-deoxyguanosine (8-OHdG) is a sensitive marker of the DNA damage due to hydroxyl radical attack at the C8 of guanine. This damag...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.51.11.739
更新日期:1994-11-01 00:00:00
abstract:OBJECTIVES:To investigate the relation between fluctuations in personal exposure to nitrogen dioxide (NO(2)) in school children and changes in outdoor NO(2) concentrations. METHODS:114 Asthmatic school children aged 7-12 years were recruited from the Southampton area. Weekly average personal exposures to NO(2) were me...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.57.7.472
更新日期:2000-07-01 00:00:00
abstract:OBJECTIVES:To update mortality for 34 560 employees from diverse operating segments of a Canadian petroleum company; and to investigate potential relations with occupational factors. METHODS:Employees from 1964-83 were linked to the Canadian mortality data base to provide 11 years additional follow up. There were 6760...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.57.9.595
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVES:To appraise epidemiological evidence of the purported association between residential exposure to power frequency magnetic fields and adult cancers. METHODS:Literature review and epidemiological evaluation. RESULTS:Seven epidemiological studies have been conducted on the risk of cancer among adults in rela...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,评审
doi:10.1136/oem.53.8.505
更新日期:1996-08-01 00:00:00