Abstract:
:Four pigeons responded under a fixed-interval 8-min schedule of food delivery in which the amount of food delivered at the end of each interval depended on performance during the interval (i.e., a correlated schedule). Specifically, duration of access to grain was contingent upon the number of responses made during the first 4 min of the interval. This differential outcome did not affect response rates or patterning relative to performance under a simple fixed-interval 8-min schedule. Behavior under the correlated schedule was then investigated under doses of cocaine ranging from 0.3 to 10.0 mg/kg. A bitonic dose-response function was obtained for response rates and the time with head in the food hopper, whereas dose-dependent decreases were observed in the mathematical index of curvature (Fry, Kelleher, & Cook, 1960). The dose that produced the greatest increase in the head-in-hopper time was then administered prior to each session. Following repeated administration of cocaine, disruptions in response patterning were attenuated for all 4 pigeons; tolerance was also observed to the rate-increasing effects and increased head-in-hopper time for 2 pigeons after chronic cocaine administration. Tolerance therefore developed despite the fact that the initial effect of cocaine was to increase the amount of food obtained.
journal_name
J Exp Anal Behavjournal_title
Journal of the experimental analysis of behaviorauthors
Miller ML,Brodkorb GW,Branch MNdoi
10.1901/jeab.2001.76-217subject
Has Abstractpub_date
2001-09-01 00:00:00pages
217-34issue
2eissn
0022-5002issn
1938-3711journal_volume
76pub_type
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journal_title:Journal of the experimental analysis of behavior
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journal_title:Journal of the experimental analysis of behavior
pub_type: 杂志文章
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journal_title:Journal of the experimental analysis of behavior
pub_type: 杂志文章
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journal_title:Journal of the experimental analysis of behavior
pub_type: 杂志文章
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更新日期:1964-05-01 00:00:00
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journal_title:Journal of the experimental analysis of behavior
pub_type: 杂志文章
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更新日期:1994-07-01 00:00:00
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journal_title:Journal of the experimental analysis of behavior
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
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更新日期:2018-05-01 00:00:00
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pub_type: 杂志文章
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journal_title:Journal of the experimental analysis of behavior
pub_type: 杂志文章
doi:10.1901/jeab.1978.30-69
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journal_title:Journal of the experimental analysis of behavior
pub_type: 杂志文章
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journal_title:Journal of the experimental analysis of behavior
pub_type: 杂志文章
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更新日期:1973-03-01 00:00:00