Abstract：
:The authors examined 25 children with allergic rhinitis, who were sensitive to grass, weed and tree pollens. During the allergic season nasal lavage was performed then repeated after 4 weeks of loratadine treatment. Tryptase, IL-5, ECP, TNF-alpha and RANTES levels were measured from the nasal lavage fluid. Tryptase, IL-5, and ECP levels were decreased significantly while the decrease of RANTES and TNF-alpha levels was not significant. The authors emphasize that loratadine is an effective anti-inflammatory drug which affects the early and late phase of immediate hypersensitivity. In the moderate cases loratadine is enough to relieve the symptoms, while in the severe forms anti-allergic eye drops and nasal antihistamine or steroid spray has to be added.
journal_name
Orv Hetiljournal_title
Orvosi hetilapauthors
Kósa L,Kovács N,Halász A,Zsigmond Gsubject
Has Abstractpub_date
2001-08-26 00:00:00pages
1843-5issue
34eissn
0030-6002issn
1788-6120journal_volume
142pub_type
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