Influence of culture media and multidrug resistance on the wheat germ agglutinin (WGA) glycocytochemical expression of two human glioblastoma cell lines.

abstract：:We have previously reported that the presence of an extracapsular invasion (ECI) at sentinel lymph nodes (SLNs) is a strong predictor of non-SLN metastasis in breast cancer. We hypothesized that(18)F-fluorodeoxyglucose (FDG) uptake by metastatic SLNs reflects invasive disease, or ECI. In this study, we evaluated the a...

journal_title：Anticancer research

authors： Fujii T,Yajima R,Tatsuki H,Kuwano H

更新日期：2016-04-01 00:00:00

abstract：:Gallic acid induced apoptotic cell death in human promyelocytic leukemia HL-60 cells. The effect of gallic acid was significantly reduced by blocking the free hydroxyl or carboxyl group with acetyl, methyl, ethyl, n-propyl or isoamyl group. This was paralleled with the decrease in the intensity of both gallate radical...

journal_title：Anticancer research

authors： Sakagami H,Satoh K,Hatano T,Yoshida T,Okuda T

更新日期：1997-01-01 00:00:00

abstract：:For the selection of patients responding well to lentinan, we performed two immunological analysis of patients. Flow cytometric analysis was obtained from peripheral blood lymphocytes; the patients who had greater than 2.5 ratio of [CD11(-) CD8(+)/CD11(+) CD8(+) after treatment]/[CD11(-) CD8(+)/CD11(+) CD8(+) before t...

journal_title：Anticancer research

authors： Matsuoka H,Seo Y,Wakasugi H,Saito T,Tomoda H

更新日期：1997-07-01 00:00:00

abstract：:Three monoclonal antiidiotypic antibodies (AIA) to MOPC 315 IgA, G3 (IgG2b), A2 (IgG1) and D10 (a hybrid molecule consisting of gamma 1 and gamma 2a heavy chains), were characterized with respect to their binding constants (Ka) to MOPC 315 mouse myeloma cells. The Ka of G3 and A2 was 10(8)/mole; and that of D10 was 3 ...

journal_title：Anticancer research

authors： Marks A,Baumal R,Lei M,Ahmad A,Liu E

更新日期：1985-07-01 00:00:00

abstract：:Selective delivery of a high level of Mitomycin C (MMC) in intraperitoneal disseminated lesions was studied using a new dosage form of MMC, called MMC-CH. Intracavitary MMC-CH delivered a much higher level of MMC selectively to intraperitoneal tissues, with a much lower level of MMC in the whole body, in comparison wi...

journal_title：Anticancer research

authors： Hagiwara A,Takahashi T,Lee R,Ueda T,Takeda M,Itoh T

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:The albumin-bilirubin (ALBI) grade assesses the severity of liver dysfunction in patients with hepatocellular carcinoma. Herein we investigated the prognostic significance of the combination of the ALBI grade with serum carbohydrate antigen 19-9 (CA 19-9) concentration, the most frequently used tumor marker ...

journal_title：Anticancer research

authors： Yagyu T,Saito H,Sakamoto T,Uchinaka EI,Morimoto M,Amisaki M,Watanabe J,Tokuyasu N,Honjo S,Ashida K,Fujiwara Y

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND/AIM:Cytological analysis for diagnosing malignant pleural effusion associated with lung adenocarcinoma (Ad-MPE) shows limited sensitivity and novel diagnostic biomarkers are needed. The aim of this study was to evaluate the profile of four microRNAs (miRNAs) in exosomes in Ad-MPE and benign (non-neoplastic) ...

journal_title：Anticancer research

authors： Tamiya H,Mitani A,Saito A,Ishimori T,Saito M,Isago H,Jo T,Yamauchi Y,Tanaka G,Nagase T

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND/AIM:We evaluated the efficacy and safety of carbon-ion radiotherapy (CIRT) alone for Stage III non-small-cell lung cancer (NSCLC). PATIENTS AND METHODS:Data of 65 patients (median age=73 years) with Stage III NSCLC who underwent CIRT alone in the QST Hospital, Chiba, Japan, between 1997 and 2015 were retros...

journal_title：Anticancer research

authors： Anzai M,Yamamoto N,Hayashi K,Nakajima M,Nomoto A,Ogawa K,Tsuji H

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND AND AIM:The clinical efficiency of cisplatin (CDDP) against gastric cancer is often limited by the development of resistance. A third-generation platinum-containing agent, oxaliplatin (L-OHP), has been introduced for treating gastric cancer. Here, we studied oxaliplatin in vitro to reveal the mechanism of ac...

journal_title：Anticancer research

authors： Tozawa K,Oshima T,Kobayashi T,Yamamoto N,Hayashi C,Matsumoto T,Miwa H

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Several attempts have been made to determine whether interphase fluorescence in situ hybridization (I-FISH) on bone marrow or peripheral blood specimens is a good alternative to conventional cytogenetics (CC) in calculating the residual proportion of Philadelphia (Ph) chromosome-positive cells during treatme...

journal_title：Anticancer research

authors： Douet-Guilbert N,Morel F,Le Charpentier T,Le Bris MJ,Herry A,Morice P,Bourquard P,Abgrall JF,Berthou C,De Braekeleer M

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND/AIM:In pancreatic cancer, where the microenvironment is extremely hypoxic, analyzing signal transduction under hypoxia is thought to be significantly important. By investigating microarray analysis of pancreatic cancer cells cultured under both normoxia and hypoxia, we found that the expression of leukocyte ...

journal_title：Anticancer research

authors： Yamasaki A,Nakayama K,Imaizumi A,Kawamoto M,Fujimura A,Oyama Y,Nagai S,Yanai K,Onishi H

更新日期：2017-12-01 00:00:00

abstract：:Using serum-free conditions, human monocyte-derived dendritic cells (MoDCs) tend to mature insufficiently in a T(H)1-polarizing direction under approved and standardized clinical conditions. However, for the initiation of an efficient tumour antigen-specific cytotoxic T-cell response, the induction of a distinct T(H)1...

journal_title：Anticancer research

authors： Hildenbrand B,Lorenzen D,Sauer B,Hertkorn C,Freudenberg MA,Peters JH,Nesselhut T,Unger C,Azemar M

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND/AIM:Hypoxia offers resistance to therapy in human solid tumors. The aim of the study was to investigate whether SN-38, the active metabolite of irinotecan, acts as a radiosensitizer through inhibition of hypoxia-inducible factor (HIF)-1α in the human colorectal cancer (CRC) cells. MATERIALS AND METHODS:HT29...

journal_title：Anticancer research

authors： Okuno T,Kawai K,Hata K,Murono K,Emoto S,Kaneko M,Sasaki K,Nishikawa T,Tanaka T,Nozawa H

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND/AIM:The clinical significance of surgery for secondary small intestinal non-Hodgkin's lymphomas (NHL) remains unknown. This study aimed to investigate the efficacy of resection for both primary and secondary small intestinal NHL. PATIENTS AND METHODS:Twenty patients with small intestinal lymphoma who underw...

journal_title：Anticancer research

authors： Iida T,Nozawa H,Sonoda H,Toyama K,Kawai K,Hata K,Tanaka T,Nishikawa T,Sasaki K,Shuno Y,Kaneko M,Murono K,Emoto S,Ishii H,Kurokawa M,Ishihara S

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND/AIM:This study assessed the toxicity and activity of biweekly docetaxel and S-1 combination therapy in elderly patients with advanced gastric cancer. PATIENTS AND METHODS:One-hundred and thirteen patients were enrolled: 35 were 75 years old or more. The objective response rate, toxicity, progression-free su...

journal_title：Anticancer research

authors： Kunisaki C,Takahashi M,Ono HA,Hasegawa S,Tsuchida K,Oshima T,Ota M,Fukushima T,Tokuhisa M,Izumisawa Y,Takagawa R,Kimura J,Kosaka T,Makino H,Akiyama H,Endo I

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND/AIM:The toxicity of the proteasome inhibitor MG132 was tested alone and combined either with the topoisomerase I inhibitor topotecan or the topoisomerase II inhibitor etoposide against a panel of 18 cell lines representing six pediatric tumor types. MATERIALS AND METHODS:MG132, topotecan, etoposide and thei...

journal_title：Anticancer research

authors： Destanovic E,Boos J,Lanvers-Kaminsky C

更新日期：2018-07-01 00:00:00

abstract：UNLABELLED:The present study evaluated the frequency of the polymorphism of Interleukin-6 (IL6) in women positive for E6/E7 Human Papillomavirus (HPV) (n=152) and women negative for HPV (n=238), 390 women in total. Material for analysis was obtained at the Federal University of São Paulo. Interleukin-6 polymorphism was...

journal_title：Anticancer research

authors： Porto CR,De Oliveira Kleine JP,Longatto Filho A,Da Silva ID

更新日期：2014-07-01 00:00:00

abstract：:Chloroform (CHCl3) is an established rodent carcinogen and a prevalent contaminant of chlorine-disinfected drinking water. Thus in the United States CHCl3, along with other trihalomethanes, is regulated not to exceed 100 ppb in potable water. Recently, several studies have shown that CHCl3 also has anti-cancer propert...

journal_title：Anticancer research

authors： Daniel FB,Reddy TV,Stober JA,Olson GR

更新日期：1991-03-01 00:00:00

abstract：:The aim of this study was to compare the accuracy of 18-fluoro-2-deoxyglucose (FDG) positron emission tomography (PET) and thallium-201 (Tl-201) single photon emission computed tomography (SPECT) in differentiating recurrent/residual nasopharyngeal carcinomas (NPC) from post-radiotherapy (RT) changes in patients with ...

journal_title：Anticancer research

authors： Tsai MH,Huang WS,Tsai JJ,Chen YK,Changlai SP,Kao CH

更新日期：2003-07-01 00:00:00

abstract：:This report describes a precise molecular analysis of a rare case of Philadelphia chromosome (Ph) positive acute myeloid leukemia (AML) (FAB classification M2). Phenotypic markers were positive for cells of the myeloid lineage, but negative for B cell and T cell lineage. The leukemic cells carried a Philadelphia chrom...

journal_title：Anticancer research

authors： Yoshida A,Kishi S,Kita K,Kamada N,Nakamura T,Ueda T

更新日期：1997-01-01 00:00:00

abstract：:Urine and serum samples from a group of 359 individuals were studied in order to evaluate the usefulness of TPA in patients with urological cancers. Serum was taken from 110 people at 12 noon (S1), 5 pm (S2), and 8 am the following day (S3), while urine samples were collected from 73 individuals over three time interv...

journal_title：Anticancer research

authors： Costello CB,Kumar S

更新日期：1986-07-01 00:00:00

abstract：:The members of the matrix metalloproteinase family (MMP) have the ability to degrade macromolecules of the extracellular matrix and are responsible for tumor invasion and infiltration, limiting the effectiveness of the neurosurgical resection of brain tumors. Among the glial brain tumors, astrocytomas and oligodendrog...

journal_title：Anticancer research

authors： Thorns V,Walter GF,Thorns C

更新日期：2003-09-01 00:00:00

abstract：:Estrogen receptor activation in hormone dependent cells (MCF-7 and T47D) and hormone independent cells (MDA-MB-231) was measured by bioluminescence in stably transfected human breast cancer MCF-7, T47D and MDA-MB-231 cell lines with a reporter gene which allows expression of the firefly luciferase enzyme under the con...

journal_title：Anticancer research

authors： Le Bail JC,Allen K,Nicolas JC,Habrioux G

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinase 9 (MMP-9) plays an important role in cancer invasion and metastasis. The relationship between serum MMP-9 levels and clinicopathological factors in gastric cancer patients is not clear. MATERIALS AND METHODS:Preoperative serum was obtained from 170 patients who had undergone gastrec...

journal_title：Anticancer research

authors： Shen KH,Chi CW,Lo SS,Kao HL,Lui WY,Wu CW

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Different oncogenes (Fas and bcl-2) and diverse cytokines (IL-10 and alfa-TNF) may have an effect on the regulation of apoptosis. The majority of studies to date have evaluated only one or two of these elements independently and it is difficult to obtain a global view of apoptosis disregulation in the pathog...

journal_title：Anticancer research

authors： Miret C,Font J,Molina R,Garcia-Carrasco M,Filella X,Ramos M,Cervera R,Ballesta A,Ingelmo M

更新日期：2001-07-01 00:00:00

abstract：:The role of serum tumor markers in lung cancer has not been defined. It is widely believed that almost all neoplasms produce at least a few substances, but the identity of most of the known substances has not been correlated with a positive role in either the diagnosis or prognosis of patients with these neoplasms. We...

journal_title：Anticancer research

authors： Tarro G,Esposito C,Perna A,Claudio PP,Giordano A

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Cervical cancer constitutes the second most common cancer in women. Estrogen promotes development of cervical cancer in cells infected with high risk human papillomaviruses (HPVs). We asked whether the phytochemical indole-3-carbinol (I3C) has anti-estrogenic activities in cervical cells with the goal of pre...

journal_title：Anticancer research

authors： Yuan F,Chen DZ,Liu K,Sepkovic DW,Bradlow HL,Auborn K

更新日期：1999-05-01 00:00:00

abstract：:The prognostic and predictive role of p53 overexpression in breast cancer samples is usually investigated by using molecular biology or immunohistochemical methods. However, the results are to date controversial, and this is in part due to the methodological pitfalls of both the methods. To study the possibility of ov...

journal_title：Anticancer research

authors： Dittadi R,Brazzale A,Mione R,Di Fresco S,Gatti C,Vinante O,Bassan F,Nascimben O,Gion M

更新日期：1997-11-01 00:00:00

abstract：:Herein we report on a case of synchronous large gastrointestinal stromal tumor (GIST) and adenocarcinoma of the stomach treated with radical surgery following neoadjuvant therapy with imatinib mesylate. A 58-year-old man was referred to our hospital with a large mass in the peritoneal cavity. Abdominal computed tomogr...

journal_title：Anticancer research

authors： Namikawa T,Munekage E,Munekage M,Maeda M,Yatabe T,Kitagawa H,Sakamoto K,Obatake M,Kobayashi M,Hanazaki K

更新日期：2016-04-01 00:00:00

abstract：:Metallopanstimulin (MPS) is a 9.5-kDal subunit "zinc finger" protein which is expressed in a wide variety of actively proliferating cells and tumor tissues (J. Biol. Chem. 268:21198-21204, 1993; Cell Growth & Diff. 5:811-825, 1994). A sensitive and specific radioimmunoassay (RIA) has been developed to measure circulat...

journal_title：Anticancer research

authors： Fernandez-Pol JA

更新日期：1996-07-01 00:00:00