Intravenous iron therapy for severe pregnancy anemia with high erythropoietin levels.

Abstract:

BACKGROUND:To demonstrate that intravenous (IV) iron therapy rapidly can secure the physiologic correction of severe nonhemorrhagic anemia more safely than blood component therapy and recombinant erythropoietin treatment. CASE:An 18-year-old woman with beta-thalassemia in her 33rd week of gestation had a hemoglobin level of 4.8 g/dL and an erythropoietin value of 191 mU/mL. After IV iron administration, erythropoietin rapidly decreased and hemoglobin increased to 8.1 g/dL in correlation with estriol elevation. A healthy infant with normal hemoglobin and ferritin levels was delivered at 42 weeks by cesarean. CONCLUSION:Intravenous iron administration rapidly corrected severe nonhemorrhagic anemia in a pregnant patient and may produce an improvement in fetal indices. High erythropoietin levels predict a good response to iron and may obviate the need for blood transfusions and recombinant erythropoietin administration, at least until this therapy is tried.

journal_name

Obstet Gynecol

authors

Carretti N,Paticchio MR,Eremita GA

doi

10.1016/s0029-7844(97)00261-5

subject

Has Abstract

pub_date

1997-10-01 00:00:00

pages

650-3

issue

4 Pt 2

eissn

0029-7844

issn

1873-233X

journal_volume

90

pub_type

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