Investigating inflammatory bowel disease--white cell scanning, radiology, and colonoscopy.

Abstract:

OBJECTIVE:To evaluate different methods of examination of the bowel in suspected inflammatory bowel disease. DESIGN:Prospective investigation of all children over a three year period with suspected inflammatory bowel disease. A technetium-99m-HMPAO labelled white cell scan (Tc-WCS), barium follow through examination (Ba-FT), and colonoscopy plus biopsy were undertaken. SETTING:Great Ormond Street Hospital for Children, London. SUBJECTS:39 children (20 male and 19 female), median age 12.1 years (range 3.9-15.1 years). MAIN OUTCOME MEASURES:There was total agreement in 21/39 cases, positive in 16, and negative in five. Of 31 histologically proved cases, positive results were obtained in 28 Tc-WCSs (sensitivity 90%), 10 of 24 Ba-FTs (sensitivity 42%), and 27 colonoscopies (sensitivity 87%). CONCLUSION:The Tc-WCS is sensitive, specific, and non-invasive and should be a first line investigation. Ba-FT with a high radiation burden and relatively low sensitivity requires its role to be redefined. Colonoscopy, with endoscopic biopsy, has a high pick-up rate where facilities and expertise exist.

journal_name

Arch Dis Child

authors

Jobling JC,Lindley KJ,Yousef Y,Gordon I,Milla PJ

doi

10.1136/adc.74.1.22

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

22-6

issue

1

eissn

0003-9888

issn

1468-2044

journal_volume

74

pub_type

临床试验,杂志文章
  • Facilities for the school health team.

    abstract::Results of a questionnaire returned by 20 doctors giving information of 249 schools showed that many of the rooms made available to school health services are inadequate in terms of physical resources and privacy. A higher set of standards is recommended to enable schools and pupils to derive maximum benefit from comm...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.70.6.542

    authors: Henshelwood J,Polnay L

    更新日期:1994-06-01 00:00:00

  • Analysis of paediatric long-term ventilation incidents in the community.

    abstract:AIM:To describe the nature and causes of reported patient safety incidents relating to care in the community for children dependent on long-term ventilation with the further aim of improving safety. METHODS:We undertook an analysis of patient safety incident data relating to long-term ventilation in the community usin...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2019-317965

    authors: Nawaz RF,Page B,Harrop E,Vincent CA

    更新日期:2020-05-01 00:00:00

  • Physical treatment of fever.

    abstract::Fever is a common symptom of childhood illness, and much time and effort is spent in the pursuit of reducing high temperature. Although antipyretic drugs are the main form of treatment, this report considers the part that physical treatments might play in reducing the temperature of febrile children. Such treatments i...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.82.3.238

    authors: Purssell E

    更新日期:2000-03-01 00:00:00

  • Management of severe acute malnutrition in low-income and middle-income countries.

    abstract::Kwashiorkor and marasmus, collectively termed severe acute malnutrition (SAM), account for at least 10% of all deaths among children under 5 years of age worldwide, virtually all of them in low-income and middle-income countries. A number of risk factors, including seasonal food insecurity, environmental enteropathy, ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2014-306026

    authors: Trehan I,Manary MJ

    更新日期:2015-03-01 00:00:00

  • Realities of paediatric pharmacotherapy in the developing world.

    abstract::Diseases causing high mortality in children under 5 years of age in resource limited settings (RLS) could be treated if children in these countries had access to existing medicines. It took 30 years before the WHO Essential Medicines List (EML) considered the issue of medicines for children, with the first EML for chi...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,评审

    doi:10.1136/adc.2009.180000

    authors: Hoppu K,Sri Ranganathan S,Dodoo AN

    更新日期:2011-08-01 00:00:00

  • How to avoid paediatric medication errors: a user's guide to the literature.

    abstract::The National Health Service, in its report An organisation with memory, has called for a fundamental rethinking of the way the healthcare system learns from error. The NHS further details its goal to reduce serious medication errors by 40% in a second report entitled Building a safer NHS: improving medication safety. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,评审

    doi:10.1136/adc.2003.048827

    authors: Walsh KE,Kaushal R,Chessare JB

    更新日期:2005-07-01 00:00:00

  • Socioeconomic inequalities in risk of congenital anomaly.

    abstract:AIMS:To investigate socioeconomic inequalities in the risk of congenital anomalies, focusing on risk of specific anomaly subgroups. METHODS:A total of 858 cases of congenital anomaly and 1764 non-malformed control births were collected between 1986 and 1993 from four UK congenital malformation registers, for the purpo...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,多中心研究

    doi:10.1136/adc.82.5.349

    authors: Vrijheid M,Dolk H,Stone D,Abramsky L,Alberman E,Scott JE

    更新日期:2000-05-01 00:00:00

  • Effects of overweight on lung function.

    abstract::Spirometric data from 1586 healthy children, who did not smoke, were analysed to examine the effects of overweight as measured by the body mass index (weight/height2) on lung function. Overweight (72 boys, 88 girls) was defined as on or above the 90th percentile weight for height. After having controlled for the confo...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.65.5.512

    authors: Fung KP,Lau SP,Chow OK,Lee J,Wong TW

    更新日期:1990-05-01 00:00:00

  • Overtreatment in threshold and developed countries.

    abstract::In acute paediatrics, overtreatment and overdiagnosis is encountered in threshold and developed countries. The reason for overtreatment may be similar in the two settings, namely the mere availability of invasive procedures, which may lead to their inappropriate use. Physiological healing processes should be integrate...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,评审

    doi:10.1136/adc.2007.124479

    authors: Frey B

    更新日期:2008-03-01 00:00:00

  • Minor congenital anomalies and ataxic cerebral palsy.

    abstract::The incidence of minor congenital anomalies was examined in 36 patients with ataxic cerebral palsy, in unaffected family members, and in 100 unrelated control subjects. None of the control subjects or family members had more than four anomalies, and 25 of 36 (69%) of the patients had more than four. The distribution o...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.64.4.557

    authors: Miller G

    更新日期:1989-04-01 00:00:00

  • Prevalence and distribution of petechiae in well babies.

    abstract:AIMS:To determine the prevalence of petechial spots in well babies. METHODS:A total of 116 babies under the age of 12 months were fully examined at child health surveillance clinics. The number and site of petechiae were recorded together with details of possible causes. RESULTS:A total of 27.6% of babies had one or ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.86.4.291

    authors: Downes AJ,Crossland DS,Mellon AF

    更新日期:2002-04-01 00:00:00

  • Auditory integration training and other sound therapies for autism spectrum disorders: a systematic review.

    abstract:OBJECTIVES:To determine the effectiveness of auditory integration training (AIT) or other methods of sound therapy in people with autism spectrum disorders (ASD). STUDY DESIGN:A systematic review was carried out of randomised controlled trials (RCTs) of adults or children with ASD. Meta-analysis was attempted. RESULT...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,meta分析,评审

    doi:10.1136/adc.2006.094649

    authors: Sinha Y,Silove N,Wheeler D,Williams K

    更新日期:2006-12-01 00:00:00

  • Antenatal and early infant predictors of postnatal growth in rural Vietnam: a prospective cohort study.

    abstract:OBJECTIVE:To determine which antenatal and early-life factors were associated with infant postnatal growth in a resource-poor setting in Vietnam. STUDY DESIGN:Prospective longitudinal study following infants (n=1046) born to women who had previously participated in a cluster randomised trial of micronutrient supplemen...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2014-306328

    authors: Hanieh S,Ha TT,De Livera AM,Simpson JA,Thuy TT,Khuong NC,Thoang DD,Tran TD,Tuan T,Fisher J,Biggs BA

    更新日期:2015-02-01 00:00:00

  • Neonatal urinary ascites.

    abstract::Two neonates with spontaneous rupture of the bladder and an otherwise normal genitourinary tract are described. Conservative management resulted in complete resolution of the lesion in one but the other child died from a coliform septicaemia. Necropsy showed a discrete ischaemic lesion in the fundus of the bladder. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.60.7.676

    authors: Morrell P,Coulthard MG,Hey EN

    更新日期:1985-07-01 00:00:00

  • IgG subclass specific antibody response in recurrent bronchitis.

    abstract::The IgG subclass specific immune response against pneumococcal type 3 polysaccharide antigen before and after immunisation in healthy children and children with recurrent bronchitis was studied. Recurrent bronchitis was defined as three or more episodes a year, during at least two consecutive years, of bronchopulmonar...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.66.12.1378

    authors: de Baets F,Pauwels R,Schramme I,Leroy J

    更新日期:1991-12-01 00:00:00

  • Use of external expiratory resistance in intubated neonates to increase lung volume.

    abstract::Ten intubated neonates (weights 0.90 to 2.58 kg) recovering from respiratory disease had lung mechanics, respiratory patterns, and functional residual capacity measured at 0 cmH2O continuous positive airways pressure and then after application of serially increasing levels of external expiratory resistance. At an exte...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.56.11.869

    authors: Moomjian AS,Schwartz JG,Shutack JG,Rooklin AR,Shaffer TH,Fox WW

    更新日期:1981-11-01 00:00:00

  • Reflection: moving from a mandatory ritual to meaningful professional development.

    abstract::Reflection has become established as a key principle underpinning maintenance of standards within professional education and practice. A requirement to evidence reflection within performance review is intended to develop a transformative approach to practice, identify developmental goals, and ultimately, improve healt...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,评审

    doi:10.1136/archdischild-2013-303948

    authors: Murdoch-Eaton D,Sandars J

    更新日期:2014-03-01 00:00:00

  • Monitoring of cerebral function after severe asphyxia in infancy.

    abstract::Thirty nine infants with severe asphyxia (28 affected perinatally and 11 later) were studied by electrophysiological cerebral function monitoring (CFM) for periods varying from a half to 49 days. Nineteen infants died while still in intensive care and two died later from sequelae. Eighteen survived and were followed u...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.58.12.997

    authors: Bjerre I,Hellström-Westas L,Rosén I,Svenningsen N

    更新日期:1983-12-01 00:00:00

  • Risk adjusted mortality of critical illness in a defined geographical region.

    abstract:AIMS:To evaluate the performance of the Paediatric Risk of Mortality (PRISM) score in a population of UK children and to use this score to examine severity of illness adjusted mortality of critically ill children <16 years old in a defined geographical region. METHODS:Observational study of a defined population of cri...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.86.3.194

    authors: Henderson AJ,Garland L,Warne S,Bailey L,Weir P,Edees S

    更新日期:2002-03-01 00:00:00

  • Epidemiological surveillance study of female genital mutilation in the UK.

    abstract:OBJECTIVES:Describe cases of female genital mutilation (FGM) presenting to consultant paediatricians and sexual assault referral centres (SARCs), including demographics, medical symptoms, examination findings and outcome. DESIGN:The well-established epidemiological surveillance study performed through the British Paed...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2020-319569

    authors: Hodes D,Ayadi O'Donnell N,Pall K,Leoni M,Lok W,Debelle G,Armitage AJ,Creighton SM,Lynn RM

    更新日期:2020-10-06 00:00:00

  • Patterns of long-term ADHD medication use in Australian children.

    abstract:OBJECTIVE:Adherence to attention-deficit/hyperactivity disorder (ADHD) medication treatment is often suboptimal. This can compromise patient outcomes. We aimed to describe the patterns of ADHD medication use in Australian children, and characteristics associated with patterns of use. DESIGN:Dispensing data were analys...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2019-317997

    authors: Efron D,Mulraney M,Sciberras E,Hiscock H,Hearps S,Coghill D

    更新日期:2020-06-01 00:00:00

  • Respiratory timing in intubated neonates with respiratory distress syndrome.

    abstract::Respiratory timing was studied in 100 babies ventilated for respiratory distress syndrome (RDS) during a brief period of continuous positive airway pressure. For the 76 spontaneously breathing babies the mean (SD) inspiratory and expiratory times were 0.31 (0.06) and 0.41 (0.12) seconds. Respiratory rate was predomina...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.67.4_spec_no.446

    authors: South M,Morley CJ

    更新日期:1992-04-01 00:00:00

  • Efficacy and safety of torasemide in children with heart failure.

    abstract:OBJECTIVE:To examine the efficacy and safety of torasemide in children with chronic heart failure (HF). METHODS:102 children with chronic HF who had received oral torasemide were analysed. Of these, 62 (de novo group) were newly diagnosed as having HF and were given torasemide as a diuretic. The remaining 40 (replacem...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.2007.129239

    authors: Senzaki H,Kamiyama M,Masutani S,Ishido H,Taketazu M,Kobayashi T,Katogi T,Kyo S

    更新日期:2008-09-01 00:00:00

  • The surviving monozygotic twin.

    abstract::It has been suggested that because of vascular interchange between the monozygous twins vascular disruptions from a deceased cotwin with disseminated intravascular coagulation causes embolisation in the surviving twin. This study reports six cases in which all the surviving monozygous twins had central nervous system ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.61.5.454

    authors: Szymonowicz W,Preston H,Yu VY

    更新日期:1986-05-01 00:00:00

  • Renal sodium handling in minimal change nephrotic syndrome.

    abstract::Renal sodium handling was studied in 23 children at three different stages of the minimal change nephrotic syndrome--the oedema forming state, proteinuric steady state, and remission. Clearances of inulin and para-aminohippuric acid and urinary sodium excretion were determined basally, after intravenous infusion of is...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.59.9.825

    authors: Bohlin AB,Berg U

    更新日期:1984-09-01 00:00:00

  • Problems of differentiation between epilepsy and non-epileptic paroxysmal events in the first year of life.

    abstract::Twenty two babies under 1 year old were referred for evaluation of suspected epileptic seizures. Nine were found to have epilepsy. In the other 13--all developing normally, aged up to 10 months--the spells were non-epileptic paroxysmal events (NEPE). They consisted of five patterns of movement: (1) eye blinking; (2) '...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.73.4.342

    authors: Shuper A,Mimouni M

    更新日期:1995-10-01 00:00:00

  • Pulmonary involvement with cytomegalovirus infections in children.

    abstract::Among 40 hospitalized infants and children with cytomegalovirus infection, 14 (35%) had interstitial pneumonitis, 4 (10%) had wheezing or tachypnoea but without x-ray evidence of classical interstitial pneumonia, the remaining 22 (55%) were free of pulmonary involvement. Most patients had tachypnoea and nonproductive ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.52.6.441

    authors: Smith SD,Cho CT,Brahmacupta N,Lenahan MF

    更新日期:1977-06-01 00:00:00

  • Sustained release theophylline in nocturnal asthma.

    abstract::Twice daily sustained release theophylline gave satisfactory steady serum theophylline concentrations in asthmatic children aged 7 to 14 years. The children showed improvement in symptoms, less frequent waking at night, reduced use of beta agonist inhalers, and improved early morning peak flows while being treated wit...

    journal_title:Archives of disease in childhood

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/adc.59.12.1159

    authors: Elias-Jones AC,Higenbottam TW,Barnes ND,Godden DJ

    更新日期:1984-12-01 00:00:00

  • Neuropathy in a petrol sniffer.

    abstract::A 4 year old boy developed a profound motor neuropathy after repeated deliberate inhalation of petroleum vapour. The condition was characterised by extreme slowing of the nerve conduction velocity. He made a gradual recovery over six months. The neuropathy was attributed to the N-hexane component of petroleum. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.61.9.900

    authors: Hall DM,Ramsey J,Schwartz MS,Dookun D

    更新日期:1986-09-01 00:00:00

  • Nutrition, sex, gestational age, and hair growth in babies.

    abstract::Hair growth measurements are a sensitive indicator of nutrition and we have assessed their value in the perinatal period. The proportion of growing roots and their diameter were studied at birth in 114 babies and repeated 3 weeks later in 29 low birthweight babies. Intrauterine malnutrition resulted in thinner roots b...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.53.4.290

    authors: Berger HM,King J,Doughty S,Wharton BA

    更新日期:1978-04-01 00:00:00