当前位置： SCI文献检索 > UROLOGY期刊下所有文献 > Preoperative parameters for predicting early prostate cancer recurrence after radical prostatectomy.

Preoperative parameters for predicting early prostate cancer recurrence after radical prostatectomy.

Abstract：

OBJECTIVES:To determine whether easily measurable prostate biopsy features could complement Gleason score, prostate-specific antigen (PSA), or clinical stage in predicting recurrence-free survival after prostatectomy. Information relating preoperative parameters to recurrence-free survival is needed to counsel patients with newly diagnosed prostate cancer regarding expectations for postprostatectomy cancer control. METHODS:The data of a cohort of 588 consecutive prostatectomy patients (median age 61 years, range 39 to 83) with ascertained preoperative data and up to 4 years of postprostatectomy follow-up were analyzed. Bivariate and multivariate Cox proportional hazards analysis evaluated preoperative factors (clinical stage, PSA, biopsy Gleason score, greatest percentage of a biopsy core involved by cancer [GPC], number of biopsy cores containing cancer, perineural invasion) to identify those relating significantly to recurrence-free survival. Functional forms of these factors were evaluated to optimize accuracy in predicting cancer control. RESULTS:The baseline parameters significantly affecting PSA-free survival included PSA level (P <0.01), biopsy Gleason score (P = 0.04), and GPC (P <0.01). Although clinical stage and perineural invasion had a marginal association with PSA-free survival as univariate factors, this association was not independently significant in multivariable analysis. The multivariate Cox model using PSA, Gleason score, and GPC was highly predictive of PSA free-survival (chi-square = 48.2, P = 0.0001). A set of plots representing these data can be used to identify the risk of early postoperative PSA recurrence on the basis of specific preoperative PSA, Gleason score, and GPC values. CONCLUSIONS:These findings provide a highly significant model and a simple tool for assisting preoperative patient counseling regarding predicted cancer control after radical prostatectomy.

journal_name

Urology

journal_title

Urology

authors

Nelson CP,Rubin MA,Strawderman M,Montie JE,Sanda MG

doi

10.1016/s0090-4295(02)01654-0

subject

Has Abstract

pub_date

2002-05-01 00:00:00

pages

740-5; discussion 745-6

issue

5

eissn

0090-4295

issn

1527-9995

pii

S0090429502016540

journal_volume

59

pub_type

杂志文章

相关文献

UROLOGY文献大全
  • Clinical phenotyping of patients with chronic prostatitis/chronic pelvic pain syndrome and correlation with symptom severity.

    abstract：OBJECTIVES:To propose a clinical phenotype system (urinary, psychosocial, organ specific, infection, neurologic/systemic, and tenderness [UPOINT]) to classify patients with urologic pelvic pain to help understand the etiology and guide therapy. We wished to validate this system in men with chronic pelvic pain syndrome ...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2008.09.074

    authors： Shoskes DA,Nickel JC,Dolinga R,Prots D

    更新日期：2009-03-01 00:00:00

  • Combination of Anandron with orchiectomy in treatment of metastatic prostate cancer. Results of a double-blind study.

    abstract：:A multicenter, randomized double-blind study was carried out in 203 patients with metastatic prostate cancer, in order to compare the efficacy of complete suppression of androgens achieved with surgical castration and nilutamide (Anandron), 100 mg t.i.d. The combined therapy was well-tolerated by patients, and they no...

    journal_title：Urology

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1016/0090-4295(91)80098-r

    authors： Beland G

    更新日期：1991-01-01 00:00:00

  • Endocrine status in elderly men with lower urinary tract symptoms: correlation of age, hormonal status, and lower urinary tract function. The Prostate Study Group of the Austrian Society of Urology.

    abstract：OBJECTIVES:To correlate endocrine parameters in elderly men with lower urinary tract symptoms (LUTS) to patient age and clinical parameters such as prostate volume, prostate-specific antigen (PSA) levels, and uroflowmetry and to compare the clinical and endocrinologic parameters in men with or without hypogonadism. ME...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/s0090-4295(99)00473-2

    authors： Schatzl G,Brössner C,Schmid S,Kugler W,Roehrich M,Treu T,Szalay A,Djavan B,Schmidbauer CP,Söregi S,Madersbacher S

    更新日期：2000-03-01 00:00:00

  • Microvascular surgery: adjunct to renal transplantation.

    abstract：:A new technique for microvascular anastomosis of the polar artery to the renal artery, end to side, is presented. It was performed in 5 cases of renal transplantation with a successful result in all. ...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/0090-4295(75)90808-0

    authors： Castro Ferreira M,Menezes de Góes G,Marmo Lucon A,Tedesco-Marchese A,Campos Freire G

    更新日期：1975-12-01 00:00:00

  • Retained Bullet in the Kidney: Imaging and Conservative Management.

    abstract：:Renal gunshot wounds resulting in a grade IV injury (AAST) should be explored only if they involve the hilum or if there are signs of suspected renal pelvis or ureteral laceration, active hemorrhage, peritonitis, or hemodynamically unstable patients (Kitrey et al, 2017).1 However, because of the paucity of cases repor...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2017.11.044

    authors： Mantica G,Kruger S,Ackermann H,Spies PV,Cassim F,Keyser Z,Terrone C,van der Merwe A

    更新日期：2018-03-01 00:00:00

  • Effect of early adrenal vein ligation on blood pressure and catecholeamine fluctuation during laparoscopic adrenalectomy for pheochromocytoma.

    abstract：OBJECTIVE:To define whether previous control of the adrenal vein is a crucial procedure in laparoscopic adrenalectomy for pheochromocytoma. METHODS:From January 2000 to December 2010, 114 patients with pheochromocytoma who underwent laparoscopic adrenalectomy through transperitoneal or retroperitoneal approach were in...

    journal_title：Urology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.urology.2013.05.011

    authors： Wu G,Zhang B,Yu C,Gao L,Gao Y,Huang Y,Yu L,Zhang G,Yang L,Yuan J

    更新日期：2013-09-01 00:00:00

  • Performance Optimization Strategies for Complex Endourologic Procedures.

    abstract：OBJECTIVE:To identify and address factors that may impact a surgeon's performance during endourologic procedures. METHODS:A literature review was performed for articles focusing on surgical ergonomics, education, sports and performance psychology. RESULTS:As urologists and trainees have become more comfortable approa...

    journal_title：Urology

    pub_type： 杂志文章,评审

    doi：10.1016/j.urology.2020.01.033

    authors： Golan R,Shah O

    更新日期：2020-05-01 00:00:00

  • Executive Summary of the National Cancer Institute Workshop: Highlights and recommendations.

    abstract：:Prostate cancer chemoprevention represents a relatively new and promising strategy for reducing the immense public health burden of this devastating cancer of men in the United States and Western societies. Chemoprevention is defined as the administration of agents (drugs, biologics, and natural products) that modulat...

    journal_title：Urology

    pub_type：

    doi：10.1016/s0090-4295(00)00931-6

    authors： Lieberman R,Nelson WG,Sakr WA,Meyskens FL Jr,Klein EA,Wilding G,Partin AW,Lee JJ,Lippman SM

    更新日期：2001-04-01 00:00:00

  • Posterior Urethroplasty Complexity and Prognosis Can be Described by a Novel Method: Posterior Urethral Stenosis Score.

    abstract：OBJECTIVE:To develop a standardized PU-score (posterior urethral stenosis score), with the goal of using this scoring system as a preliminary predictor of surgical complexity and prognosis of posterior urethral stenosis. PATIENTS AND METHODS:We retrospectively reviewed records of all patients who underwent posterior u...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2017.09.004

    authors： Wang L,Lv X,Jin C,Guo H,Shu H,Fu Q,Sa Y

    更新日期：2018-02-01 00:00:00

  • Should function and bother be measured and reported separately for prostate cancer quality-of-life domains?

    abstract：OBJECTIVES:To evaluate the psychometric properties of the three domains bowel, urinary, and sexual function as they were measured in the Prostate Cancer Outcomes Study and examine their use in different research and practice settings. Leading prostate cancer health-related quality-of-life questionnaires include questio...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2006.03.037

    authors： Reeve BB,Potosky AL,Willis GB

    更新日期：2006-09-01 00:00:00

  • Impact of preoperative ureteral stenting on stone-free rates of ureteroscopy for nephroureterolithiasis: a matched-paired analysis of 286 patients.

    abstract：OBJECTIVE:To determine the effect of preoperative ureteral stenting on success rates of ureteroscopy (URS) for nephroureterolithiasis. MATERIALS AND METHODS:We retrospectively evaluated patients who underwent URS for nephroureterolithiasis without preoperative indwelling ureteral stents. These patients were matched ac...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2012.06.064

    authors： Netsch C,Knipper S,Bach T,Herrmann TR,Gross AJ

    更新日期：2012-12-01 00:00:00

  • Evaluation of Vasectomy Trends in the United States.

    abstract：OBJECTIVE:To use the Truven Health MarketScan database to better approximate the annual rate of vasectomies performed in the US population, to determine changes over time, regional differences, providers performing this, and to know if there is any monthly variation in vasectomy rates. MATERIALS AND METHODS:Claims dat...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2018.03.016

    authors： Ostrowski KA,Holt SK,Haynes B,Davies BJ,Fuchs EF,Walsh TJ

    更新日期：2018-08-01 00:00:00

  • Ochronosis of prostate presenting as advanced carcinoma.

    abstract：:Ochronosis is the clinical manifestation of alkaptonuria, a rare inborn error of metabolism. It is characterized by widespread pigmentation of the fibroconnective tissues, arthritis, and passage of dark urine. Prostatic involvement is usually limited to the incidental finding of calculi within the gland. Herein, we re...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/0090-4295(83)90502-2

    authors： Suarex GM,Roberts JA

    更新日期：1983-08-01 00:00:00

  • Urinary diversion in patients with spinal cord injury in the United States.

    abstract：OBJECTIVE:To describe the patterns in the use of bladder augmentation and urinary diversion to manage urologic sequelae among patients with spinal cord injury in the United States. MATERIALS AND METHODS:Discharge estimates were derived from the Nationwide Inpatient Sample. All patients underwent bladder augmentation o...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2012.06.063

    authors： Peterson AC,Curtis LH,Shea AM,Borawski KM,Schulman KA,Scales CD Jr

    更新日期：2012-12-01 00:00:00

  • Extraperitoneal ureterocystoplasty with transureteroureterostomy.

    abstract：:Ureterocystoplasty enables the bladder to be reliably enlarged and the resultant neobladder to be lined by urothelium. Many techniques have been described for the operative management of the lower ureter, and a number of alternatives have been suggested for reconstruction of the upper renal tract and bladder. This rep...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/s0090-4295(98)00363-x

    authors： Dewan PA,Condron SK

    更新日期：1999-03-01 00:00:00

  • Amplatz sheath for cystolithotripsy using Ho: YAG laser in female patients.

    abstract：OBJECTIVE:To evaluate the effectiveness of cystoscopic lithotripsy, we performed Amplatz sheath technique using Ho: YAG laser. Maheshwari first reported the use of an Amplatz sheath in the female urethra in 1998, and Okeke et al reported the use of an Amplatz sheath for male patients during cystolithotripsy in 2004. Th...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2012.07.046

    authors： Kawahara T,Ito H,Terao H,Kato Y,Ogawa T,Uemura H,Kubota Y,Matsuzaki J

    更新日期：2012-11-01 00:00:00

  • Failed posterior urethroplasty: lessons learned.

    abstract：OBJECTIVES:To determine the factors contributing to unsuccessful results after posterior urethroplasty and to establish some guidelines for its prevention. METHODS:From 1977 through 2000, 130 patients (3 to 58 years old) underwent 145 anastomotic urethroplasty procedures for post-traumatic posterior urethral distracti...

    journal_title：Urology

    pub_type： 杂志文章,评审

    doi：10.1016/s0090-4295(03)00573-9

    authors： Koraitim MM

    更新日期：2003-10-01 00:00:00

  • Medical testosterone: an iatrogenic cause of male infertility and a growing problem.

    abstract：OBJECTIVE:To determine (1) the frequency of testosterone (T) use in 2 academic male infertility practices, (2) the effect on semen parameters, and (3) the potential for reversibility. METHODS:We performed a retrospective review. Inclusion criteria were supplemental T usage at the time of initial visit, T cessation, an...

    journal_title：Urology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.urology.2014.12.052

    authors： Kolettis PN,Purcell ML,Parker W,Poston T,Nangia AK

    更新日期：2015-05-01 00:00:00

  • Measurement of the proportion of free to total prostate-specific antigen improves diagnostic performance of prostate-specific antigen in the diagnostic gray zone of total prostate-specific antigen.

    abstract：OBJECTIVES:This study examined the clinical significance of non-complexed (free) prostate-specific antigen (PSA) in the differential diagnosis of prostate cancer with an emphasis on patients with total PSA values between 4.0 and 10.0 ng/mL (the diagnostic gray zone). METHODS:Serum samples were obtained from three spec...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/s0090-4295(99)80192-7

    authors： Luderer AA,Chen YT,Soriano TF,Kramp WJ,Carlson G,Cuny C,Sharp T,Smith W,Petteway J,Brawer MK

    更新日期：1995-08-01 00:00:00

  • Pelvic lipomatosis.

    abstract：:Three cases of pelvic lipomatosis are presented. Excretory urogram revealed characteristic elevation and elongation of urinary bladder base and relative hyperlucency of pelvic cavity. Associated varying degrees of hydronephrosis and hydroureters are seen secondary to distal ureteral obstruction. Barium enema showed el...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/0090-4295(76)90578-1

    authors： Radinsky S,Cabal E,Shields J

    更新日期：1976-01-01 00:00:00

  • Multiple, Synchronous Lesions of Differing Histology Within the Same Testis: Ultrasonographic and Pathologic Correlations.

    abstract：OBJECTIVE:To describe ultrasound (US) and pathologic findings in 11 patients with multiple, synchronous lesions of different histology within the same testis. MATERIALS AND METHODS:We reviewed US and pathologic findings in 11 patients with multiple, synchronous lesions of different histology within the same testis. Le...

    journal_title：Urology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.urology.2018.07.040

    authors： Cicero C,Bertolotto M,Hawthorn BR,Trambaiolo Antonelli C,Sidhu PS,Ascenti G,Nikolaidis P,Dudea S,Toncini C,Derchi LE

    更新日期：2018-11-01 00:00:00

  • Multifocal penile epithelioid hemangioendothelioma masquerading as superficial penile vein thrombosis.

    abstract：:A 42-year-old man presented with a progressively painful mass of the penile shaft that clinically resembled superficial penile vein thrombosis. The patient's symptoms were refractory to conservative therapy, and surgical excision revealed multifocal penile epithelioid hemangioendothelioma. He had no evidence of metast...

    journal_title：Urology

    pub_type： 杂志文章,评审

    doi：10.1016/j.urology.2006.03.051

    authors： Gharajeh A,Siemens DR,Isotalo PA,Nascimento AG,Borth CS

    更新日期：2006-09-01 00:00:00

  • Functional Restoration of Erectile Function Using End-to-side Autonomic-to-somatic Neurorrhaphy in Rats.

    abstract：OBJECTIVE:To investigate the feasibility of erectile function rehabilitation using end-to-side autonomic-to-somatic neurorrhaphy in rats. MATERIALS AND METHODS:Thirty-six adult male Sprague-Dawley rats were divided into 3 groups (n = 12 per group): in the end-to-side coaptation group, the left L6 and S1 spinal nerves ...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2016.05.017

    authors： Dong C,Dong Z,Xie Z,Zhang L,Xiong F,Wen Q,Fan Z,Peng Q

    更新日期：2016-09-01 00:00:00

  • A 12-year experience with enterovesical fistulas.

    abstract：OBJECTIVES:To review our experience with enterovesical fistulas in order to determine the most accurate diagnostic studies and most effective method of treatment. METHODS:A retrospective record review of 76 patients who were diagnosed and treated for enterovesical fistulas over a 12-year period was performed. Data col...

    journal_title：Urology

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0090-4295(94)80200-9

    authors： McBeath RB,Schiff M Jr,Allen V,Bottaccini MR,Miller JI,Ehreth JT

    更新日期：1994-11-01 00:00:00

  • Role of lymphadenectomy in the treatment of renal cell carcinoma.

    abstract：:We evaluated the role of lymphadenectomy (LND) in the prevention of local recurrence following radical nephrectomy for renal cell carcinoma (RCC) by two retrospective studies. In one, the relative importance of various tumor characteristics to the subsequent development of local recurrence was investigated in 37 patie...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/0090-4295(93)90234-2

    authors： Phillips E,Messing EM

    更新日期：1993-01-01 00:00:00

  • Testicular seminoma originating in an undescended testis in a renal allograft recipient.

    abstract：:Immunosuppressed transplant recipients are at significantly increased risk for developing neoplasms than are nonimmunosuppressed individuals. However, only six cases of pure testicular seminoma following renal transplantation have been reported in the English literature. This case report represents the first descripti...

    journal_title：Urology

    pub_type： 杂志文章,评审

    doi：10.1016/s0090-4295(96)00104-5

    authors： Modlin CS,Flechner SM,Penn I

    更新日期：1996-07-01 00:00:00

  • Incidence of upper tract abnormalities in patients with neurovesical dysfunction secondary to multiple sclerosis: analysis of risk factors at initial urologic evaluation.

    abstract：OBJECTIVES:To determine the incidence of upper tract abnormalities on renal ultrasonography in patients with multiple sclerosis (MS) referred for urologic evaluation, as well as to identify any risk factors present on the basis of the historical information and urodynamic findings. METHODS:Data were derived from all p...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2004.11.038

    authors： Lemack GE,Hawker K,Frohman E

    更新日期：2005-05-01 00:00:00

  • Postoperative care following internal urethrotomy.

    abstract：:A randomized prospective study was set up to assess the role of postoperative catheter drainage and the value of hydraulic self-dilatation of the urethra after internal urethrotomy. Sixty-two patients were admitted into the study and followed-up for two years. The results support the use of a no-catheter posturethroto...

    journal_title：Urology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0090-4295(85)90178-5

    authors： Kaisary AV

    更新日期：1985-10-01 00:00:00

  • Long-term results of antegrade endoureterotomy using the holmium laser in patients with ureterointestinal strictures.

    abstract：OBJECTIVES:To investigate the effectiveness and morbidity of percutaneous laser endoureterotomy in the management of ureterointestinal anastomotic strictures after radical cystectomy and urinary diversion. METHODS:Between May 1997 and August 2000, 19 percutaneous endoureterotomy incisions, including 3 repeated incisio...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/s0090-4295(01)01396-6

    authors： Laven BA,O'Connor RC,Steinberg GD,Gerber GS

    更新日期：2001-12-01 00:00:00

  • Metastatic intratesticular alveolar rhabdomyosarcoma discovered after induction of systemic chemotherapy.

    abstract：:Alveolar rhabdomyosarcoma is an aggressive cancer that can metastasize to a variety of organs. We present what we believe to be the first reported case of metastatic intratesticular rhabdomyosarcoma in a patient presenting with testicular pain shortly after the induction of systemic chemotherapy. The published data re...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2007.02.023

    authors： Cannon GM Jr,Polsky EG,Bellinger MF

    更新日期：2007-05-01 00:00:00