Abstract:
:A multicenter, randomized double-blind study was carried out in 203 patients with metastatic prostate cancer, in order to compare the efficacy of complete suppression of androgens achieved with surgical castration and nilutamide (Anandron), 100 mg t.i.d. The combined therapy was well-tolerated by patients, and they noted a better relief of bone pain after six months than those in the control group. There was a greater number of favorable responses in the combined treatment group. In addition, despite a similar median progression-free actuarial rate, the combined treatment (nilutamide plus orchiectomy) offered an improved survival time over orchiectomy alone.
journal_name
Urologyjournal_title
Urologyauthors
Beland Gdoi
10.1016/0090-4295(91)80098-rsubject
Has Abstractpub_date
1991-01-01 00:00:00pages
25-9issue
2 Suppleissn
0090-4295issn
1527-9995journal_volume
37pub_type
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