Abstract：
:Recent advances in the understanding of the pathogenesis, behavior, and molecular biology of renal cell carcinoma (RCC) have paved the way for developments that may enhance early diagnosis, better predict prognosis, and improve survival. Reliable predictive factors are essential for the stratification of patients into clinically meaningful categories that can be used to provide patients with counseling regarding prognosis, select treatment modalities, and determine eligibility for clinical trials. The TNM (tumor, nodes, metastasis) staging system is currently the most extensively used staging system for RCC, but it has undergone systematic revisions as a result of emerging data. Comprehensive integrated staging systems that combine important clinical and pathological variables have been created in an attempt to improve prognostication. Although staging has improved with the development of integrated systems, the incorporation of molecular tumor markers are expected to revolutionize the staging of RCC. This article reviews the important molecular markers in RCC to date and discusses their role in the diagnosis, prognostication, and therapy of patients with RCC.
journal_name
Urologyjournal_title
Urologyauthors
Lam JS,Leppert JT,Figlin RA,Belldegrun ASdoi
10.1016/j.urology.2005.06.112subject
Has Abstractpub_date
2005-11-01 00:00:00pages
1-9issue
5 Suppleissn
0090-4295issn
1527-9995pii
S0090-4295(05)00969-6journal_volume
66pub_type
杂志文章,评审相关文献
UROLOGY文献大全abstract：OBJECTIVE:To evaluate the relationship of the glomerular filtration rate (GFR) and lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia measures in middle-aged men. METHODS:A total of 1400 male police officers with moderate and severe LUTS (international prostate symptoms score [IPSS] >7) and aged 40-59 ye...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2013.07.049
更新日期：2013-12-01 00:00:00
abstract：OBJECTIVE:To evaluate the correlation between ultrasonography (US) and computed tomography (CT) in prone position to detect retrorenal colon (RRC). MATERIALS AND METHODS:In this prospective study, we included 310 patients who presented to our clinic between April 2017 and June 2019. All patients were evaluated for RRC...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2020.07.016
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVE:To assess clinical safety (primary) and efficacy (secondary) of histotripsy for treatment of symptomatic benign prostatic enlargement in a first-in human study. METHODS:Twenty-five male subjects with moderate to severe lower urinary tract symptoms, prostate size between 30 and 80 g, and no evidence of prosta...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2017.12.033
更新日期：2018-04-01 00:00:00
abstract：:Inflammatory pseudotumor of the bladder is a rare benign lesion of unknown etiology. We present a new case of pseudotumor of the urachus in a 16-year-old boy with no significant urologic history. This benign condition mimics invasive malignant tumors of the urinary bladder, and aggressive surgery is the basic treatmen...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2005.09.044
更新日期：2006-03-01 00:00:00
abstract：:Urinary incontinence in pediatric and adolescent patients has been successfully managed with the artificial urinary sphincter for several decades. Placement of the sphincter can be difficult in the preadolescent girl due to poorly developed vaginal tissue that can result in difficulty establishing the surgical plane b...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(99)00277-0
更新日期：1999-11-01 00:00:00
abstract：:In an attempt to solve the problem of chemosensitivity testing of renal cell carcinoma in vitro, a modified short-term culture technique was developed. The kinetic study of hypernephroma cells and normal renal cells showed that the uptake of H3-uridine and H3-thymidine is at its maximum after eighty hours. The effect ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(88)90150-1
更新日期：1988-03-01 00:00:00
abstract：OBJECTIVES:To compare outcomes of radical retropubic, laparoscopic, and robotic-assisted prostatectomy using evidence-based analysis. METHODS:We performed meta-analysis of observational studies directly comparing radical retropubic, laparoscopic, and robotic-assisted prostatectomy for the treatment of localized prosta...
journal_title：Urology
pub_type： 杂志文章,meta分析
doi：10.1016/j.urology.2007.11.026
更新日期：2008-08-01 00:00:00
abstract：:Peyronie's disease (PD) is a penile wound-healing disorder resulting in fibrotic plaque in the tunica albuginea, likely resulting from micro trauma. Due to variable disease presentations, a myriad of proposed treatment options, physician misconceptions about the disorder, and severe psychological distress in afflicted...
journal_title：Urology
pub_type： 杂志文章,评审
doi：10.1016/j.urology.2016.02.009
更新日期：2016-09-01 00:00:00
abstract：:Using the Dornier HM-3 lithotriptor, 10 patients (11 renal units) with calculi in horseshoe kidneys were treated with extracorporeal shock-wave lithotripsy (ESWL) and ancillary procedures. Six renal units (55%) underwent pre-ESWL manipulation consisting of a Double J stent, ureteral catheter, or percutaneous nephrosto...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(90)80082-x
更新日期：1990-05-01 00:00:00
abstract：:Between August 1991 and July 1994, an original balloon-expanding urethral suture guide (24 F) was used in 157 consecutive cases of radical retropubic prostatectomy. Both the instrument and its clinical use are described. This guide guarantees good intraoperative exposure of the sectioned urethral stump during vesical ...
journal_title：Urology
pub_type： 临床试验,杂志文章
doi：10.1016/s0090-4295(99)80274-x
更新日期：1995-10-01 00:00:00
abstract：OBJECTIVE:To assess (1) plasma levels of antidiuretic hormone (ADH) and brain natriuretic peptide (BNP) and urinary levels of electrolytes in children with sleep disordered breathing (SDB), with or without nocturnal enuresis (NE), and (2) the effect of adenotonsillectomy (T&A) on urinary electrolytes and the secretion ...
journal_title：Urology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.urology.2015.04.011
更新日期：2015-07-01 00:00:00
abstract：OBJECTIVE:To use the tuberous sclerosis complex (TSC) Natural History Database to describe monitoring and treatment patterns among patients with TSC-related angiomyolipomas (AMLs). METHODS:This study used the TSC Natural History Database, which contains demographics, affected areas, diagnosis, and treatments for more ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2017.02.036
更新日期：2017-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the association of male lower urinary tract symptoms (LUTS) with metabolic syndrome (MetS) and androgenetic alopecia in a Latin American population. METHODS:We enrolled 907 patients for prospective evaluation at a single institution. LUTS were evaluated with the International Prostate Symptom Sco...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2013.03.001
更新日期：2013-07-01 00:00:00
abstract：:We report a case of a critically ill patient who had a ureterocutaneous fistula develop after placement of a Dacron bypass graft from the aorta to the right popliteal artery and the left femoral artery. We describe a successful nonsurgical method to terminate renal function in this patient, who was a poor operative ri...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(79)90295-4
更新日期：1979-02-01 00:00:00
abstract：:A contracted empty scrotum in a young man will not accept an artificial testis satisfactorily using any of the standard techniques. Previous operative scars, as from a failed orchiopexy, have often added to the difficulties. Greatly enlarging the scrotum by gradual distention of a tissue expander implanted in the cont...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(89)90056-3
更新日期：1989-01-01 00:00:00
abstract：:Turner syndrome is a chromosomal disorder that occurs in an estimated 1 in 2500 female live births. It is estimated that 6%-12% of all Turner syndrome patients will be a mosaic with Y-chromosomal elements putting them at risk for gonadoblastoma and subsequent dysgerminoma. While 30%-50% of this population demonstrate ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2020.01.031
更新日期：2020-05-01 00:00:00
abstract：:To plan the treatment of carcinoma of the bladder correctly accurate knowledge of the morphology and degree of infiltration of the tumor is essential. Double contrast cystography and polycystography are radiologic techniques that can provide such information. Hitherto, these two procedures have been performed separate...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(77)90201-1
更新日期：1977-02-01 00:00:00
abstract：OBJECTIVES:To assess the clinical efficacy of neodymium:yttrium-aluminum-garnet (YAG) laser coagulation prostatectomy using a broad-angle, divergent-beam, side-firing fiber. METHODS:Eighty adult men with voiding symptoms caused by benign prostatic hyperplasia were enrolled in a prospective multicenter study of free-be...
journal_title：Urology
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1016/S0090-4295(97)00117-9
更新日期：1997-07-01 00:00:00
abstract：OBJECTIVE:To review the robustness of hydronephrosis literature with the application of fragility index (FI) and fragility quotient (FQ) calculations. METHODS:A literature review was conducted using Pubmed, Medline, and Ovid for "hydronephrosis" and associated terms and we included all studies with at least 2 groups b...
journal_title：Urology
pub_type： 杂志文章,评审
doi：10.1016/j.urology.2019.03.045
更新日期：2019-11-01 00:00:00
abstract：:Recently, a flexible, self-expanding, permanent endoprosthesis has been developed to maintain patency of stenotic arteries after balloon angioplasty. This device, known as the UroLume Wallstent, is now under active investigation in both Europe and the United States as a treatment for: (1) recurrent bulbar urethral str...
journal_title：Urology
pub_type： 杂志文章,评审
doi：10.1016/0090-4295(93)90189-h
更新日期：1993-01-01 00:00:00
abstract：OBJECTIVES:To evaluate whether the relationship between sexual desire and quality of life (QOL) is moderated by sexual functioning in 91 men who had received treatment for localized prostate cancer within the past 18 months. METHODS:Items from the University of California, Los Angeles, Prostate Cancer Index and Expand...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2003.09.048
更新日期：2004-02-01 00:00:00
abstract：OBJECTIVES:To examine the rate of biochemical recurrence (BCR) in patients with pathologically confirmed insignificant prostate cancer (PIPCa). METHODS:A total of 1358 patients underwent open retropubic radical prostatectomy at the University Medical Center Eppendorf in Hamburg, Germany, and their specimens were whole...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2008.04.053
更新日期：2008-12-01 00:00:00
abstract：:A ureteroscopy for stone removal resulted in a tear of the ureter and extensive necrosis requiring ureteroneocystostomy. Urologists are urged to report complications of upper tract endoscopy and to apprise patients of the inherent dangers. ...
journal_title：Urology
pub_type： 杂志文章
doi：
更新日期：1984-03-01 00:00:00
abstract：:The surgical riks were analyzed in 305 patients with end stage renal failure who underwent bilateral nephrectomy through midabdominal approach in preparation for kidney transplantation. The over-all mortality rate was 3.6 per cent. Age was the most significant risk factor in the mortality. Patients less than fifty yea...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(78)90367-9
更新日期：1978-07-01 00:00:00
abstract：OBJECTIVES:To investigate a link between the appearance of photoacoustic imaging (PAI) and microvasculature in prostate cancer and to assess the feasibility of PAI for angiogenesis imaging in prostate cancer. METHODS:We have developed a PAI system equipped with a transrectal ultrasound (TRUS)-type probe. Three patient...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2017.07.008
更新日期：2017-10-01 00:00:00
abstract：:Extragonadal germ cell tumors are a rare clinical entity. We present the case of an extragonadal germ cell tumor followed by testicular recurrence more than 4 years later. This presents an interesting dilemma as to whether this was recurrence of the original tumor or a new, primary tumor. The patient's outcome and sur...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2004.06.016
更新日期：2004-11-01 00:00:00
abstract：OBJECTIVE:Despite many known advantages, the radical perineal prostatectomy (RPP) had fallen out of favor because of the need for a second incision for the regional lymph node dissection. Laparoscopic lymphadenectomy, however, provides an accurate and minimally invasive alternative to open lymph node dissection. Herein...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(94)90238-0
更新日期：1994-04-01 00:00:00
abstract：:Bladder neck contracture after antegrade fulguration of posterior urethral valves has not been reported in English studies to date to the best of our knowledge. A couple of reports have mentioned late-onset bladder neck contracture after retrograde valve fulguration. The present case report describes an unusual compli...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2008.07.071
更新日期：2009-04-01 00:00:00
abstract：OBJECTIVE:To evaluate kidney function preservation or regeneration and pathological changes post-irreversible electroporation (IRE) in comparison with partial nephrectomy and radiofrequency ablation (RFA) in a solitary kidney porcine model. Tissue ablation using IRE has been reported to spare critical anatomic structur...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2016.04.035
更新日期：2016-08-01 00:00:00
abstract：:A left vein varicocele was created in male dogs by partially obstructing the left renal vein medial to the entrance of the left internal spermatic vein. Eight dogs had semen parameters determined preoperatively (2 times/week for five weeks) and postoperatively (2 times/week for twelve weeks). Semen quality was altered...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(79)90466-7
更新日期：1979-05-01 00:00:00
