Abstract:
:Two cases are reported of combined renal and hepatic failure following exposure to halothane anesthesia. Both patients presented with postoperative fever and rapidly deteriorating liver and kidney function. Both required peritoneal dialysis. Both patients died, and in both cases this was the second exposure to halothane. The pathologic features of the 2 cases were similar in that the liver changes were typical of those seen with halothane hepatitis and the renal lesion was similar to that of methoxyflurane nephritis. This is, to our knowledge, the third report of renal failure occurring after halothane anesthesia. Possible mechanisms regarding its toxicity are discussed.
journal_name
Urologyjournal_title
Urologyauthors
Gelman ML,Lichtenstein NSdoi
10.1016/0090-4295(81)90255-7subject
Has Abstractpub_date
1981-04-01 00:00:00pages
323-7issue
4eissn
0090-4295issn
1527-9995pii
0090-4295(81)90255-7journal_volume
17pub_type
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