Abstract：
OBJECTIVE:To describe ultrasound (US) and pathologic findings in 11 patients with multiple, synchronous lesions of different histology within the same testis. MATERIALS AND METHODS:We reviewed US and pathologic findings in 11 patients with multiple, synchronous lesions of different histology within the same testis. Lesions were classified as separate or adjacent one to another and attempt was made to predict tumor type on their US textures. Pathologic review assessed presence of normal tissue between adjacent lesions and of Germ Cell Neoplasia In Situ in surrounding parenchyma. Nine cases were from files specifically dedicated to testicular tumors and estimated prevalence was calculated. RESULTS:Two nodules were seen in nine patients and 3 in remaining two. Nine had tumors of different histology; two had one malignancy and one focal benign lesion. Germ Cell Neoplasia In Situ was seen in 7/11 cases. In dedicated archives, these lesions had 1.83% prevalence. CONCLUSION:Multiple focal lesions identified at imaging within the testis are not always of the same histology. This can be suspected in some cases basing on US texture. Recognition that lesions are multiple and an indication of their locations within the testis is the most important role of imaging and may help pathologists correctly sample the specimen to establish nature of each of them. Presence of multiple lesions is regarded as a contraindication to testicular sparing surgery. In two of our patients, one lesion was benign. Then, when the procedure is indicated all lesions have to be sampled and assessed by pathologists before deciding between conservative or radical technique.
journal_name
Urologyjournal_title
Urologyauthors
Cicero C,Bertolotto M,Hawthorn BR,Trambaiolo Antonelli C,Sidhu PS,Ascenti G,Nikolaidis P,Dudea S,Toncini C,Derchi LEdoi
10.1016/j.urology.2018.07.040subject
Has Abstractpub_date
2018-11-01 00:00:00pages
125-131eissn
0090-4295issn
1527-9995pii
S0090-4295(18)30807-0journal_volume
121pub_type
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