Prognostic significance of nodal involvement in locally advanced (stage C) carcinoma of prostate--RTOG experience.

Abstract:

:A total of 500 patients with extracapsular extension (clinical Stage C) carcinoma of the prostate received definitive radiotherapy directed to the prostate and the regional lymphatics. Pretreatment evaluation of the regional lymphatics was optional and was done in 245 patients who underwent either staging laparotomy or lymphangiography. The remaining 255 patients had no nodal evaluation. In 72 of the node-evaluated patients there was evidence of spread to the pelvic lymphatics and in 173 patients lymph nodes were negative. The three populations (lymph nodes-not evaluated, lymph nodes-involved, and lymph nodes-not involved) were analyzed as to the distribution of the recognized prognostic variables and compared as to the study end points (locoregional failure, incidence of distant metastases, disease-free survival, and survival).

journal_name

Urology

journal_title

Urology

authors

Pilepich MV,Johnson RJ,Perez CA,Krall JM,Russ HH,Zinninger M,Sause WT,Hanks GE,Martz KL

doi

10.1016/0090-4295(87)90431-6

subject

Has Abstract

pub_date

1987-12-01 00:00:00

pages

535-40

issue

6

eissn

0090-4295

issn

1527-9995

pii

0090-4295(87)90431-6

journal_volume

30

pub_type

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