Abstract:
:Studies published from January 1966 until October 2000 on the clinical effects of focal neuronal and neuromuscular blockade in post stroke upper limb spasticity were identified. Twelve studies were included and evaluated on 13 methodological criteria. Ten studies on Botulinum toxin type A (BTX-A) treatment were found (of which 4 were randomised controlled trials (RCTs) and 6 were uncontrolled observational studies) as well as one uncontrolled observational study on phenol blockade of the subscapular muscle and one on alcohol blockade of the musculocutaneus nerve. The homogeneity of the patient groups with regard to diagnosis and their comparability with regard to functional prognosis and other sources of bias were generally unsatisfactory. Only two RCTs met predetermined criteria of minimal validity. There is evidence of effectiveness of BTX-A treatment on reducing muscle tone (varying between 0.8 and 2.0 points on the modified Ashworth scale) and improving passive range of motion at all arm-hand levels in chronic stroke patients for approximately 3-4 months. There is also preliminary evidence of a synergistic effect of concomitant electrostimulation. Taking into account a critical maximum dose of 100 MU Botox" (300-500 MU Dysport) for preserving active finger flexion, BTX-A treatment seems to be a safe focal spasmolytic treatment. Effectiveness of BTX-A treatment on improving functional abilities could not be convincingly demonstrated, although two subgroups may be identified that might specifically benefit at a functional level: (1) patients with mild spasticity and a potential for voluntary extensor activity and (2) patients with severe spasticity suffering from problems with positioning and taking care of the affected arm and hand. Larger controlled studies are needed to compare the effectiveness of BTX-A with other focal spasmolytic techniques paying special attention to individual goal assessment, the (duration of) functional benefits, co-treatment and aftercare, side-effects and cost-effectiveness.
journal_name
J Rehabil Medjournal_title
Journal of rehabilitation medicineauthors
van Kuijk AA,Geurts AC,Bevaart BJ,van Limbeek Jdoi
10.1080/165019702753557836subject
Has Abstractpub_date
2002-03-01 00:00:00pages
51-61issue
2eissn
1650-1977issn
1651-2081journal_volume
34pub_type
杂志文章,评审abstract:OBJECTIVE:To identify predictive factors for work capacity in patients with musculoskeletal disorders. DESIGN:A descriptive, evaluative, quantitative study. SUBJECTS/PATIENTS:The study was based on 385 patients who participated in a rehabilitation programme. METHODS:Patients were divided into 2 groups depending on t...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.1080/16501970510030255
更新日期:2005-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the test-retest reliability of isometric and isokinetic muscle strength measurements in the upper extremity after stroke. DESIGN:A test-retest design. SUBJECTS:Forty-five persons with mild to moderate paresis in the upper extremity > 6 months post-stroke. METHODS:Isometric arm strength (shoulde...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-1990
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:To determine reliability of maximal grip strength, muscle coordination and muscle endurance. To compare these parameters in young adults with unilateral cerebral palsy and healthy subjects. To evaluate the correlation of these variables with functional activities. SUBJECTS:Twenty-six healthy subjects and 26 ...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-0095
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVE:To investigate costs and quality-adjusted life years of rehabilitation combined with abobotulinumtoxinA (aboBoNT-A) (rehab/aboBoNT-A) vs rehabilitation alone (rehab) in post-stroke spasticity in Italy. DESIGN:Based on both Italian National Health Service and societal perspectives, a 2-year cost-utility analy...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-2636
更新日期:2020-02-07 00:00:00
abstract:OBJECTIVE:To examine the metric properties of the Utrecht Scale for Evaluation of Rehabilitation-Participation (USER-Participation) in persons with spinal cord injury in Switzerland from a classical and item response theory perspective. DESIGN:Cross-sectional survey. SUBJECTS:Persons with spinal cord injury living in...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-2010
更新日期:2016-02-01 00:00:00
abstract::Refugees have often been exposed to torture in their countries of origin. A core issue is the resulting multifaceted presentation of somatic, psychological and social problems in the same individual, leading to severe activity limitations and participation restrictions. An international conference, "Rehabilitating Tor...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-0426
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:It is important for older adults to be physically active, but many older adults walk slowly. This study examined the accuracy of a commercially available step-count device (Fitbit One) at slow speeds and compared the accuracy of the device when worn at the ankle and waist in older adults. METHODS:The Fitbit ...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-1993
更新日期:2015-10-05 00:00:00
abstract:OBJECTIVE:Sex-specific medicine requires understanding of the specific therapeutic needs and patho-physiology of men and women. In these terms, we investigated sex-related differences in the gait kinematics of patients with Down syndrome. DESIGN:Retrospective observational cohort study. SUBJECTS:A sample of 230 patie...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-2507
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:To evaluate inpatient rehabilitation in public facilities in Australia against a utilization review tool used in the USA. DESIGN:Prospective cohort study. SUBJECTS:Patients identified in the acute wards of a regional referral hospital and subsequently transferred to a public inpatient rehabilitation facilit...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-0506
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVE:To compare individual, group and combined intervention formats for improving goal attainment and psychosocial function following acquired brain injury. DESIGN:Randomized controlled trial, waiting list controls. PARTICIPANTS:Thirty-five participants with a mean time of 5.29 years (standard deviation = 3.9) s...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章,随机对照试验
doi:10.2340/16501977-0124
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVE:Inter-organizational coordination is important for rehabilitation disaster relief. The 2011 Great East Japan Earthquake and Disaster was unprecedented, being geographically widespread and multifaceted. Faced with the crisis, rehabilitation professionals established the 10 Rehabilitation-Related Organizations ...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-0957
更新日期:2012-05-01 00:00:00
abstract:INTRODUCTION:Two widely used outcome measures to assess functioning in neurological rehabilitation are the Functional Independence Measure (FIM™) and the Barthel Index. The current study aims to establish the equivalence of the total score of the FIM™ motor scale and the Barthel Index through the application of the Int...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-2225
更新日期:2017-05-16 00:00:00
abstract:OBJECTIVES:To investigate the effect of walkway length (5, 8 or 10 m) on measurements of comfortable and maximum walking speed. DESIGN:A cross-sectional study. SETTING:University-based rehabilitation centre. SUBJECTS:Patients (n = 25) with chronic stroke. METHODS:Timed walking with different walkway lengths (5, 8 a...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-0906
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of individualized manual physiotherapy and exercises compared with individualized exercises alone in patients with shoulder impingement syndrome. DESIGN:Randomized controlled trial. SUBJECTS:Patients with shoulder impingement of more than 4 weeks' duration. METHODS:Patients in the...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章,随机对照试验
doi:10.2340/16501977-1142
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:To update knowledge of the incidence of paroxysmal sympathetic hyperactivity (PSH, also referred to as dysautonomia), an emergency condition tentatively attributed to sympathetic paroxysms or diencephalic-hypothalamic disarrangement associated with severe diffuse brain axonal damage or hypoxia. This condition...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-0981
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:To report on the results of the consensus process integrating evidence from preliminary studies to develop the first version of a Comprehensive ICF Core Set and a Brief ICF Core Set for depression. METHODS:A formal decision-making and consensus process integrating evidence gathered from preliminary studies w...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.1080/16501960410016055
更新日期:2004-07-01 00:00:00
abstract::According to Antonovsky, the individual's sense of coherence is assumed to be crucial in coping with stressful life events. The purpose of this study was to investigate the associations between the sense of coherence of the spouses of stroke victims, the objective severity of the stroke and the spouses' perception of ...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.1080/165019702753714156
更新日期:2002-05-01 00:00:00
abstract:OBJECTIVE:The interhemispheric competition model proposes that the functional recovery of motor deficits in patients after stroke can be achieved by increasing the excitability of the affected hemisphere or decreasing the excitability of the unaffected hemisphere. We investigated whether bilateral repetitive transcrani...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章,随机对照试验
doi:10.2340/16501977-0454
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the impact of forced use therapy on posture in children with hemiplegic cerebral palsy. DESIGN:Single group pre- and post-training assessments. SUBJECTS:Eight children (mean age 10.5 years (standard deviation 1.26 years)) with hemiplegic cerebral palsy Levels I and II on the gross motor function...
journal_title:Journal of rehabilitation medicine
pub_type: 临床试验,杂志文章
doi:10.2340/16501977-0920
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:A technical consultation to develop a National Disability, Health and Rehabilitation Plan (NDHRP) for Egypt was carried out in 2015. Its overall goal was to improve health, functioning, well-being, quality of life, and participation of persons with disability in Egypt by supporting the Ministry of Health and ...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-2307
更新日期:2018-04-18 00:00:00
abstract::There is a need to develop a contemporary and internationally accepted conceptual description of physical and rehabilitation medicine (PRM). The process of evolving such a definition can now rely on the unifying conceptual model and taxonomy of the International Classification of Functioning, Disability and Health (IC...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-0044
更新日期:2007-05-01 00:00:00
abstract:OBJECTIVE:To examine wheelchair athletes' perceptions of wheelchair configuration in relation to aspects of mobility performance. METHODS:Nine elite wheelchair athletes from wheelchair basketball, wheelchair rugby and wheelchair tennis were interviewed using a semi-structured format. Interview transcripts were analyse...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-0490
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVE:To analyse factors related to subjective non-cognitive and cognitive complaints in patients with spontaneous subarachnoid haemorrhage. SUBJECTS:Twenty-seven patients with subarachnoid haemorrhage and 27 age-, sex- and education-matched healthy controls. METHODS:A battery of cognitive tests measuring visuo-s...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.1080/16501970310017414
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVE:Violence to disabled persons constitutes a major ethical problem. The European Academy of Rehabilitation Medicine has debated the matter; it presents this short report to alert a wider audience to the problem, with the aim of provoking debate and facilitating prevention. DESIGN:The Academy has produced a ful...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章,评审
doi:10.1080/16501970500476092
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:Guild boards and pulleys are apparatus commonly used to train cervical muscle function for their purported benefit in facilitating activity of the deeper muscle layers, although this effect has not been substantiated. The objective of this study was to compare the activity of the different layers of cervical ...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-1196
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:To compare walking dynamics and test-retest reliability for 2 frequently applied walk tests in polio survivors: the 6-minute walk test (6MWT) to walk as far as possible; and the 6-minute walking energy cost test (WECT) at comfortable speed. DESIGN:Observational study. PARTICIPANTS:Thirty-three polio survivo...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-2264
更新日期:2017-11-21 00:00:00
abstract:OBJECTIVE:To compare walking test results with walking in daily life, and to investigate the relationships between walking tests, walking activity in daily life, and perceived mobility problems in patients with post-poliomyelitis syndrome. SUBJECTS:Twenty-four ambulant patients with post-poliomyelitis syndrome. METHO...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.1080/16501970410021526
更新日期:2005-05-01 00:00:00
abstract:OBJECTIVE:To assess the association of cardiovascular autonomic balance with perceived functional impairment and pain among patients with chronic low back pain. DESIGN:A cross-sectional analysis of working patients with chronic low back pain. PATIENTS:Forty-six consecutive patients aged 24-45 years with chronic low b...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-0172
更新日期:2008-05-01 00:00:00
abstract::Physical & Rehabilitation Medicine (PRM) programmes in post-acute settings cover interventions for the rehabilitation of people with a variety of disabling health conditions. The setting of the intervention is more important than the timing and these programmes can be carried out in a variety of facilities. This paper...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-0960
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:To compare the effects of 2 postoperative regimens following carpal tunnel release: plaster casting and elastic bandaging. DESIGN:A randomized controlled study. PATIENTS:Patients with carpal tunnel syndrome and planned surgical carpal tunnel release were invited to participate. METHODS:A total of 94 patien...
journal_title:Journal of rehabilitation medicine
pub_type: 杂志文章
doi:10.2340/16501977-2788
更新日期:2021-01-14 00:00:00