PREPmate automated processor: comparison of automated and manual methods of liquid-based gynecologic sample preparation.

Abstract:

:The development of procedures for fully automated processing of liquid-based gynecologic samples has been the focus of considerable interest to the cytology laboratory. Liquid-based collection and processing technology has been shown to improve sample adequacy, resulting in an overall improvement in quality of sample preparations. PREPmate, an accessory to the PrepStain slide processor, automates the initial enrichment process of mixing and dispensing the specimen over a density gradient. This report describes a study evaluating cellularity and diagnostic reproducibility in SurePath samples processed using the PREPmate accessory compared to samples processed using a manual technique. Samples processed using the PREPmate accessory contained 8.3% more squamous cells. Exact diagnostic reproducibility between preparation types was 83.3%; when considering negative vs. abnormal (ASCUS+), in adequate samples, reproducibility was 100%.

journal_name

Diagn Cytopathol

journal_title

Diagnostic cytopathology

authors

Rowe LR,Marshall CJ,Bentz JS

doi

10.1002/dc.10193

subject

Has Abstract

pub_date

2002-11-01 00:00:00

pages

312-5

issue

5

eissn

8755-1039

issn

1097-0339

journal_volume

27

pub_type

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