Abstract：
:Data are presented indicating marked antineoplastic activity for cis-dichlorodiammineplatinum(II) in MOPC 104E myeloma. One-eighteenth of the dose that produced 100% cures can be combined with noncurative, low doses of cyclophosphamide and 1,3-bis(2-chloroethyl)-1-nitrosourea to produce antineoplastic activity of the same degree as that produced by much higher dose regimens which regularly produce cures. Since, in the past, results of therapeutic trials in plasma cell tumors in humans have paralleled results in this animal model, clinical trials of cis-dichlorodiammineplatinum in multiple myeloma appear warranted.
journal_name
Cancer Resjournal_title
Cancer researchauthors
Ghanta VK,Jones MT,Woodard DA,Durant JR,Hiramoto RNsubject
Has Abstractpub_date
1977-03-01 00:00:00pages
771-4issue
3eissn
0008-5472issn
1538-7445journal_volume
37pub_type
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