Abstract：
:This review discusses disorders of altered neutrophil number and function and provide a basic framework for patient evaluation and management. The sections begin with neutropenia, neutrophilia and neutrophil dysfunction with a general screening approach to differentiate common, more benign syndromes from rare, often more serious disorders. Also included is a detailed discussion of some specific primary neutrophil syndromes at the end of each section. Focus is placed on specific disorders that are clinically common or particularly instructive.
journal_name
Pediatr Clin North Amjournal_title
Pediatric clinics of North Americaauthors
Kyono W,Coates TDdoi
10.1016/s0031-3955(02)00030-5subject
Has Abstractpub_date
2002-10-01 00:00:00pages
929-71, viiiissue
5eissn
0031-3955issn
1557-8240pii
S0031-3955(02)00030-5journal_volume
49pub_type
杂志文章,评审abstract：:Prevention of enuresis has not been studied directly. Positive results from a randomized clinical trial evaluating early intervention for children at risk for enuresis would establish the value of prevention and help to promote its practice. Enuresis is not a disease process, and therefore a clinical trial may never b...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/s0031-3955(16)36078-3
更新日期：1986-08-01 00:00:00
abstract：:Recently, great progress has been made in the development of vaccines against Hib. Four polysaccharide-protein conjugate vaccines are actively being tested. Three of these (PRP-D, HbOC, and PRP-OMP) are currently licensed for use in children at 15-18 months of age. Clinical trials of these vaccines in infants are curr...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(16)36905-x
更新日期：1990-06-01 00:00:00
abstract：:Sleep problems are common in many pediatric medical disorders and complicate management and patient outcomes. A wide range of conditions, including asthma, cystic fibrosis, sickle cell disease, gastroesophageal reflux, neuromuscular diseases, scoliosis, craniofacial abnormalities, obesity, and chromosomal disorders, h...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(03)00185-8
更新日期：2004-02-01 00:00:00
abstract：:Sudden cardiac death (SCD) in children is the result of multiple etiologies and treatment (prophylaxis) must be tailored accordingly. In children who do not have congenital heart disease, surgical therapy of SCD typically consists of implantation of an internal defibrillator, with specific attention to the small size ...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2004.04.003
更新日期：2004-10-01 00:00:00
abstract：:The United States must improve its efforts to reduce teen pregnancy. We occupy an alarming position in the developed world from the standpoint of the magnitude of the pregnancy issue. While our society promotes sexuality to sell all sorts of consumer goods, it still refuses for the most part to make contraceptives fam...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(16)36690-1
更新日期：1989-06-01 00:00:00
abstract：:Evidence on the science of complementary and alternative medicine (CAM) in children with cancer is slowly evolving. Most parents of children with cancer want their children to receive state-of-the-art therapy, which generally includes chemotherapy, radiation, and surgery. Increasingly, they also want the concomitant u...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2007.10.007
更新日期：2007-12-01 00:00:00
abstract：:Attention-deficit/hyperactivity disorder is the most common neurobehavioral disorder of childhood, with most children maintaining symptoms of ADHD as adolescents and as adults. It is among the most common chronic conditions that primary care pediatricians see. Progress in brain imaging, genetics, neuropsychology, and ...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(03)00077-4
更新日期：2003-10-01 00:00:00
abstract：:Although primary immunodeficiencies typically present with recurrent, chronic, or severe infections, autoimmune manifestations frequently accompany these disorders and may be the initial clinical manifestations. The presence of 2 or more autoimmune disorders, unusual severe atopic disease, or a combination of these di...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2016.08.007
更新日期：2017-02-01 00:00:00
abstract：:Noncompliance with therapy is widespread in children, with potentially important implications in clinical practice and the research setting. Compliance with therapy is a critical element in the success of therapy, that is, for an efficacious medication to be effective, it must be taken. Demonstration of patterns of dr...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(05)70459-4
更新日期：1997-02-01 00:00:00
abstract：:Disorders of excessive sleepiness are uncommon in children. When they occur, the presentation is often consistent with the developmental age of the child and does not meet either historical or laboratory criteria determined with adults in mind. Because of these differences, the true diagnosis can be missed or inadequa...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(03)00175-5
更新日期：2004-02-01 00:00:00
abstract：:Neurodevelopmental disorders with identified genetic etiologies present a unique opportunity to study gene-brain-behavior connections in child psychiatry. Parsing complex human behavior into dissociable components is facilitated by examining a relatively homogenous genetic population. As children with developmental de...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/j.pcl.2011.06.010
更新日期：2011-08-01 00:00:00
abstract：:In children, laboratory evaluations can assist in the screening of patients for inflammatory disorders, confirm diagnoses, allow for monitoring of disease activity and response to therapy, and suggest prognoses and risk of morbidities associated with rheumatic diseases. This review provides an overview of the usefulne...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2012.03.008
更新日期：2012-04-01 00:00:00
abstract：:Headache is a common chronic and recurrent symptom in children and adolescents. The author discusses the prevalence of headache, its differential diagnosis, interpretation of symptoms, methods of assessment, and pharmacologic and nonpharmacologic treatment approaches. ...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(16)34683-1
更新日期：1984-10-01 00:00:00
abstract：:Most children with cancer are immunocompromised during therapy and for a variable period after completion of therapy. They are at an increased risk of infections, including vaccine-preventable infections. There is a reduction in immunity to vaccine-preventable diseases after completion of standard-dose chemotherapy an...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2007.10.012
更新日期：2008-02-01 00:00:00
abstract：:Telehealth is a promising new tool in medicine that has changed the landscape of medical care. The benefits of telehealth technology are immense, including improved access to care and potential savings in monetary and opportunity costs. Current challenges of incorporating telehealth services into regular clinical care...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2020.04.005
更新日期：2020-08-01 00:00:00
abstract：:This article describes important aspects of health-care quality, quality improvement (QI), patient safety (PS), and approaches to research on QI/PS efforts. Common terminology to facilitate an understanding of QI and PS research is reviewed. Models for understanding system and process performance are discussed. Introd...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2015.12.006
更新日期：2016-04-01 00:00:00
abstract：:Doctors need to acquire telehealth consultation skills to thrive in the increasingly pressurized health system of delivering high-quality, high-volume health care with a shrinking health care workforce. Telehealth consultations require the same degree of thoroughness and careful clinical judgment as face-to-face consu...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2020.04.013
更新日期：2020-08-01 00:00:00
abstract：:Children who have a dental home are more likely to receive preventative care, require fewer dental treatments, and are less likely to have dental disease. Many children demonstrate behavior management concerns that may impede families from establishing a dental home for their children. Conceptually, behavior concerns ...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2020.02.006
更新日期：2020-06-01 00:00:00
abstract：:Autologous and allogeneic hematopoietic stem cell transplantation (HSCT) can be used in the management of patients with autoimmune disorders. Experience gained in adults has helped to better define the conditioning regimens required and appropriate selection of patients who are most likely to benefit from autologous H...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2009.12.003
更新日期：2010-02-01 00:00:00
abstract：:ADHD is a syndrome that can be treated effectively, safely, and economically with stimulant medications. There is no equal alternative to these agents in short-term treatment of ADHD symptoms. However, many families seek alternatives to stimulants and other drug treatments for a variety of reasons. Alternative approac...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(05)70167-x
更新日期：1999-10-01 00:00:00
abstract：:Cow's milk allergy (CMA) affects 2% to 3% of young children and presents with a wide range of IgE and non-IgE-mediated clinical syndromes, which have a significant economic and lifestyle effect. It is logical that a review of CMA would be linked to a review of soy allergy because soy formula is often an alternative so...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2011.02.005
更新日期：2011-04-01 00:00:00
abstract：:In hyperinsulinemic hypoglycemia (HH) there is dysregulation of insulin secretion from pancreatic β-cells. Insulin secretion becomes inappropriate for the level of blood glucose leading to severe hypoglycemia. HH is associated with a high risk of brain injury because insulin inhibits lipolysis and ketogenesis thus pre...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2015.04.010
更新日期：2015-08-01 00:00:00
abstract：:Three pediatric hand injury subtypes and their management have been presented. Finger tip injuries, while often minor and self-healing in children, may require surgical repair if the nailbed is disrupted or if there has been significant skin or pad loss from the tip. The decision between local repair and skin graft or...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/s0031-3955(16)33144-3
更新日期：1975-05-01 00:00:00
abstract：:Human autoinflammatory diseases (except for the periodic fever, adenopathy, pharyngitis, aphthae syndrom) are a heterogeneous group of genetically determined diseases characterized by seemingly unprovoked inflammation, in the absence of autoimmune or infective causes. Tremendous advances in the understanding of these ...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2005.01.005
更新日期：2005-04-01 00:00:00
abstract：:The American family is changing. Pediatricians are increasingly aware of treating children within a family systems context. Patients present with a variety of biopsychosocial problems, and pediatrics must continue to adjust to fit the changing needs of children and their families. Pediatricians must view themselves as...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(16)38916-7
更新日期：1995-02-01 00:00:00
abstract：:Injuries to the pancreas and gastrointestinal tract following blunt abdominal trauma continue to be a significant cause of morbidity and mortality in the pediatric age group. Optimal treatment of these injuries is frequently hampered by considerable delays in diagnosis. Factors contributing to these delays include the...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/s0031-3955(16)33136-4
更新日期：1975-05-01 00:00:00
abstract：:This article describes the process of clinical assessment that may lead to differential treatment of psychiatric-related learning difficulties. The authors review differences in information processing among individuals with attention, affective, and primary thought disorders. ...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/s0031-3955(16)34578-3
更新日期：1984-04-01 00:00:00
abstract：:Despite many advances in the overall treatment of type I diabetes mellitus during the last few years, no major advance has been made in decreasing the mortality rate of diabetic ketoacidosis or hyperosmolar hyperglycemic nonketotic coma. A major concern in both of these disease states is the development of cerebral ed...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(16)36870-5
更新日期：1990-04-01 00:00:00
abstract：:Allogeneic hematopoietic stem cell transplantation from siblings, unrelated donors or HLA mismatched family members has become an important procedure to offer a chance of cure to children and adolescents with acute leukemia at high risk of relapse and those with certain genetic diseases. Bone marrow (BM) was the only ...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2010.01.004
更新日期：2010-02-01 00:00:00
abstract：:I have stressed the known medical and environmental factors associated with unexpected, sudden death in sports in children, and I have recommended restrictions or environmental alterations to prevent sudden death associated with an individual sport. Medical problems such as cardiomyopathies, posterior mitral valve lea...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/s0031-3955(16)34285-7
更新日期：1982-12-01 00:00:00
