Inositol 1,4,5-trisphosphate receptor/Ca(2+) channel modulatory role of chromogranins A and B.

abstract：:Child maltreatment (CM) not only has detrimental and lifelong psychological consequences, but also can lead to lasting alterations in core physiological systems--a biological memory of CM. Furthermore, some of these alterations might even be transmitted to the next generation. This article describes current knowledge ...

journal_title：Annals of the New York Academy of Sciences

authors： Schury K,Kolassa IT

更新日期：2012-07-01 00:00:00

abstract：:Propagation of a kerosene spray formed by a prefilming airblast atomizer within a pulsating flame has been investigated. The measurements were performed in a 400 kW single combustor rig at typical engine conditions of up to 0.8 MPa inlet pressure and 673 K inlet temperature. The homogeneity of the fuel spray propagati...

journal_title：Annals of the New York Academy of Sciences

authors： Schober P,Meier R,Schäfer O,Wittig S

更新日期：2002-10-01 00:00:00

abstract：:Methamphetamine (METH) is a major drug of abuse in the United States. A high dose of METH given to mice and rats causes long-lasting depletion of tyrosine hydroxylase activity, dopamine (DA), and DA-transporter (DAT) binding sites in the striatum. In human METH-abusers, a marked decrease of the DAT in the caudate puta...

journal_title：Annals of the New York Academy of Sciences

authors： Itzhak Y,Ali SF

更新日期：2002-06-01 00:00:00

abstract：:Results obtained from projects in which self-organizing musical structures spontaneously arise through electrical interface between the brain and generative musical systems are surveyed. This provides a springboard for examining important paradigm shifts taking place in our thinking about what musical forms can be and...

journal_title：Annals of the New York Academy of Sciences

authors： Rosenboom D

更新日期：2003-11-01 00:00:00

abstract：:Bioterrorism includes possible use of Weapons of Mass Destruction (WMD), preferably biological agents, by non-state terrorist groups as well as criminal clusters. The threat from terrorists to utilize biological agents to achieve goals is not new, but the threshold to realize the threats seems to be lower than previou...

journal_title：Annals of the New York Academy of Sciences

authors： Sandström G

更新日期：2000-01-01 00:00:00

abstract：:Proopiomelanocortin (POMC) and proenkephalin (PE) are synthesized at the endoplasmic reticulum and transported to the trans-Golgi network (TGN) where they are sorted and packaged into dense-core granules of the regulated secretory pathway (RSP). The mechanism of sorting POMC and PE to the RSP in neuroendocrine cells w...

journal_title：Annals of the New York Academy of Sciences

authors： Loh YP,Maldonado A,Zhang C,Tam WH,Cawley N

更新日期：2002-10-01 00:00:00

abstract：:Cities modify their local climate, and at the same time they suffer from the local impacts of climate change. Our paper discusses the progress and obstacles in three active research topics that contribute to increasing the capability within the urban climate research community for transferring local climate knowledge ...

journal_title：Annals of the New York Academy of Sciences

authors： Hidalgo J,Lemonsu A,Masson V

更新日期：2019-01-01 00:00:00

abstract：:Leukoplakia in the oral cavity has been used as a putative surrogate marker of head and neck cancer development. A class of chemoprevention compounds, called protease inhibitors, has been shown in vitro and in animal models to effectively suppress premalignant lesions. Bowman-Birk inhibitor (BBI) is a protease inhibit...

journal_title：Annals of the New York Academy of Sciences

authors： Meyskens FL

更新日期：2001-12-01 00:00:00

abstract：:Although many authors have considered a direct interaction between allergic reactions and behavioral changes, supporting evidence has been elusive. In this series of studies we show that after oral or nasal ovalbumin (OVA) challenge, allergic mice present increased Fos expression in the paraventricular nucleus of the ...

journal_title：Annals of the New York Academy of Sciences

authors： Costa-Pinto FA,Basso AS,De Sá-Rocha LC,Britto LR,Russo M,Palermo-Neto J

更新日期：2006-11-01 00:00:00

abstract：:Asbestos-induced pleural fibrosis is the most common radiographic abnormality among asbestos-exposed persons. Circumscribed pleural plaques and diffuse pleural thickening account for more than 90% of the asbestos-induced chest wall abnormalities, and their prevalence is expected to increase for the next 15 to 20 years...

journal_title：Annals of the New York Academy of Sciences

authors： Schwartz DA

更新日期：1991-12-31 00:00:00

abstract：:Our recent studies in non-human primates have identified and characterized cerebro-ponto-cerebellar pathways involved in the control of vergence eye movements. Specifically, within the deep cerebellar nuclei and nucleus reticularis tegmenti pontis, we have identified neurons that are related to either the near respons...

journal_title：Annals of the New York Academy of Sciences

authors： Gamlin PD

更新日期：2002-04-01 00:00:00

abstract：:It is well established for both rat and man that the total testosterone concentration within the testis is far higher than that in serum. We know for the rat that intratesticular testosterone can be reduced by 50-60% without an adverse effect on spermatogenesis but that the required intratesticular testosterone concen...

journal_title：Annals of the New York Academy of Sciences

authors： Jarow JP,Zirkin BR

更新日期：2005-12-01 00:00:00

abstract：:Taken together with electrophysiological data, these results suggest that in states of DA deficiency, systemically administered L-dopa or DA agonist drugs inhibit cell firing in the major output nuclei of the basal ganglia (GPI and SNPR). We propose that DA produces this net effect by a direct influence on the striato...

journal_title：Annals of the New York Academy of Sciences

authors： Wooten GF

更新日期：1997-12-19 00:00:00

abstract：:Four weeks immobilization of the right leg of aged rats (26 months old) caused a marked 31% and 27% reduction of muscle mass of the plantaris and soleus muscles, respectively. In animals treated with 0.6 mg/kg body weight of growth hormone (GH), the reduction of weight of the above muscles was only 14.7 and 16.1%, res...

journal_title：Annals of the New York Academy of Sciences

authors： Fares FA,Gruener N,Carmeli E,Reznick AZ

更新日期：1996-06-15 00:00:00

abstract：:We have shown that the medial preoptic area (MPO) in the hypothalamus is a major site where interferon (IFN)-alpha acts to induce suppression of splenic natural killer (NK) cell activity through an activation of sympathetic nervous system (SNS) in rats. Here, we discuss the hypothalamic mechanisms of the cytokine acti...

journal_title：Annals of the New York Academy of Sciences

authors： Katafuchi T,Duan S,Take S,Yoshimura M

更新日期：2009-02-01 00:00:00

abstract：:During their development, mononuclear phagocytes express a changing profile of proteinases that may participate in the degradation of elastin and other extracellular matrix components. Neutrophil elastase is produced and stored in azurophil-like granules in immature mononuclear phagocytes. Monocytes contain small amou...

journal_title：Annals of the New York Academy of Sciences

authors： Shapiro SD,Campbell EJ,Welgus HG,Senior RM

更新日期：1991-01-01 00:00:00

abstract：:Learning theory proposes that drug seeking is a synthesis of multiple controllers. Whereas goal-directed drug seeking is determined by the anticipated incentive value of the drug, habitual drug seeking is elicited by stimuli that have formed a direct association with the response. Moreover, drug-paired stimuli can tra...

journal_title：Annals of the New York Academy of Sciences

authors： Hogarth L,Balleine BW,Corbit LH,Killcross S

更新日期：2013-04-01 00:00:00

abstract：:Although much work has been done in the field of circulating DNA, no definitive information on sequencing data of total circulating DNA is available. Characterization of total circulating DNA by sequence analysis may give valuable information about the origin and function of these nucleic acid molecules. Circulating D...

journal_title：Annals of the New York Academy of Sciences

authors： van der Vaart M,Pretorius PJ

更新日期：2008-08-01 00:00:00

abstract：:The flash thermal diffusivity measurement technique is applied to tissue for the first time. Making use of its minimal contact with the specimen, the flash technique is extended to allow for well-defined, biaxial, finite strain. As an example application, the radial component of thermal diffusivity of bovine descendin...

journal_title：Annals of the New York Academy of Sciences

authors： Doss DJ,Humphrey JD,Wright NT

更新日期：1998-09-11 00:00:00

abstract：:We propose a model for signaling events induced by fluid shear stress that incorporates many of the features discussed in this paper (FIG. 4). First, heterotrimeric G-proteins, as well as a small G-proteins, are activated by flow. Indeed, a G protein appears to be required for ERK1/2 activation by flow because ERK1/2 ...

journal_title：Annals of the New York Academy of Sciences

authors： Ishida T,Takahashi M,Corson MA,Berk BC

更新日期：1997-04-15 00:00:00

abstract：:This paper summarizes the goals of this section and considers current knowledge about the association between hormonal changes that occur over pubertal development and the changes in behavior and brain function over the adolescent period. It reviews the cascade of neural and hormonal changes that occur with puberty; d...

journal_title：Annals of the New York Academy of Sciences

authors： Cameron JL

更新日期：2004-06-01 00:00:00

abstract：:Exposure to phosphine (PH3 ), a common grain fumigant, is characterized by diverse nonspecific symptoms and a high mortality rate. Although PH3 poisoning is thought to target oxidative respiration, the exact mechanism of action remains largely unknown, resulting in limited treatment options. In our study, the effects ...

journal_title：Annals of the New York Academy of Sciences

authors： Tuet WY,Racine MC,Jennings L,Pierce SA,Tressler J,McCranor BJ,Wong B

更新日期：2020-11-01 00:00:00

abstract：:Sodium channels from rat and rabbit skeletal muscle have been isolated, characterized, and functionally reconstituted. These channel proteins closely resemble those purified from the eel electroplax and from rat brain. Work now in progress on the determination of the primary sequence of the 260 kDa subunit through the...

journal_title：Annals of the New York Academy of Sciences

authors： Barchi RL

更新日期：1986-01-01 00:00:00

abstract：:Effective emotion regulation may promote resilience and preschool classroom adjustment by supporting adaptive peer interactions and engagement in learning activities. We investigated how hypothalamus-pituitary-adrenal axis (HPA) regulation, cardiac reactivity, and classroom emotion displays related to adjustment among...

journal_title：Annals of the New York Academy of Sciences

authors： Miller AL,Seifer R,Stroud L,Sheinkopf SJ,Dickstein S

更新日期：2006-12-01 00:00:00

abstract：:The use of animal cells, tissues, or organs for humans is being investigated as an alternative to allotransplantation and as therapy for a broad range of disease states including diabetes, Parkinson's disease, and neurologic pain control. The risk of transmitting novel infections with these tissues, xenozoonoses, has ...

journal_title：Annals of the New York Academy of Sciences

authors： Michaels M

更新日期：1998-12-30 00:00:00

abstract：:We compared the expression of target genes of Hedgehog/Patched signaling in ovarian fibromas and ovarian dermoids. We noted that high levels of SHH appear almost regularly, especially in dermoids, usually accompanied by increased expression of SMO. GLI overexpression does not coincide with that of PTCH. Loss of hetero...

journal_title：Annals of the New York Academy of Sciences

authors： Levanat S,Musani V,Komar A,Oreskovic S

更新日期：2004-12-01 00:00:00

abstract：:The skeletal dysplasias or osteochondrodysplasias are a clinically and genetically heterogeneous group of disorders of bone and/or cartilage. They are characterized by abnormalities in pattering, linear growth, differentiation, and maintenance of the human skeleton. While they have been considered to be generalized di...

journal_title：Annals of the New York Academy of Sciences

authors： Rimoin DL,Cohn D,Krakow D,Wilcox W,Lachman RS,Alanay Y

更新日期：2007-11-01 00:00:00

abstract：:Allergic contact dermatitis is a common inflammatory skin disease caused by T cells that recognize environmental and industrial allergens (i.e., haptens). Langerhans' cells (LC), which are skin-specific and "immature" members of the dendritic cell (DC) family of antigen-presenting cells, play crucial roles in the indu...

journal_title：Annals of the New York Academy of Sciences

authors： Takashima A,Mummert M,Kitajima T,Matsue H

更新日期：2000-01-01 00:00:00

abstract：:We studied hearing impairment and cochlear ultrastructure in C57BL/6J mice containing the cpk mutant gene. Heterozygous cpk/+ mutant mice, 6-8 months old, showed a marked hearing loss as demonstrated by auditory evoked potentials with some showing hearing loss at 90 db sound pressure. Ultrastructural studies of first ...

journal_title：Annals of the New York Academy of Sciences

authors： Cho H,Buchanan J,Strong D,Yamada Y,Yoo TJ

更新日期：1991-01-01 00:00:00

abstract：:GABAA receptor heterogeneity is based on the combinatorial assembly of a large family of subunits into distinct receptor subtypes. A neuron-specific expression pattern of receptor subtypes has been demonstrated in adult rat brain, which can be reproduced in vitro in primary neuron cultures. This suggests that genetic ...

journal_title：Annals of the New York Academy of Sciences

authors： Penschuck S,Paysan J,Giorgetta O,Fritschy JM

更新日期：1999-04-30 00:00:00