Cytokine-induced suppression of medial preoptic neurons: mechanisms and neuroimmunomodulatory effects.

abstract：:The dynamics and kinematics of saccades in a patient with severe ocular myasthenia were studied before and after treatment with intravenous immunoglobulin (IVIG). Before therapy, horizontal saccades were hypometric, but faster than similar-sized saccades made by normal subjects. During a 5-minute test period, saccades...

journal_title：Annals of the New York Academy of Sciences

authors： Serra A,Thurtell MJ,Leigh RJ

更新日期：2009-05-01 00:00:00

abstract：:T-lymphocytes from three species of New World monkeys were susceptible to transformation in vitro with human T-cell leukemia virus. Marmoset T-lymphocytes transformed in vitro with HVS or HVA, T-lymphotropic herpesviruses of New World monkeys, were also transformed with HTLV resulting in doubly transformed T-cells. Th...

journal_title：Annals of the New York Academy of Sciences

authors： Falk LA Jr,Byington R,Silva DP

更新日期：1984-01-01 00:00:00

abstract：:Clostridium difficile infection, also known as C. difficile-associated diarrhea (CDAD), is the most common cause of nosocomial diarrhea, typically initiated by the use of broad-spectrum antibiotics that disrupt gut flora, thereby allowing C. difficile to proliferate. It is an increasing cause of morbidity and mortalit...

journal_title：Annals of the New York Academy of Sciences

authors： Sears P,Ichikawa Y,Ruiz N,Gorbach S

更新日期：2013-07-01 00:00:00

abstract：:The aim of this study was to clarify the role of nitric oxide (NO) and lipid peroxidation (LPO) processes as well as the contribution of various neurotransmitters in pathophysiological mechanisms of neurotoxicity induced by amphetamine (AMPH). NO level was determined directly in brain tissues using electron paramagnet...

journal_title：Annals of the New York Academy of Sciences

authors： Bashkatova V,Kraus MM,Vanin A,Hornick A,Prast H

更新日期：2004-10-01 00:00:00

abstract：:A diverse array of organisms live longer under dietary restriction. Here, a hypothesis is proposed as a framework for interpreting this phenomenon. Dietary restriction is explained in terms of evolution and antagonistic pleiotropy. Focusing on the decline in reproductive capacity seen in dietary restriction, it is sub...

journal_title：Annals of the New York Academy of Sciences

authors： Koochmeshgi J

更新日期：2004-06-01 00:00:00

abstract：:Significant advances have been made over the past few years concerning the cellular and molecular events underlying neuron death. Recently, it is becoming increasingly clear that some of genes induced during cerebral ischemia may actually serve to rescue the cell from death. However, the injured cell may not be capabl...

journal_title：Annals of the New York Academy of Sciences

authors： Yenari MA,Dumas TC,Sapolsky RM,Steinberg GK

更新日期：2001-06-01 00:00:00

abstract：:The present experiments were conducted to determine the effects of neurotensin on secretion of a variety of anterior pituitary hormones. Conscious rats with indwelling cannulae in the third ventricle and external jugular vein were used and the effects on plasma hormone levels measured by radioimmunoassay. Neurotensin ...

journal_title：Annals of the New York Academy of Sciences

authors： McCann SM,Vijayan E,Koenig J,Krulich L

更新日期：1982-01-01 00:00:00

abstract：:The formation of metastasis is a dreadful complication of cancer that is associated with a poor prognosis. Several clinical observations and experimental findings indicate that the metastatic process is nonrandom and involves a sequence of multistep events that may all be targeted for therapy. This includes angiogenes...

journal_title：Annals of the New York Academy of Sciences

authors： Laferriere J,Houle F,Huot J

更新日期：2002-11-01 00:00:00

abstract：:DNA microarray analysis was conducted to investigate the transcriptional responses of the human monocytic leukemia cell line THP-1 to infection by Chlamydia trachomatis or Coxiella burnetii. RNA was isolated from mock infected cells and cells infected for 36 hours using TRIzol reagent. Biotinylated probes synthesized ...

journal_title：Annals of the New York Academy of Sciences

authors： Ren Q,Robertson SJ,Howe D,Barrows LF,Heinzen RA

更新日期：2003-06-01 00:00:00

abstract：:It has previously been shown that stimulation of muscarinic m1 or m3 receptors can, by generating diacylglycerol (DAG) and activating protein kinase C (PKC), accelerate the breakdown of the amyloid precursor protein (APP) to form soluble, non-amyloidogenic peptides (APPs). This relationship has been demonstrated in hu...

journal_title：Annals of the New York Academy of Sciences

authors： Lee RK,Jimenez J,Cox AJ,Wurtman RJ

更新日期：1996-01-17 00:00:00

abstract：:An increasing amount of evidences suggests that galanin plays an important role in the regulation of reproduction in the rat. Galanin is colocalized with luteinizing hormone-releasing hormone (LHRH) in a subset of LHRH neurons, and the pattern of coexpression is sexually dimorphic, with a higher incidence of colocaliz...

journal_title：Annals of the New York Academy of Sciences

authors： Merchenthaler I

更新日期：1998-12-21 00:00:00

abstract：:Plasticity is a fundamental property of the neural system controlling breathing. One frequently studied model of respiratory plasticity is long-term facilitation of phrenic motor output (pLTF) following acute intermittent hypoxia (AIH). pLTF arises from spinal plasticity, increasing respiratory motor output through a ...

journal_title：Annals of the New York Academy of Sciences

authors： Dale-Nagle EA,Hoffman MS,MacFarlane PM,Satriotomo I,Lovett-Barr MR,Vinit S,Mitchell GS

更新日期：2010-06-01 00:00:00

abstract：:Over most of the past century, it was thought that the adult brain was completely incapable of generating new neurons. However, in the last decade, the development of new techniques has resulted in an explosion of new research showing that (i) neurogenesis, the birth of new neurons, is not restricted to embryonic deve...

journal_title：Annals of the New York Academy of Sciences

authors： Arlotta P,Magavi SS,Macklis JD

更新日期：2003-06-01 00:00:00

abstract：:Peripheral administration of lipopolysaccharide (LPS) in an amount that produces acute stress has been found to affect the catecholamine systems in the brain. Acute peripheral LPS administration activated norepinephrine (NE) metabolism in the locus ceruleus (LC). Approximately 40% of murine LC neurons project to the o...

journal_title：Annals of the New York Academy of Sciences

authors： Ota A,Mori K,Kaneko YS,Nakashima A,Nagatsu I,Nagatsu T

更新日期：2008-12-01 00:00:00

abstract：:Nitric oxide (NO) bioavailability is crucial for normal vascular endothelial function and health. Recent studies have demonstrated an endocrine role for NO equivalents that may be transported in the blood to peripheral tissue beds, where under hypoxic conditions they can liberate NO and cause vasodilation. Exercise tr...

journal_title：Annals of the New York Academy of Sciences

authors： Stabler T,Kenjale A,Ham K,Jelesoff N,Allen J

更新日期：2010-08-01 00:00:00

abstract：:One of the most important advances in perinatal health care is the use of antepartum fetal testing. Antepartum fetal testing methods may include inexpensive tests such as fetal kick counts or tests that can be quite expensive such as non-stress tests, fetal biophysical profiles, and Doppler assessments as well as inva...

journal_title：Annals of the New York Academy of Sciences

authors： Vintzileos AM

更新日期：2000-01-01 00:00:00

abstract：:People discover rather than choose their sexual interests. The process of discovery typically begins before the onset of puberty and is associated with an increase in the secretion of sex hormones from the adrenal glands. However, the determinants of the direction of sexual interest, in the sense of preferences for th...

journal_title：Annals of the New York Academy of Sciences

authors： Quinsey VL

更新日期：2003-06-01 00:00:00

abstract：:For more than 10 years umbilical cord blood (UCB) has been used as an alternative source of hematopoietic stem cells for allogeneic transplantation. Although the clinical results are encouraging, UCB is associated with delayed engraftment. To address these issues we have used the NOD/SCID mouse model to study the engr...

journal_title：Annals of the New York Academy of Sciences

authors： Fibbe WE,Noort WA,Schipper F,Willemze R

更新日期：2001-06-01 00:00:00

abstract：:Iddm4 is a dominant non-major histocompatibility complex (MHC) determinant of diabetes susceptibility in BBDR rats treated with poly I:C, plus depletion of regulatory T cells. In congenic MHC-identical normal WF rats, Iddm4(d) sensitively and specifically predicts induced diabetes. We report a new diabetes-susceptible...

journal_title：Annals of the New York Academy of Sciences

authors： Blankenhorn EP,Descipio C,Rodemich L,Cort L,Leif JH,Greiner DL,Mordes JP

更新日期：2007-04-01 00:00:00

abstract：:Using a newly developed algorithm in conjunction with the front tracking scheme, we have evaluated the transport associated with a deformable bubble moving in a tube in the presence of a soluble or an insoluble surfactant. Such evaluations are useful to the understanding of gas embolism--a common syndrome for decompre...

journal_title：Annals of the New York Academy of Sciences

authors： Ayyaswamy PS,Zhang J,Eckmann DM

更新日期：2006-09-01 00:00:00

abstract：:Intraocular lesions occurred in 55 of 70 sarcoidosis patients (78.6%) and their intraocular findings were biomicroscopically analyzed. Intraocular lesions were observed bilaterally in 54 of 55 patients (98.0%) and these various lesions occurred simultaneously or within a short period in almost all tissues of the eyeba...

journal_title：Annals of the New York Academy of Sciences

authors： Iwata K,Nanba K,Sobue K,Abe H

更新日期：1976-01-01 00:00:00

abstract：:The presence in the serum of specific autoantibodies, such as antinuclear antibodies (ANA), anti-double-stranded DNA (anti-dsDNA), and antiextractable nuclear antigens (anti-ENA), is one of the diagnostic criteria for autoimmune rheumatic disease, and the requests for these tests in the last few years have grown remar...

journal_title：Annals of the New York Academy of Sciences

authors： Bonaguri C,Melegari A,Dall'Aglio P,Ballabio A,Terenziani P,Russo A,Battistelli L,Aloe R,Camisa R,Campaniello G,Sartori E,Monica C

更新日期：2009-09-01 00:00:00

abstract：:Little is known about the role of the basolateral amygdala (BLA) in regulating hypothalamic-pituitary-adrenal (HPA) activity, particularly chronic stress-induced HPA activity. In the current studies, we examined the effects of manipulations of the BLA on HPA responses to the eighth restraint, to novel restraint after ...

journal_title：Annals of the New York Academy of Sciences

authors： Bhatnagar S,Vining C,Denski K

更新日期：2004-12-01 00:00:00

abstract：:In thalassemia, iron overload is the joint outcome of excessive iron absorption and transfusional siderosis. While iron absorption is limited by a physiologic ceiling of about 3 mg/d, plasma iron turnover in thalassemia may be 10 to 15 times normal, caused by the wasteful, ineffective erythropoiesis of an enormously e...

journal_title：Annals of the New York Academy of Sciences

authors： Hershko C,Link G,Cabantchik I

更新日期：1998-06-30 00:00:00

abstract：:There is a growing interest in the effectiveness of mindfulness meditation for sleep disturbed populations. Our study sought to evaluate the effect of mindfulness meditation interventions on sleep quality. To assess for relative efficacy, comparator groups were restricted to specific active controls (such as evidenced...

journal_title：Annals of the New York Academy of Sciences

authors： Rusch HL,Rosario M,Levison LM,Olivera A,Livingston WS,Wu T,Gill JM

更新日期：2019-06-01 00:00:00

abstract：:Continuous infusion (CI) of coagulation factor concentrates has been used since the early 1990s. Recent reports of the occurrence of an inhibitor after CI have raised concerns about this method of treatment. We conducted a retrospective study to investigate the development of inhibitors after CI of Factor VIII concent...

journal_title：Annals of the New York Academy of Sciences

authors： von Auer Ch,Oldenburg J,von Depka M,Escuriola-Ettinghausen C,Kurnik K,Lenk H,Scharrer I

更新日期：2005-06-01 00:00:00

abstract：:The CD27(+) IgD(+) B cell population, known as IgM memory, reduces with age. It is thought that this population is responsible for pneumococcal polysaccharide T-independent responses, and that the age-related reduction might be partially responsible for the increased susceptibility of older people to bacterial pathoge...

journal_title：Annals of the New York Academy of Sciences

authors： Martin V,Wu YC,Kipling D,Dunn-Walters DK

更新日期：2015-12-01 00:00:00

abstract：:In humans the influence of prior vestibular stimulation (3, 6, 9, 12, and 18 degrees/second2 for 10 seconds) and subsequent whole-field optokinetic stimulation (30, 60, 90, 120, and 180 degrees/second for 1 minute) or the presentation of a stationary pattern on after-nystagmus (AN) was studied. For comparison, pure ve...

journal_title：Annals of the New York Academy of Sciences

authors： Koenig E,Dichgans J

更新日期：1981-01-01 00:00:00

abstract：:We compare the evidence from human neuroimaging studies for and against two of the major hypotheses of how alterations in the brain's reward system underlie addiction. One of these, the impulsivity hypothesis, proposes that addiction is characterized by excessive sensitivity to reward combined with a failure of inhibi...

journal_title：Annals of the New York Academy of Sciences

authors： Hommer DW,Bjork JM,Gilman JM

更新日期：2011-01-01 00:00:00

abstract：:Left ventricular (LV) wall motion abnormalities reflect regional nonuniform contraction which may be arrhythmogenic. We studied sarcomere mechanics and force development (F) in uniform and nonuniform trabeculae using a model in which half of the muscle can be rendered weak by exposure to low [Ca2+]o. Stretch allowed t...

journal_title：Annals of the New York Academy of Sciences

authors： ter Keurs HE,Diao N,Deis NP

更新日期：2010-02-01 00:00:00