Abstract：
:Recognition of facial expressions of emotion was investigated in people with medicated and unmedicated Parkinson's disease (PD) and matched controls (unmedicated PD, n=16; medicated PD, n=20; controls, n=40). Participants in the medicated group showed some visual impairment (impaired contrast sensitivity) and performed less well on perception of unfamiliar face identity, but did not show significant deficits in the perception of sex, gaze direction, or familiar identity from the face. For both Parkinson's disease groups, there was evidence of impaired recognition of facial expressions in comparison to controls. These deficits were more consistently noted in the unmedicated group, who were also found to perform worse than the medicated group at recognising disgust from prototypical facial expressions, and at recognising anger and disgust in computer-manipulated images. Although both Parkinson's disease groups showed impairments of facial expression recognition, the consistently worse recognition of disgust in the unmedicated group is consistent with the hypothesis from previous studies that brain regions modulated by dopaminergic neurons are involved in the recognition of disgust.
journal_name
Neuropsychologiajournal_title
Neuropsychologiaauthors
Sprengelmeyer R,Young AW,Mahn K,Schroeder U,Woitalla D,Büttner T,Kuhn W,Przuntek Hdoi
10.1016/s0028-3932(02)00295-6subject
Has Abstractpub_date
2003-01-01 00:00:00pages
1047-57issue
8eissn
0028-3932issn
1873-3514pii
S0028393202002956journal_volume
41pub_type
杂志文章相关文献
NEUROPSYCHOLOGIA文献大全abstract：:Memory for visual items can evoke activity in visual processing regions, which is typically assumed to reflect conscious remembering. However, based on previous findings, we hypothesized that such activity in early visual areas (BA17, BA18) may reflect priming, a form of nonconscious memory. We tested this hypothesis ...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2006.06.021
更新日期：2006-01-01 00:00:00
abstract：:This experiment investigated whether Parkinson's disease (PD) patients experience problems in producing stroke size, stroke duration or both, in a handwriting task. Thirteen PD patients and 15 elderly controls wrote four patterns of varying complexity on a digitizer tablet. The participants were instructed to execute ...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/s0028-3932(98)00122-5
更新日期：1999-06-01 00:00:00
abstract：:In Experiment I normal subjects performed the classical clinical line-bisection task, and demonstrated a left-side underestimation. In Experiment II subjects maintained fixation upon a central position and adjusted a rod passing through this fixation point so that both extremities were judged equal. The left-side unde...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/0028-3932(85)90029-6
更新日期：1985-01-01 00:00:00
abstract：:Patients with right hemisphere injury frequently neglect to cancel targets primarily in the left part of the page nearest the body. Since this region is diagonally opposite the area from where such patients usually begin cancelling, near left ('diagonal') neglect may be consequent to stimulus order effects ('fatigue')...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/s0028-3932(97)00067-5
更新日期：1997-11-01 00:00:00
abstract：:It has been proposed that actions are intrinsically linked to perception. The idea behind these theories is that observing, imagining or in any way representing an action excites the motor programs used to execute that same action. There is neurophysiological evidence that neurons in premotor cortex of monkeys respond...
journal_title：Neuropsychologia
pub_type： 杂志文章,评审
doi：10.1016/j.neuropsychologia.2004.11.012
更新日期：2005-01-01 00:00:00
abstract：:The present study aimed to determine whether the bradykinesia of Parkinson's disease (PD) patients during the execution of reaching-grasping movements (i) is related to an impaired implementation of movement parameters and (ii) selectively involves the control of reach and/or grasp movements. We compared the kinematic...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2004.06.009
更新日期：2005-01-01 00:00:00
abstract：:To delineate the time course and processing stages of pitch encoding at the level of the supratemporal plane, the present study recorded evoked magnetic fields in response to rippled noise (RN) stimuli. RN largely masks simple tonotopic representations and addresses pitch processing within the temporal domain (periodi...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2004.04.022
更新日期：2004-01-01 00:00:00
abstract：:The brain operates via networked activity in separable groups of regions called modules. The quantification of modularity compares the number of connections within and between modules, with high modularity indicating greater segregation, or dense connections within sub-networks and sparse connections between sub-netwo...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2019.05.021
更新日期：2019-08-01 00:00:00
abstract：:Using repetitive transcranical magnetic stimulation (rTMS), we investigated the functional relevance of posterior parietal cortex for categorical and coordinate judgements in the spatial imagery domain. In the coordinate task, subjects were asked to imagine two analogue clock faces based on acoustically presented pair...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2006.01.017
更新日期：2006-01-01 00:00:00
abstract：:Apathy, usually defined as loss of motivation, is common in both neurodegenerative conditions such as Alzheimer's disease, and acute neurological disorders such as stroke. Neuroradiological studies on the imaging correlates of apathy have used a variety of methods such as structural and functional magnetic resonance i...
journal_title：Neuropsychologia
pub_type： 杂志文章,评审
doi：10.1016/j.neuropsychologia.2018.01.042
更新日期：2018-09-01 00:00:00
abstract：:Affecting up to 4-10% of the population, dyslexia is a highly prevalent, childhood onset developmental disorder adversely influencing multiple domains of adaptive functioning throughout the lifespan. The present brain imaging study was conducted in order to investigate the neuroanatomical correlates of developmental d...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2004.06.023
更新日期：2005-01-01 00:00:00
abstract：:Action observation and imitation have been found to influence movement in people with Parkinson's disease (PD), but simple visual stimuli can also guide their movement. To investigate whether action observation may provide a more effective stimulus than other visual cues, the present study examined the effects of obse...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2020.107690
更新日期：2020-11-28 00:00:00
abstract：:The stability of cognitive control processes over time can be indexed by trial-to-trial variability in reaction time (RT). Greater RT variability has been interpreted as an indicator of executive dysfunction, inhibitory inefficiency, and excessive mental noise. Previous studies have demonstrated that combat veterans w...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2013.10.008
更新日期：2013-12-01 00:00:00
abstract：:The recent development of noninvasive methods for measuring local rates of energy metabolism or blood flow in the brain has made it possible to investigate functional neuroanatomy in healthy human subjects. The best of these methods, high resolution measurement of regional cerebral blood flow (rCBF) with positron emis...
journal_title：Neuropsychologia
pub_type： 杂志文章,评审
doi：10.1016/0028-3932(91)90009-w
更新日期：1991-01-01 00:00:00
abstract：:Previous behavioral studies have shown that individuals with autism are less hindered by interference from global processing during the performance of lower-level perceptual tasks, such as finding embedded figures. The primary goal of this study was to examine the brain manifestation of such atypicality in high-functi...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2011.04.005
更新日期：2011-06-01 00:00:00
abstract：:It has been proposed that patients with spatial neglect fail to respond appropriately toward stimuli opposite their brain lesion because they have an impairment of directing attention. However, a disorder of 'intention' - or movement initiation - has also been demonstrated in this condition. Recently, the paths of neg...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/s0028-3932(99)00083-4
更新日期：2000-01-01 00:00:00
abstract：:Amblyopic subjects show a wide range of changes within the visual system, starting from deficits in simple perceptual processing up to changes of higher functions of the visual dorsal pathway. Recent studies suggest that subjects with amblyopia also demonstrate alterations in visuo-spatial attention. In contrast to no...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2010.02.028
更新日期：2010-05-01 00:00:00
abstract：:Visual objects can often be analyzed as hierarchical in structure, composed of local elements that are spatially arranged to form a global shape. The brain mechanisms involved in the analysis of hierarchical figures have been under considerable scrutiny in recent years, and one of the many interesting features that ha...
journal_title：Neuropsychologia
pub_type： 临床试验,杂志文章
doi：10.1016/s0028-3932(99)00080-9
更新日期：2000-01-01 00:00:00
abstract：:Functional imaging studies have identified a dorsal fronto-parietal network whose activity reflects shifts of attention in space and is sensitive to the behavioural relevance of stimuli. In patients with severe deficits of spatial attention this network is often structurally preserved. Here, we show that resting-state...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2016.07.012
更新日期：2016-11-01 00:00:00
abstract：:Findings of pharmacological studies that have investigated the involvement of specific regions of the brain in recognition memory are reviewed. The particular emphasis of the review concerns what such studies indicate concerning the role of the perirhinal cortex in recognition memory. Most of the studies involve rats ...
journal_title：Neuropsychologia
pub_type： 杂志文章,评审
doi：10.1016/j.neuropsychologia.2012.07.034
更新日期：2012-11-01 00:00:00
abstract：:A weak central coherence theory in autism spectrum disorder (ASD) proposes that a cognitive bias toward local processing in ASD derives from a weakness in integrating local elements into a coherent whole. Using this theory, we hypothesized that shape perception through active touch, which requires sequential integrati...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2011.12.024
更新日期：2012-04-01 00:00:00
abstract：:The selective attention to facial emotion and identity was investigated in 12 patients with schizophrenia and 12 healthy participants. Both patients and controls were required to perform two classification tasks (according either to identity or emotion). Two separate values for identity (person A/person B) and for emo...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/s0028-3932(01)00114-2
更新日期：2002-01-01 00:00:00
abstract：:The Stroop is a classical paradigm that presumably involves the inhibition of automatic responses and is frequently used to assess the frontal lobe functions. We investigated the effect of discrete prefrontal lesions in a Stroop task. A sample of 32 patients with frontal lesions were matched with normal controls by se...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/0028-3932(94)00116-7
更新日期：1995-03-01 00:00:00
abstract：:The 'dysexecutive syndrome' represents a major challenge to functional recovery and adaptation following brain injury--and an important target for rehabilitation. Previous reports of everyday difficulties, and performance on complex, life-like tasks, indicate that an adequately represented goal may become neglected as...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/s0028-3932(01)00094-x
更新日期：2002-01-01 00:00:00
abstract：:Patients with visual field disorders often exhibit impairments in visual exploration and a typical defective oculomotor scanning behaviour. Recent evidence [Bolognini, N., Rasi, F., Coccia, M., & Làdavas, E. (2005b). Visual search improvement in hemianopic patients after audio-visual stimulation. Brain, 128, 2830-2842...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2008.10.008
更新日期：2009-01-01 00:00:00
abstract：:Number processing is known to involve several sites within the posterior regions of parietal cortex. Here, we investigated whether neural activity in the inferior parietal lobule (IPL) is essential for number processing, by observing the effects of interfering with its activity during the execution of a standard numbe...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2004.05.005
更新日期：2004-01-01 00:00:00
abstract：:The personality trait of novelty seeking (NS) has been associated with the long variant of the dopamine D4 receptor (L-DRD4) VNTR polymorphism. This is the first study to examine the influence of L-DRD4 polymorphism on some of the cognitive (i.e. decision making) and emotional underpinnings of the NS phenotype. One hu...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2009.02.005
更新日期：2009-06-01 00:00:00
abstract：:Twenty boys with developmental coordination disorder (DCD), 11 of whom had associated attention deficit disorder (ADD), were compared with an age-matched control group of 12 boys to examine mechanisms that adapt the grip force at the digit-object interface in a precision grip task. An experimental grip object equipped...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/s0028-3932(00)00132-9
更新日期：2001-01-01 00:00:00
abstract：:The direct access model of hemispheric asymmetry was tested in a letter reflection (normal of reflected) judgement task. In the baseline condition letters were presented in their upright orientation, and reaction times were faster to letters presented in the right visual field than to those presented in the left visua...
journal_title：Neuropsychologia
pub_type： 临床试验,杂志文章
doi：10.1016/0028-3932(88)90037-1
更新日期：1988-01-01 00:00:00
abstract：:Hemispheric asymmetries in retarded and normal children were examined in dichotic tests which followed extensive auditory-discrimination training and which required non-verbal responses to digits or words. Mean right-ear advantages were smaller for the retarded group than for the normal group. However, most retarded c...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/0028-3932(83)90103-3
更新日期：1983-01-01 00:00:00
