Abstract:
:Using the simple argument based on irreversible thermodynamics and the Gouy-Chapman theory of the double layer, we show that the equilibrium distribution of charged lipid molecules between the two surfaces of a bilayer is asymmetric if the two solutions bathing the surfaces have the same ionic strength but contain ions of different valencies. For example, if one bathing solution contains 0.10 M NaCl and the other contains 0.70 M NaCl and 0.10 M CaCl2, the ratio of charged lipid molecules of the two surfaces in a membrane that contains 50% total negative lipids is 1.46, leading to a transbilayer potential of 18 mV. A complete set of such numerical results is presented in four figures.
journal_name
Biophys Jjournal_title
Biophysical journalauthors
McQuarrie DA,Mulás Pdoi
10.1016/S0006-3495(77)85629-4subject
Has Abstractpub_date
1977-02-01 00:00:00pages
103-9issue
2eissn
0006-3495issn
1542-0086pii
S0006-3495(77)85629-4journal_volume
17pub_type
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