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Carcinoma of vagina 10 or more years following pelvic irradiation therapy.

Abstract：

:Gynecologic cancer records of 4,238 patients treated between 1956 and 1974 were reviewed. Sixteen patients developed noeplasia in the cervix or vagina 10 or more years following pelvic irradiation. Three patients had squamous carcinoma in situ; the other 13 patients had invasive squamous cancer involving the upper vagina. Only 1.26 per cent of invasive carcinoma of the cervix treated by radiation therapy from 1956 to 1966 presented with a late or recurrent or new primary tumor involving the vagina or cervix 10 or more years after primary treatment. The authors conclude that the risk of developing radiation-induced carcinoma in the upper vagina or cervix following pelvic irradiation is low. Follow-up Pap smears are indicated for all patients treated for cervical or vaginal malignancies by radiation therapy in order to detect vaginal neoplasia as well as recurrent carcinoma of the cervix.

journal_name

Am J Obstet Gynecol

journal_title

American journal of obstetrics and gynecology

authors

Pride GL,Buchler DA

doi

10.1016/0002-9378(77)90445-8

subject

Has Abstract

pub_date

1977-03-01 00:00:00

pages

513-7

issue

5

eissn

0002-9378

issn

1097-6868

pii

0002-9378(77)90445-8

journal_volume

127

pub_type

杂志文章

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