Uterine artery embolization vs hysterectomy in the treatment of symptomatic uterine fibroids: 5-year outcome from the randomized EMMY trial.

Abstract:

OBJECTIVE:The purpose of this study was to compare clinical outcome and health related quality of life (HRQOL) 5 years after uterine artery embolization (UAE) or hysterectomy in the treatment of menorrhagia caused by uterine fibroids. STUDY DESIGN:Patients with symptomatic uterine fibroids who were eligible for hysterectomy were assigned randomly 1:1 to hysterectomy or UAE. Endpoints after 5 years were reintervention rates, menorrhagia, and HRQOL measures that were assessed by validated questionnaires. RESULTS:Patients were assigned randomly to UAE (n = 88) or hysterectomy (n = 89). Five years after treatment 23 of 81 UAE patients (28.4%) had undergone a hysterectomy because of insufficient improvement of complaints (24.7% after successful UAE). HRQOL measures improved significantly and remained stable until the 5-year follow-up evaluation, with no differences between the groups. UAE had a positive effect both on urinary and defecation function. CONCLUSION:UAE is a well-established alternative to hysterectomy about which patients should be counseled.

journal_name

Am J Obstet Gynecol

authors

van der Kooij SM,Hehenkamp WJ,Volkers NA,Birnie E,Ankum WM,Reekers JA

doi

10.1016/j.ajog.2010.01.049

subject

Has Abstract

pub_date

2010-08-01 00:00:00

pages

105.e1-13

issue

2

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(10)00079-7

journal_volume

203

pub_type

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