Alterations of L- and M-cone driven ERGs in cone and cone-rod dystrophies.

Abstract:

:To study the L- and M-cone pathways and their interactions in patients with cone and cone-rod dystrophies, ERG responses were measured to stimuli which modulated exclusively the L- or the M-cones, or the two simultaneously. The L- and M-cone driven ERG amplitudes were considerably reduced in the patients. The mean phases of the L-cone driven ERGs in the patients lagged those of normals significantly, whereas the mean M-cone driven ERGs were significantly phase advanced resulting in a substantial phase difference between the two ERG responses. These phase changes in the L- and M-cone driven responses in the patients cannot be detected with standard ERG techniques.

journal_name

Vision Res

journal_title

Vision research

authors

Scholl HP,Kremers J

doi

10.1016/s0042-6989(03)00411-5

subject

Has Abstract

pub_date

2003-10-01 00:00:00

pages

2333-44

issue

22

eissn

0042-6989

issn

1878-5646

pii

S0042698903004115

journal_volume

43

pub_type

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