Abstract:
:To study the L- and M-cone pathways and their interactions in patients with cone and cone-rod dystrophies, ERG responses were measured to stimuli which modulated exclusively the L- or the M-cones, or the two simultaneously. The L- and M-cone driven ERG amplitudes were considerably reduced in the patients. The mean phases of the L-cone driven ERGs in the patients lagged those of normals significantly, whereas the mean M-cone driven ERGs were significantly phase advanced resulting in a substantial phase difference between the two ERG responses. These phase changes in the L- and M-cone driven responses in the patients cannot be detected with standard ERG techniques.
journal_name
Vision Resjournal_title
Vision researchauthors
Scholl HP,Kremers Jdoi
10.1016/s0042-6989(03)00411-5subject
Has Abstractpub_date
2003-10-01 00:00:00pages
2333-44issue
22eissn
0042-6989issn
1878-5646pii
S0042698903004115journal_volume
43pub_type
杂志文章相关文献
VISION RESEARCH文献大全abstract::A simple electrophysiological method is described for determining the effective optical density of the intracellular pupil mechanism of insect photoreceptor cells. The method depends on the fact that the photoreceptors can not only be illuminated in the normal, orthodromic way, but also antidromically, i.e. from the b...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(90)90178-n
更新日期:1990-01-01 00:00:00
abstract::Neuroimaging studies have shown that the visual cortex of visually impaired humans is active during tactile tasks. We sought to determine if this cross-modal activation in the primary visual cortex is correlated with vision loss in individuals with retinitis pigmentosa (RP), an inherited degenerative photoreceptor dis...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2014.10.015
更新日期:2015-06-01 00:00:00
abstract::In the natural world, a binocular discrepancy of luminance can signal a glossy surface. Using a spatial forced choice task, we have measured the ability of subjects to detect binocular luminance disparities. We show that the detection of binocular luminance disparity shares several basic psychophysical features with t...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2009.05.001
更新日期:2009-07-01 00:00:00
abstract::Previous psychophysical studies have revealed that shape similarity can affect apparent motion correspondence. Such results however, do not specify the level of representation, at which shape similarity is defined. We sought to understand this question by using a 2 x 2 competitive apparent motion paradigm. We manipula...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(94)90322-0
更新日期:1994-08-01 00:00:00
abstract::Although pictorial illusions have been used to study perception for a long time, the effects of such displays on the visual control of actions has recently been the matter of some debate. Evidence from a re-analysis of an earlier study is presented that suggests pictorial displays can exert opposite effects on percept...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/s0042-6989(00)00056-0
更新日期:2000-01-01 00:00:00
abstract::We compared sensitivity to first-order versus second-order local motion in patients treated for dense central congenital cataracts in one or both eyes. Amplitude modulation thresholds were measured for discriminating the direction of motion of luminance-modulated (first-order) and contrast modulated (second-order) hor...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2004.11.019
更新日期:2005-10-01 00:00:00
abstract::The present paper reports results of a dual task study in which two locations were endogenously cued as possible target locations, while only one eye movement had to be executed. During the cue period, letters were briefly presented at the saccade goals and at no-saccade goals. Results show that performance was better...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2005.02.002
更新日期:2005-07-01 00:00:00
abstract::After hatching, larvae of coral reef fishes experience a pelagic phase during which they are diurnal planktivores. It has been suggested that ultraviolet (UV) vision is beneficial for the detection of planktonic prey. Aims were therefore to investigate whether ocular media of pre-settlement reef fish differ from those...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2007.05.014
更新日期:2007-08-01 00:00:00
abstract::We measured two- and three-line spatial interval and alignment thresholds for a wide range of separations and eccentricities. In order to avoid confounding the role of separation and eccentricity, the test lines were presented on iso-eccentric arcs, with radii between 0.625 and 10 deg. The iso-eccentric paradigm allow...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(90)90068-v
更新日期:1990-01-01 00:00:00
abstract::We applied new methods for canine eye-movement recording to the study of achiasmatic mutant Belgian Sheepdogs, documenting their nystagmus waveforms and comparing them to humans with either congenital nystagmus (CN) alone or in conjunction with achiasma. A sling apparatus with head restraints and infrared reflection w...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/s0042-6989(97)00337-4
更新日期:1998-06-01 00:00:00
abstract::Although color-opponent neurons appear to subserve color vision, precisely how these cells encode hue is still not clear. Single-unit, extracellular recordings from the rainbow trout optic tectum were made in order to examine the possible role of action potential timing in coding chromatic stimuli. We found that color...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/s0042-6989(99)00058-9
更新日期:1999-08-01 00:00:00
abstract::A number of recent studies have suggested that the "intersection of constraints" model of two dimensional motion perception, put forward by Adelson and Movshon [(1982) Nature, 300, 523-525], is incomplete. Evidence has been mounting that there is a second two-dimensional motion sensitive mechanism which is monocular a...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(94)90083-3
更新日期:1994-12-01 00:00:00
abstract::The factors potentially determining the dynamics of horizontal cell (HC) responses are: (1) the rate of transmitter release (including its transient component) and removal; (2) the voltage non-linearity of HC non-synaptic membrane combined with its capacitance; and (3) the dynamics of feedback from HCs to photorecepto...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/s0042-6989(96)00130-7
更新日期:1996-12-01 00:00:00
abstract::Glutamate transporters in the tiger salamander retina were studied by autoradiographic and intracellular recording techniques. When the retina was incubated with 15 microM L-[3H]glutamate, photoreceptors and Muller cells were labeled, indicating that these cells had high-affinity glutamate uptake transporters. A much ...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/s0042-6989(96)00231-3
更新日期:1997-04-01 00:00:00
abstract::How does the visual system represent the ensemble statistics of visual objects? This question has received intense interest in vision research, yet most studies have focused on the extraction of mean statistics rather than its dispersion. This study focuses on another aspect of ensemble statistics: the redundancy of t...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2012.11.013
更新日期:2013-01-15 00:00:00
abstract::Perceived contrast, contrast detection thresholds and contrast discrimination thresholds were measured in the presence and absence of surrounding patterns of a similar spatio-temporal makeup. In the foveal retina we found that the perceived contrast of the central pattern was reduced by the presence of the contrast su...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/s0042-6989(97)00379-9
更新日期:1998-06-01 00:00:00
abstract::The kinetics of synaptic transfer from photoreceptors to second order neurons have been determined in the retina of the snapping turtle. Analysis of the fluctuations resulting from the random release of cone transmitter molecules reveals that the action on postsynaptic channels of the depolarizing bipolar cells is pro...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(83)90083-4
更新日期:1983-01-01 00:00:00
abstract:PURPOSE:The mouse eye has potential to become an important model for studies on the genetic control of eye growth and myopia. However, no data are published on the development of its optical properties. We developed a paraxial schematic model of the growing eye for the most common laboratory mouse strain, the C57BL/6 m...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2004.03.011
更新日期:2004-01-01 00:00:00
abstract::We previously proposed a model for detecting local image velocity on the magnocellular visual pathway (Kawakami & Okamoto (1996) Vision Research, 36, 117-147). The model detects visual motion in two stages using the hierarchical network that includes component and pattern cells in area MT. To validate the model, we pr...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/s0042-6989(99)00073-5
更新日期:1999-10-01 00:00:00
abstract::Microspectrophotometry (MSP) shows rhodopsin highly concentrated (about 3.0 mmol/l) in rod outer segments (ROS). Calculation of the in vivo absorption spectrum of human rhodopsin from such data reveals a striking failure to agree with the action spectrum of human rod vision. Agreement is good between the spectral dist...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(87)90155-6
更新日期:1987-01-01 00:00:00
abstract::Refractive error, higher order aberrations (HOA), axial length (AL), anterior chamber depth (ACD) and average corneal radius of curvature were measured after cycloplegia from 166 emmetropic participants at the Sydney Myopia Study (SMS, 2004-2005, age 12.63 ± 0.48 years). Measurements were repeated approximately 5 year...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2014.10.003
更新日期:2014-12-01 00:00:00
abstract::Treatment of age-macular degeneration requires monthly intravitreal injections, which are costly and have serious risks. The objective of this study was to develop a novel intraocular implant for drug delivery. The capsule drug ring is a reservoir inserted in the lens capsule during cataract surgery, refillable and ca...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2009.10.013
更新日期:2010-03-31 00:00:00
abstract::In this study, we show that glutamate regulates the viability of cultured retinal cells upon transient glucose deprivation. At low concentrations (10-100 microM) glutamate decreased MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] reduction to about 50% of control and decreased intracellular ATP leve...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/s0042-6989(00)00309-6
更新日期:2001-03-01 00:00:00
abstract::It is commonly believed that objects viewed in certain contexts may be more or less salient. Measurements of salience have usually relied on asking observers "How much does this object stand out against the background?". In this study, we measured the salience of objects by assessing the distraction they produce for s...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2005.01.013
更新日期:2005-06-01 00:00:00
abstract::A subject with an unually large cortical scotoma, leaving a 9 degrees hemifield of vision in each eye, showed improvement with practice in pointing to an oscillating target positioned within the scotoma. The practice effect transferred to low-contrast targets and to stationary ones, though oscillating targets were alw...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(82)90085-2
更新日期:1982-01-01 00:00:00
abstract::Seven models of human visual recognition from cognitive psychology, visual psychophysics and connectionism were compared. They were used to predict psychophysical classification data obtained via supervised learning with parametrised grey-level patterns (compound Gabor signals). Four sets of learning patterns, as well...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/s0042-6989(97)00396-9
更新日期:1998-08-01 00:00:00
abstract::The properties of small monochromatic targets as accommodative stimuli are not well understood. We used a dynamic optometer to record accommodation responses to monochromatic disc targets (1.0-27.3 min arc) and to a Maltese cross. Accommodation responded adequately to points as small as 13.6 min arc. The response to t...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2004.06.013
更新日期:2004-11-01 00:00:00
abstract::When two sinusoidal gratings of the same orientation and similar spatial frequency are summed, the resulting pattern has a periodic spatial variation or beat in contrast. Although the pattern contains no luminance modulation component at the beat frequency, it behaves in some respects as if it did: human observers for...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(89)90035-7
更新日期:1989-01-01 00:00:00
abstract::In a texture-segregation paradigm, subjects were asked to detect figures whose elements were segregated from background either because of temporal offset or because of differing orientations. Texture elements were either isoluminant or had high or low luminance contrast. At high luminance contrast, figures could be se...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/s0042-6989(97)00148-x
更新日期:1998-01-01 00:00:00
abstract::Unit responses susceptible to light stimulation of a small area on the frog's head were recorded in the deep encephalon of blinded specimens of Rana esculenta. The responses consisted of a spike discharge upon illumination. Using a threshold criterion the dark adaptation curves showed two parts, separated by a kink, t...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(82)90016-5
更新日期:1982-01-01 00:00:00