Abstract:
:Parry-Romberg syndrome (PRS) is a rare neurocutaneous disorder characterized by progressive facial hemiatrophy. In this study, 205 patients with PRS were surveyed using the Internet. Estimates of the frequency of limb involvement (19%), epilepsy (11%), and other clinical and etiologic features were obtained. There was a wide range of age at onset and considerable diagnostic overlap with scleroderma "en coup de sabre."
journal_name
Neurologyjournal_title
Neurologyauthors
Stone Jdoi
10.1212/wnl.61.5.674subject
Has Abstractpub_date
2003-09-09 00:00:00pages
674-6issue
5eissn
0028-3878issn
1526-632Xjournal_volume
61pub_type
杂志文章相关文献
NEUROLOGY文献大全abstract:OBJECTIVE:To describe the clinical features of cardiac injury associated with neurogenic pulmonary edema (NPE) in patients with acute subarachnoid hemorrhage (SAH). BACKGROUND:NPE is generally viewed as a form of noncardiogenic pulmonary edema related to massive sympathetic discharge. METHODS:Case series. RESULTS:We...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.44.5.815
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND:According to the International Classification of Headache Disorders (ICHD)-2, primary daily headaches unremitting from onset are classified as new daily-persistent headache (NDPH) only if migraine features are absent. When migraine features are present, classification is problematic. METHODS:We developed a ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e3181dad5de
更新日期:2010-04-27 00:00:00
abstract::Subacute encephalitis, characterized by demyelination, gliosis of the gray and white matter, focal necrosis, microglial nodules, atypical oligodendrocyte nuclei, and multinucleation of cells, was present in 27 of 30 (90%) autopsied patients with acquired immune deficiency syndrome (AIDS) or AIDS-related complex. Subac...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.37.4.562
更新日期:1987-04-01 00:00:00
abstract:BACKGROUND:Previous studies have suggested a variety of factors that may be associated with the presence of hippocampal formation (HF) atrophy in patients with complex partial seizures (CPS), including a history of complex or prolonged febrile seizures (FS), age at seizure onset, and epilepsy duration. OBJECTIVE:To de...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.52.1.132
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:To determine the surgical outcome and factors of predictive value in patients undergoing reoperation for intractable partial epilepsy. METHODS:The authors retrospectively studied the operative outcome in 64 consecutive patients who underwent reoperation for intractable partial epilepsy. Demographic data, res...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000147476.86575.a7
更新日期:2004-12-28 00:00:00
abstract::Generalized epilepsy with febrile seizures plus (GEFS+) is a clinically and genetically heterogeneous syndrome with childhood onset, characterized by febrile seizures (FS) and a variety of afebrile epileptic seizure types. The authors performed a mutational analysis of SCN1B on 74 unrelated probands with GEFS+, FS, or...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000080362.55784.1c
更新日期:2003-09-23 00:00:00
abstract:OBJECTIVE:To perform a double-blind, randomized study comparing efficacy and safety of daily and weekend prednisone in boys with Duchenne muscular dystrophy (DMD). METHODS:A total of 64 boys with DMD who were between 4 and 10 years of age were randomized at 1 of 12 centers of the Cooperative International Neuromuscula...
journal_title:Neurology
pub_type: 杂志文章,随机对照试验
doi:10.1212/WNL.0b013e318227b164
更新日期:2011-08-02 00:00:00
abstract::Symptoms in patients with demyelinating disorders are associated with 3 important conduction abnormalities: complete conduction block, rate-dependent conduction block, and slowed impulse conduction. The recent observation that the electrogenic Na/K pump causes the nerve membrane hyperpolarization responsible for rate-...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.39.10.1364
更新日期:1989-10-01 00:00:00
abstract::We report the clinical and neuroimaging findings of a mother and daughter with seizure disorders and band heterotopias seen on magnetic resonance imaging studies. These clinicoradiologic findings simulate those for a diagnosis of tuberous sclerosis complex. Clinicians should be aware of this migrational anomaly and it...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.43.7.1424
更新日期:1993-07-01 00:00:00
abstract::Thyrotropin-releasing hormone has been reported to increase strength in patients with amyotrophic lateral sclerosis (ALS). DN-1417 is an analog of thyrotropin-releasing hormone, which has less endocrinologic activity, but more anterior horn cell stimulating effect (with no "autorefractory state"). However, 2 mg DN-141...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.37.4.715
更新日期:1987-04-01 00:00:00
abstract:OBJECTIVE:We aimed to assess sensitivity and specificity of the updated criteria for behavioral variant frontotemporal dementia (bvFTD) based on a large autopsy-confirmed cohort of patients with dementia. METHODS:Two hundred thirty-nine consecutive pathologically confirmed dementia patients, clinically assessed in a s...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e318292a342
更新日期:2013-05-14 00:00:00
abstract:OBJECTIVE:In multiple sclerosis (MS), the aim of therapies is to prevent the accumulation of irreversible disability. This is difficult to assess given the short time course of clinical trials. MRI markers and relapses are often used as surrogate of disability in MS studies, but their validity remains controversial. We...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e31823648b9
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:To determine the diagnostic accuracy and prognostic value of ¹⁸FDG-PET in a recent series of patients operated for intractable partial epilepsy associated with histologically proven Taylor-type focal cortical dysplasia (TTFCD) and negative MRI. METHODS:Of 23 consecutive patients (12 male, 7-38 years old) wit...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e31820203a9
更新日期:2010-12-14 00:00:00
abstract::Salla disease is a lysosomal storage disorder associated with increased urinary excretion of free sialic acid. The main clinical features in 34 patients were severe psychomotor retardation of early onset, ataxia, athetosis, rigidity, spasticity, and impaired speech. Growth retardation, thick calvarium, and exotropia w...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.33.1.57
更新日期:1983-01-01 00:00:00
abstract::We examined serum-mediated cytotoxicity on cultured rat oligodendrocytes, using serum from patients with acute or chronic progressive multiple sclerosis and normal controls. We found heat-labile serum factors in serum from MS and also in controls. The cytotoxic effects of MS and normal sera were not restored by adding...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.36.2.276
更新日期:1986-02-01 00:00:00
abstract:OBJECTIVE:To determine the role of oxidative stress in mediating HIV dementia and to identify novel therapeutic compounds that may block this oxidative stress. METHODS:Brain tissue from patients with HIV encephalitis and macaques with simian immune deficiency virus encephalitis was immunostained for lipid peroxidation...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000042048.85204.3d
更新日期:2003-01-28 00:00:00
abstract:OBJECTIVE:To determine black-white differences in 1-year recurrent stroke and 30-day case fatality after a recurrent stroke in older US adults. METHODS:We conducted a retrospective cohort study using a 5% random sample of Medicare beneficiaries with fee-for-service health insurance coverage who were hospitalized for i...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000006467
更新日期:2018-11-06 00:00:00
abstract::The clinical and angiographic correlations of small deep infarcts seen on computed tomography (CT) scan were studied in 297 consecutive patients. Some of these showed the features described by Fisher as part of the lacunar syndrome. In a large number, a source of emboli from either a cardiac or a carotid source was hi...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.30.10.1090
更新日期:1980-10-01 00:00:00
abstract::A 61-year-old woman presented with two paraneoplastic neurologic disorders--Lambert-Eaton myasthenic syndrome (LEMS) and subacute cerebellar degeneration (SCD)--that antedated the diagnosis of small-cell carcinoma of the lung by 15 months. Plasmapheresis initiated before the identification of the tumor had a beneficia...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.41.10.1682
更新日期:1991-10-01 00:00:00
abstract:OBJECTIVE:To analyze the spectrum and mechanisms of cutaneous adverse events (AEs) in patients with multiple sclerosis treated with daclizumab high-yield process (DAC-HYP). METHODS:A total of 31 participants in an institutional review board-approved open-label phase I study of DAC-HYP (NCT01143441) were prospectively ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000002417
更新日期:2016-03-01 00:00:00
abstract::We have studied one family of a pedigree in which bulbospinal muscular atrophy and protanopia were segregated. Genotypes for these disorders were obtained on three generations, and the maximum likelihood estimate of recombination fraction was 0.4 with the lod score method. The results indicated that the two loci are n...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.37.6.1019
更新日期:1987-06-01 00:00:00
abstract:OBJECTIVE:To study the accuracy of the ABCD2 score in predicting early stroke risk following TIA and to model post-test probability of stroke for varying cutoff scores and baseline stroke risk. METHODS:Medline, PubMed, Embase, conference proceedings, and manuscript references up to October 2010 were searched for studi...
journal_title:Neurology
pub_type: 杂志文章,meta分析
doi:10.1212/WNL.0b013e31825f9d02
更新日期:2012-09-04 00:00:00
abstract:OBJECTIVE:To develop and evaluate a model for staging cortical amyloid deposition using PET with high generalizability. METHODS:Three thousand twenty-seven individuals (1,763 cognitively unimpaired [CU], 658 impaired, 467 with Alzheimer disease [AD] dementia, 111 with non-AD dementia, and 28 with missing diagnosis) fr...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000010256
更新日期:2020-09-15 00:00:00
abstract:OBJECTIVE:To test the hypothesis that brain pathology is associated with total daily physical activity proximate to death in older adults. METHODS:We studied brain autopsies from 428 decedents of the Rush Memory and Aging Project. The quantity of all physical activity was measured continuously for up to 10 days with a...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000005552
更新日期:2018-05-22 00:00:00
abstract::We studied acetaminophen sulfation, plasma sulfate levels, and the activity of sulfotransferase in blood platelets in patients with Parkinson's disease, Huntington's disease, and in controls and did not find any abnormality in the patient groups, independent of the use of medication. ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.43.7.1373
更新日期:1993-07-01 00:00:00
abstract:OBJECTIVE:To determine the diagnostic accuracy and clinical utility of electromagnetic source imaging (EMSI) in presurgical evaluation of patients with epilepsy. METHODS:We prospectively recorded magnetoencephalography (MEG) simultaneously with EEG and performed EMSI, comprising electric source imaging, magnetic sourc...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000006877
更新日期:2019-02-05 00:00:00
abstract::The excitability of the corticospinal system was studied in 23 healthy subjects in sleep stages NREM2, NREM4, REM, and wakefulness using transcranial magnetic stimulation. Assessment of motor thresholds, stimulus-response curves, and latencies of motor evoked potentials shows activation of the fast-conducting corticos...
journal_title:Neurology
pub_type: 临床试验,杂志文章
doi:10.1212/01.wnl.0000038762.11894.da
更新日期:2002-12-24 00:00:00
abstract:OBJECTIVE:We prospectively investigated the role of depressive symptoms (DS) on all-cause dementia in a population with small vessel disease (SVD), considering onset age of DS and cognitive performance. METHODS:The RUN DMC study (Radboud University Nijmegen Diffusion Tensor and Magnetic Resonance Cohort) is a prospect...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000003089
更新日期:2016-09-13 00:00:00
abstract::We applied quantitative methods to measure extrapyramidal signs in 50 Alzheimer's disease (AD) patients and 40 age-matched control subjects. We measured tremor using accelerometers, bradykinesia using computer-detected reaction times (RTs) and movement times (MTs), and rigidity using a strain gauge linked to a movable...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.43.3_part_1.500
更新日期:1993-03-01 00:00:00
abstract::We studied four patients with neurologic disorders of the lumbosacral plexus. Except for location of symptoms, the disorder confirmed to criteria established for the clinical diagnosis of brachial plexus neuritis. Acute onset of pain in one or both legs was followed by weakness, loss of stretch reflexes, and sometimes...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.31.4.470
更新日期:1981-04-01 00:00:00