Premature pulmonary valve opening.

abstract：BACKGROUND:Type 2 diabetes (DM-2) and impaired glucose metabolism (IGM) are associated with an increased cardiovascular disease risk. In nondiabetic individuals, increased arterial stiffness is an important cause of cardiovascular disease. Associations between DM-2 and IGM and arterial stiffness have not been systemati...

journal_title：Circulation

authors： Henry RM,Kostense PJ,Spijkerman AM,Dekker JM,Nijpels G,Heine RJ,Kamp O,Westerhof N,Bouter LM,Stehouwer CD,Hoorn Study.

更新日期：2003-04-29 00:00:00

abstract：BACKGROUND:Myocardial ischemia is considered to be a possible stimulus for development of the coronary collateral circulation. We therefore hypothesized that chronic reduction of myocardial oxygen demand to lessen ischemia would attenuate coronary collateral development over an 8-week period using left circumflex coron...

journal_title：Circulation

authors： Symons JD,Pitsillides KF,Longhurst JC

更新日期：1992-08-01 00:00:00

abstract：:This study examined quantitative regional myocardial perfusion (RMP) measured by the washout of 133Xe at rest and after an isoproterenol challenge in 50 patients (group I) studied 8 to 14 days after they underwent saphenous vein bypass grafting to the left coronary artery, and compared this with RMP measured in the na...

journal_title：Circulation

authors： Schmidt DH,Blau FM,Hendrix LJ,Kamath ML,Ray G

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:Although global ischemia induces troponin I (TnI) degradation, regional ischemia does not. We hypothesized that this disparity is related to preload-induced proteolysis, which varies as a function of the amount of myocardium at risk of ischemia. METHODS AND RESULTS:Isolated rat hearts were buffer-perfused a...

journal_title：Circulation

authors： Feng J,Schaus BJ,Fallavollita JA,Lee TC,Canty JM Jr

更新日期：2001-04-24 00:00:00

abstract：BACKGROUND:In patients with mitral regurgitation, surgical intervention produces immediate improvement in symptoms, but the long-term incidence and significance of postoperative congestive heart failure are unknown. METHODS AND RESULTS:The long-term outcome of 576 operative survivors of surgical correction of pure mit...

journal_title：Circulation

authors： Enriquez-Sarano M,Schaff HV,Orszulak TA,Bailey KR,Tajik AJ,Frye RL

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Functional benefit in heart failure due to idiopathic dilated cardiomyopathy has been observed after beta-blockade, but improvement in survival has not been established in a large-scale randomized trial. This was the main objective of the Cardiac Insufficiency Bisoprolol Study (CIBIS). METHODS AND RESULTS:S...

journal_title：Circulation

authors：

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Polymorphonuclear leukocytes, particularly neutrophils, are important mediators of ischemia/reperfusion-induced myocardial and coronary vascular injury. The selectin family of glycoprotein receptors mediates neutrophil "rolling," a loose, transient adhesion to the coronary endothelium that precedes the firme...

journal_title：Circulation

authors： Gill EA,Kong Y,Horwitz LD

更新日期：1996-08-01 00:00:00

abstract：:Neutrophil activation and infiltration into the ischemic myocardium after reperfusion may limit the amount of salvageable myocardium (reperfusion injury). The effects of intravenous perfluorochemicals (Fluosol-DA) on infarct size, ventricular contractility, and neutrophil function were assessed in an occlusion-reperfu...

journal_title：Circulation

authors： Bajaj AK,Cobb MA,Virmani R,Gay JC,Light RT,Forman MB

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Sugar-sweetened beverage consumption is associated with weight gain and risk of type 2 diabetes mellitus. Few studies have tested for a relationship with coronary heart disease (CHD) or intermediate biomarkers. The role of artificially sweetened beverages is also unclear. METHODS AND RESULTS:We performed an...

journal_title：Circulation

authors： de Koning L,Malik VS,Kellogg MD,Rimm EB,Willett WC,Hu FB

更新日期：2012-04-10 00:00:00

abstract：BACKGROUND:Congenital long-QT syndrome (LQTS) is a primary arrhythmogenic syndrome stemming from perturbed cardiac repolarization. LQTS, which affects approximately 1 in 3000 persons, is 1 of the most common causes of autopsy-negative sudden death in the young. Since the sentinel discovery of cardiac channel gene mutat...

journal_title：Circulation

authors： Vatta M,Ackerman MJ,Ye B,Makielski JC,Ughanze EE,Taylor EW,Tester DJ,Balijepalli RC,Foell JD,Li Z,Kamp TJ,Towbin JA

更新日期：2006-11-14 00:00:00

abstract：BACKGROUND:Low endothelial shear stress (ESS) promotes the development of atherosclerosis; however, its role in the progression of atherosclerotic plaques and evolution to inflamed high-risk plaques has not been studied. Our hypothesis was that the lowest values of ESS are responsible for the development of high-risk c...

journal_title：Circulation

authors： Chatzizisis YS,Jonas M,Coskun AU,Beigel R,Stone BV,Maynard C,Gerrity RG,Daley W,Rogers C,Edelman ER,Feldman CL,Stone PH

更新日期：2008-02-26 00:00:00

abstract：:Resting hemodynamics improve during vasodilator administration in patients, with congestive heart failure (CHF), but the effects of these agents on exercise is unknown. Twenty-two patients with class II or III CHF performed bicycle exercise to symptomatic maximum before and 90 minutes after random double-blind adminis...

journal_title：Circulation

authors： Franciosa JA,Cohn JN

更新日期：1979-06-01 00:00:00

abstract：BACKGROUND:To simplify extensive primary repair of the thoracic aorta in acute type A aortic dissection, we developed the open triple-branched stent graft placement technique. The early results of this new technique are reported. METHODS AND RESULTS:Between June 2008 and November 2009, 30 patients with acute Stanford ...

journal_title：Circulation

authors： Chen LW,Dai XF,Lu L,Zhang GC,Cao H

更新日期：2010-10-05 00:00:00

abstract：BACKGROUND:In vitro experiments have shown that holmium laser energy can effectively ablate even calcified plaque in human arterial vessels. Because high-energy densities from holmium lasers can easily be transmitted through quartz fibers, this solid-state laser has been suggested as an alternative intraluminal treatme...

journal_title：Circulation

authors： Hassenstein S,Hanke H,Kamenz J,Oberhoff M,Hanke S,Riessen R,Haase KK,Betz E,Karsch KR

更新日期：1992-11-01 00:00:00

abstract：:The effectiveness of intra-aortic balloon pumping in augmenting ventricular performance during acute myocardial ischemic syndromes was determined by noninvasive multigated cardiac blood pool imaging. Nine patients with unstable angina refractory to medical therapy and nine patients with acute myocardial infarction com...

journal_title：Circulation

authors： Nichols AB,Pohost GM,Gold HK,Leinbach RC,Beller GA,McKusick KA,Strauss HW,Buckley MJ

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:Apoptosis contributes to cell loss after ischemia/reperfusion injury in the heart. This study describes the time course and level of apoptosis in different cell types in the intact heart during ischemia/reperfusion injury. METHODS AND RESULTS:Isolated Langendorff-perfused rat hearts were subjected to perfus...

journal_title：Circulation

authors： Scarabelli T,Stephanou A,Rayment N,Pasini E,Comini L,Curello S,Ferrari R,Knight R,Latchman D

更新日期：2001-07-17 00:00:00

abstract：BACKGROUND:Previous studies have established that bone marrow-derived endothelial progenitor cells (EPCs) are present in the systemic circulation. In the current study, we investigated the hypothesis that gene transfer can be used to achieve phenotypic modulation of EPCs. METHODS AND RESULTS:In vitro, ex vivo murine v...

journal_title：Circulation

authors： Iwaguro H,Yamaguchi J,Kalka C,Murasawa S,Masuda H,Hayashi S,Silver M,Li T,Isner JM,Asahara T

更新日期：2002-02-12 00:00:00

abstract：:Total body surface maps from 15 subjects with left bundle branch block and normal axis (LBBB-NA) and 10 subjects with left bundle branch block and left axis (LBBB-LA) were analyzed and compared with maps from normal subjects. In 19 of the 25 subjects with LBBB, the timing of early upper sternal positivity was similar ...

journal_title：Circulation

authors： Sohi GS,Flowers NC,Horan LG,Sridharan MR,Johnson JC

更新日期：1983-03-01 00:00:00

abstract：BACKGROUND:One of the features of high-risk atherosclerotic plaques is a preponderance of macrophages. Experimental studies with hyperlipidemic rabbits have shown that ultrasmall superparamagnetic particles of iron oxide (USPIOs) accumulate in plaques with a high macrophage content and that this induces magnetic resona...

journal_title：Circulation

authors： Kooi ME,Cappendijk VC,Cleutjens KB,Kessels AG,Kitslaar PJ,Borgers M,Frederik PM,Daemen MJ,van Engelshoven JM

更新日期：2003-05-20 00:00:00

abstract：:Six instances of sudden death were recorded by Holter monitoring, which showed ventricular fibrillation in five and a bradyarrhythmia in one. Complex ventricular ectopic activity preceded cardiac arrest in five patients, including the one with the bradyarrhythmic arrest. Two patients with chronic bifascicular block ar...

journal_title：Circulation

authors： Nikolic G,Bishop RL,Singh JB

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND:Although early trials indicate the treatment of restenosis with radiation therapy is safe and effective, the long-term impact of this new technology has been questioned. The possibility of late untoward consequences, such as aneurysm formation, perforation, and accelerated vascular disease, is of significant...

journal_title：Circulation

authors： Teirstein PS,Massullo V,Jani S,Russo RJ,Cloutier DA,Schatz RA,Guarneri EM,Steuterman S,Sirkin K,Norman S,Tripuraneni P

更新日期：1999-01-19 00:00:00

abstract：:Emerging evidence indicates that etiology plays an essential role in the results of mitral valve repair. In an attempt to evaluate the possibilities and problems of repair in a rheumatic population, all consecutive patients treated between July 1988 and July 1990 were reviewed. Three hundred and four patients at risk ...

journal_title：Circulation

authors： Duran CM,Gometza B,De Vol EB

更新日期：1991-11-01 00:00:00

abstract：:In patients treated with sulfinpyrazone, an apparent reduction in the incidence of sudden death and presumed ventricular fibrillation has been reported. Using an intact animal model without microcirculatory thrombosis, we studied the effects of sulfinpyrazone on ischemic myocardium in 58 anesthetized dogs divided into...

journal_title：Circulation

authors： Moschos CB,Escobinas AJ,Jorgensen OB Jr,Regan TJ

更新日期：1981-07-01 00:00:00

abstract：:The patterns of aortic and tricuspid valve motion in 50 patients with mitral valve prolapse were analyzed by wide-angle, phased-array, two-dimensional echocardiography. Twelve patients (24%) had redundant aortic leaflets bulging into the left ventricular outflow tract during diastole. Eight of 12 patients had aortic r...

journal_title：Circulation

authors： Ogawa S,Hayashi J,Sasaki H,Tani M,Akaishi M,Mitamura H,Sano M,Hoshino T,Handa S,Nakamura Y

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:Venous thromboembolism can be a presenting symptom of cancer, but the association between lower limb arterial thrombosis and cancer is unknown. We therefore examined cancer risk and prognosis of cancer in patients with lower limb arterial thrombosis. METHODS:Using nationwide population-based Danish medical ...

journal_title：Circulation

authors： Sundbøll J,Veres K,Horváth-Puhó E,Adelborg K,Sørensen HT

更新日期：2018-08-14 00:00:00

abstract：:In 61 patients sinus node function was tested by programmed (sinoatrial conduction time, SACT) and overdrive atrial pacing (sinus node recovery time, SRT). In the control group (N = 20), mean sinus cycle length was 773 +/- 140.2 msec, mean absolute SRT 1044 +/- 215.8 msec [corrected SRT (CSRT) 270 +/- 112.5 msec; mean...

journal_title：Circulation

authors： Breithardt G,Seipel L,Loogen F

更新日期：1977-07-01 00:00:00

abstract：BACKGROUND:Prior small to modest-sized studies suggest a benefit of intravascular ultrasound (IVUS) guidance in noncomplex lesions. Whether IVUS guidance is associated with improved clinical outcomes after drug-eluting stent (DES) implantation in an unrestricted patient population is unknown. METHODS AND RESULTS:Asses...

journal_title：Circulation

authors： Witzenbichler B,Maehara A,Weisz G,Neumann FJ,Rinaldi MJ,Metzger DC,Henry TD,Cox DA,Duffy PL,Brodie BR,Stuckey TD,Mazzaferri EL Jr,Xu K,Parise H,Mehran R,Mintz GS,Stone GW

更新日期：2014-01-28 00:00:00

abstract：BACKGROUND:Anthracyclines are the most effective drugs available in the treatment of neoplastic diseases; however, they have profound consequences on the structure and function of the heart, which over time cause a cardiomyopathy that leads to congestive heart failure. METHODS AND RESULTS:Administration of doxorubicin...

journal_title：Circulation

authors： De Angelis A,Piegari E,Cappetta D,Marino L,Filippelli A,Berrino L,Ferreira-Martins J,Zheng H,Hosoda T,Rota M,Urbanek K,Kajstura J,Leri A,Rossi F,Anversa P

更新日期：2010-01-19 00:00:00

abstract：:We used a canine preparation of experimental infarction to study the natural course of echocardiographically defined regional wall motion abnormalities in the 6 weeks after acute coronary ligation. Eight dogs underwent serial short-axis echocardiographic evaluation and microsphere blood flow determinations at control,...

journal_title：Circulation

authors： Gibbons EF,Hogan RD,Franklin TD,Nolting M,Weyman AE

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:Factor Xa plays a central role in the generation of thrombin, making it a novel target for treatment of arterial thrombosis. Fondaparinux is a synthetic factor Xa inhibitor that has been shown to be superior to standard therapies for the prevention of venous thrombosis. We performed a randomized trial to det...

journal_title：Circulation

authors： Mehta SR,Steg PG,Granger CB,Bassand JP,Faxon DP,Weitz JI,Afzal R,Rush B,Peters RJ,Natarajan MK,Velianou JL,Goodhart DM,Labinaz M,Tanguay JF,Fox KA,Yusuf S,ASPIRE Investigators.

更新日期：2005-03-22 00:00:00