Contractile function of right ventricular papillary muscle after left ventricular infarction in rats: effects of early and late inhibition of angiotensin converting enzyme.

abstract：:The pharmacokinetics of glyceryl trinitrate are still not completely understood. The substance disappears rapidly from plasma largely by extrahepatic mechanisms. It is converted in glyceryl dinitrates and glyceryl mononitrates. After transdermal application of a controlled delivery system, plasma concentrations of gly...

journal_title：European heart journal

authors： Bogaert MG

更新日期：1988-01-01 00:00:00

abstract：:The effect of 24 weeks of treatment with simvastatin, a new HMG coenzyme A reductase inhibitor (dosages of 20 and 40 mg day-1) on serum lipid, lipoprotein and apolipoprotein A-I and B concentrations as well as safety parameters and subjective side effects were studied in 11 patients with familial (FH) and 10 patients ...

journal_title：European heart journal

authors： Mölgaard J,von Schenck H,Olsson AG

更新日期：1988-05-01 00:00:00

abstract：:From January 1978 to August 1983, 41 prosthetic valve thromboses in 34 patients were operated upon in our service. They comprised 15 aortic, 25 mitral and one tricuspid valve thromboses. Seven patients had massive thrombus with dysfunction of the prosthesis; others had small and disseminated thrombi on their prosthesi...

journal_title：European heart journal

authors： Pavie A,Bors V,Baud F,Gandjbakhch I,Cabrol C

更新日期：1984-10-01 00:00:00

abstract：AIMS:Three methods are used to identify dysglycaemia: fasting plasma glucose (FPG), 2-h post-load plasma glucose (2hPG) from the oral glucose tolerance test (OGTT), and glycated haemoglobin A1c (HbA1c). The aim was to describe the yield and concordance of FPG, HbA1c, and 2hPG alone, or in combination, to identify dysgl...

journal_title：European heart journal

authors： Gyberg V,De Bacquer D,Kotseva K,De Backer G,Schnell O,Sundvall J,Tuomilehto J,Wood D,Rydén L,EUROASPIRE IV Investigators.

更新日期：2015-05-14 00:00:00

abstract：:In 103 hearts with various forms of cardiac muscle hypertrophy the following parameters were estimated: diameter, length, volume, density and number of myocytes, and density of myocyte nuclei. The values of all histometric parameters correlated well with left ventricular (LV) weight up to 350 g. In heavier hearts thes...

journal_title：European heart journal

authors： Grajek S,Lesiak M,Pyda M,Zajac M,Paradowski S,Kaczmarek E

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Microvascular obstruction (MVO) following primary percutaneous coronary intervention (PPCI) treatment of ST-segment elevation myocardial infarction (STEMI) contributes to infarct expansion, left ventricular (LV) remodelling, and worse clinical outcomes. The REFLO-STEMI trial tested whether intra-coronary (IC...

journal_title：European heart journal

authors： Nazir SA,McCann GP,Greenwood JP,Kunadian V,Khan JN,Mahmoud IZ,Blackman DJ,Been M,Abrams KR,Shipley L,Wilcox R,Adgey AA,Gershlick AH

更新日期：2016-06-21 00:00:00

abstract：:Arbutamine (Gensia, Inc., San Diego, CA) is a newly-developed sympathomimetic agent specifically designed for cardiovascular stress testing. It has been successfully used for the detection of coronary artery disease in conjunction with electrocardiography, echocardiographic and radionuclide techniques. Arbutamine incr...

journal_title：European heart journal

authors： Armstrong WF,Bach DS

更新日期：1995-11-01 00:00:00

abstract：:To determine the effects of acute myocardial infarction on the extent and distribution of mural stress on surviving myocardial tissue, coronary artery occlusion was surgically produced in rats. Following haemodynamic measurements in vivo, the characteristics of cardiac anatomy were determined and found to consist of a...

journal_title：European heart journal

authors： Anversa P,Reiss K,Kajstura J,Cheng W,Li P,Sonnenblick EH,Olivetti G

更新日期：1995-12-01 00:00:00

abstract：:A new European Heart Journal, Cardiovascular Pharmacotherapy, was launched at the ESC Congress 2014 in Barcelona and begins publication in February 2014. ...

journal_title：European heart journal

authors： Ozcan J

更新日期：2014-09-07 00:00:00

abstract：AIMS:Valve compliance might determine the onset of symptoms better than resting measures of aortic stenosis. This study compared valve compliance measured by dobutamine stress echocardiography with resting haemodynamic variables against the end-point of symptoms at low workload during exercise testing. METHODS AND RES...

journal_title：European heart journal

authors： Das P,Rimington H,Smeeton N,Chambers J

更新日期：2003-07-01 00:00:00

abstract：:The feasibility of transcatheter laser coagulation of atrial myocardium was tested in a canine model by using a combined electrode-laser catheter. In 17 anaesthetized beagles a total of 264 lesions, 12-19 per dog, and 3-5 in each area were produced in: (1) the lateral walls, (2) the posterior right atrial walls, (3) t...

journal_title：European heart journal

authors： Weber HP,Heinze A,Enders S,Ruprecht L,Unsöld E

更新日期：1994-07-01 00:00:00

abstract：AIMS:Cardiac biomarkers are routinely elevated after uncomplicated cardiac surgery to levels considered diagnostic of myocardial infarction in ambulatory populations. We investigated the diagnostic power of electrocardiogram (ECG) and cardiac biomarker criteria to predict clinically relevant myocardial injury using ben...

journal_title：European heart journal

authors： Muehlschlegel JD,Perry TE,Liu KY,Nascimben L,Fox AA,Collard CD,Avery EG,Aranki SF,D'Ambra MN,Shernan SK,Body SC,CABG Genomics Investigators.

更新日期：2009-07-01 00:00:00

abstract：:The cytokine hypothesis presently suggests that an excessive production of pro-inflammatory cytokines, such as tumour necrosis factor alpha (TNF) and interleukin 6 (IL6), contributes to the pathogenesis of heart failure. The concept, successfully proved in genetically modified animal models, failed to translate to hum...

journal_title：European heart journal

authors： Lecour S,James RW

更新日期：2011-03-01 00:00:00

abstract：AIMS:Hitherto, sudden cardiac death in children (SCDc)-defined as sudden cardiac death (SCD) in the 1-18 years old-has been incompletely described in the general population. Knowledge on incidence rates, causes of death and symptoms prior to death is sparse and has been affected by reporting and referral bias. METHODS...

journal_title：European heart journal

authors： Winkel BG,Risgaard B,Sadjadieh G,Bundgaard H,Haunsø S,Tfelt-Hansen J

更新日期：2014-04-01 00:00:00

abstract：:In 16 male patients with heart failure (NYHA II-III), the influence of a single dose of 25 mg captopril on the carotid sinus baroreceptor reflex was examined. Blood pressure fell significantly by 11 +/- 1.7 mm Hg (P less than 0.001), whereas heart rate remained unchanged (85 +/- 3 vs. 83 +/- 3 beats min-1). Carotid si...

journal_title：European heart journal

authors： Osterziel KJ,Röhrig N,Dietz R,Manthey J,Hecht J,Kübler W

更新日期：1988-10-01 00:00:00

abstract：AIMS:The coefficient of variation is a popular measure for describing the amount of repeat variability present in ECG measurements from recording to recording. However, it can be misleading. The aim of the present study was to assess repeat variation (reclassification) in computer measured ECG criteria, i.e. positive t...

journal_title：European heart journal

authors： McLaughlin SC,Aitchison TC,Macfarlane PW

更新日期：1998-02-01 00:00:00

abstract：:A right atrial myxoma was detected by cross-sectional echocardiography in a 21-year-old woman with cutaneous lentiginosis. The lentigines were present mainly on the right side of the trunk. ...

journal_title：European heart journal

authors： Göksel S,Kural T

更新日期：1989-08-01 00:00:00

abstract：AIMS:Sudden unexplained death syndrome occurs in previously healthy South-east Asian young adults without any structural cause of death. The common electrocardiographic (ECG) change in sudden unexplained death syndrome survivors is right bundle branch block and ST elevations in leads V(1) to V(3), which are similar to ...

journal_title：European heart journal

authors： Sangwatanaroj S,Prechawat S,Sunsaneewitayakul B,Sitthisook S,Tosukhowong P,Tungsanga K

更新日期：2001-12-01 00:00:00

abstract：AIMS:Growth differentiation factor 11 and/or its homologue growth differentiation factor 8 (GDF11/8) reverses age-related cardiac hypertrophy and vascular ageing in mice. We investigated whether GDF11/8 associates with cardiovascular outcomes, left ventricular hypertrophy (LVH), or age in humans. METHODS AND RESULTS:W...

journal_title：European heart journal

authors： Olson KA,Beatty AL,Heidecker B,Regan MC,Brody EN,Foreman T,Kato S,Mehler RE,Singer BS,Hveem K,Dalen H,Sterling DG,Lawn RM,Schiller NB,Williams SA,Whooley MA,Ganz P

更新日期：2015-12-21 00:00:00

abstract：AIMS:Emerging evidence indicates that nuclear receptors play a critical regulatory role in cardiovascular physiology/pathology. Recently, farnesoid-X-receptor (FXR), a member of the metabolic nuclear receptor superfamily, has been demonstrated to be expressed in vascular cells, with important roles in vascular physiolo...

journal_title：European heart journal

authors： Pu J,Yuan A,Shan P,Gao E,Wang X,Wang Y,Lau WB,Koch W,Ma XL,He B

更新日期：2013-06-01 00:00:00

abstract：:Sudden cardiac death (SCD) accounts for approximately one-third of all deaths among patients with non-ischaemic cardiomyopathy (NICM). Implantable cardioverter-defibrillator (ICD) therapy has been the primary intervention for managing individuals at high risk for SCD. However, individual ICD trials in the NICM populat...

journal_title：European heart journal

authors： Pathak RK,Sanders P,Deo R

更新日期：2018-08-14 00:00:00

abstract：AIMS:The transversal distribution of coronary atherosclerotic plaques (AP) (myocardial vs pericardial) affects vessel remodelling. The aim of this study was to define the impact of transversal lesion distribution on vessel remodelling in proximal and distal coronary segments using a 3D intravascular ultrasound (IVUS) r...

journal_title：European heart journal

authors： Prati F,Arbustini E,Labellarte A,Sommariva L,Pawlowski T,Manzoli A,Pagano A,Motolese M,Boccanelli A

更新日期：2003-02-01 00:00:00

abstract：:AIMS More intense platelet-directed therapy for acute coronary syndrome (ACS) may increase bleeding risk. The aim of the current analysis was to determine the rate, clinical impact, and predictors of major and fatal bleeding complications in the PLATO study. METHODS AND RESULTS PLATO was a randomized, double-blind, ac...

journal_title：European heart journal

authors： Becker RC,Bassand JP,Budaj A,Wojdyla DM,James SK,Cornel JH,French J,Held C,Horrow J,Husted S,Lopez-Sendon J,Lassila R,Mahaffey KW,Storey RF,Harrington RA,Wallentin L

更新日期：2011-12-01 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) can be a rapidly progressive disorder and is associated with high rate of mortality, despite medical intervention. With the availability of effective therapy, early disease detection is an important strategic objective to improve treatment outcomes. Resting echocardiography is cur...

journal_title：European heart journal

authors： Lau EM,Manes A,Celermajer DS,Galiè N

更新日期：2011-10-01 00:00:00

abstract：AIMS:Our aim was to follow changes in myocardial function and physiology in patients awaiting coronary artery bypass surgery (CABG) and relate changes to post-revascularisation functional response. METHODS AND RESULTS:In 21 patients with CAD and LV dysfunction, myocardial glucose utilisation (MGU) and blood flow (MBF)...

journal_title：European heart journal

authors： Pitt M,Dutka D,Pagano D,Camici P,Bonser R

更新日期：2004-03-01 00:00:00

abstract：:I.S.A.M. was a prospective, placebo-controlled, double-blind multicentre trial of high-dose short-term intravenous streptokinase in acute myocardial infarction (AMI) within 6 h of the onset of symptoms. Determination of left ventricular ejection fraction (LVEF) by radionuclide ventriculography was performed 1 and 7 mo...

journal_title：European heart journal

authors： Voth E,Tebbe U,Schicha H,Neumann P,Schröder R,Neuhaus KL,Emrich D

更新日期：1990-10-01 00:00:00

abstract：:Severe primary mitral regurgitation (MR) has a poor outcome if left uncorrected. Successful mitral valve repair has the unique potential to restore normal life expectancy and is superior to valve replacement. Despite this, mitral repair is performed relatively infrequently and many patients with potentially reparable ...

journal_title：European heart journal

authors： Ray S,Chambers J,Gohlke-Baerwolf C,Bridgewater B

更新日期：2006-12-01 00:00:00

abstract：AIMS:Surgery in patients with infective endocarditis (IE) can be elective (upon completion of antibiotic treatment) or urgent (before antibiotic treatment has ended) when the clinical course is unfavourable. However, urgent surgery for left-sided endocarditis is associated with high mortality. The aims of this study we...

journal_title：European heart journal

authors： Revilla A,López J,Vilacosta I,Villacorta E,Rollán MJ,Echevarría JR,Carrascal Y,Di Stefano S,Fulquet E,Rodríguez E,Fiz L,San Román JA

更新日期：2007-01-01 00:00:00

abstract：:Both epidemiological studies and intervention trials support an important role of diet in reducing the risk of a variety of chronic diseases, including cardiovascular disease, and overall mortality. We discuss available evidence indicating that the generation of a pro-inflammatory milieu might be one mechanism through...

journal_title：European heart journal

authors： Esposito K,Giugliano D

更新日期：2006-01-01 00:00:00

abstract：AIMS:To investigate the efficacy and outcome of emergency percutaneous coronary interventions (PCI) in patients with stent thrombosis. METHODS AND RESULTS:Between 1995 and 2003, 6058 patients underwent bare-metal stent implantation, of which 95 (1.6%) patients suffered from stent thrombosis. The timing of stent thromb...

journal_title：European heart journal

authors： Wenaweser P,Rey C,Eberli FR,Togni M,Tüller D,Locher S,Remondino A,Seiler C,Hess OM,Meier B,Windecker S

更新日期：2005-06-01 00:00:00