Abstract:
:In the pharmaceutical industry, some tests for quality assurance before, during and after the manufacture of a drug product involve a two-stage sampling technique. We propose statistical testing procedures in a two-stage sampling problem with large within-class sample sizes. We also derive a two-stage sampling plan by minimizing the expected squared volume (or the generalized variance) of the confidence region related to the test. We present two examples to illustrate the proposed methods.
journal_name
Stat Medjournal_title
Statistics in medicineauthors
Shao J,Chow SCdoi
10.1002/sim.4780122104subject
Has Abstractpub_date
1993-11-15 00:00:00pages
1999-2008issue
21eissn
0277-6715issn
1097-0258journal_volume
12pub_type
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pub_type: 临床试验,杂志文章,随机对照试验
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