Relation between blood lead and urinary biogenic amines in community-exposed men.

Abstract:

:The cross-sectional relation between levels of urinary biogenic amines (dopamine, epinephrine, norepinephrine, and serotonin) and levels of blood lead was examined in a study of 645 male participants from a longitudinal study of aging. This stable population of men had initially been recruited from communities in and around Boston, Massachusetts, and had not been selected with regard to lead exposure. Blood lead samples and 24-hour and 2-hour urine specimens were collected during regularly scheduled clinic visits. In multivariate linear regression step-forward models, 24-hour epinephrine excretion was significantly and positively associated with blood lead (beta = 0.101 microgram(microgram/dl)-1 blood lead, SE (standard error) (beta) = 0.045, p = 0.026). Twenty-four-hour norepinephrine excretion was positively associated with blood lead (beta = 0.023 microgram(microgram/dl)-1 blood lead, SE(beta) = 0.029, p = 0.425), and both 24-hour dopamine (beta = -4.35 microgram(microgram/dl)-1 blood lead, SE(beta) = 6.90, p = 0.529) and 2-hour serotonin (beta = -0.348 microgram(microgram/dl)-1 blood lead, SE(beta) = 0.277, p = 0.210) excretion were negatively associated with blood lead; however, these relations did not achieve statistical significance. An increase of 10 micrograms/dl in blood lead was associated with an increase in epinephrine excretion of 11 micrograms/24 hours. These results support the hypothesis that epinephrine metabolism is influenced by low levels of lead exposure.

journal_name

Am J Epidemiol

authors

Payton M,Hu H,Sparrow D,Young JB,Landsberg L,Weiss ST

doi

10.1093/oxfordjournals.aje.a116785

subject

Has Abstract

pub_date

1993-11-15 00:00:00

pages

815-25

issue

10

eissn

0002-9262

issn

1476-6256

journal_volume

138

pub_type

杂志文章
  • The association between physical activity and subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis.

    abstract::Prior reports regarding the association between physical activity and subclinical cardiovascular disease have not been consistent. The authors assessed physical activity and walking pace via questionnaire among 6,482 US adults aged 45-84 years without prior clinical cardiovascular disease participating in the Multi-Et...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwn350

    authors: Bertoni AG,Whitt-Glover MC,Chung H,Le KY,Barr RG,Mahesh M,Jenny NS,Burke GL,Jacobs DR

    更新日期:2009-02-15 00:00:00

  • Prospective study of serum 25-hydroxyvitamin D concentration and mortality in a Chinese population.

    abstract::Prospective epidemiologic data on the association between vitamin D and mortality are limited, particularly in Asian populations. Among subjects in Linxian, China, the authors aimed to test whether baseline serum 25-hydroxyvitamin D (25(OH)D) concentrations in a prospective cohort were associated with all-cause mortal...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/aje/kws285

    authors: Lin SW,Chen W,Fan JH,Dawsey SM,Taylor PR,Qiao YL,Abnet CC

    更新日期:2012-12-01 00:00:00

  • Changing patterns of anal cancer incidence in the United States, 1940-1989.

    abstract::Anal cancer has been hypothesized to be associated with a sexually transmitted agent and, more recently, with the epidemic of human immunodeficiency virus (HIV). The authors used a descriptive incidence study to evaluate these hypotheses based on US data from the Surveillance, Epidemiology, and End Results (SEER) prog...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a117073

    authors: Melbye M,Rabkin C,Frisch M,Biggar RJ

    更新日期:1994-04-15 00:00:00

  • Vitamin supplement use and diabetes mellitus incidence among adults in the United States.

    abstract::In some studies, use of vitamin supplements has been inversely associated with the risk of several chronic diseases, but little is known about whether vitamin use affects the risk of diabetes mellitus. Using data from the National Health and Nutrition Examination Survey I Epidemiologic Follow-up Study, the author exam...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/153.9.892

    authors: Ford ES

    更新日期:2001-05-01 00:00:00

  • Familial aggregation of blood pressure in a rural Chinese community.

    abstract::This study investigated blood pressure in 1,183 Chinese nuclear families (mother, father, and first two children) via a cross-sectional 1994-1997 survey. The mother's, the father's, and the first sibling's blood pressures were each significantly and independently related to the second sibling's blood pressure after ad...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a009828

    authors: Wang X,Wang B,Chen C,Yang J,Fang Z,Zuckerman B,Xu X

    更新日期:1999-03-01 00:00:00

  • Abdominal obesity and age-related macular degeneration.

    abstract::Evidence for an association between age-related macular degeneration (AMD) and obesity is inconsistent. The authors examined associations between adiposity and AMD prevalence using 21,287 participants from the Melbourne Collaborative Cohort Study aged 40-69 years at baseline (1990-1994). For men, each increase of 0.1 ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwr005

    authors: Adams MK,Simpson JA,Aung KZ,Makeyeva GA,Giles GG,English DR,Hopper J,Guymer RH,Baird PN,Robman LD

    更新日期:2011-06-01 00:00:00

  • Recent exposure to particulate matter and C-reactive protein concentration in the multi-ethnic study of atherosclerosis.

    abstract::Ambient levels of particulate matter have been linked to cardiovascular disease. The mechanisms mediating these associations are poorly understood. One candidate mechanism is inflammation. Using data from the Multi-Ethnic Study of Atherosclerosis (2000-2002), the authors investigated the relation between exposure to p...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwj186

    authors: Diez Roux AV,Auchincloss AH,Astor B,Barr RG,Cushman M,Dvonch T,Jacobs DR Jr,Kaufman J,Lin X,Samson P

    更新日期:2006-09-01 00:00:00

  • A Population-Based Matched-Sibling Analysis Estimating the Associations Between First Interpregnancy Interval and Birth Outcomes.

    abstract::The association between a single interpregnancy interval (IPI) and birth outcomes has not yet been explored using matched methods. We modeled the odds of preterm birth, being small for gestational age, and having low birth weight in a second, live-born infant in a cohort of 192,041 sibling pairs born in Western Austra...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwy188

    authors: Regan AK,Ball SJ,Warren JL,Malacova E,Padula A,Marston C,Nassar N,Stanley F,Leonard H,de Klerk N,Pereira G

    更新日期:2019-01-01 00:00:00

  • Assessing nutrient intake with an abbreviated dietary interview.

    abstract::There is considerable interest in developing a means of assessing dietary intake of specific nutrients with minimal time and expense in epidemiologic studies. Using data from 1,682 individuals who were interviewed using an extensive food frequency dietary history, the authors examined the question of how many foods mi...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a114085

    authors: Byers T,Marshall J,Fiedler R,Zielezny M,Graham S

    更新日期:1985-07-01 00:00:00

  • Differences in birth weight and blood pressure at age 7 years among twins.

    abstract::Blood pressure later in life has been inversely associated with birth weight. However, concerns have been raised about whether this association merely reflects common environmental risk factors for both fetal growth restriction and high blood pressure or whether there is a genetic tendency to give birth to small babie...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/153.8.779

    authors: Zhang J,Brenner RA,Klebanoff MA

    更新日期:2001-04-15 00:00:00

  • Vitamin C deficiency in a population of young Canadian adults.

    abstract::A cross-sectional study of the 979 nonsmoking women and men aged 20-29 years who participated in the Toronto Nutrigenomics and Health Study from 2004 to 2008 was conducted to determine the prevalence of serum ascorbic acid (vitamin C) deficiency and its association with markers of chronic disease in a population of yo...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwp156

    authors: Cahill L,Corey PN,El-Sohemy A

    更新日期:2009-08-15 00:00:00

  • Determinants of plasma levels of beta-carotene and retinol. Skin Cancer Prevention Study Group.

    abstract::The associations of retinol and beta-carotene plasma concentrations with eight personal variables and the use of seven classes of cardiovascular drugs were studied in over 1,750 patients with nonmelanoma skin cancer enrolled at four American study centers in a cancer prevention clinical trial. Dietary carotene and fem...

    journal_title:American journal of epidemiology

    pub_type: 临床试验,杂志文章

    doi:10.1093/oxfordjournals.aje.a115365

    authors: Nierenberg DW,Stukel TA,Baron JA,Dain BJ,Greenberg ER

    更新日期:1989-09-01 00:00:00

  • Invited Commentary: Making Causal Inference More Social and (Social) Epidemiology More Causal.

    abstract::A society's social structure and the interactions of its members determine when key drivers of health occur, for how long they last, and how they operate. Yet, it has been unclear whether causal inference methods can help us find meaningful interventions on these fundamental social drivers of health. Galea and Hernán ...

    journal_title:American journal of epidemiology

    pub_type: 评论,杂志文章

    doi:10.1093/aje/kwz199

    authors: Jackson JW,Arah OA

    更新日期:2020-03-02 00:00:00

  • Connective tissue disease in southeastern Georgia: a case-control study of etiologic factors.

    abstract::The authors conducted a population-based case-control study of connective tissue disease in a four-county area in southeastern Georgia. Interviews with 44 cases and 88 controls were conducted in September and October of 1986. The association with a family history of these disorders was reconfirmed, and a positive asso...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a115348

    authors: Freni-Titulaer LW,Kelley DB,Grow AG,McKinley TW,Arnett FC,Hochberg MC

    更新日期:1989-08-01 00:00:00

  • Tracking strategies involving fourteen sources for locating a transient study sample: parents of sudden infant death syndrome infants and control infants.

    abstract::Strategies involving 14 sources were used to locate 230 parents of sudden infant death syndrome infants who died in Southern California between 1989 and 1992 and 255 parents of healthy, living infants matched by birth hospital, birth date, race and sex. The sample consisted of adults of reproductive age residing in So...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a008859

    authors: Klonoff-Cohen H

    更新日期:1996-07-01 00:00:00

  • Racial and Ethnic Disparities in the Incidence of Esophageal Cancer in the United States, 1992-2013.

    abstract::Racial and ethnic disparities in the incidence of esophageal cancer have not been thoroughly characterized with quantitative health-disparity measures. Using data from 1992-2013 from 13 US cancer registries in the Surveillance, Epidemiology, and End Results database, we assessed such disparities according to histologi...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwx221

    authors: Xie SH,Rabbani S,Petrick JL,Cook MB,Lagergren J

    更新日期:2017-12-15 00:00:00

  • Repeated measurements of vegetables, fruits, beta-carotene, and vitamins C and E in relation to lung cancer. The Zutphen Study.

    abstract::The authors studied the intake of vegetables, fruits, beta-carotene, and vitamins C and E in relation to the incidence of lung cancer. For 561 men from the town of Zutphen, the Netherlands, dietary history information was obtained in 1960, 1965, and 1970. During 1971-1990, 54 new cases of lung cancer were identified. ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a009113

    authors: Ocké MC,Bueno-de-Mesquita HB,Feskens EJ,van Staveren WA,Kromhout D

    更新日期:1997-02-15 00:00:00

  • The serum pepsinogen test as a predictor of gastric cancer: the Hisayama study.

    abstract::The authors examined whether a serum pepsinogen test (SPT) based on the combination of the serum pepsinogen I level and pepsinogen I/II ratio is a good predictor of gastric cancer occurrence in a general Japanese population. A total of 2,446 subjects aged > or =40 years were classified into negative, positive, and str...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwj088

    authors: Oishi Y,Kiyohara Y,Kubo M,Tanaka K,Tanizaki Y,Ninomiya T,Doi Y,Shikata K,Yonemoto K,Shirota T,Matsumoto T,Iida M

    更新日期:2006-04-01 00:00:00

  • Pesticides and lung cancer risk in the agricultural health study cohort.

    abstract::The authors examined the relation between 50 widely used agricultural pesticides and lung cancer incidence in the Agricultural Health Study, a prospective cohort study of 57,284 pesticide applicators and 32,333 spouses of farmer applicators with no prior history of lung cancer. Self-administered questionnaires were co...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwh290

    authors: Alavanja MC,Dosemeci M,Samanic C,Lubin J,Lynch CF,Knott C,Barker J,Hoppin JA,Sandler DP,Coble J,Thomas K,Blair A

    更新日期:2004-11-01 00:00:00

  • Smoking, alcohol consumption, and the risk of amyotrophic lateral sclerosis: a population-based study.

    abstract::Smoking has been posited as a possible risk factor for amyotrophic lateral sclerosis (ALS), but large population-based studies of patients with incident disease are still needed. The authors performed a population-based case-control study in the Netherlands between 2006 and 2009, including 494 patients with incident A...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kws015

    authors: de Jong SW,Huisman MH,Sutedja NA,van der Kooi AJ,de Visser M,Schelhaas HJ,Fischer K,Veldink JH,van den Berg LH

    更新日期:2012-08-01 00:00:00

  • The descriptive epidemiology of pneumococcal meningitis in New York City.

    abstract::A total of 348 cases of meningitis caused by Streptococcus pneumoniae were reported to and investigated by the New York City Department of Health during the six years 1973-1978. The descriptive epidemiology and completeness of reporting of this disease entity are presented. The total crude incidence was estimated at 1...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a113566

    authors: Henneberger PK,Galaid EI,Marr JS

    更新日期:1983-04-01 00:00:00

  • Angiogenic factors in maternal circulation and the risk of severe fetal growth restriction.

    abstract::Maternal angiogenic factors (placental growth factor, soluble fms-like tyrosine kinase 1 (Flt-1), and soluble endoglin) may be associated with fetal growth restriction, and the associations may differ according to stage of pregnancy. Among children born to pregnant women without preeclampsia in Norway between 1992 and...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwq373

    authors: Åsvold BO,Vatten LJ,Romundstad PR,Jenum PA,Karumanchi SA,Eskild A

    更新日期:2011-03-15 00:00:00

  • Sexual risk behavior and risk factors for HIV-1 seroconversion in homosexual men participating in the Tricontinental Seroconverter Study, 1982-1994.

    abstract::Trends in sexual behavior associated with incident infection with human immunodeficiency virus (HIV) type 1 are described and a case-control study was conducted to examine risk factors for HIV seroconversion in homosexual men who became infected with HIV between 1982 and 1994 from four geographic sites: Amsterdam, the...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a009311

    authors: Page-Shafer K,Veugelers PJ,Moss AR,Strathdee S,Kaldor JM,van Griensven GJ

    更新日期:1997-10-01 00:00:00

  • Total cholesterol and high density lipoprotein cholesterol as important predictors of erectile dysfunction.

    abstract::Although erectile dysfunction is frequently seen in patients with manifestations of arteriosclerotic disease, the independent contribution of serum cholesterol in predicting erectile dysfunction is unclear. The aim of this study was to examine the relation between serum cholesterol and erectile dysfunction. Medical hi...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a117181

    authors: Wei M,Macera CA,Davis DR,Hornung CA,Nankin HR,Blair SN

    更新日期:1994-11-15 00:00:00

  • Ewing's bone sarcoma, paternal occupational exposure, and other factors.

    abstract::To determine risk factors for Ewing's bone sarcoma, the authors interviewed mothers of 43 patients diagnosed between January 1978 and August 1986 and 193 controls in the San Francisco Bay Area, California, regarding medical and occupational history of parents and other factors related to the subjects and their immedia...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a116265

    authors: Holly EA,Aston DA,Ahn DK,Kristiansen JJ

    更新日期:1992-01-15 00:00:00

  • A validation of two motion sensors in the prediction of child and adult physical activity levels.

    abstract::The authors sought to assess the reliability and validity of two motion activity sensors in the prediction of observed physical activity levels in adults and children by means of two studies at North Dakota State University in Fargo, North Dakota. In study 1, 50 adults were observed in fall 1984 for one hour of recrea...

    journal_title:American journal of epidemiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/oxfordjournals.aje.a114121

    authors: Klesges RC,Klesges LM,Swenson AM,Pheley AM

    更新日期:1985-09-01 00:00:00

  • Alcohol-containing mouthwashes and oropharyngeal cancer: a spurious association due to underascertainment of confounders?

    abstract::Recently it has been suggested that the use of alcohol-containing mouthwashes may increase the risk of oropharyngeal cancer. Heavy alcohol intake and tobacco use are established causes of oropharyngeal cancer. Their use is associated with mouthwash use. In addition, alcohol and tobacco use both tend to be underreporte...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,评审

    doi:10.1093/oxfordjournals.aje.a008886

    authors: Shapiro S,Castellana JV,Sprafka JM

    更新日期:1996-12-15 00:00:00

  • Short-term temporal cycles in the frequency of suicide. United States, 1972-1978.

    abstract::Vital statistics data for the United States for the years 1972-1978 have been analyzed for variation in frequency of suicide by month, day of the week, day of the month, and phase of the lunar cycle. Frequency of suicide showed a peak in the spring months, a lesser peak in the fall and was lowest in December. Suicide ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a113608

    authors: MacMahon K

    更新日期:1983-06-01 00:00:00

  • Problems with the assessment of dietary fat in prostate cancer studies.

    abstract::The authors conducted a detailed review of studies on the association between prostate cancer and total dietary fat along with specific fatty acids. Overall, the 29 studies reporting actual dietary fat levels in grams of fat were heterogeneous, suggesting that pooling of the relative risks may be inappropriate. Hetero...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1093/aje/kwh243

    authors: Dennis LK,Snetselaar LG,Smith BJ,Stewart RE,Robbins ME

    更新日期:2004-09-01 00:00:00

  • Natural history of bone loss over 6 years among premenopausal and early postmenopausal women.

    abstract::The aims of this prospective cohort study were to determine rates of premenopausal and early postmenopausal bone loss, age at onset of bone loss, and whether rates of bone loss depend on baseline bone mineral density (BMD). The cohort of 614 women aged 24-44 years at baseline from the longitudinal Michigan Bone Health...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwf049

    authors: Bainbridge KE,Sowers MF,Crutchfield M,Lin X,Jannausch M,Harlow SD

    更新日期:2002-09-01 00:00:00