Invasive mycotic infections caused by Chaetomium perlucidum, a new agent of cerebral phaeohyphomycosis.

Abstract:

:We report the first two cases of invasive human mycoses caused by the phaeoid ascomycete, Chaetomium perlucidum, and review the English literature regarding invasive Chaetomium infections. Fatal disseminated disease involving the brain, heart, lungs, and spleen is described in an acute myelogenous leukemia patient. A second patient with a history of asthma and chronic bronchiectasis experiencing right-middle-lobe syndrome grew C. perlucidum from lung tissue. This study adds C. perlucidum to the list of other known neurotropic Chaetomium species, C. atrobrunneum and C. strumarium, and also documents this organism's ability to disseminate beyond the central nervous system.

journal_name

J Clin Microbiol

authors

Barron MA,Sutton DA,Veve R,Guarro J,Rinaldi M,Thompson E,Cagnoni PJ,Moultney K,Madinger NE

doi

10.1128/jcm.41.11.5302-5307.2003

subject

Has Abstract

pub_date

2003-11-01 00:00:00

pages

5302-7

issue

11

eissn

0095-1137

issn

1098-660X

journal_volume

41

pub_type

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