Abstract：
:The primary goal of engineering cartilage as a therapeutic approach is to restore the physiological conditions of an affected or defective tissue in the body. Cartilage tissue is distributed widely in the human body and possesses an organization related to the specific demand of a particular anatomical region. In selecting the proper material for engineering cartilage, the functional demands of the replacement tissue must be considered. In summary, there is a multitude of scaffolds, naturally occurring and synthetic, that are suitable for engineering cartilage. Investigators have shown that the characteristics of the neocartilage differ significantly depending upon which scaffold is used. There are also large differences when a single scaffold is tested in vitro as opposed to in vivo. Moreover, the addition of other materials internally or externally to the cartilage composite influences the physical and biomechanical properties of the newly formed tissue. The results achieved so far are extremely encouraging and motivate further investigative efforts in the field. The biochemical composition and, more importantly, the biomechanical properties of the native tissue still represent the ideal replacement tissue.
journal_name
Clin Plast Surgjournal_title
Clinics in plastic surgeryauthors
Randolph MA,Anseth K,Yaremchuk MJdoi
10.1016/s0094-1298(03)00070-1subject
Has Abstractpub_date
2003-10-01 00:00:00pages
519-37issue
4eissn
0094-1298issn
1558-0504pii
S0094-1298(03)00070-1journal_volume
30pub_type
杂志文章,评审abstract：:This article explores issues related to tissue engineering and composite tissue allografts that employ physiologic and anatomic autogenous replicates to restore tissue loss. Composite tissue allotransplantation has become a controversial option for reconstruction, most prominently for reconstruction involving the hand...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2006.12.004
更新日期：2007-04-01 00:00:00
abstract：:Wetting solutions play a crucial role in traditional lipoplasty by reducing blood loss in the aspirate and diminishing postoperative ecchymosis and edema. From the inception of ultrasound-assisted lipoplasty a "wet environment" has been considered essential for efficient fat emulsification and for control of thermal s...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：
更新日期：1999-04-01 00:00:00
abstract：:Human bites of the lips are very common. If less than 10 mm in size, they are treated conservatively and if greater, are treated surgically. Many lip bites are treated immediately, when infection is present, surgery is performed a few days later. ...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章
doi：
更新日期：1984-10-01 00:00:00
abstract：:Radiofrequency (RF)-based devices are used to improve face and neck laxity, a major feature of aging that until recently could only be addressed with surgery. Although these treatments are not meant to replace surgical procedures, patient satisfaction studies have been consistently high. For physicians offering these ...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2016.03.014
更新日期：2016-07-01 00:00:00
abstract：:Although any peripheral nerve may be compressed anywhere along its course, nerve compression syndromes typically occur at predictable sites with predictable clinical presentations. A detailed history and physical examination can establish a diagnosis, and electrodiagnostic studies and at times imaging can confirm it. ...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/s0094-1298(02)00103-7
更新日期：2003-04-01 00:00:00
abstract：:Traumatic nerve injuries are common conditions treated by hand surgeons, and the optimal treatment of a severed nerve requires providing a healthy wound bed, generous trimming to healthy nerve substance, and a minimal-tension approximation. The gold standard for repair of a critical nerve gap has been the nerve autogr...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2014.03.006
更新日期：2014-07-01 00:00:00
abstract：:This article covers many issues of particular interest to the care of the child who presents to the emergency department with a traumatic wound. General concepts regarding the staffing of an emergency department, staff qualifications, and their consultation patterns are reviewed. Issues pertaining to the management of...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：
更新日期：1998-10-01 00:00:00
abstract：:"Adipose tissue is a valuable, exploitable, appealing source of regenerative cells that can be used for a variety of clinical challenges. This article reviews the history of the development of adipose-derived cell science, particularly in the context of tissue engineering and regenerative medicine. It describes some o...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2014.12.010
更新日期：2015-04-01 00:00:00
abstract：:This article reviews 5 areas in burn care that increasingly use evidence-based medicine to optimize quality and safety: resuscitation protocols, transfusion practices, vascular access, venous thromboembolic prophylaxis, and rational use of antibiotics. ...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2017.02.015
更新日期：2017-07-01 00:00:00
abstract：:I believe that if one follows the precautions outlined, including a time-tested surgical technique and thorough clinical history and physical examination, the operation of blepharoplasty should prove to be one of the most gratifying aesthetic operations. ...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：:Surface aesthetics of an attractive nose result from certain lines, shadows, and highlights with specific proportions and breakpoints. Analysis emphasizes geometric polygons as aesthetic subunits. Evaluation of the complete nasal surface aesthetics is achieved using geometric polygons to define the existing deformity ...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2015.09.004
更新日期：2016-01-01 00:00:00
abstract：:In summary, the commonest late physical complications of the burn injury have been reviewed and an approach to their management described. An understanding of the pathophysiology of the conditions is invaluable in planning one's approach to these problems. The techniques to control and correct chronic wound and hypert...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章
doi：
更新日期：1977-10-01 00:00:00
abstract：:This study used stromal vascular fraction gel (SVF-gel), a mechanically processed fat-derived product, to treat eye bag and tear trough deformity. SVF-gel is prepared by a process of centrifugation and intersyringe shifting and is particularly rich in SVF cells and native adipose extracellular matrix. SVF-gel injectio...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2019.09.001
更新日期：2020-01-01 00:00:00
abstract：:Growth factors exert a powerful influence over wound healing. They control the growth, differentiation, and metabolism of cells. Although their influence on wound repair has been studied, there are only a few reports in which growth factors applied topically exerted a positive influence on wound repair. However, there...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：
更新日期：1998-07-01 00:00:00
abstract：:Remarkable advances in burn care have been made over recent decades, and it is recognized that the organized efforts of burn teams are required to continue enhancing survival rates and quality of life for patients. Patients with major burns are unique, representing one of the most severe models of trauma, and therefor...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2009.05.015
更新日期：2009-10-01 00:00:00
abstract：:The main goals of treating severe crush injuries are debriding away devitalized tissue and filling any resultant dead space with vascularized tissue. In the authors' experience, the most ideal methods for soft tissue coverage in treating crush injuries are the iliac flap, the adipofascial lateral arm flap, and the gra...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2016.11.002
更新日期：2017-04-01 00:00:00
abstract：:There are three mechanisms of bone formation that underlie the use of the different types of implants. In osteogenesis, viable osteoblasts and preosteoblasts are transplanted from one part of the body to the site where new bone is needed; cancellous marrow grafts are an example of such osteogenic engraftment. In osteo...
journal_title：Clinics in plastic surgery
pub_type： 历史文章,杂志文章,评审
doi：
更新日期：1985-04-01 00:00:00
abstract：:Great progress has been made in both the basic science and the clinical knowledge base used in orbital reconstruction. With this, increasing complex orbital reconstructive problems are better managed. The diagnosis, treatment plan, and the actual reconstruction have evolved to a higher level. Several areas of progress...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：
更新日期：1992-01-01 00:00:00
abstract：:Upper extremity reconstruction may be greatly facilitated by "thinking nerve" in the initial evaluation. Frequently, the obvious soft tissue deformity or bone or joint pathology distracts the reconstructive surgeon from an underlying nerve problem. When pain is a portion of the presenting complaints, thinking nerve be...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：
更新日期：1989-07-01 00:00:00
abstract：:The most common precancerous skin lesions are actinic keratoses, Bowen's disease, and keratoacanthoma. Actinic keratoses appear over the exposed areas of the body as the result of actinic radiation. Bowen's disease is most probably secondary to the effects of internal carcinogens. Keratoacanthomas are self-limited les...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章
doi：
更新日期：1980-07-01 00:00:00
abstract：:This article presents a survey of some of the nonpigmented cutaneous lesions that have the propensity or possibility to progress or transform into malignancies. For each lesion, the author discusses clinical appearance and course, histologic features, and general recommendations for treatment. ...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：
更新日期：1987-04-01 00:00:00
abstract：:The "marriage" or union of aggressive truncal liposuction with modified abdominoplasty techniques has been applied by the authors to treat patients with abdominal deformities marked by lower abdominal skin excess, abdominal muscle laxity, and excess adipose tissue on the abdominal wall and in adjacent contours. In the...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2004.03.014
更新日期：2004-10-01 00:00:00
abstract：:Many large-diameter myelinated axons in spinal dorsal roots contain carbonic anhydrase activity, whereas few small-diameter ventral root axons stain for this enzyme. This differential localization of carbonic anhydrase in sensory and motor nerve fibers is indicative of the potential of carbonic anhydrase histochemistr...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章
doi：
更新日期：1985-04-01 00:00:00
abstract：:Low-level laser-assisted liposuction (LLLL), known as the Neira 4 L technique, is an excellent adjuvant tool for the surgeon practicing liposculpture. A low-level laser is used to create a transitory pore in the cell membrane of the adipocyte to move fat from inside the cell to the interstitial space outside without k...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章
doi：10.1016/j.cps.2005.09.005
更新日期：2006-01-01 00:00:00
abstract：:Ambulatory surgery in a private plastic surgery office is a practical and desirable reality. This can be achieved only in a properly staffed facility. A small number of employees are needed but each must be carefully selected for proper qualifications and attributes, appropriate training and skills necessary to execut...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章
doi：
更新日期：1983-04-01 00:00:00
abstract：:Fibroproliferative disorders (FPDs) are common and serious disorders. Hypertrophic scar (HSc) and keloids represent the dermal equivalents of FPD and impose lower mortality but great morbidity. This article reviews current knowledge in the pathophysiology and molecular and cellular characteristics of postburn HSc. Add...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：10.1016/j.cps.2009.05.014
更新日期：2009-10-01 00:00:00
abstract：:The Pittsburgh Tissue Engineering Initiative (PTEI) is the prime catalyst for tissue-engineering research and the development of a viable for-profit tissue-engineering industry in southwestern Pennsylvania. PTEI operates targeted programs that support commercializable research; provide professional and community educa...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章
doi：
更新日期：1999-10-01 00:00:00
abstract：:Microsurgical free tissue transfer allows for the immediate reconstruction of any composite mandibular defect. Most patients are candidates for reconstruction, and careful preoperative planning is an important key to success. Osteocutaneous free tissue transfer is currently the reconstructive modality of choice. The t...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章,评审
doi：
更新日期：1995-01-01 00:00:00
abstract：:This article describes the surgical procedures used for the aesthetic improvements of the flanks and abdomen. A clinical classification for patient selection regarding when to use liposuction, surgery, or both, is included. Isolated flankplasty, isolated abdominoplasty, and combined flanks with abdominoplasty performe...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：:We are in a state of evolution in long-term hair removal. Safe and effective technology is now available. Lasers will always become smaller, faster, and perhaps more effective. For those interested in offering this procedure, evidence indicates that we are beyond the experimental phase. The treating physician should c...
journal_title：Clinics in plastic surgery
pub_type： 杂志文章
doi：
更新日期：2000-04-01 00:00:00
