Clinical applications of autografts, conduits, and allografts in repair of nerve defects in the hand: current guidelines.

Abstract:

:Traumatic nerve injuries are common conditions treated by hand surgeons, and the optimal treatment of a severed nerve requires providing a healthy wound bed, generous trimming to healthy nerve substance, and a minimal-tension approximation. The gold standard for repair of a critical nerve gap has been the nerve autograft. However, results are generally less favorable than direct suture. Autogenous and synthetic conduits and processed nerve allografts have been developed as less morbid and more convenient alternatives to autografts, but the reported outcomes have been uneven. Engineered neural tissues show great promise in inducing nerve regeneration across a gap.

journal_name

Clin Plast Surg

authors

Rinker B,Vyas KS

doi

10.1016/j.cps.2014.03.006

subject

Has Abstract

pub_date

2014-07-01 00:00:00

pages

533-50

issue

3

eissn

0094-1298

issn

1558-0504

pii

S0094-1298(14)00037-6

journal_volume

41

pub_type

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