Abstract：
:Fatigue is the most commonly reported, most debilitating, and most poorly understood Post-Polio Sequelae (PPS). Postmortem studies of 50 years ago documented frequent and severe poliovirus-induced lesions within the Reticular Activating System (RAS). Recently, neuropsychological testing has documented marked attention deficits in polio survivors reporting severe fatigue. However, neither of these findings has yet been related to the pathophysiology of post-polio fatigue. Magnetic resonance imaging of the brain was performed in 22 polio survivors carefully screened to eliminate the effect of comorbidities. Subjects rated the severity of their daily fatigue and subjective problems with attention, cognition, and memory. Small discrete or multiple punctate areas of hyperintense signal (HS) in the reticular formation, putamen, medial leminiscus, or white matter tracts were imaged in 55% of the subjects reporting high fatigue and in none of those reporting low fatigue. The presence of HS significantly correlated with fatigue severity and subjective problems in attention, concentration, staying awake, recent memory, and thinking clearly. The lack of significant correlations between HS or fatigue severity and age, severity of the acute polio, depressive symptoms, or difficulty sleeping militates against these factors as either causing HS or producing fatigue. These preliminary findings suggest that poliovirus-induced lesions in the Brain Activating System may underlie the subjective fatigue and attention deficits reported by polio survivors.
journal_name
Arch Phys Med Rehabiljournal_title
Archives of physical medicine and rehabilitationauthors
Bruno RL,Cohen JM,Galski T,Frick NMsubject
Has Abstractpub_date
1994-05-01 00:00:00pages
498-504issue
5eissn
0003-9993issn
1532-821Xjournal_volume
75pub_type
杂志文章abstract：OBJECTIVE:To determine the predictive value of discharge destination as a surrogate for defining unfavorable outcome at 3- and 12-months poststroke. DESIGN:Analysis of the prospectively collected data from a randomized, placebo-controlled trial in patients with ischemic stroke presenting within 3 hours of symptom onse...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2012.02.032
更新日期：2012-08-01 00:00:00
abstract：OBJECTIVE:To develop and evaluate the psychometric properties of an item set measuring economic quality of life (QOL) for use by individuals with disabilities. DESIGN:Survey. SETTING:Community settings. PARTICIPANTS:Individuals with disabilities completed individual interviews (n=64), participated in focus groups (n...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2014.02.030
更新日期：2015-04-01 00:00:00
abstract：:Spastic contractures are a common problem which frequently requires the use of splinting or casting. Customized adjustable orthoses can reduce contractures without the problems often associated with these procedures. These devices reduced contractures in a head-injured patient's severely spastic wrist and ankles. As a...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1985-06-01 00:00:00
abstract：OBJECTIVES:To conduct evidence-based review of cognitive rehabilitation intervention research conducted in persons with multiple sclerosis (MS), to classify level of evidence, and to generate recommendations for interventions in this area. DATA SOURCES:An open (no year limits set) search of Medline, PsychInfo, and CIN...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,评审
doi：10.1016/j.apmr.2007.10.019
更新日期：2008-04-01 00:00:00
abstract：:The purpose of this study was to evaluate and compare resistance exercise training with and without pelvic stabilization on the development of isolated lumbar extension strength. Isometric torque of the isolated lumbar extensor muscles was measured at seven positions through a 72 degree range-of-motion on 47 men and 3...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1994-02-01 00:00:00
abstract：OBJECTIVE:To determine if there was a change in the number of outpatient physical therapy (PT) and occupational therapy (OT) visits for Medicare beneficiaries, and in the number of beneficiaries receiving extended courses of >12 therapy visits, after the Jimmo vs Sebelius settlement. DESIGN:Cross-sectional analysis of...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2018.07.435
更新日期：2019-01-01 00:00:00
abstract：:The alien hand syndrome classically consists of involuntary movements accompanied by a feeling of foreignness and personification of the affected limb. Autocriticism, in which patients criticize and express astonished frustration with the behavior of the autonomous limb, is a commonly noted feature. Most cases of alie...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/s0003-9993(99)90114-4
更新日期：1999-02-01 00:00:00
abstract：OBJECTIVE:To show cortical reorganization in hemiparetic patients with a primary motor cortex (M1) infarct including the precentral knob by using functional magnetic resonance imaging (fMRI). DESIGN:Case-control. SETTING:Outpatient clinics in the rehabilitation department of a university hospital. PARTICIPANTS:Two s...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2004.11.043
更新日期：2005-08-01 00:00:00
abstract：OBJECTIVE:To examine the effect of pulmonary rehabilitation (PR) (exercise and education) or exercise training (ET) on exercise capacity, health-related quality of life (HRQOL), symptoms, frequency of exacerbations, and mortality compared with no treatment in adults with bronchiectasis. DATA SOURCES:Computer-based dat...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,评审
doi：10.1016/j.apmr.2016.05.017
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVE:To assess the efficacy of extracorporeal shockwave therapy (ESWT) and provide clinicians with an evidence base for their clinical decision making. DATA SOURCES:PubMed, MEDLINE, Embase, Cochrane Central Register of Controlled Trials, and Evidence-Based Medicine Reviews. STUDY SELECTION:All randomized or quas...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.apmr.2014.01.033
更新日期：2014-08-01 00:00:00
abstract：OBJECTIVE:To determine whether social skills deficits including unskilled, inappropriate behavior, problems reading social cues (social perception), and mood disturbances (such as depression and anxiety) could be remediated after severe traumatic brain injuries. DESIGN:Randomized controlled trial comparing a social sk...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.apmr.2008.02.029
更新日期：2008-09-01 00:00:00
abstract：:Twenty-seven normal, healthy women participated in this study, which investigated three methods of increasing the isometric strength of the quadriceps femoris through a six-week training program. Three experimental exercise groups were formed: A, eccentric, B, concentric, and C, isometric. The peak isometric torque of...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1985-03-01 00:00:00
abstract：:Results from five independent studies from our laboratory indicate that cathodal high-voltage pulsed current (HVPC) significantly curbs posttraumatic edema formation in several animal models. Conversely, anodal HVPC did not curb edema formation. The mechanism by which HVPC reduces edema formation is unknown. We hypoth...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/s0003-9993(95)80665-2
更新日期：1995-04-01 00:00:00
abstract：:A semi-flexible socket fitted to a series of 47 consecutive below-knee amputees is evaluated, and the problems in assessing prosthetic components and appropriate methodology are discussed. The results suggest that this type of socket deserves wider use and further evaluation in active amputees, where comfort, perspira...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1975-09-01 00:00:00
abstract：OBJECTIVE:To investigate whether the aerobic capacity of older adults who underwent a lower limb amputation is associated with the presence, cause (traumatic or vascular), and level of amputation (transtibial or transfemoral). DESIGN:Cross-sectional descriptive. SETTING:Human motion laboratory at a rehabilitation cen...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2012.05.020
更新日期：2012-11-01 00:00:00
abstract：:Unilateral brachial plexus injury is a rare complication of thoracoscopic sympathectomy, which is generally considered to be a simple and safe procedure. We report on a 26-year-old man who developed weakness and numbness of the right arm after thoracoscopic sympathectomy for hyperhidrosis. Electromyographic study reve...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/s0003-9993(03)00135-7
更新日期：2003-09-01 00:00:00
abstract：OBJECTIVE:To investigate how exercise training and detraining affect oxidized low-density lipoprotein (Ox-LDL)-potentiated platelet function in men. DESIGN:Cohort study. SETTING:Department of physical medicine and rehabilitation. PARTICIPANTS:Ten sedentary men (mean age +/- standard error of the mean, 21.6+/-0.2 y) ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2003.08.112
更新日期：2004-09-01 00:00:00
abstract：OBJECTIVE:To investigate the effects of long-term Tai Chi practice on balance control when healthy elderly Tai Chi practitioners stood under reduced or conflicting somatosensory, visual, and vestibular conditions, as compared with healthy elderly non-Tai Chi practitioners and young subjects. DESIGN:Cross-sectional stu...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2003.02.002
更新日期：2004-01-01 00:00:00
abstract：:The factors responsible for the increased susceptibility to decubitus ulcers of the insensitive skin of spinal cord injury (SCI) patients are not known. Autonomic dysfunction leading to defective vascularity is a possibility. SCI removes cerebral control of the isolated nervous system which may mimic denervation hyper...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/0003-9993(86)90073-0
更新日期：1986-03-01 00:00:00
abstract：OBJECTIVES:To operationalize research findings about a medical rehabilitation classification and payment model by building a prototype of a prospective payment system, and to determine whether this prototype model promotes payment equity. This latter objective is accomplished by identifying whether any facility or paym...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/s0003-9993(97)90299-9
更新日期：1997-12-01 00:00:00
abstract：:Disorders of attention are common after a variety of insults to the central nervous system. Clinically observable disorders of attention have complex relationships to the hypothesized underlying core deficits that were reviewed in a previous article. Thus, the process of evaluating such deficits is equally complex. Tr...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,评审
doi：
更新日期：1992-11-01 00:00:00
abstract：OBJECTIVES:To investigate the association between active knee flexion at initial (1-2 wk) and final (7 wk) outpatient visits after total knee arthroplasty (TKA), and to develop a guide for the expected progression of knee flexion in the subacute postoperative phase. DESIGN:Prospective case series. SETTING:Rehabilitat...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2014.02.015
更新日期：2014-06-01 00:00:00
abstract：OBJECTIVE:To explore the effects on motor function and impairment of mobilization and tactile stimulation for the paretic arm and hand after stroke. DESIGN:Replicated single-system series, ABA design. SETTING:The stroke rehabilitation ward of a community hospital in the United Kingdom. PARTICIPANTS:Consecutive sampl...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2008.03.016
更新日期：2008-10-01 00:00:00
abstract：OBJECTIVE:To evaluate the performance of a new walking aid, the WalkAbout, for severely disabled and elderly persons. DESIGN:Crossover design. SETTING:Laboratory and nursing home. PARTICIPANTS:Sixty-five patients who could not walk independently. INTERVENTIONS:The top rail of the WalkAbout completely encircles the ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2004.04.040
更新日期：2004-12-01 00:00:00
abstract：:The purpose of this study was to determine the reliability of isokinetic and isometric measurement of strength for tests of knee extension and hip abduction on men with mental retardation (MR). In addition, the relationships between isokinetic measures of peak torque (PT) and total work (TW) and isometric peak torque ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/0003-9993(93)90012-y
更新日期：1993-08-01 00:00:00
abstract：OBJECTIVE:To determine if patients' level of effort (LOE) in therapy sessions during traumatic brain injury (TBI) rehabilitation modifies the effect of compliance with the 3-Hour Rule of the Centers for Medicare & Medicaid Services. DESIGN:Propensity score methodology applied to the TBI Practice-Based Evidence databas...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2019.01.014
更新日期：2019-10-01 00:00:00
abstract：:A recently developed abdominal muscle test (AMT), using four levels of difficulty to assess abdominal muscle strength, was validated by examination of the functional interrelationship between the individual muscles during the AMT, and by determining the relationship between the AMT level of difficulty and electromyogr...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1994-09-01 00:00:00
abstract：OBJECTIVE:To study the value of physical, mental, and social characteristics as predictors of functional outcome of elderly amputees. DESIGN:Prospective, inception cohort study; comparisons with reference populations. SETTING:Main hospitals, rehabilitation centers, nursing homes, patients' own residence settings in 1...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/s0003-9993(02)04952-3
更新日期：2003-06-01 00:00:00
abstract：OBJECTIVE:To investigate the effects of a late-phase exercise program for patients who underwent total hip arthroplasty (THA) 4 to 12 months earlier. DESIGN:A single-blind, randomized controlled trial. SETTING:Exercises were performed in subjects' homes. Exercise instruction and measurements taken before and after th...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.apmr.2003.11.022
更新日期：2004-07-01 00:00:00
abstract：:Lumbosacral and associated leg pain and paresthesias arousing patients from a sound sleep, or Vesper's curse, has been previously reported. An increase in right atrial filling pressure reflected in elevated paraspinal venous volumes within the reduced confines of a stenotic lumbar spine has been cited as the cause of ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1990-05-01 00:00:00
