Abstract:
PURPOSE:To evaluate the intrapatient reproducibility of the extent and anatomic distribution of air trapping at sequential expiratory thin-section computed tomographic (CT) examinations in heart-lung transplant recipients. MATERIALS AND METHODS:Nineteen heart-lung transplant recipients (eight with and 11 without bronchiolitis obliterans syndrome [BOS]) underwent three expiratory CT examinations within 1 hour. Residual volumes were measured at CT. Anatomic distribution and extent of air trapping were scored by two observers at two independent readings, and the reproducibility of observations was calculated for each feature. CT examination results were compared by using an analysis of variance that took into account interobserver and BOS and non-BOS effects. The Spearman rank correlation coefficient was calculated to test the association between variability of residual volumes and variability of the extent of air trapping. RESULTS:Residual volumes did not significantly differ between the three CT examinations (P =.556). Reproducibility values for findings of anatomic distribution of air trapping ranged from 84% to 95%, with a tendency toward improved reproducibility in patients without BOS. Mean reproducibility values for the extent of air trapping ranged from 97.1% to 97.7%, and no substantial difference in these values between patients with and those without BOS was observed. The Spearman rank coefficient for the correlation between variability of residual volumes and variability of extent of air trapping ranged from 0.382 to 0.568 (P =.105-.016). No interobserver effect was detected (P =.944). CONCLUSION:Anatomic distribution and extent are reproducible characteristics of air trapping. No substantial variability of air trapping occurs in functionally stable heart-lung transplant recipients.
journal_name
Radiologyjournal_title
Radiologyauthors
Bankier AA,Van Muylem A,Scillia P,De Maertelaer V,Estenne M,Gevenois PAdoi
10.1148/radiol.2293020827subject
Has Abstractpub_date
2003-12-01 00:00:00pages
737-42issue
3eissn
0033-8419issn
1527-1315pii
229/3/737journal_volume
229pub_type
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