Abstract:
PURPOSE:To prospectively determine the accuracy of 64-section computed tomographic (CT) angiography for the depiction of coronary artery disease (CAD) that induces perfusion defects at myocardial perfusion imaging with single photon emission computed tomography (SPECT), by using myocardial perfusion imaging as the reference standard. MATERIALS AND METHODS:All patients gave written informed consent after the study details, including radiation exposure, were explained. The study protocol was approved by the local institutional review board. In patients referred for elective conventional coronary angiography, an additional 64-section CT angiography study and a myocardial perfusion imaging study (1-day adenosine stress-rest protocol) with technetium 99m-tetrofosmin SPECT were performed before conventional angiography. Coronary artery diameter narrowing of 50% or greater at CT angiography was defined as stenosis and was compared with the myocardial perfusion imaging findings. Quantitative coronary angiography served as a reference standard for CT angiography. RESULTS:A total of 1093 coronary segments in 310 coronary arteries in 78 patients (mean age, 65 years +/- 9 [standard deviation]; 35 women) were analyzed. CT angiography revealed stenoses in 137 segments (13%) corresponding to 91 arteries (29%) in 46 patients (59%). SPECT revealed 14 reversible, 13 fixed, and six partially reversible defects in 31 patients (40%). Sensitivity, specificity, and negative and positive predictive values, respectively, of CT angiography in the detection of reversible myocardial perfusion imaging defects were 95%, 53%, 94%, and 58% on a per-patient basis and 95%, 75%, 96%, and 72% on a per-artery basis. Agreement between CT and conventional angiography was very good (96% and kappa = 0.92 for patient-based analysis, 93% and kappa = 0.84 for vessel-based analysis). CONCLUSION:Sixty-four-section CT angiography can help rule out hemodynamically relevant CAD in patients with intermediate to high pretest likelihood, although an abnormal CT angiography study is a poor predictor of ischemia.
journal_name
Radiologyjournal_title
Radiologyauthors
Gaemperli O,Schepis T,Valenta I,Koepfli P,Husmann L,Scheffel H,Leschka S,Eberli FR,Luscher TF,Alkadhi H,Kaufmann PAdoi
10.1148/radiol.2482071307subject
Has Abstractpub_date
2008-08-01 00:00:00pages
414-23issue
2eissn
0033-8419issn
1527-1315pii
2482071307journal_volume
248pub_type
杂志文章相关文献
RADIOLOGY文献大全abstract::This case series describes the radiologic appearances of gynecomastoid hyperplasia of the breast in our experience. The clinical histories, breast images, and histopathologic findings in six women were reviewed. At mammography, there was no abnormality in two women, an enlarging asymmetric density in three women, and ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.214.2.r00fe24553
更新日期:2000-02-01 00:00:00
abstract:PURPOSE:To evaluate the sensitivity and specificity of biphasic computed tomography (CT) with mesenteric CT angiography in the diagnosis of acute mesenteric ischemia (AMI). MATERIALS AND METHODS:Sixty-two patients with clinically suspected AMI underwent prospective imaging with biphasic multi-detector row CT. Mesenter...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2291020991
更新日期:2003-10-01 00:00:00
abstract::A grid consisting of a focused array of radiopaque strips has been constructed. No interspace material is employed, and, during an exposure, the arrangement moves so that the grid strips remain focused and a uniform film density is obtained. Preliminary measurements and radiographs of patients indicate that such a dev...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.135.3.7384470
更新日期:1980-06-01 00:00:00
abstract:PURPOSE:To analyze the results of round 1 of the population-based Valencia Breast Cancer Screening Program. MATERIALS AND METHODS:In this program, 78,224 (72.98%) of the 107,178 women invited (aged 45-65 years) underwent screening. Complementary views were obtained in 5,771 women (7.38%). Among the total population st...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.206.1.9423680
更新日期:1998-01-01 00:00:00
abstract::Twenty-six patients with an eqivocal portal defect on conventional nuclear images were evaluated with a multiplane tomographic nuclear scanner and gray scale ultrasound. In most cases the correct determination (normal or abnormal) for an area of decreased uptake could be made from the multiplane tomographic scans. Whe...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/122.3.773
更新日期:1977-03-01 00:00:00
abstract::Scattered radiation and veiling glare in digital subtraction angiography degrade contrast signals in a nonlinear and nonuniform way. This effect prohibits direct use of image data for accurate iodine measurement or energy subtraction imaging. Two techniques based on the use of scanning lead bars were proposed to measu...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.157.1.3898220
更新日期:1985-10-01 00:00:00
abstract:PURPOSE:To assess the optimal timing for coronary magnetic resonance (MR) angiography in children with congenital heart disease by using dual cardiac phase whole-heart MR imaging. MATERIALS AND METHODS:The local institutional review board approved this study, and informed consent was obtained from parents or guardians...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.11101659
更新日期:2011-07-01 00:00:00
abstract:PURPOSE:To evaluate the usefulness of power Doppler ultrasonography (US) with a microbubble contrast agent in assessing the therapeutic response of hepatocellular carcinomas (HCCs) treated with percutaneous radio-frequency (RF) ablation. MATERIALS AND METHODS:Forty patients with 45 nodular HCC lesions 1.0-3.8 cm in di...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.217.2.r00oc07558
更新日期:2000-11-01 00:00:00
abstract::Eighteen cases of long-standing rheumatoid arthritis and superimposed pyarthrosis were reviewed to determine the most distinguishing radiographic features. Soft-tissue changes allowed earlier diagnosis in the knee and ankle joints and consisted of large asymmetrical joint effusion and fat-pad edema. Bony articular cha...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/122.1.17
更新日期:1977-01-01 00:00:00
abstract::In order to evaluate the efficacy of bedside chest radiography, a prospective study was completed of 140 patients admitted to the surgical and medical intensive care units over a two-month period. A total of 1132 consecutive bedside radiographs was analyzed for malposition of tubes and lines and interval changes in th...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.149.1.6611930
更新日期:1983-10-01 00:00:00
abstract::In induced bleeding experiments on dogs, 99mTc-sulfur colloid was a suitable agent for detecting the bleeding site in the small intestine, providing that the site was distant from the liver and spleen. Bleeding sites were detectable at rates as low as 0.1 ml/min. When induced in the sigmoid or descending colon, the si...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/124.3.753
更新日期:1977-09-01 00:00:00
abstract::A method is described for the rapid and easy manipulation of a Kimray-Greenfield vena cava filter beyond an obstructing eustachian valve. ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.150.1.6689770
更新日期:1984-01-01 00:00:00
abstract::The authors reviewed 76 magnetic resonance (MR) images of 38 patients with osteosarcoma treated with preoperative chemotherapy (intraarterial cisplatin with or without systemic chemotherapy). Histologic maps of the surgical tumor specimens in 33 cases were correlated with either late-chemotherapy or postchemotherapy M...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.174.2.2296660
更新日期:1990-02-01 00:00:00
abstract::Twenty-eight patients with intra-abdominal mesenchymal sarcomas were examined with gray scale ultrasonography. Masses were present in the mesentery, abdominal hollow viscera, liver, and retroperitoneal areas. Four different ultrasonic patterns were observed in the extra hepatic abdominal masses: (a) hyperechoic masses...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/128.1.193
更新日期:1978-07-01 00:00:00
abstract::The authors describe their experience with methyl tertiary butyl ether (MTBE) in a larger series of patients than previously reported in order to acquaint physicians with both its effectiveness for dissolution of common bile duct calculi and the limitations of its use. Ten patients with 13 biliary calculi underwent pe...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.166.3.3340760
更新日期:1988-03-01 00:00:00
abstract:PURPOSE:To establish an imaging approach to visualize the 100-microm-thick hippocampal neuron-generating dentate granule cell layer (DGCL) consistently within a clinically feasible magnetic resonance (MR) imaging duration and to assess its sensitivity by quantifying the likelihood that it will be detected in healthy yo...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.09090897
更新日期:2010-03-01 00:00:00
abstract:PURPOSE:To evaluate whether changes in magnetic resonance (MR) imaging heterogeneity may aid assessment for pathologic complete response (pCR) to neoadjuvant chemotherapy (NACT) in primary breast cancer and to compare pCR with standard Response Evaluation Criteria in Solid Tumors response. MATERIALS AND METHODS:Instit...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.14130569
更新日期:2014-07-01 00:00:00
abstract:PURPOSE:To examine geographic variation in providers' use of diagnostic imaging to identify potential targets for quality improvement initiatives after adjusting for imaging referral across hospital referral regions (HRRs). MATERIALS AND METHODS:Using two Centers for Medicare and Medicaid Services datasets, the author...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.15141964
更新日期:2015-06-01 00:00:00
abstract::The cases of 14 patients seen 6 weeks to 7 years after gunshot wounds with painful, restrictive joint disease and retained intra-articular bullets were reviewed. Twelve patients had radiographic findings characteristic of lead synovitis. The earliest finding was a fine, punctate deposition of radiopaque lead on the ar...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.156.2.4011890
更新日期:1985-08-01 00:00:00
abstract:PURPOSE:To differentiate prostate cancers of different histopathologic grades with dynamic gadolinium-enhanced magnetic resonance (MR) imaging. Results with a conventional small-molecular contrast medium (CM) were compared to those with a prototypic macromolecular CM. MATERIALS AND METHODS:High- and low-grade tumors, ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.213.1.r99oc43265
更新日期:1999-10-01 00:00:00
abstract::The effect of nuclear magnetic resonance (NMR) imaging on six representative cardiac pacemakers was studied. The results indicate that the threshold for initiating the asynchronous mode of a pacemaker is 17 gauss. Radiofrequency levels are present in an NMR unit and may confuse or possibly inhibit demand pacemakers, a...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.147.1.6828720
更新日期:1983-04-01 00:00:00
abstract:PURPOSE:To evaluate the portal and arterial blood supplies to dysplastic nodules in the cirrhotic liver with computed tomography (CT) during arterial portography (CTAP) and CT hepatic arteriography (CTHA). MATERIALS AND METHODS:Nineteen histopathologically proved low-grade dysplastic nodules and 13 high-grade dysplast...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.214.3.r00mr12869
更新日期:2000-03-01 00:00:00
abstract::Cortical fissuring, a well-recognized radiographic sign of osteomyelitis, represents spread of infection through the haversian system with osteoclastic bone resorption. In the proper clinical setting this finding may be recognized before there is other evidence of bone destruction or periosteal reaction. Three cases a...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.141.1.7027310
更新日期:1981-10-01 00:00:00
abstract:PURPOSE:To evaluate the feasibility of reconstructing single and multiple targets by using fluorescence-enhanced tomography of a breast tissue phantom. MATERIALS AND METHODS:Frequency-domain fluorescence measurements were performed in cup-shaped tissue phantoms of clinically relevant size (diameter, 10 cm) in which si...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2343031725
更新日期:2005-04-01 00:00:00
abstract:PURPOSE:To evaluate the measurement with ultrasonography (US) of the gallbladder ejection fraction after slow-infusion cholecystokinin stimulation in patients with biliary symptoms and in individuals without symptoms. MATERIALS AND METHODS:Gallbladder volumes were calculated in 60 healthy volunteers after a 30-minute ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.204.1.9205230
更新日期:1997-07-01 00:00:00
abstract:PURPOSE:To evaluate the safety and efficacy of biliary intervention performed by means of percutaneous transjejunal access. MATERIALS AND METHODS:In 28 patients with conventional antecolic Roux-en-Y choledochojejunostomy or hepaticojejunostomy loops, 41 attempts were made at direct percutaneous entry into the jejunal ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.195.1.7892460
更新日期:1995-04-01 00:00:00
abstract::Clinical, pathologic, and computed tomographic (CT) findings were reviewed in 400 patients with ethmoid sinus disease, including 272 who had undergone surgery. The postoperative appearance of ethmoid sinuses on CT scans is a highly neglected subject in radiologic literature. The unique ethmoid anatomy permits a variet...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.159.3.3704140
更新日期:1986-06-01 00:00:00
abstract::To determine the prevalence of "nonobstructive" (impairment of gas transfer) emphysema in a select population of smokers with dyspnea, a retrospective study of patients with emphysema evident at high-resolution computed tomography (HRCT) was undertaken. Four hundred seventy HRCT studies were reviewed. In 47 cases, cen...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.182.3.1535900
更新日期:1992-03-01 00:00:00
abstract::Hyperpolarized metabolic magnetic resonance (MR) imaging offers greatly enhanced sensitivity to multinuclear MR spectroscopy, opening up a new tool with which to noninvasively assess metabolic changes in the diseased heart. In this issue of Radiology, O h-Ici et al ( 1 ) have demonstrated this ability by exploring the...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2016152489
更新日期:2016-03-01 00:00:00
abstract:PURPOSE:To assess the effectiveness of and complications associated with metallic stent placement for treatment of benign diseases of the colon. MATERIALS AND METHODS:With radiologic guidance, the authors placed metallic stents in 10 patients with benign diseases of the colon: Nine stents were placed in the rectosigmo...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2233010866
更新日期:2002-06-01 00:00:00