Abstract：
:Differences have been found among blacks, whites, Asians, and Hispanics in various areas of skin structure and function. Among them is the stratum corneum lipid (ceramide) content, which is highest in Asians, then Hispanics, then whites, and lowest in blacks. Melanosomal packaging and percutaneous absorption rates for specific compounds also vary among the different races. Reports supporting the occurrence of difference in TEWL, tyrosinase levels, skin elasticity, and water absorption rates between blacks and whites, and reaction to skin irritation have been conflicting. No significant differences in corneocyte size, skin thickness, and skin biomechanics have been reported.
journal_name
Dermatol Clinjournal_title
Dermatologic clinicsauthors
Richards GM,Oresajo CO,Halder RMdoi
10.1016/s0733-8635(03)00081-0subject
Has Abstractpub_date
2003-10-01 00:00:00pages
595-600issue
4eissn
0733-8635issn
1558-0520pii
S0733-8635(03)00081-0journal_volume
21pub_type
杂志文章,评审abstract：:Rothmund-Thomson syndrome is a rare inherited disorder characterized by poikilodermatous skin changes that appear in infancy. The inheritance is autosomal recessive. Patients exhibit variable features including skeletal abnormalities, juvenile cataracts, and a higher-than-expected incidence of malignancy. This article...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1995-01-01 00:00:00
abstract：:The technical advances of the last century changed the understanding of the science of cutaneous physiology and pathology and the role of the dermatologist. The major challenges the international dermatologic community faces today are the lack of a common, logical, and accepted language within the specialty; long-acce...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2007.11.002
更新日期：2008-04-01 00:00:00
abstract：:Psoriasis vulgaris is a chronic inflammatory skin disease that results from the complex interplay between keratinocytes, dendritic cells, and T cells. Keratinocytes trigger innate and adaptive immune responses. Dermal myeloid dendritic cells regulate T cell activation and production of cytokines and chemokines that am...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2014.09.002
更新日期：2015-01-01 00:00:00
abstract：:Cutaneous B-cell lymphomas represent a heterogeneous group of entities which show variation in histology, immunophenotype, and in prognosis. In the current review the morphologic spectrum of cutaneous B-cell lymphomas comprising primary and secondary cutaneous B-cell lymphomas is discussed according to the REAL classi...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70109-1
更新日期：1999-07-01 00:00:00
abstract：:In this article, practical and clinical aspects of photoprotection are discussed with emphasis on topical sunscreens. Protection against the adverse effects of sunlight includes prevention of the following: sunburn in normal individuals; acute phototoxic and photoallergic reactions; chronic skin damage (dermatoheliosi...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：
更新日期：1986-04-01 00:00:00
abstract：:Nail pigmentation is defined by the presence of melanin in the nail plate. It most frequently has the appearance of a longitudinal pigmented band, called longitudinal mel-anonychia (LM). LM is an important aspect of ungual pathology because it can be the first sign of nail apparatus melanoma. The aim of this article i...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2006.03.012
更新日期：2006-07-01 00:00:00
abstract：:Vasculitis may be defined as damage to blood vessels induced by pathologic processes, resulting in compromise of function of the organ in which the blood vessels reside. A large number of syndromes and disease processes exist in which vasculitis plays a key role. Selected vasculitic syndromes of special interest to de...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1990-10-01 00:00:00
abstract：:Treating the underlying pathophysiology of the wound remains of utmost importance. Several new treatment modalities may soon be available as adjunctive treatments. The efficacy of some remains to be established in well-controlled clinical studies. ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70414-9
更新日期：1997-01-01 00:00:00
abstract：:With simple, inexpensive therapy, virtually all venous ulcers heal without the need for hospitalization, skin grafting, growth factors, hyperbaric oxygen, or debilitating bed rest. Although the future promises to yield a greater understanding about the nature of these wounds and ways to treat them, one can benefit the...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1993-10-01 00:00:00
abstract：:This article, rather than presenting an overview of all available antifungal agents, has provided an update on new information about older agents, as well as evolving information about new agents, including those currently undergoing clinical trials. Among the azoles, ketoconazole will continue to be used as a major a...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：:Tetracyclines are known to exhibit multiple significant anti-inflammatory actions. This article describes the mechanisms of this anti-inflammatory activity, such as inhibition of chemotaxis, granuloma formation, and protease. The article also discusses the effectiveness of tetracyclines in treating such diseases as ac...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2007.01.012
更新日期：2007-04-01 00:00:00
abstract：:Pediatric dermatologic disease that have specific therapies and/or specific prophylactic measures are reviewed. Herpes simplex virus and varicella-zoster virus infections, human papillomavirus infections, and molluscum contagiosum infections are discussed with special emphasis on recent advances of therapy and prophyl...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70251-5
更新日期：1998-07-01 00:00:00
abstract：:One may accomplish certain closures without tension or distortion using blunt liposuction cannula dissection with or without suction-assisted lipectomy. If closure cannot be accomplished with adequate undermining and an appropriate flap design, the surgeon may first aspirate fat to allow use of the focally expanded sk...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1990-07-01 00:00:00
abstract：:Acne vulgaris alters the normal skin physiology, impairing stratum corneum and transepidermal water loss. A male's normal skin physiologic state is different than a female's and may have implications when choosing treatment when the skin is altered in a disease state. Transepidermal water loss, pH, and sebum productio...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2015.11.007
更新日期：2016-04-01 00:00:00
abstract：:In order to be considered an ectodermal dysplasia, a disorder should meet the following criteria: it must be congenital; it must be diffuse (not localized) and must involve the epidermis as well as at least one of its appendages; and it must not be progressive. Included is a discussion of some well-documented, as well...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:The goal of photochemotherapy in psoriasis is to attempt to lower the number of exposures and the total cumulative doses while still maintaining good control of the disease. PUVA has been modified by using better psoralen preparations and more effective light sources, and it also has been combined with other treatment...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1995-10-01 00:00:00
abstract：:Native Americans have a rich and complex heritage and culture. Although the genetic pool has changed with increasing integration with other Americans with different ancestry, there are important conditions that are unique to Native Americans, the most prominent example being actinic prurigo. The scientific literature ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(03)00076-7
更新日期：2003-10-01 00:00:00
abstract：:Much progress has been made over the past 10 years with regard to development of a vaccine active against HPV. Successful protection has been achieved in animal models using species-specific papillomaviruses; however, HPV diversity may delay the development of successful HPV vaccines, especially those designed as ther...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：10.1016/s0733-8635(05)70056-5
更新日期：1998-10-01 00:00:00
abstract：:The sensitizing capacity of double-headed haptens containing the pyrocatechol and alpha-methylene-gamma-butyrolactone groups reveals that only the pyrocatechol end is recognized as a sensitizer. Prior sensitization to the double-headed hapten provides protection against (induces immune tolerance to) further sensitizat...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:"Nail clipping is a simple technique for diagnosis of several nail unit dermatoses. This article summarizes the practical approach, utility, and histologic findings of a nail clipping in evaluation of onychomycosis, nail unit psoriasis, onychomatricoma, subungual hematoma, melanonychia, and nail cosmetics, and the for...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2014.12.011
更新日期：2015-04-01 00:00:00
abstract：:Advances in laser technology now permit the physician to provide an effective form of treatment for a large variety of cutaneous disorders for which no previous therapy or only poor forms of therapy previously existed. Additional refinements in both laser instruments and treatment techniques are certain to have a prof...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：
更新日期：1987-04-01 00:00:00
abstract：:Cutaneous manifestations of thyroid disease are protean in nature and can be divided into specific lesions such as the thyroglossal duct cyst and cutaneous metastases from thyroid malignancy, nonspecific signs secondary to thyroid hormone imbalance, and associated dermatologic and systemic disorders. This review repre...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(02)00009-8
更新日期：2002-07-01 00:00:00
abstract：:Extramammary Paget disease is an intraepidermal adenocarcinoma, most often limited to the epidermis, with typical cases affecting genital skin. When limited to the epidermis, primary extramammary Paget disease is not life-threatening, but invasive disease may portend a poor prognosis. Surgical excision remains the mai...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2019.02.002
更新日期：2019-07-01 00:00:00
abstract：:Nail psoriasis, melanonychia striata, and onychomycosis are relatively common nail disorders that have generated much research into their pathophysiology and treatment. The authors hope this discussion of the recent therapeutic developments for treating these disorders will not only inform but will also inspire furthe...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70145-5
更新日期：2000-01-01 00:00:00
abstract：:This article discusses ways to recognize and manage lymphomas and pseudolymphomas associated with drug exposure. Over the last 30 years, the classification of pseudolymphomas and lymphomas has undergone significant change, especially following the application of sophisticated immunostaining and gene rearrangement anal...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2007.01.008
更新日期：2007-04-01 00:00:00
abstract：:Dermatologists helped to develop the specialty of liposuction surgery and contributed to many of the innovations and instrumentation in this field. Dermatologists were trained side by side with other cosmetic surgeons as the procedure was introduced into the United States. Dermatologists have been important in teachin...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：
更新日期：1990-07-01 00:00:00
abstract：:Patients with urogenital complaints are frequently encountered by family practitioners, gynecologists, and dermatologists. This review article provides practical information regarding normal anatomy and embryology of the vulva, followed by a summary of procedural techniques. The new classifications of vulvar inflammat...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2010.07.005
更新日期：2010-10-01 00:00:00
abstract：:The anatomic region influences the dermoscopic features of different lesions. In this article, the particular characteristics of the scalp, mucosal membranes, and lesions located on the milk line are explained. In histopathology, the benign melanocytic lesions in these locations are also named nevi of special sites, c...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2013.07.003
更新日期：2013-10-01 00:00:00
abstract：:In this article, vulvar anatomy and histology are reviewed, and nonneoplastic and neoplastic epithelial disorders are presented. Included are lichen sclerosus, squamous cell hyperplasia, vulvar intraepithelial neoplasia, vulvar Paget's disease, and squamous cell carcinoma. Current terminology, tumor measurements, and ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1992-04-01 00:00:00
abstract：:The unique properties of lasers create an enormous potential for specific therapy of skin diseases. As with any new device, the most efficacious and appropriate use requires an understanding of the mechanisms of light interaction with tissue as well as the properties of the laser itself. Modification of current lasers...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1993-01-01 00:00:00
