Molecular recognition in allergic contact dermatitis. The concept of double-headed haptens.

abstract：:Cosmeceuticals are topically applied products that are more than merely cosmetic, yet are not true drugs that have undergone rigorous placebo controlled studies for safety and efficacy. There are many review articles that outline the theoretical biologic and clinical actions of these cosmeceuticals and their various i...

journal_title：Dermatologic clinics

authors： Reszko AE,Berson D,Lupo MP

更新日期：2009-10-01 00:00:00

abstract：:Cyanoacrylates (CAs) were not widely adopted for medical use until recently because of lingering concerns regarding the initial tissue toxicities of the short-chain CAs. The medium-chain CAs, primarily butyl-cyanoacrylate, have been widely used in Europe and Canada for several decades and have gone a long way in dispe...

journal_title：Dermatologic clinics

authors： Eaglstein WH,Sullivan T

更新日期：2005-04-01 00:00:00

abstract：:Pemphigus vulgaris, which has multiple clinical variants, is an autoimmune blistering disorder of skin and mucous membranes, usually affecting the elderly, with a strong immunogenetic link. Immunologic studies of this disease have been productive in defining the pathophysiology of blister formation and the characteris...

journal_title：Dermatologic clinics

authors： Becker BA,Gaspari AA

更新日期：1993-07-01 00:00:00

abstract：:One may accomplish certain closures without tension or distortion using blunt liposuction cannula dissection with or without suction-assisted lipectomy. If closure cannot be accomplished with adequate undermining and an appropriate flap design, the surgeon may first aspirate fat to allow use of the focally expanded sk...

journal_title：Dermatologic clinics

authors： Field LM,Spinowitz AL

更新日期：1990-07-01 00:00:00

abstract：:The vitamin D endocrine system is known for its essential role in calcium homeostasis and bone metabolism, and induces cell differentiation, inhibits cell growth, controls other hormonal systems, and modulates the immune response. Vitamin D(3) is a prohormone that is taken up by diet or synthesized in ultraviolet radi...

journal_title：Dermatologic clinics

authors： Carlberg C,Seuter S

更新日期：2007-10-01 00:00:00

abstract：:The success of the Mohs procedure depends on the reliability of each step in the technique. Pitfalls in histologic preparation of the tissue specimens may occur during debulking, excising, orienting, creating the map, sectioning, inking, tissue flattening and freezing, cutting, slide fixation, staining, and mapping th...

journal_title：Dermatologic clinics

authors： Bouzari N,Olbricht S

更新日期：2011-04-01 00:00:00

abstract：:The varied histopathology of the reactive inflammatory vascular dermatoses requires close cooperation between the clinician and the pathologist. This article presents an overview of the histology of this group of dermatoses, including the figurate erythemas, the pigmented purpuric eruptions, urticaria and urticarial v...

journal_title：Dermatologic clinics

authors： Solomon AR Jr

更新日期：1985-01-01 00:00:00

abstract：:Patients with urogenital complaints are frequently encountered by family practitioners, gynecologists, and dermatologists. This review article provides practical information regarding normal anatomy and embryology of the vulva, followed by a summary of procedural techniques. The new classifications of vulvar inflammat...

journal_title：Dermatologic clinics

authors： Selim MA,Hoang MP

更新日期：2010-10-01 00:00:00

abstract：:Differences have been found among blacks, whites, Asians, and Hispanics in various areas of skin structure and function. Among them is the stratum corneum lipid (ceramide) content, which is highest in Asians, then Hispanics, then whites, and lowest in blacks. Melanosomal packaging and percutaneous absorption rates for...

journal_title：Dermatologic clinics

authors： Richards GM,Oresajo CO,Halder RM

更新日期：2003-10-01 00:00:00

abstract：:Tetracyclines are known to exhibit multiple significant anti-inflammatory actions. This article describes the mechanisms of this anti-inflammatory activity, such as inhibition of chemotaxis, granuloma formation, and protease. The article also discusses the effectiveness of tetracyclines in treating such diseases as ac...

journal_title：Dermatologic clinics

authors： Webster G,Del Rosso JQ

更新日期：2007-04-01 00:00:00

abstract：:Pharmaceutical manufacturing is one of the most financially lucrative industries in America due, in part, to massive marketing and advertising. The content of many symposia and medical journals as well as physician prescribing decisions seems to be influenced by the promotional efforts of pharmaceutical companies. In ...

journal_title：Dermatologic clinics

authors： Lober CW

更新日期：1993-04-01 00:00:00

abstract：:This brief survey has, it is hoped, helped to ease some of the anxiety associated with the management of complex autoimmune skin disorders. The main points to remember are that there are numerous therapeutic options for each disease. I like to think of this method of therapeutics as 'informed trial and error.' One doe...

journal_title：Dermatologic clinics

authors： Fivenson DP

更新日期：1997-10-01 00:00:00

abstract：:The excessive sweating of hyperhidrosis creates profound psychosocial, professional, and financial burdens on the individual sufferer; it contributes to impaired self-worth and self-efficacy, decreased satisfaction in all relationships, avoidance of specific careers, and increased expenditures on everything from cloth...

journal_title：Dermatologic clinics

authors： Pieretti LJ

更新日期：2014-10-01 00:00:00

abstract：:Acne vulgaris alters the normal skin physiology, impairing stratum corneum and transepidermal water loss. A male's normal skin physiologic state is different than a female's and may have implications when choosing treatment when the skin is altered in a disease state. Transepidermal water loss, pH, and sebum productio...

journal_title：Dermatologic clinics

authors： McCarty M

更新日期：2016-04-01 00:00:00

abstract：:The craniofacial and oral manifestations of the different epidermolysis bullosa (EB) types vary markedly in character and severity depending largely on the EB type. The tissues affected and the phenotypes displayed are closely related to the specific abnormal or absent proteins resulting from the causative genetic mut...

journal_title：Dermatologic clinics

authors： Wright JT

更新日期：2010-01-01 00:00:00

abstract：:There is a dearth of information on psoriasis in the tropics. Psoriasis occurs more frequently in northern geographic regions than in tropical climates. Its prevalence varies not only within the ethnic groups of a country but from country to country. A review of published studies on the natural history of psoriasis in...

journal_title：Dermatologic clinics

authors： Farber EM,Nall L

更新日期：1994-10-01 00:00:00

abstract：:Exanthematous eruptions, urticaria, photosensitivity, pigmentary problems, acne, alopecia, fixed drug eruptions, and lichenoid reactions are the most common dermatologic side effects associated with the administration of psychopharmacologic agents. The cutaneous findings associated with the various eruptions and the m...

journal_title：Dermatologic clinics

authors： Garnis-Jones S

更新日期：1996-07-01 00:00:00

abstract：:Many substances have historically been used to address facial soft tissue defects. Currently in the United States autologous fat and injectable bovine collagen are the most commonly utilized injectable fillers. Additionally, the judicious application of BOTOX in the upper face as well as neck has all but revolutionize...

journal_title：Dermatologic clinics

authors： Klein AW,Wexler P,Carruthers A,Carruthers J

更新日期：1997-10-01 00:00:00

abstract：:Rituximab is a chimeric, murine-human, monoclonal antibody against the CD20 antigen of B lymphocytes. It has been used off-label to treat and manage autoimmune and dermatologic diseases as an alternative or adjuvant therapy to systemic treatments. Due to cost, potential complications, and lack of data rituximab is use...

journal_title：Dermatologic clinics

authors： Daniel BS,Murrell DF,Joly P

更新日期：2011-10-01 00:00:00

abstract：:The management of onychomycosis using topical agents has improved with the introduction of ciclopirox and amorolfine nail lacquers; other topical agents may be less effective. The combination of a nail lacquer with an oral antifungal agent may further improve efficacy rates in certain clinical presentations (eg, among...

journal_title：Dermatologic clinics

authors： Gupta AK,Ryder JE,Baran R

更新日期：2003-07-01 00:00:00

abstract：:Ultraviolet (UV) radiation contributes to the development of skin cancer through direct and indirect DNA damage, production of reactive oxygen species, and local immunomodulation. The association between UV radiation and skin cancer has raised concern for the risk of carcinogenesis following phototherapy. The photocar...

journal_title：Dermatologic clinics

authors： Thompson KG,Kim N

更新日期：2020-01-01 00:00:00

abstract：:The leishmaniases are a group of zoonotic infections caused by protozoan parasites of the genus Leishmania. These infections produce a variety of different clinical diseases depending on the virulence or tropism of the parasite and differential host immune responses. Newly recognized clinical presentations, such as vi...

journal_title：Dermatologic clinics

authors： Magill AJ

更新日期：1995-07-01 00:00:00

abstract：:This article discusses ways to recognize and manage lymphomas and pseudolymphomas associated with drug exposure. Over the last 30 years, the classification of pseudolymphomas and lymphomas has undergone significant change, especially following the application of sophisticated immunostaining and gene rearrangement anal...

journal_title：Dermatologic clinics

authors： Albrecht J,Fine LA,Piette W

更新日期：2007-04-01 00:00:00

abstract：:Due to many factors, including parental anxiety, a child's inability to understand the necessity of a procedure and a child's unwillingness to cooperate, it can be much more challenging to perform dermatologic procedures in children. This article reviews pre-procedural preparation of patients and parents, techniques f...

journal_title：Dermatologic clinics

authors： Metz BJ

更新日期：2013-04-01 00:00:00

abstract：:For both NF and Albright's syndrome, the pathogenetic relationships between the various elements of the respective syndromes remain a mystery, and the importance of nontumorous endocrine abnormalities in neurofibromatosis has, in my opinion, been overstated. Nonetheless, the parallel between the two disorders is strik...

journal_title：Dermatologic clinics

authors： Riccardi VM

更新日期：1987-01-01 00:00:00

abstract：:Although the Mohs technique is most often applied to moderate and large lesions, with appropriate modifications it can also be applied to massive lesions. Reconstructive procedures after resection of large defects are also discussed. ...

journal_title：Dermatologic clinics

authors： Mattox DE,Skouge JW

更新日期：1989-10-01 00:00:00

abstract：:In this article, practical and clinical aspects of photoprotection are discussed with emphasis on topical sunscreens. Protection against the adverse effects of sunlight includes prevention of the following: sunburn in normal individuals; acute phototoxic and photoallergic reactions; chronic skin damage (dermatoheliosi...

journal_title：Dermatologic clinics

authors： Pathak MA

更新日期：1986-04-01 00:00:00

abstract：:Chloracne is a rare but important acneiform eruption often associated with the ingestion of chlorinated phenolic agents such as dioxins with subsequent toxicity from these chemicals. Clinically, chloracne can be distinguished from acne vulgaris by the distribution and appearance of the lesions and by taking a detailed...

journal_title：Dermatologic clinics

authors： Zugerman C

更新日期：1990-01-01 00:00:00

abstract：:Countries in the so-called "Western" world, especially in Europe, witnessed a dramatic change in ethnic backgrounds of their populations starting in the last decennia of the last century. This had repercussions on various aspects of our society, including medical practice. In dermatology for instance, pigmentary disor...

journal_title：Dermatologic clinics

authors： van der Veen JP

更新日期：2007-07-01 00:00:00

abstract：:Involvement of the genitourinary tract has been described in many different types of epidermolysis bullosa (EB). Pathology may be broadly divided into problems resulting in obstruction, that may in turn lead to hydroureter or hydronephrosis, or disease primarily affecting the renal parenchyma. Left unrecognized and un...

journal_title：Dermatologic clinics

authors： Almaani N,Mellerio JE

更新日期：2010-04-01 00:00:00