Prospects for controlling cervical cancer at the turn of the century.

Abstract:

:Cervical cancer morbidity and mortality have decreased substantially during the last 50 years mostly due to successful organized or opportunistic screening with Pap cytology in high and middle income countries. In many low income countries Pap cytology screening is yet to be effectively implemented or has failed to reduce cervical cancer rates to an appreciable extent. The fact that infection with certain human papillomavirus (HPV) types is now recognized as a necessary cause of this disease has led to new research fronts on prevention of cervical cancer. Testing for HPV DNA has shown great promise as a screening tool with better sensitivity but somewhat lower specificity than Pap cytology. In combination with the latter, HPV testing has the potential to improve the negative predictive value of cytology, thus allowing for increased testing intervals, which would lower program costs with acceptable safety. Advances in cytology processing and automation have also led to new screening approaches that are increasingly gaining acceptance in high and middle income countries. For low income countries, visual inspection with acetic acid has proven to be an effective alternative to conventional Pap cytology, especially in settings where no screening programs have been implemented. Concerning primary prevention of cervical cancer, recent research on the safety and efficacy of candidate prophylactic vaccines against HPV have shown very promising results with nearly 100% efficacy in preventing persistent infections and development of cervical cancer precursors. However, policy makers are strongly cautioned to avoid deferring decisions concerning the implementation of cervical cancer screening under the expectation that a successful vaccine could obviate the need for secondary prevention strategies. This paper is available too at: http://www.insp.mx/salud/index.html.

journal_name

Salud Publica Mex

journal_title

Salud publica de Mexico

authors

Franco EL,Duarte-Franco E,Ferenczy A

doi

10.1590/s0036-36342003000900011

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

S367-75

eissn

0036-3634

issn

1606-7916

journal_volume

45 Suppl 3

pub_type

杂志文章,评审
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    journal_title:Salud publica de Mexico

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    authors: Folch-Mas A,Cortés-Ruiz MJ,Vicens Calderón P,Martínez-Leal R

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  • [Glazed pottery as a risk factor in lead exposure].

    abstract::The purpose of this study was to determine if the use of "earthenware dishes" is associated with high blood lead levels in children. Measurements of lead in blood were done in 169 school-children. Of this sample 100 children were selected: 50 of them with the lowest concentration of lead in blood and 50 with the highe...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Vega-Franco L,Alvear G,Meza-Camacho C

    更新日期:1994-03-01 00:00:00

  • [Stunting and emaciation in children under 5 in distinct regions and strata in Mexico].

    abstract::Data from a National Nutrition Survey conducted in 1988 in a probability sample of 13,236 households and 17,426 children under five, representative at the national level and for four regions (North, Center, South, and Mexico City), were analyzed. Risks for wasting and stunting and odds ratios were obtained by region, ...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Rivera-Dommarco J,González-Cossío T,Flores M,Hernández-Avila M,Lezana MA,Sepúlveda-Amor J

    更新日期:1995-03-01 00:00:00

  • [A decade of lead monitoring in schoolchildren in the metropolitan area of Monterrey NL, Mexico].

    abstract:OBJECTIVE:To establish the blood lead concentration and associated risk factors in schoolchildren during 1998 and 2008. MATERIALS AND METHODS:A blood lead screening was conducted in schoolchildren of 6-12 years of age, enrolled in 17 elementary schools of the metropolitan area of Monterrey, México, during 1998 and 200...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Santos-Guzmán J,Madrigal-Ávila C,Hernández-Hernández JA,Mejía-Velázquez G,Eraña-Rojas IE,Elizondo-Montemayor L,Villela L

    更新日期:2014-11-01 00:00:00

  • Tuberculosis stigma and perceptions in the US-Mexico border.

    abstract:OBJECTIVE:To examine the experiences and perspectives on the disease and stigma from the vantage point of the persons affected by TB in El Paso, Texas, and Juárez, México to inform research on health-related stigma and interventions. MATERIALS AND METHODS:Semi-structured interviews to study TB-related stigma and the i...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:10.21149/spm.v55s4.5155

    authors: Moya EM,Lusk MW

    更新日期:2013-01-01 00:00:00

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    abstract:OBJECTIVE:To analyse who are the people giving psychological and instrumental support to the elderly, as well as potential differences among these caregivers according to age and/or sex of the elderly. MATERIAL AND METHODS:Manheim interview for social support was used to gather the opinions of 101 elder people (>65 ye...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:10.1590/s0036-36342007000600007

    authors: Meléndez-Moral JC,Tomás-Miguel JM,Navarro-Pardo E

    更新日期:2007-11-01 00:00:00

  • [Recombinant therapeutic vaccines against cancer of the uterine cervix].

    abstract::Several mechanism to evade the immune system are induced during cervical cancer development, including the decrease of expression of class I HLA molecules and secretion of specific cytokines by tumoral cells. Consequently, the stimulation of cytotoxic (CTL) and helper (TH) T lymphocytes, as well as the natural killer ...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章,评审

    doi:

    authors: Berumen J,Villegas N

    更新日期:1997-07-01 00:00:00

  • Factors affecting acceptance of complete immunization coverage of children under five years in rural Bangladesh.

    abstract:OBJECTIVE:This article establishes the hypothesis that predisposing, enabling and household needs influence the complete vaccination status of children. MATERIAL AND METHODS:Data from the 2004 Bangladesh Demographic and Health Survey (N= 3530) was used. The data was analyzed using descriptive and multiple logistic reg...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:10.1590/s0036-36342010000200005

    authors: Rahman M,Obaida-Nasrin S

    更新日期:2010-03-01 00:00:00

  • [Violence scale and severity index: a methodological proposal for measuring violence by the partner in Mexican women].

    abstract:OBJECTIVE:To construct and validate a scale to assess violence by the male partner against women. An index of severity of the emotional and physical damage was also designed to assess the intensity of the violent actions against women. MATERIAL AND METHODS:The sample consisted of a total of 26 042 women who participat...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:10.1590/s0036-36342006000800002

    authors: Valdez-Santiago R,Híjar-Medina MC,Salgado de Snyder VN,Rivera-Rivera L,Avila-Burgos L,Rojas R

    更新日期:2006-01-01 00:00:00

  • [Adequacy of the diet served to Tarahumara children in indigenous boarding schools of northern Mexico].

    abstract:OBJECTIVE:To assess the adequacy and variability of the diet served to Tarahumara children in indigenous boarding schools. MATERIAL AND METHODS:Records of food and drinks served for meals, weighed daily, were obtained from Monday through Friday for 10 consecutive weeks in two selected boarding schools. Nutrient intake...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:10.1590/s0036-36342010000100005

    authors: Monárrez-Espino J,Béjar-Lío GI,Vázquez-Mendoza G

    更新日期:2010-01-01 00:00:00

  • [An approach to the study of health services costs in Mexico].

    abstract:OBJECTIVE:To approach the cost analysis of the health services for eight tracer conditions, in three institutions of the public sector and in five of the private sector. MATERIAL AND METHODS:First, production functions and inputs required for standard case-management of each tracer condition were identified. Subsequen...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Arredondo A,Damián T,de Icaza E

    更新日期:1995-09-01 00:00:00

  • [Children exposure to lead in contaminated sites].

    abstract:OBJECTIVE:To assess the exposure to lead in children living in various types of contaminated sites. MATERIALS AND METHODS:The study was conducted from June 2008 to December 2009 at four sites in Mexico: Avalos metallurgical, Chihuahua; Morales metallurgical, San Luis Potosí (SLP); Trinidad pottery area, Tlaxcala and C...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:10.1590/s0036-36342012000400008

    authors: Flores-Ramírez R,Rico-Escobar E,Núñez-Monreal JE,García-Nieto E,Carrizales L,Ilizaliturri-Hernández C,Díaz-Barriga F

    更新日期:2012-07-01 00:00:00

  • [Evidence is good for your health system: policy reform to remedy catastrophic and impoverishing health spending in Mexico].

    abstract::Absence of financial protection in health is a recently diagnosed "disease" of health systems. The most obvious symptom is that families face economic ruin and poverty as a consequence of financing their health care. Mexico was one of the first countries to diagnose the problem, attribute it to lack of financial prote...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Knaul FM,Arreola-Ornelas H,Méndez-Carniado O,Bryson-Cahn C,Barofsky J,Maguire R,Miranda M,Sesma S

    更新日期:2007-01-01 00:00:00

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    abstract::This document summarizes the most relevant epidemiologic characteristics of infant and child mortality in Latin America. The gap in infant mortality rates between Latin America and the developed countries is wide and appears to be increasing. In the developed countries, 980 of each 1000 infants survive to the age of...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Behm-Rosas H

    更新日期:1988-05-01 00:00:00

  • [Inactivation of aflatoxin B1 and aflatoxicol through traditional "nixtamalización" of corn and their regeneration by acidification of corn dough].

    abstract:OBJECTIVE:To ratify the effect of traditional "nixtamalización" upon aflatoxin in corn, to identify the residual compound in dough, to evaluate its toxicity, and to verify the effect of acidic treatment on the regeneration of aflatoxin. MATERIAL AND METHODS:Corn with and without aflatoxin was treated separately with l...

    journal_title:Salud publica de Mexico

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    doi:10.1590/s0036-36342005000500007

    authors: Anguiano-Ruvalcaba GL,Verver y Vargas-Cortina A,Guzmán-de Peña D

    更新日期:2005-09-01 00:00:00

  • [Quality assurance programs through the accreditation of hospitals in Latin America and the Caribbean].

    abstract::The majority of the approximately 14,000 hospitals in Latin America and the Caribbean face enormous challenges to live up to the basic prepositions of quality assurance in health care. If methods of quality control in medical education and hospitals are not implemented soon in Latin America, we will face, in the very ...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: de Moraes Novaes H

    更新日期:1993-05-01 00:00:00

  • [Prevalence of anti-Chlamydia trachomatis and anti-Neisseria gonorrhoeae antibodies in Mexican populations].

    abstract:OBJECTIVE:To estimate the prevalence of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection in groups of individuals at different risks of sexually transmitted infections (STI). MATERIAL AND METHODS:Between January 1992 and December 1993, a cross-sectional multicentric study was carried out at the Inst...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章,多中心研究,评审

    doi:

    authors: Cravioto Mdel C,Matamoros O,Villalobos-Zapata Y,Peña O,García-Lara E,Martínez M,Castelo J,Sifuentes-Osornio J

    更新日期:2003-01-01 00:00:00

  • [The epidemiological surveillance of dengue in Mexico].

    abstract::The clinical behavior of dengue fever in Mexico has changed, now with the occurrence of hemorrhagic cases. In response to the emergence of such cases, a specific epidemiologic surveillance system has been designed and implemented. This system includes the means to monitor the factors involved in the evolution of the d...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Montesano-Castellanos R,Ruiz-Matus C

    更新日期:1995-01-01 00:00:00

  • Prevention of cardiovascular disease based on lipid lowering treatment: a challenge for the Mexican health system.

    abstract:OBJECTIVE:To estimate the percentage of Mexican adults that may require lipid-lowering treatment according to National Cholesterol Education Program-III guidelines, using data from the National Health and Nutrition Survey 2006 (ENSANut 2006). MATERIAL AND METHODS:Information was obtained from 4 040 subjects aged 20 to...

    journal_title:Salud publica de Mexico

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    doi:10.1590/s0036-36342010000700009

    authors: Gómez-Pérez FJ,Rojas R,Villalpando S,Barquera S,Rull J,Aguilar-Salinas CA

    更新日期:2010-01-01 00:00:00

  • [Electrocardiographic changes and cardiovascular risk factors in patients with type-2 diabetes].

    abstract:OBJECTIVE:To determine the most frequent alterations in rhythm and cardiac conduction in patients with type 2 diabetes without previous cardiopathy, and to establish the association of this disease with cardiovascular risk factors. MATERIAL AND METHODS:Subjects with type 2 diabetes, without cardiopathy antecedents wer...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Rodríguez-Morán M,Guerrero-Romero F

    更新日期:1999-01-01 00:00:00

  • Secondhand smoke: facts and lies.

    abstract::Mexico ratified the Framework Convention for Tobacco Control in 2004 and is obligated to move forward with implementing its provisions, including Article 8 (Protection from exposure to tobacco smoke). The country has already faced opposition from the tobacco industry. This paper addresses industry tactics against toba...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:10.1590/s0036-36342008000500016

    authors: Samet JM

    更新日期:2008-09-01 00:00:00

  • [Maternal overweight and obesity in Mexican school-age children. National Nutrition Survey, 1999].

    abstract:OBJECTIVE:To assess the effects of maternal overweight and obesity as risk factors for overweight and obesity in Mexican school-age children (5 to 11 years old) who participated in the National Nutrition Survey 1999 (NNS-99). MATERIAL AND METHODS:Information obtained by the NNS-99 was used to evaluate the relationship...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:10.1590/s0036-36342005000600009

    authors: Flores M,Carrión C,Barquera S

    更新日期:2005-11-01 00:00:00

  • Study of cutaneous leishmaniasis in the State of Campeche (Yucatan Peninsula), Mexico, over a period of two years.

    abstract:OBJECTIVE:To study cutaneous leishmaniasis (CL), in the Calakmul municipality of the Campeche State, during two years. MATERIALS AND METHODS:Individuals with skin lesions were evaluated. Aspirates taken from the lesions were cultured, PCR was performed to diagnose the Leishmania species. RESULTS:The culture detected ...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:10.21149/spm.v57i1.7403

    authors: Hernández-Rivera MP,Hernández-Montes O,Chiñas-Pérez A,Batiza-Avelar JM,Sánchez-Tejeda G,Wong-Ramírez C,Monroy-Ostria A

    更新日期:2015-01-01 00:00:00

  • [Successful aging: conceiving the aging process from a more positive perspective].

    abstract::In 1987 John Rowe introduced the concept of Successful Aging. This is a new point of view, and its appearance has been followed by a growing amount of literature and research on the subject. The author reviews the concept of Successful Aging and some of the results of his experimental work. The growing numbers of peop...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Vellas P

    更新日期:1996-11-01 00:00:00

  • [Pharmacological therapy compliance in diabetes].

    abstract:OBJECTIVE:To establish the frequency of compliance to pharmacological therapy, and to identify non-compliance factors, in relation to metabolic control on patients with type-II diabetes mellitus. MATERIAL AND METHODS:A comparative cross-sectional study was conducted between 1997 and 1998, among 150 type-II diabetic pa...

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Durán-Varela BR,Rivera-Chavira B,Franco-Gallegos E

    更新日期:2001-05-01 00:00:00

  • [The clinico-epidemiological characteristics of cholera patients in Mexico City].

    abstract:OBJECTIVE:To compare the clinical and epidemiological characteristics of cholera patients and patients with diarrhea of different etiology (controls), treated at Mexican Institute of Social Security medical units in northeast Mexico City, from 1995 to 1998. MATERIAL AND METHODS:Cross-sectional analytical study design....

    journal_title:Salud publica de Mexico

    pub_type: 杂志文章

    doi:

    authors: Vilchis-Guizar AE,Uribe-Márquez S,Pérez-Sánchez PL

    更新日期:1999-11-01 00:00:00

  • Evaluation of Mexico's low cancer mortality using two national death registries.

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    pub_type: 杂志文章

    doi:10.21149/10635

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  • [Validation of a self-efficiency scale for the prevention of AIDS among adolescents].

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    doi:

    authors: López-Rosales F,Moral-de la Rubia J

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    doi:

    authors: Aspe P,Beristáin J

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