Abstract:
BACKGROUND:The major difficulty in postoperative care in patients after craniotomy is to distinguish the intracranial deficits from the residual effect of general anesthesia. In present study, we used cerebral state index (CSI) monitoring in patients after craniotomy with delayed recovery, and evaluated the prediction probability of CSI for long-term postoperative unconsciousness. METHODS:We enrolled 57 consecutive adult patients admitted to neurosurgical intensive care unit (NICU) after elective craniotomy with delayed recovery. CSI was continuously monitored for 6 hours after admission. Patient's level of consciousness was followed up for 24 hours. According to whether obeyed verbal command, patients were divided into awaken group and non-awaken group. CSI values were compared between the two groups. Prediction probability (PK) was calculated to determine the probability of CSI in predicting unconsciousness 24 hours after operation. RESULTS:In awaken group (n = 51), CSI increased significantly after the 2nd NICU admitted hour (P < 0.05). At each time point, CSI values in awaken group were significantly higher than those in non-awaken group (n = 6) (P < 0.05). The values of PK (SE) for CSI in the first 6 admitted hours ranged from 0.94 (0.06) to 0.99 (0.02). CONCLUSIONS:In patients after craniotomy with delayed recovery, CSI monitoring in early postoperative hours had high prediction probability for long-term unconsciousness. CSI monitoring may be a reliable objective method to predict level of consciousness after elective craniotomy.
journal_name
BMC Neuroljournal_title
BMC neurologyauthors
Xu M,Lei YN,Zhou JXdoi
10.1186/1471-2377-11-15subject
Has Abstractpub_date
2011-01-27 00:00:00pages
15issn
1471-2377pii
1471-2377-11-15journal_volume
11pub_type
杂志文章相关文献
BMC Neurology文献大全abstract:BACKGROUND:Assessment of subjective quality of life (QOL) of persons with multiple sclerosis (MS) could facilitate the detection of psychosocial aspects of disease that may otherwise go unrecognized. The objectives of the study were to (i) compare the QOL ratings of relapsing remitting (RRMS) and progressive (PMS) type...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-7-31
更新日期:2007-09-18 00:00:00
abstract:BACKGROUND:The disease burden of human immunodeficiency virus (HIV)--acquired immunodeficiency syndrome (AIDS) is highest in sub-Saharan Africa but there are few studies on the associated neurocognitive disorders in this region. The objectives of this study were to determine whether Western neuropsychological (NP) meth...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-10-60
更新日期:2010-07-13 00:00:00
abstract:BACKGROUND:Ropinirole prolonged release (RPR) is a once-daily formulation. However, there may be individual pharmacokinetic differences so that multiple dosing may be preferred in some individuals. This study compares once-daily and twice-daily RPR in patients with Parkinson's disease. METHODS:This study was an open-l...
journal_title:BMC neurology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1186/1471-2377-13-113
更新日期:2013-09-02 00:00:00
abstract:BACKGROUND:Study aimed at investigation of pathogenic role and prognostic value of several selected cerebrospinal fluid acute phase factors that can reflect the severity of ischemic brain damage. METHODS:Ninety five acute ischemic stroke patients were investigated. Ischemic region visualized at the twenty fourth hour ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-11-41
更新日期:2011-03-30 00:00:00
abstract:BACKGROUND:Migraine is a highly prevalent disorder. The disability provoked by its attacks results in suffering as well as considerable economic and social losses. The objective of migraine acute treatment is to restore the patient to normal function as quickly and consistently as possible. There are numerous drugs ava...
journal_title:BMC neurology
pub_type: 杂志文章,评审
doi:10.1186/1471-2377-4-4
更新日期:2004-01-28 00:00:00
abstract:BACKGROUND:We imaged the corticospinal tract (CST) and corticoreticular pathway (CRP) using diffusion tensor tractography (DTT) to evaluate the cause of muscle weakness in a patient who was exposed to high-voltage electricity. CASE PRESENTATION:A 39-year-old man presented with quadriparesis after high-voltage electric...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-020-01707-2
更新日期:2020-04-13 00:00:00
abstract:BACKGROUND:The aim of this study was to examine the stability and relative validity (RV) of the Neuromuscular Disease Impact Profile (NMDIP) using criterion-related groups. In a previous study the NMDIP-scales showed good internal consistency, convergent and discriminant validity. Known-groups analysis showed that the ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-017-0866-6
更新日期:2017-05-11 00:00:00
abstract:BACKGROUND:The clinical impact of neutralizing antibodies against interferon-beta (NAb) is controversial. Their presence can lead to a decrease in interferon-beta (IFNβ) efficacy. Fatigue reported in patients with multiple sclerosis (MS) may be associated with an unfavorable clinical course. We conducted a prospective ...
journal_title:BMC neurology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12883-014-0215-y
更新日期:2014-11-30 00:00:00
abstract:BACKGROUND:Primary microcephaly is defined as reduced occipital-frontal circumference noticeable before 36 weeks of gestation. Large amount of insults might lead to microcephaly including infections, hypoxia and genetic mutations. More than 16 genes are described in autosomal recessive primary microcephaly. However, th...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-020-01643-1
更新日期:2020-02-15 00:00:00
abstract:BACKGROUND:Intravenous thrombolysis has been recently introduced in Nepal for the management of acute ischemic stroke. Pre-hospital delay is one of the main reasons that hinder thrombolytic therapy. The objective of this study was to evaluate the status of prehospital delay and thrombolysis in Nepal. METHODS:Data were...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-019-1378-3
更新日期:2019-07-09 00:00:00
abstract:BACKGROUND:Admission hyperglycemia (HG) has been associated with worse outcomes among acute stroke patients. A better understanding and awareness of the potentially adverse influence of hyperglycemia on the clinical outcome of acute stroke patients would help to provide guidance for acute stroke management and preventi...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-019-1578-x
更新日期:2019-12-27 00:00:00
abstract:BACKGROUND:Road traffic accidents are known to be the main cause of traumatic brain injury (TBI). TBI is also a leading cause of death and disability. This study, by means of the idiographic approach (single-case experimental designs using multiple-baseline designs), has examined whether methylphenidate (MPH - trade na...
journal_title:BMC neurology
pub_type: 临床试验,杂志文章
doi:10.1186/s12883-020-01663-x
更新日期:2020-03-19 00:00:00
abstract:BACKGROUND:The Observational Skills Assessment Score (OSAS) measures amount and quality of use of the affected hand in children with unilateral Cerebral Palsy (CP) in bimanual activities and could therefore be a valuable addition to existing assessment tools. The OSAS consists of tasks that are age appropriate and requ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-13-152
更新日期:2013-10-21 00:00:00
abstract:BACKGROUND:The Stroke burden is increasing in many populations where health institutions may experience more patients. We wanted to examine whether incidence rates and absolute number of hospitalized stroke patients remained stable in Denmark during a 13 years period where exposure to major stroke risk factors decrease...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-13-156
更新日期:2013-10-30 00:00:00
abstract:BACKGROUND:Spinal cord infarction (SCI) is rarely caused by vertebral artery dissection (VAD), which is an important cause of posterior circulation stroke in young and middle-aged patients. We report the case of a middle-aged patient without obvious risk factors for atherosclerosis who had SCI from right VAD. CASE PRE...
journal_title:BMC neurology
pub_type: 杂志文章,评审
doi:10.1186/s12883-019-1559-0
更新日期:2019-12-12 00:00:00
abstract:BACKGROUND:Friedreich ataxia is a neurological disease originating from an iron-sulfur cluster enzyme deficiency due to impaired iron handling in the mitochondrion, aconitase being particularly affected. As a mean to counteract disease progression, it has been suggested to chelate free mitochondrial iron. Recent years ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-8-20
更新日期:2008-06-16 00:00:00
abstract:BACKGROUND:The aim of this study was to examine the hospital readmissions in a 10 year follow-up of a stroke cohort previously studied for acute and subacute complications and to focus on their frequency, their causes and their timing. METHODS:The hospital records of 243 patients, 50% of a cohort of 489 patients acute...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-017-0897-z
更新日期:2017-06-19 00:00:00
abstract:BACKGROUND:Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a clinically heterogeneous disorder characterized by epileptic seizures, psychosis, dyskinesia, consciousness impairments, and autonomic instability. Symptoms are always various. Sometimes it presents in milder or incomplete forms. We report 4 cases ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0787-9
更新日期:2017-01-05 00:00:00
abstract:BACKGROUND:Different apoptosis pathways activate caspase-3. In a study involving 27 patients with traumatic brain injury (TBI), higher caspase-3 levels were found in contusion brain tissue resected from non-survivors than from survivors. The objective of this study was to determine whether there is an association in TB...
journal_title:BMC neurology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12883-015-0485-z
更新日期:2015-11-06 00:00:00
abstract:BACKGROUND:Cardioembolic stroke (CES) due to atrial fibrillation (AF) is associated with high stroke mortality. Oral anticoagulation (OAC) reduces stroke mortality, however, the impact of OAC-administration during hospital stay post ischemic stroke on mortality is unclear. We determined whether the timing of OAC initia...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-014-0199-7
更新日期:2014-10-08 00:00:00
abstract:BACKGROUND:Recent consensus guidelines recommend pregabalin as a first-tier treatment for painful diabetic peripheral neuropathy (DPN). We evaluated the efficacy of pregabalin 600 mg/d (300 mg dosed BID) versus placebo for relieving DPN-associated neuropathic pain, and assessed its safety using objective measures of ne...
journal_title:BMC neurology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/1471-2377-8-33
更新日期:2008-09-16 00:00:00
abstract:BACKGROUND:THK5351 and flortaucipir tau ligands have high affinity for paired helical filament tau, yet diverse off-target bindings have been reported. Recent data support the hypothesis that THK5351 binds to monoamine oxidase B (MAO-B) expressed from reactive astrocytes and that flortaucipir has an affinity toward MAO...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-019-1434-z
更新日期:2019-08-29 00:00:00
abstract::The advent of early absorption, distribution, metabolism, excretion, and toxicity (ADMET) screening has increased the attrition rate of weak drug candidates early in the drug-discovery process, and decreased the proportion of compounds failing in clinical trials for ADMET reasons. This paper reviews the history of ADM...
journal_title:BMC neurology
pub_type: 杂志文章,评审
doi:10.1186/1471-2377-9-S1-S1
更新日期:2009-06-12 00:00:00
abstract:BACKGROUND:In adults, the anastomosis between carotid and vertebrobasilar arteries is usually the posterior communicating artery, sometimes the primitive trigeminal artery. In this case, the basilar artery fed the internal carotid artery through the pontine-to-tentorial artery anastomosis after severe stenosis from tra...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-020-01651-1
更新日期:2020-03-17 00:00:00
abstract:BACKGROUND:Hypertrophic pachymeningitis (HP) is a rare disorder that involves localized or diffuse thickening of the dura mater. HP is associated with various inflammatory, infectious, and malignant diseases, such as rheumatic arthritis, sarcoidosis, anti-neutrophil cytoplasmic antibody-associated vasculitis, IgG4-rela...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-020-1600-3
更新日期:2020-01-09 00:00:00
abstract:BACKGROUND:Progressive Supranuclear Palsy (PSP) is the most frequent form of atypical Parkinsonism. Although there is preliminary evidence for the benefits of gait rehabilitation, balance training and oculomotor exercises in PSP, the quality of reporting of exercise therapies appears mixed. The current investigation ai...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-019-1539-4
更新日期:2019-11-29 00:00:00
abstract:BACKGROUND:Cerebral amyloid angiopathy (CAA) refers to the deposition of β-amyloid (Aβ) peptides in the wall of brain vasculature, commonly involving capillaries and arterioles. Also being considered a part of CAA is the Aβ deposition in leptomeninge. The cellular origin of angiopathic Aβ and the pathogenic course of C...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-015-0327-z
更新日期:2015-05-02 00:00:00
abstract:BACKGROUND:Migraine and Attention Deficit and Hyperactivity Disorder (ADHD) have been found to be associated in child and adolescent cohorts; however, the association has not been assessed in adults or otherwise healthy population. Assessing the comorbidity between ADHD and migraine may clarify the etiopathology of bot...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-018-1149-6
更新日期:2018-10-16 00:00:00
abstract:BACKGROUND:Only a few case reports and case series dealing with oral and dental health care are available in literature until now. The aim of the present pilot study was to determine the status of dental health in comparison to matched controls and to heighten the neurologists' and dentists' awareness of the oral aspec...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-13-114
更新日期:2013-09-03 00:00:00
abstract:BACKGROUND:Seizures are one of the most important neurologic complications of human immuno-deficiency virus (HIV)-negative cryptococcal meningitis. A better understanding of the risk associated factors can help predict those who will require treatment. METHODS:This 22-year retrospective study enrolled 180 patients. Pr...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-014-0208-x
更新日期:2014-10-13 00:00:00