Abstract:
BACKGROUND:Precise noninvasive evaluation of pulmonary artery (PA) morphology is extremely important for medical and surgical management of patients with cyanotic heart disease. In this study, the accuracy of two-dimensional echocardiography combined with color Doppler flow mapping to assess the size, stenosis, and atresia of the major PA branches was examined using a new parasternal approach. METHODS AND RESULTS:With the use of right and left high parasternal windows, we visualized each of the major portions along the right (R-PA) and left (L-PA) pulmonary arteries in 45 of the 47 examinations (96%) in 38 patients with cyanotic heart disease. The patients were between 13 days and 20 years old (mean age, 2.9 years). The internal diameters of the major PA branches were measured at three points along the R-PA (the proximal, mid, and distal portions) and at the proximal and distal portions on the L-PA in systole by both two-dimensional echocardiography and angiography. In addition, the diameter of the stenosis in the PA branch was measured. These PA values as determined by two-dimensional echocardiography correlated well with those obtained by angiography (r = .95 to .97). By two-dimensional echocardiography with color Doppler flow mapping, 17 of 19 lesions with stenoses or atresia of the major PA branches were predicted as defined by angiography (sensitivity, 89.5%; specificity, 100%). Differences between the distal parts of the L-PA and R-PA of > 30% in diameter were determined by angiography in 15 examinations and by two-dimensional echocardiography in 12 examinations (sensitivity, 80%; specificity, 97.4%). CONCLUSIONS:Our technique permits noninvasive evaluation of the size, stenoses, and atresia of the major portions of the PA branches in patients with cyanotic heart disease both before and after surgery.
journal_name
Circulationjournal_title
Circulationauthors
Hiraishi S,Misawa H,Hirota H,Agata Y,Horiguchi Y,Fujino N,Yi LH,Yashiro K,Nakae S,Kawada Mdoi
10.1161/01.cir.89.3.1306subject
Has Abstractpub_date
1994-03-01 00:00:00pages
1306-16issue
3eissn
0009-7322issn
1524-4539journal_volume
89pub_type
杂志文章相关文献
CIRCULATION文献大全abstract::A technique is described to control recurrent or sustained supraventricular tachycardia associated with rapid ventricular rates following open heart surgery. The technique utilizes a pair of temporarily implanted atrial epicardial wire electrodes to pace the heart. In one group of patients with recurrent atrial flutte...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.54.2.245
更新日期:1976-08-01 00:00:00
abstract::The indication for prophylactic temporary and permanent pacing during acute myocardial infarction (MI) complicated by bundle branch block is high risk of progression via a Type II pattern to second or third degree (high degree) AV block during hospitalization or follow-up. In this study, determinants of high degree AV...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.58.4.689
更新日期:1978-10-01 00:00:00
abstract:BACKGROUND:Chronic heart failure is associated with endothelial dysfunction including impaired endothelium-mediated, flow-dependent dilation (FDD). Since endothelial function is thought to play an important role in coordinating tissue perfusion and modulating arterial compliance, interventions to improve endothelial dy...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.93.2.210
更新日期:1996-01-15 00:00:00
abstract:BACKGROUND:There are several potential physiological differences between the atriopulmonary (AP) and the total cavopulmonary connection (TCPC) Fontan circulations. Studies suggest that the TCPC reduces energy loss due to turbulence and may have more dependence on respiratory movement for pulmonary blood flow. We compar...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.91.2.372
更新日期:1995-01-15 00:00:00
abstract:BACKGROUND:Female sex is an independent risk factor for torsade de pointes in long-QT syndrome. In women, QT interval and torsade de pointes risk fluctuate dynamically during the menstrual cycle and pregnancy. Accumulating clinical evidence suggests a role for progesterone; however, the effect of progesterone on cardia...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.107.702407
更新日期:2007-12-18 00:00:00
abstract:BACKGROUND:The pathophysiology of mental stress-induced myocardial ischemia, which occurs at lower heart rates than during physical stress, is not well understood. METHODS AND RESULTS:The Psychophysiological Investigations of Myocardial Ischemia Study (PIMI) evaluated the physiological and neuroendocrine functioning i...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.94.10.2402
更新日期:1996-11-15 00:00:00
abstract:BACKGROUND:Administration of angiogenic factors stimulates neovascularization in ischemic tissues. However, there is no evidence that angiogenesis can be induced in normoperfused skeletal muscles. We tested the hypothesis that adenovirus-mediated intramuscular (IM) gene transfer of the 121-amino-acid form of vascular e...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.102.5.565
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:We have previously described two distinct mutations in the beta-myosin heavy chain gene with markedly different clinical presentations and outcome: The 908Leu-->Val mutation was associated with a low disease penetrance and a benign prognosis. In contrast, the 403Arg-->Gln mutation in a Caucasian kindred was ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.89.1.22
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Flavone-8-acetic acid (FAA; [Flavonoid]), an adjuvant antitumor drug, inhibits ristocetin-induced aggregation of human platelets. The effect of FAA on platelet-dependent thrombosis was studied in vivo in the porcine carotid artery after deep arterial injury by balloon angioplasty. METHODS AND RESULTS:(111)I...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.101.3.324
更新日期:2000-01-25 00:00:00
abstract:BACKGROUND:Clinical cardiac volumetric measurement techniques are essential for assessing cardiac performance but produce significant inaccuracies in extrapolation of the volume of a three-dimensional (3D) object from two-dimensional images and lack the ability to associate cardiac electrical and mechanical activities....
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.96.10.3672
更新日期:1997-11-18 00:00:00
abstract:BACKGROUND:Elevated levels of high-sensitivity C-reactive protein (hsCRP) are associated with higher risk of adverse outcomes in patients at risk for or with established coronary artery disease. Retrospective analyses suggest that this risk may be modified with statin therapy. However, a role for hsCRP in monitoring th...
journal_title:Circulation
pub_type: 杂志文章,随机对照试验
doi:10.1161/CIRCULATIONAHA.106.628909
更新日期:2006-07-25 00:00:00
abstract:BACKGROUND:PCTP (phosphatidylcholine transfer protein) regulates the intermembrane transfer of phosphatidylcholine. Higher platelet PCTP expression is associated with increased platelet responses on activation of protease-activated receptor 4 thrombin receptors noted in black subjects compared with white subjects. Litt...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.116.023711
更新日期:2017-09-05 00:00:00
abstract::Children with congenital aortic stenosis have "excessive" left ventricular hypertrophy with reduced resting systolic wall stress that allows for supernormal ejection performance. If aortic stenosis is uncorrected, this pattern persists until adulthood. The effect of removing the aortic pressure gradient on left ventri...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.78.6.1358
更新日期:1988-12-01 00:00:00
abstract:BACKGROUND:The genetic basis of left ventricular (LV) image-derived phenotypes, which play a vital role in the diagnosis, management, and risk stratification of cardiovascular diseases, is unclear at present. METHODS:The LV parameters were measured from the cardiovascular magnetic resonance studies of the UK Biobank. ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.119.041161
更新日期:2019-10-15 00:00:00
abstract::Patients with systemic morphological right ventricles (RVs), including congenitally corrected transposition of the great arteries and dextro-transposition of the great arteries with a Mustard or Senning atrial baffle repair, have a high likelihood of developing systemic ventricular dysfunction. Unfortunately, there ar...
journal_title:Circulation
pub_type: 杂志文章,meta分析
doi:10.1161/CIR.0000000000000604
更新日期:2019-04-02 00:00:00
abstract:BACKGROUND:The cross-talk between vascular endothelial growth factor (VEGF)-A, angiopoietin (Ang), and VE-cadherin coregulates endothelial cell (EC) survival. Cardiac expression of VEGF-A but not its receptor KDR is blunted in dilated cardiomyopathy (DCM). Whether VE-cadherin/Ang function is affected in DCM is unknown....
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.CIR.0000091085.12422.19
更新日期:2003-09-30 00:00:00
abstract:BACKGROUND:Systemic administration of heparin can decrease mortality and morbidity of acute ischemic coronary syndromes such as unstable angina and myocardial infarction. Hemorrhage is the major limiting factor in the clinical use of systemic heparin. The objective of the present study was to determine whether local de...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.92.7.1697
更新日期:1995-10-01 00:00:00
abstract:BACKGROUND:Cardiac ischemia on the ambulatory ECG (AECG) and/or on the exercise treadmill test (ETT) is associated with an increased risk of adverse outcome. Myocardial revascularization more often suppresses cardiac ischemia than does medical management alone. However, few studies have compared the effects of percutan...
journal_title:Circulation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1161/01.cir.92.9.1
更新日期:1995-11-01 00:00:00
abstract:BACKGROUND:Vascular smooth muscle cell (VMSC) proliferation is an essential component of myointimal hyperplasia, which is implicated in the failure of 30% to 50% of vascular interventions, such as coronary angioplasty and peripheral vein grafting. We have shown that cells derived from stenotic lesions in infrainguinal ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.97.25.2506
更新日期:1998-06-30 00:00:00
abstract:BACKGROUND:Although global ischemia induces troponin I (TnI) degradation, regional ischemia does not. We hypothesized that this disparity is related to preload-induced proteolysis, which varies as a function of the amount of myocardium at risk of ischemia. METHODS AND RESULTS:Isolated rat hearts were buffer-perfused a...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.103.16.2035
更新日期:2001-04-24 00:00:00
abstract:BACKGROUND:Hypertrophic cardiomyopathy (HCM) is diagnosed clinically by the presence of left ventricular hypertrophy (LVH). However, LVH is absent in a significant number of genotype-positive patients. Because myocyte dysfunction and disarray are the primary abnormalities in HCM, we reasoned that tissue Doppler imaging...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.102.12.1346
更新日期:2000-09-19 00:00:00
abstract:BACKGROUND:Combining 2 signals of cardiomyocyte injury, cardiac troponin I (cTnI) and T (cTnT), might overcome some individual pathophysiological and analytical limitations and thereby increase diagnostic accuracy for acute myocardial infarction with a single blood draw. We aimed to evaluate the diagnostic performance ...
journal_title:Circulation
pub_type: 杂志文章,多中心研究
doi:10.1161/CIRCULATIONAHA.117.032003
更新日期:2018-09-04 00:00:00
abstract:BACKGROUND:Heterogeneous electrophysiological properties, which may be due in part to autonomic innervation, are important in the maintenance of atrial fibrillation (AF). We hypothesized that heterogeneous sympathetic denervation with phenol would create a milieu for sustained AF. METHODS AND RESULTS:After the determi...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.98.23.2608
更新日期:1998-12-08 00:00:00
abstract:BACKGROUND:Inhomogeneity of dose distribution and anatomic aspects of the atherosclerotic plaque may influence the outcome of irradiated lesions after balloon angioplasty (BA). We evaluated the influence of delivered dose and morphological characteristics of coronary stenoses treated with beta-radiation after BA. METH...
journal_title:Circulation
pub_type: 临床试验,杂志文章
doi:10.1161/01.cir.101.21.2472
更新日期:2000-05-30 00:00:00
abstract::Common conditions predisposing to atherosclerosis, such as hypercholesterolemia, hypertension, diabetes, and smoking, are associated with endothelial dysfunction. Endothelial function has largely been assessed as endothelium-dependent vasomotion, at least in part based on the assumption that impaired endothelium-depen...
journal_title:Circulation
pub_type: 杂志文章,评审
doi:10.1161/01.CIR.0000129501.88485.1f
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND:Unlike the Western world, valvular disease ranks among the major cardiovascular afflictions in Africa. Acute rheumatic fever and chronic rheumatic valvular disease in their most virulent form are still commonly encountered and impose a huge burden on limited healthcare resources. METHODS AND RESULTS:We perf...
journal_title:Circulation
pub_type: 杂志文章,评审
doi:10.1161/CIRCULATIONAHA.105.539775
更新日期:2005-12-06 00:00:00
abstract::Coronary artery bypass grafts, angioplasty, and thrombolysis are beneficial procedures for patients with coronary artery disease. However, these procedures can fail by mechanisms related to interactions between platelets and the damaged arterial wall. An experimental model for studying some of the mechanisms of platel...
journal_title:Circulation
pub_type: 杂志文章,评审
doi:
更新日期:1991-06-01 00:00:00
abstract:BACKGROUND:Epinephrine has been shown to impair pulmonary excretion of CO2 during resuscitation. This phenomenon was investigated in a rodent model of cardiac arrest and conventional resuscitation. METHODS AND RESULTS:The effects of racemic epinephrine were compared with the selective alpha 1-agonist methoxamine and w...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.84.5.2101
更新日期:1991-11-01 00:00:00
abstract::Three hundred consecutive patients who developed unstable postinfarction angina requiring isolated coronary artery bypass from 1982 through 1987 were analyzed. Hospital mortality was 5%; 15 (5.5%) additional late deaths occurred during the 69-month follow-up period (mean follow-up, 23.3 months). Significant independen...
journal_title:Circulation
pub_type: 杂志文章
doi:
更新日期:1989-06-01 00:00:00
abstract:BACKGROUND:Activated fibroblasts (myofibroblasts) play a critical role in cardiac fibrosis; however, their origin in the diseased heart remains unclear, warranting further investigation. Recent studies suggest the contribution of bone marrow fibroblast progenitor cells (BM-FPCs) in pressure overload-induced cardiac fib...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.117.027889
更新日期:2017-09-05 00:00:00