Synthesis of racemic 6,10,14-trimethylpentadecan-2-ol, a pheromone of rice moth and 5,9,13-trimethyltetradecanoic acid, a component of marine sponge from a common intermediate.

Abstract:

:A facile synthesis of dl-6,10,14-trimethylpentadecan-2-ol (1) a pheromone component of rice moth, Corcyra cephalonica Stainton and 5,9,13-trimethyltetradecanoic acid (2) a component of marine sponge, Cinachyrella alloclada Uliczka, using a common, intermediate, hexahydrofarnesol is accomplished. The salient features for 1 are: Grignard coupling of 5 with allylmagnesium bromide and oxymercuration-demercuration whereas for 2 they are: Knoevenagel condensation and subsequent hydrogenation.

journal_name

Bioorg Med Chem

authors

Rane SS,Chadha MS,Mamdapur VR

doi

10.1016/s0968-0896(00)82149-5

subject

Has Abstract

pub_date

1993-12-01 00:00:00

pages

399-401

issue

6

eissn

0968-0896

issn

1464-3391

pii

S0968-0896(00)82149-5

journal_volume

1

pub_type

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