Abstract:
BACKGROUND:A hypothesis of an increased risk for destructive periodontal diseases due to psychological stress has long been promoted. However, the research on stress and periodontal disease is still in its infancy. One of the reasons is thought to be that there is no suitable animal model for investigating the relationship. METHODS:One hundred male Wistar rats were included. A nylon ligature was placed around the second right maxillary molars. The animals were then divided into group S, exposed to a restraint stress for 12 hours/day for up to 10 days, and group N, controls. Ten animals were sacrificed on days 2, 4, 6, 8, and 10. Blood samples were taken, and the blood glucose level and the concentrations of adrenocorticotropic hormone, corticosterone, and adrenaline were measured as the markers of stress. The atrophies of the thymus and the spleen were measured. The furcation area of the second maxillary molars was examined histologically and histometrically. RESULTS:In group S, all values of stress markers were increased, and the thymus and the spleen were atrophied. Whereas group N showed only slight alveolar bone resorption, a marked alveolar bone resorption occurred in group S between days 8 and 10. An increase in beaded nerve terminals occurred around the vessels in the furcation area of group S. CONCLUSION:The results of the present study suggest that the restraint stress modulates the progression of periodontal inflammation and that this rat model is suitable for investigating the association between stress and periodontal disease.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Takada T,Yoshinari N,Sugiishi S,Kawase H,Yamane T,Noguchi Tdoi
10.1902/jop.2004.75.2.306subject
Has Abstractpub_date
2004-02-01 00:00:00pages
306-15issue
2eissn
0022-3492issn
1943-3670journal_volume
75pub_type
杂志文章abstract:BACKGROUND:The role played by the internal basal lamina (IBL) and hemidesmosomes between an implant and the peri-implant epithelium (PIE) in the adherence of the epithelium to the implant is controversial. This study used rat maxilla implantation models to clarify the ultrastructure of the PIE-implant interface. METHO...
journal_title:Journal of periodontology
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doi:10.1902/jop.2000.71.6.961
更新日期:2000-06-01 00:00:00
abstract::A retrospective study was conducted of 620 patients in a periodontal practice over the years 1960 to 1982. Various periodontal therapies were assessed by using careful office protocols, meticulous record-keeping and well-defined outcome criteria. Four treatment outcome categories were used: two representing satisfacto...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1985.56.5.253
更新日期:1985-05-01 00:00:00
abstract::In previous studies Fusobacterium nucleatum has been shown to induce either stimulatory or inhibitory effects on human mononuclear cells. We examined the interaction of human mononuclear cells with human and cynomolgus monkey strains of F. nucleatum. Peripheral blood mononuclear cells (PBMCs) isolated from normal dono...
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doi:10.1902/jop.2011.110088
更新日期:2012-02-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1981-07-01 00:00:00
abstract:BACKGROUND:Surface modifications to dental implants have been used in an attempt to accelerate the osseointegration process. The objective of this study was to biomechanically/histomorphometrically evaluate a bioceramic grit-blasted and acid-etched surface (BGB/AA; test) versus a dual acid-etched implant surface (contr...
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doi:10.1902/jop.2008.080106
更新日期:2008-10-01 00:00:00
abstract:BACKGROUND:Members of the matrix metalloproteinase (MMP) family are implicated in the chronic remodeling in periodontal diseases. Therefore, we performed a case-control study to investigate a plausible association between susceptibility to chronic periodontitis (CP) and the polymorphisms in the MMP-9 (gelatinase B) gen...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.050347
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:Cannabis sativa (marijuana) can interfere with bone physiopathology because of its effect on osteoblast and osteoclast activity. However, its impact on periodontal tissues is still controversial. The present study evaluates whether marijuana smoke affects bone loss (BL) on ligature-induced periodontitis in r...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2011.100362
更新日期:2011-11-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1985.56.6.330
更新日期:1985-06-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1995.66.12.1069
更新日期:1995-12-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2008.080066
更新日期:2008-10-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2013.1340020
更新日期:2013-04-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2008.070623
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:Purified recombinant human platelet-derived growth factor BB (rhPDGF-BB) is a potent wound healing growth factor and stimulator of the proliferation and recruitment of both periodontal ligament (PDL) and bone cells. The hypothesis tested in this study was that application of rhPDGF-BB incorporated in bone al...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2003.74.9.1282
更新日期:2003-09-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2012.110472
更新日期:2012-10-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1995.66.10.870
更新日期:1995-10-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2000.71.4.568
更新日期:2000-04-01 00:00:00
abstract::Invasion of gingival tissues by bacteria is thought to be a major factor in development of periodontal lesions. Morphologic studies have revealed bacteria within the pocket epithelium, gingival connective tissues, alveolar bone, and oral epithelium. The current studies are intended to determine whether they are presen...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1990.61.1.35
更新日期:1990-01-01 00:00:00
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pub_type: 杂志文章,meta分析,评审
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更新日期:2011-08-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
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更新日期:1990-07-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2014-12-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
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更新日期:1988-02-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2017.170025
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:This study compares the levels of cytokines and bone-related factors in the gingival crevicular fluid (GCF) of systemically healthy patients with chronic periodontitis (CP); and better-controlled, and poorly controlled patients with type 2 diabetes and CP. METHODS:Thirty-seven patients with type 2 diabetes ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2011.100643
更新日期:2011-08-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
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更新日期:2013-07-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
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更新日期:2013-05-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.1993.64.5s.474
更新日期:1993-05-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1999.70.12.1457
更新日期:1999-12-01 00:00:00
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journal_title:Journal of periodontology
pub_type: 杂志文章
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更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:One of the success factors in periodontal plastic surgery is the synergistic relationship between involved tissues and vascular supply. Gingiva as a functional unit is unique with a specific vascular configuration and contains the supracrestal portion naturally created to survive over avascular root surfaces...
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pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2012.110685
更新日期:2013-01-01 00:00:00