Abstract：
INTRODUCTION:Dementia is more frequent in patients suffering from Parkinson's disease (PD) then in general population. The mechanism for mental deterioration in PD remains controversial. The aim of our study was comparison of the regional cerebral perfusion quantified by single photon emission computed tomography in patients suffering from idiopathic Parkinson's disease with and without dementia. MATERIAL AND METHODS:We examined 49 PD patients: 22 PD patients with dementia and 27 PD patients without dementia. Dementia was recognized according to ICD-10 and DSM-IV criteria. Cognitive functions were executed by means of the Mini Mental State Examination (MMSE) and neuropsychological assessment. The Unified Parkinson's Disease Rating Scale (UPDRS) and Modified Hoehn & Yahr Scale was used to quantify the severity of PD. SPECT was performed with Siemens Diacam single--head rotating gamma camera after intravenous application of technetium 99m hexamethylpropylene amine oxime (99mTc-HMPAO). The perfusion values were expressed as cortical or basal ganglia regions of interest (ROIs)/cerebellum activity ratios. RESULTS:In both examined group of patients the lowest uptake was in basal ganglia region, while the highest uptake was in occipital region. In the subgroup of PD patients with dementia significant hypoperfusion affecting the inferior frontal cortices was observed. CONCLUSIONS:In Parkinson's disease with dementia hypoperfusion in inferior frontal region can be found.
journal_name
Neurol Neurochir Poljournal_title
Neurologia i neurochirurgia polskaauthors
Ochudło S,Opala G,Jasińska-Myga B,Siuda J,Nowak Ssubject
Has Abstractpub_date
2003-01-01 00:00:00pages
133-44eissn
0028-3843issn
1897-4260journal_volume
37 Suppl 5pub_type
杂志文章abstract：:Deep brain stimulation (DBS) is a neurosurgical treatment of Parkinson's disease and other movement disorders. This surgical technique is applied to three brain targets: the ventral intermediate nucleus of the thalamus (Vim), the globus pallidus internus (Gpi) and the subthalamic nucleus (STN). Vim DBS improves contra...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：2006-05-01 00:00:00
abstract：:The authors discuss the etiology and pathogenesis of SSPE in the light of own observations of two boys aged 8 and 9 years whose one grandfather and one grandmother were siblings. The boys lived in different parts of Poland and never been in contact with each other. In the light of this observation the authors discuss ...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1983-11-01 00:00:00
abstract：:On the basis of experimental investigations the authors describe the causes of certain complications after extracorporeal circulation. The experiments were carried out in 11 sheep. The duration of extracorporeal circulation was from 1 to 2 hours. It was found that the intracranial pressure, which is an indicator of in...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1986-07-01 00:00:00
abstract：:Slowly progressive neuromuscular diseases include but are not limited to: facioscapulohumeral muscular dystrophy (FSHD) and limb-girdle muscular dystrophy (LGMD), hereditary motor and sensory neuropathy (HMSN) and spinal muscular atrophy type III (SMA3). The purpose of this study is to present an evaluation of basic a...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1995-07-01 00:00:00
abstract：:On the basis of personal investigations including 1) electrophysiological methods (EEG, averaged evoked potentials), 2) behavior methods, 3) destruction of various parts of the brain (mesencephalic reticular formation, auditory pathways) and 4) pharmacological methods, conducted in the years 1953-1974 the author put f...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1976-07-01 00:00:00
abstract：:Multiple sclerosis (MS) should be differentiated with diseases causing disseminated lesions of central nervous system or imitating clinical course of MS. Clinical course and results of laboratory investigations also immunological tests should be taken into account in differential diagnosis of MS. We present four patie...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：2001-01-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：10.5603/PJNNS.a2019.0023
更新日期：2019-01-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.pjnns.2014.05.005
更新日期：2014-01-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2017.04.001
更新日期：2018-01-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2017.05.005
更新日期：2017-01-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：2001-03-01 00:00:00
abstract：:From a group of 248 cases of epilepsy observed in the last five years 69 (28%) children, 32 boys and 37 girls, were isolated (aged from several months to 14 years) in whom the first epileptic seizures appeared at the age of 3 years or less. The subgroups were subjected to detailed psychiatric-psychological analysis fo...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1984-11-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:Involuntary movements are rare ischemic stroke complication. Hemichorea, hemibalism and dystonia cases were described, especially during haemorrhage into basal ganglia and thalamus. The case of 73 years old woman is presented who was admitted to our Clinic cause of sudden choreatic involuntary movements occurrence wit...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：10.1016/j.pjnns.2016.10.003
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journal_title：Neurologia i neurochirurgia polska
pub_type： 临床试验,杂志文章,多中心研究
doi：
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2004-07-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
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doi：10.1016/j.pjnns.2018.09.007
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
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更新日期：2001-01-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章,评审
doi：
更新日期：1992-01-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Parkinson disease (PD) is a risk factor for dementia. In addition, specific cognitive deficits can occur in PD patients without dementia. A patient's level of education could have an influence on the development of cognitive impairment in PD. The aim of this study was to examine the relationship ...
journal_title：Neurologia i neurochirurgia polska
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doi：10.1016/s0028-3843(14)60056-6
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
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journal_title：Neurologia i neurochirurgia polska
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doi：
更新日期：1979-03-01 00:00:00
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journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
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abstract：:The authors describe a case of spinal intracanal cysticercosis. The cysts were situated intradurally, provoking radicular symptoms: pain, paresis. CT investigations showed herniation of discs L4/L5 and L5/S1 interpreted as the cause of the mentioned symptoms. Surgical treatment included discectomy L4/L5 and L5/S1. Rec...
journal_title：Neurologia i neurochirurgia polska
pub_type： 杂志文章
doi：
更新日期：2000-07-01 00:00:00
