Advances in understanding the mechanisms and management of acute myelogenous leukemia.

Abstract:

PURPOSE/OBJECTIVES:To review current knowledge about the causes, pathophysiology, treatment, and nursing care of patients with acute myelogenous leukemia (AML). DATA SOURCES:Articles, books, and proceedings of national meetings. DATA SYNTHESIS:AML, an an often fatal disease, is characterized by signs of anemia, thrombocytopenia, neutropenia, and leukemic cell infiltration throughout the body. Possible etiologies include genetic predisposition and exposure to radiation, chemicals, and viruses. Various types of chemotherapy and bone marrow transplantation are treatments of choice. Both result in significant side effects and complication rates. CONCLUSIONS:Throughout every stage, nursing care is of the utmost importance. Research continues to increase understanding of the disease process and the survival of patients. IMPLICATIONS FOR NURSING PRACTICE:Goals of care are directed at prevention of bleeding, infection, fluid and electrolyte imbalance, and chemotherapy-related side effects; assisting patients and families to cope with diagnoses, therapy, and prognoses; and helping the patient to achieve an acceptable quality of life regardless of the eventual outcome.

journal_name

Oncol Nurs Forum

journal_title

Oncology nursing forum

authors

Yeager KA,Miaskowski C

subject

Has Abstract

pub_date

1994-04-01 00:00:00

pages

541-8

issue

3

eissn

0190-535X

issn

1538-0688

journal_volume

21

pub_type

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