The standard of care debate: can research in developing countries be both ethical and responsive to those countries' health needs?

Abstract:

:To avoid exploitation of host communities, many commentators argue that subjects must receive the best methods available worldwide. Others worry that this requirement may block important research intended to improve health care, especially in developing countries. To resolve this dilemma, we propose a framework for the conditions under which it is acceptable to provide subjects with less than the best methods. Specifically, institutional review boards should assume a default of requiring the "worldwide best" methods, meaning the best methods available anywhere in the world, in all cases.However, institutional review boards should be willing to grant exceptions to this default for research studies that satisfy the following 4 conditions: (1) scientific necessity, (2) relevance for the host community, (3) sufficient host community benefit, and (4) subject and host community non-maleficence.

journal_name

Am J Public Health

authors

Wendler D,Emanuel EJ,Lie RK

doi

10.2105/ajph.94.6.923

subject

Has Abstract

pub_date

2004-06-01 00:00:00

pages

923-8

issue

6

eissn

0090-0036

issn

1541-0048

pii

94/6/923

journal_volume

94

pub_type

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