Prognostic value of inducible myocardial ischemia in predicting cardiovascular events after renal transplantation.

abstract：:A genome-wide association scan of the Genetics of Kidneys in Diabetes (GoKinD) collections identified four novel susceptibility loci, located on chromosomes 7p14.3, 9q21.32, 11p15.4, and 13q33.3 associated with type 1 diabetic nephropathy. A recent evaluation of these loci in Japanese patients with type 2 diabetes sup...

journal_title：Kidney international

authors： Pezzolesi MG,Poznik GD,Skupien J,Smiles AM,Mychaleckyj JC,Rich SS,Warram JH,Krolewski AS

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:The feasibility of simultaneously infusing glucose and amino acid (AA)-based peritoneal dialysis solutions was tested to determine whether peritoneal dialysis patients could achieve an adequate nonprotein calorie/nitrogen ratio while preventing a marked increase in blood urea nitrogen (BUN), which is usually...

journal_title：Kidney international

authors： Canepa A,Carrea A,Menoni S,Verrina E,Trivelli A,Gusmano R,Perfumo F

更新日期：2001-05-01 00:00:00

abstract：:Tubulointerstitial nephritis (TIN) is a disease pattern with heterogeneous causes. Recently a specific subtype of autoimmune TIN, IgG4-related TIN, has been identified that is part of systemic IgG4-related disease/ autoimmune pancreatitis. On biopsy, this TIN shows an IgG4+ plasma cell-rich infiltrate, akin to the pan...

journal_title：Kidney international

authors： Cornell LD

更新日期：2010-11-01 00:00:00

abstract：:Spontaneous and aspirated blood samples were collected from the welling points of surface efferent arterioles in the rat kidney. The amount of tubular reabsorbate in each sample was calculated from measurements of the inulin concentration in the sample and systemic arterial plasma. Both spontaneous and aspirated sampl...

journal_title：Kidney international

authors： Jensen PK,Blaehr H,Steven K

更新日期：1984-03-01 00:00:00

abstract：:A high frequency (25%) of anti-hepatitis C virus (HCV) antibodies is observed in French hemodialyzed patients; this is associated with detectable viremia in 85% and results in chronic hepatitis in more than 90%. We conducted a pilot study to examine the tolerance and efficacy of alpha-2b Interferon therapy upon HCV in...

journal_title：Kidney international

authors： Pol S,Thiers V,Carnot F,Zins B,Romeo R,Berthelot P,Bréchot C

更新日期：1995-05-01 00:00:00

abstract：:Many transgenic and knockout mice with increased urine flow have structural abnormalities of the renal pelvis and inner medulla. Here, we used high resolution contrast enhanced T1-weighted magnetic resonance imaging of mice whose urea transporters UT-A1 and UT-A3 were deleted (UT-A1/3(-/-) mice) as a model for the in ...

journal_title：Kidney international

authors： Jacob VA,Harbaugh CM,Dietz JR,Fenton RA,Kim SM,Castrop H,Schnermann J,Knepper MA,Chou CL,Anderson SA

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Familial nephrotic syndrome (NS) has both autosomal dominant and recessive forms of inheritance. Recent studies in families with an autosomal dominant form of focal segmental glomerulosclerosis (FSGS) have been at odds concerning linkage to chromosome 19q13 (Mathis et al, Kidney Int 53:282-286, 1998; Winn et...

journal_title：Kidney international

authors： Vats A,Nayak A,Ellis D,Randhawa PS,Finegold DN,Levinson KL,Ferrell RE

更新日期：2000-03-01 00:00:00

abstract：:Previous studies have shown a number of different associations between major histocompatibility complex (MHC) alleles and primary systemic vasculitis. Disease heterogeneity and the lack of specificity of certain MHC typing techniques may have contributed to the lack of consistency in those studies. We therefore studie...

journal_title：Kidney international

authors： Zhang L,Jayne DR,Zhao MH,Lockwood CM,Oliveira DB

更新日期：1995-01-01 00:00:00

abstract：:Although case reports link proton-pump inhibitor (PPI) use and hypomagnesemia, no large-scale studies have been conducted. Here we examined the serum magnesium concentration and the likelihood of hypomagnesemia (<1.6 mg/dl) with a history of PPI or histamine-2 receptor antagonist used to reduce gastric acid, or use of...

journal_title：Kidney international

authors： Danziger J,William JH,Scott DJ,Lee J,Lehman LW,Mark RG,Howell MD,Celi LA,Mukamal KJ

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:An Experimental model of proliferative glomerulonephritis induced by an antibody against Thy-1 antigen has been established. However, the pathophysiologic role and the critical epitope of Thy-1 molecule for induction of mesangial cell dysfunction remain unknown. We have reported that monoclonal antibody 1-22...

journal_title：Kidney international

authors： Morioka T,Yao J,Suzuki Y,Oite T

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Aldosterone has been suggested to play a role in the initiation and progression of diabetic nephropathy. Currently recommended treatment with angiotensin-converting enzyme (ACE) inhibitors or angiotensin II receptor blockers [renin-angiotensin system (RAS) blockade] does not suppress circulating aldosterone ...

journal_title：Kidney international

authors： Schjoedt KJ,Rossing K,Juhl TR,Boomsma F,Rossing P,Tarnow L,Parving HH

更新日期：2005-12-01 00:00:00

abstract：:To assess in vitro erythropoietic cultures as a tool to discriminate between patients whose anemia improves with and those whose anemia fails to improve with androgens, bone marrows of 24 anemic patients receiving maintenance hemodialysis in hormone-depleted plasma clots were cultured. While erythroid colony prolifera...

journal_title：Kidney international

authors： Kalmanti M,Dainiak N,Martino J,Dewey M,Kulkarni V,Howard D

更新日期：1982-10-01 00:00:00

abstract：BACKGROUND:Studies in animal models have shown that the alternative pathway of complement is activated in the kidney after ischemia/reperfusion. In addition, mice deficient in complement factor B, a necessary component of the alternative pathway, are protected from ischemic acute renal failure. The purpose of this stud...

journal_title：Kidney international

authors： Thurman JM,Lucia MS,Ljubanovic D,Holers VM

更新日期：2005-02-01 00:00:00

abstract：:Tremendous progress has been made over recent years in the understanding of the mechanisms regulating calcium, phosphorus, vitamin D, and parathyroid hormone homeostasis in the normal human body and in patients with different degrees of renal failure. In addition, some of these findings have been translated into clini...

journal_title：Kidney international

authors： De Broe ME

更新日期：2009-05-01 00:00:00

abstract：:The acute renal effects of hypoxemia and the ability of theophylline to prevent these effects were assessed in anesthetized and mechanically-ventilated newborn and adult rabbits. Renal blood flow (RBF) and glomerular filtration rate (GFR) were determined by the clearance of para-aminohippuric acid and inulin, respecti...

journal_title：Kidney international

authors： Gouyon JB,Guignard JP

更新日期：1988-06-01 00:00:00

abstract：:Renal dysfunction is a common and serious complication in multiple myeloma (MM) patients. Renal proximal tubule injury is characteristic in MM, and may result in disturbed renal handling of various vitamins. The abnormal excretion of vitamins in urine may result in their low serum levels. The goal of this study was to...

journal_title：Kidney international

authors： Gavrilov V,Yermiahu T,Gorodischer R

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:The pathophysiology of hypertension in patients with chronic kidney disease (CKD) is largely attributed to positive sodium balance. It is unclear how loop diuretics affect fluid volume compartments, especially with respect to their antihypertensive effect. METHODS:Subjects with CKD were administered a singl...

journal_title：Kidney international

authors： Vasavada N,Agarwal R

更新日期：2003-11-01 00:00:00

abstract：:In six healthy males on a fixed sodium/potassium (Na/K) intake, we studied the relation between plasma K and urine K and Na excretion after an oral K load. Studies were repeated during fludrocortisone (0.5 mg bid) or spironolactone (50 mg qid), that is, after escape from the Na-retaining and Na-excreting effects of th...

journal_title：Kidney international

authors： Hené RJ,Koomans HA,Rabelink AJ,Boer P,Dorhout Mees EJ

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Alterations of large artery function and structure are frequently observed in renal allograft recipients. However, endothelial function has not yet been assessed in this population. METHODS:Flow-mediated vasodilation is a useful index of endothelial function. We measured the diameter and distensibility of t...

journal_title：Kidney international

authors： Hausberg M,Kisters K,Kosch M,Rahn KH,Barenbrock M

更新日期：1999-03-01 00:00:00

abstract：:Proliferation of mesangial cells is frequently found in glomerulonephritis, such as IgA glomerulonephritis. Recent reports suggest that a brain/embryo-type myosin isoform (MIIB2) is involved in cell proliferation. We have studied the expression of MIIB2 in renal biopsy samples from patients with various renal diseases...

journal_title：Kidney international

authors： Kishino M,Kimura A,Yamaguchi K,Ohtani H,Yamada Y,Takahashi T,Mune M,Mimura K,Maeda T,Matsumura S,Tsuji T,Yukawa S

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:The superiority of renin-angiotensin system (RAS) blockade in providing renoprotection has been attributed to class-specific blood pressure "(BP)-independent" mechanisms. However, the conventional BP measurement methodology on which such conclusions are based is inherently limited for an accurate assessment ...

journal_title：Kidney international

authors： Bidani AK,Griffin KA,Bakris G,Picken MM

更新日期：2000-04-01 00:00:00

abstract：:The hypercalcemia of malignancy is mediated by complex and heterogeneous mechanisms. Once thought of as a simple paraneoplastic syndrome mediated by the effects of tumor production of PTH, it is now clear that multiple mechanisms are involved and that these mechanisms involve abnormalities in calcium transport in bone...

journal_title：Kidney international

authors： Mundy GR

更新日期：1987-01-01 00:00:00

abstract：:Using a combination of intra-operative digital photography and micro-biopsy we measured renal cortical and papillary changes in five patients with primary hyperparathyroidism and abundant calcium phosphate kidney stones. Major tissue changes were variable papillary flattening and retraction, dilation of the ducts of B...

journal_title：Kidney international

authors： Evan AE,Lingeman JE,Coe FL,Miller NL,Bledsoe SB,Sommer AJ,Williams JC,Shao Y,Worcester EM

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor (VEGF) and its receptors have been implicated in the pathogenesis of diabetic nephropathy. The objective of this study was to determine whether alterations of the plasma and urinary VEGF and sFLT-1 levels were related to the stages and risk factors of diabetic nephropathy. ...

journal_title：Kidney international

authors： Kim NH,Oh JH,Seo JA,Lee KW,Kim SG,Choi KM,Baik SH,Choi DS,Kang YS,Han SY,Han KH,Ji YH,Cha DR

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:The new oral microemulsion formulation of cyclosporine (Neoral) possesses superior pharmacokinetics to the conventional formulation, Sandimmun (SIM), providing more complete and predictable absorption, and less pharmacokinetic variability. METHODS:The safety and tolerability of Neoral, together with the inc...

journal_title：Kidney international

authors： Keown P,Niese D

更新日期：1998-09-01 00:00:00

abstract：:The present studies address the metabolic processes that support the reabsorption of sodium and the secretion of bicarbonate in the interspersed but distinct principal and intercalated cells of the cortical collecting duct (CCD). In microperfused rabbit CCD, sodium reabsorption was measured by lumen-to-bath 22Na flux,...

journal_title：Kidney international

authors： Hering-Smith KS,Hamm LL

更新日期：1998-02-01 00:00:00

abstract：:Nephronophthisis is an autosomal recessive kidney disease with high genetic heterogeneity. Understanding the functions of the individual genes contributing to this disease is critical for delineating the pathomechanisms of this disorder. Here, we investigated kidney function of a novel gene associated with nephronopht...

journal_title：Kidney international

authors： Airik R,Airik M,Schueler M,Bates CM,Hildebrandt F

更新日期：2019-08-01 00:00:00

abstract：:The presence of CR1 mRNA in podocytes was investigated using a 35S-labeled CR1 cDNA probe and in situ hybridization in sections from fetal and adult human kidneys. CR1 mRNA was only detected in immature podocytes at early stages of glomerular differentiation in the fetal kidney. In contrast, CR1 antigen was abundantly...

journal_title：Kidney international

authors： Appay MD,Kazatchkine MD,Levi-Strauss M,Hinglais N,Bariety J

更新日期：1990-08-01 00:00:00

abstract：:Insulin resistance has been associated with kidney disease even in the absence of diabetes; however, pathways linking insulin resistance to kidney disease are unclear. The purpose of this study was to determine if transforming growth factor (TGF)-beta1, a key cytokine associated with kidney disease, responds to circul...

journal_title：Kidney international

authors： Huan Y,DeLoach S,Daskalakis C,Dunn SR,Sharma K,Falkner B

更新日期：2010-08-01 00:00:00

abstract：:Steroid Resistant Nephrotic Syndrome (SRNS) in children and young adults has differing etiologies with monogenic disease accounting for 2.9-30% in selected series. Using whole exome sequencing we sought to stratify a national population of children with SRNS into monogenic and non-monogenic forms, and further define t...

journal_title：Kidney international

authors： Bierzynska A,McCarthy HJ,Soderquest K,Sen ES,Colby E,Ding WY,Nabhan MM,Kerecuk L,Hegde S,Hughes D,Marks S,Feather S,Jones C,Webb NJ,Ognjanovic M,Christian M,Gilbert RD,Sinha MD,Lord GM,Simpson M,Koziell AB,Welsh

更新日期：2017-04-01 00:00:00