Severe ulcerative colitis: prospective study of parameters determining outcome.

abstract：BACKGROUND AND AIM:Controversy continues as to whether nutcracker esophagus (NE) is a 'real' manometric disease due to its poor correlation with clinical symptoms such as chest pain or dysphagia. While new NE criteria were proposed in a recent study, that study included NE patients both with and without gastroesophagea...

journal_title：Journal of gastroenterology and hepatology

authors： Jung KW,Jung HY,Yoon IJ,Kim DH,Chung JW,Oh HC,Choi KS,Choi KD,Song HJ,Lee GH,Kim JH

更新日期：2010-07-01 00:00:00

abstract：:Four types of materials, type I collagen coat (Coat), acid-soluble type I collagen gel (Hardgel), pepsin-treated acid-soluble type I collagen gel (Softgel), and an extract of extracellular matrix of the murine Engelbreth-Holm-Swarm sarcoma (Matrigel), were used as matrices to culture rat hepatic parenchymal cells, and...

journal_title：Journal of gastroenterology and hepatology

authors： Awata R,Sawai H,Imai K,Terada K,Senoo H,Sugiyama T

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND AND AIM:In mice and humans, the gastric epithelial progenitors undergo proliferation and bipolar migration from the isthmus associated with their differentiation into mucus-, acid- and pepsinogen-secreting cell lineages. Little is known about factors that control the dynamics of these isthmal progenitor cell...

journal_title：Journal of gastroenterology and hepatology

authors： Karam SM,Hassan WM,John R

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND AND AIM:To investigate the relationship between human leptin receptor (LEPR) gene G3057A polymorphism and type 2 diabetes mellitus (T2DM) patients complicated with or without non-alcoholic fatty liver disease (NAFLD). METHODS:Two hundred and sixteen cases of newly diagnosed T2DM patients (104 cases complica...

journal_title：Journal of gastroenterology and hepatology

authors： Lu H,Sun J,Sun L,Shu X,Xu Y,Xie D

更新日期：2009-02-01 00:00:00

abstract：:Alcoholic liver diseases (ALD) are frequently associated with iron overload. Until recently, the effects of ethanol in hepatic iron uptake and intestinal iron absorption have not been clarified in detail. Two possible mechanisms for iron overload are the uptake of iron into hepatocytes in a specific manner through the...

journal_title：Journal of gastroenterology and hepatology

authors： Kohgo Y,Ohtake T,Ikuta K,Suzuki Y,Torimoto Y,Kato J

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND AND AIM:In high or moderate risk populations, periodic surveillance of patients at risk of progression from gastric precursor lesions (PL) to gastric cancer (GC) is the most effective strategy for reducing the burden of GC. Incomplete type of intestinal metaplasia (IIM) may be considered as the best candidat...

journal_title：Journal of gastroenterology and hepatology

authors： González CA,Sanz-Anquela JM,Companioni O,Bonet C,Berdasco M,López C,Mendoza J,Martín-Arranz MD,Rey E,Poves E,Espinosa L,Barrio J,Torres MÁ,Cuatrecasas M,Elizalde I,Bujanda L,Garmendia M,Ferrández Á,Muñoz G,Andreu V

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND AND AIM:Liver stiffness (LS), measured by transient elastography, has been validated as a non-invasive surrogate for liver fibrosis. METHODS:We investigated the long-term predictive ability of LS for hepatocellular carcinoma (HCC) development and overall survival in 1146 patients with chronic hepatitis C by...

journal_title：Journal of gastroenterology and hepatology

authors： Nakagomi R,Tateishi R,Masuzaki R,Soroida Y,Iwai T,Kondo M,Fujiwara N,Sato M,Minami T,Uchino K,Enooku K,Nakagawa H,Asaoka Y,Kondo Y,Tanaka Y,Otsuka M,Kato N,Moriya K,Ikeda H,Koike K

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND AIM:Serum cancer antigen (CA) 125 elevation has been reported in patients with liver disease, but it is poorly characterized. The present study aimed to evaluate the range of serum and ascitic CA 125 levels in patients with liver cirrhosis and to explore possible factors associated with CA 125 elevation....

journal_title：Journal of gastroenterology and hepatology

authors： Xiao WB,Liu YL

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Significant changes in hepatic haemodynamics occur after major hepatectomy, but the pathogenesis of this phenomenon is unclear. This study investigates the serum profile of prostaglandin and nitric oxide in the hepatic and systemic circulation before and after hepatectomy and the temporal relationsh...

journal_title：Journal of gastroenterology and hepatology

authors： Lai OF,Chow PK,Tan S,Song IC,Soo KC,Aw SE,Yu WK,Fook-Chong SM,Satchithanantham S,Chan ST

更新日期：2000-08-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the most commonly diagnosed malignancy of the liver and is the third most frequent cause of cancer death worldwide. Although advances in HCC detection and treatment have increased the likelihood of a cure at early stages of the disease, HCC remains largely incurable because of late pr...

journal_title：Journal of gastroenterology and hepatology

authors： Tong CM,Ma S,Guan XY

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND AND AIM:Studies have shown monounsaturated oleic acid to be less toxic than palmitic acid and to prevent/attenuate palmitic acid hepatocites toxicity in steatosis models in vitro. However, to what degree these effects are mediated by steatosis extent is unknown. METHODS:We evaluated whether steatosis per se...

journal_title：Journal of gastroenterology and hepatology

authors： Ricchi M,Odoardi MR,Carulli L,Anzivino C,Ballestri S,Pinetti A,Fantoni LI,Marra F,Bertolotti M,Banni S,Lonardo A,Carulli N,Loria P

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND AND AIM:Liver transplantation remains the best option for treating type-1 hepatorenal syndrome (HRS1). The aim of this retrospective study was to determine whether the molecular adsorbent recirculation system (MARS) can improve renal function in HRS1 patients. METHODS:Thirty-two patients with chronic liver ...

journal_title：Journal of gastroenterology and hepatology

authors： Lavayssière L,Kallab S,Cardeau-Desangles I,Nogier MB,Cointault O,Barange K,Muscari F,Rostaing L,Kamar N

更新日期：2013-06-01 00:00:00

abstract：:Here we identify a previously unreported cause of rectal bleeding (juvenile polyposis) in a patient with cystic fibrosis (CF). We believe this patient most likely has two coexisting genetic diseases. It also raises many issues about organ transplantation in a patient with medical conditions that individually increase ...

journal_title：Journal of gastroenterology and hepatology

authors： Treepongkaruna S,Hardikar W,Chow CW,Smith AL,Oliver MR

更新日期：1999-03-01 00:00:00

abstract：:The Steering Committee for the Prevention and Control of Infectious Diseases in Asia recently conducted a survey of primary-care physicians in Asia, which revealed that many physicians administer boosters in their clinical practice and that there is considerable variation and uncertainty among physicians regarding thi...

journal_title：Journal of gastroenterology and hepatology

authors： John TJ,Cooksley G,Steering Committee for the Prevention and Control of Infectious Diseases in Asia.

更新日期：2005-01-01 00:00:00

abstract：:Since receptor-binding cancer antigen expressed on SiSo cells (RCAS1) was first reported as a tumor-associated antigen of gynecologic cancer, its function and practical value as a tumor marker have been investigated in various types of carcinomas. Basic research has indicated that RCAS1 expression in cancer cells cont...

journal_title：Journal of gastroenterology and hepatology

authors： Enjoji M,Nakashima M,Yamaguchi K,Kotoh K,Nakamuta M

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Oxidative stress plays an important role in the pathogenesis of chronic liver diseases. The plasma level of 8-isoprostane, a product of lipid peroxidation, is a marker of oxidative stress in vivo. The aim of the present study was to clarify whether the degree of lipid peroxidation, as measured by the plasma ...

journal_title：Journal of gastroenterology and hepatology

authors： Konishi M,Iwasa M,Araki J,Kobayashi Y,Katsuki A,Sumida Y,Nakagawa N,Kojima Y,Watanabe S,Adachi Y,Kaito M

更新日期：2006-12-01 00:00:00

abstract：:In order to achieve possible greater therapeutic efficacy, ranitidine 300 mg bid (R2) may be given rather than 300 mg qhs (R1), or nizatidine 300 mg bid (N2) may be given rather than 300 mg qhs (N1). A randomized placebo-controlled crossover study was performed in six healthy volunteers (four males, two females) who r...

journal_title：Journal of gastroenterology and hepatology

authors： Thompson A,Kirdeikis P,Jamali F,Tavernini M,Zuk L,Marriage B,Simpson I,Mahachai V

更新日期：1995-09-01 00:00:00

abstract：:It was recently reported that mutations in the precore and core promoter region of hepatitis B virus (HBV) are associated with fulminant hepatitis. The aim of this study was to investigate the association of mutations in the precore and core promoter region of HBV with fulminant and severe acute hepatitis. We studied ...

journal_title：Journal of gastroenterology and hepatology

authors： Aritomi T,Yatsuhashi H,Fujino T,Yamasaki K,Inoue O,Koga M,Kato Y,Yano M

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND AND AIM:Cholangiocarcinoma (CCA) is a mucin-producing cancer that has poor prognosis. Mucin 6 (MUC6) is a mucin that is normally co-expressed with the trefoil factor family-2 (TFF2) trefoil peptide. Both MUC6 and TFF2 have been reported to be involved in the progression of many types of cancers. The aim of t...

journal_title：Journal of gastroenterology and hepatology

authors： Thuwajit P,Chawengrattanachot W,Thuwajit C,Sripa B,Paupairoj A,Chau-In S

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Anti-neutrophil cytoplasmic antibodies (ANCA) against proteinase 3 are diagnostic of Wegener's granulomatosis, but ANCA occur also in patients with other inflammatory disorders, such as ulcerative colitis, primary sclerosing cholangitis (PSC) and autoimmune hepatitis. As their predictive value for autoimmune...

journal_title：Journal of gastroenterology and hepatology

authors： Lindgren S,Nilsson S,Nässberger L,Verbaan H,Wieslander J

更新日期：2000-04-01 00:00:00

abstract：INTRODUCTION:The aim of the present study was to determine whether rats with moderately fatty liver could withstand a 90% hepatectomy, which rats with normal livers can survive. MATERIAL AND METHODS:Nine-week-old male Wistar rats were used. Normal rat chow was fed to the normal liver group, and fat-enriched rat chow w...

journal_title：Journal of gastroenterology and hepatology

authors： Morioka D,Watanabe K,Makino H,Saito S,Ueda M,Kubota T,Sekido H,Matsuo K,Ichikawa Y,Endo I,Togo S,Shimada H

更新日期：2006-02-01 00:00:00

abstract：AIM:To investigate the factors affecting the outcome of fulminant hepatic failure (FHF) in children in relation to hepatitis B virus (HBV) infection. METHODS:Retrospective review of a total of 94 cases (61 males and 33 females, aged from 1 month to 15 years) recruited from nine tertiary referral centers in Taiwan from...

journal_title：Journal of gastroenterology and hepatology

authors： Chan PC,Chen HL,Kong MS,Huang FC,Lee HC,Lin CC,Liu CC,Lee IH,Wu TC,Wu SF,Ni YH,Hsu HY,Chang MH

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND AND AIM:Early life exposure to the famine may affect the susceptibility to the metabolic disorders. The objective of this study was to examine the associations of early life exposure to the Chinese Famine (1959-1961) with the risk of fatty liver disease, obesity, hypertension, and hyperglycemia in adulthood....

journal_title：Journal of gastroenterology and hepatology

authors： Chen JP,Peng B,Tang L,Sun R,Hu S,Wen XY,Que P,Wang YH

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Absolute lymphocyte count (ALC) and the recovery of ALC after treatment have been identified as a prognostic biomarker for several malignancies. In this study, we aimed to investigate the prognostic role of peritransplant ALC and ALC recovery after liver transplantation (LT) in hepatocellular carcin...

journal_title：Journal of gastroenterology and hepatology

authors： Zheng Z,Lin B,Zhang J,Yang Z,Xie H,Zhou L,Zhang M,Zheng S

更新日期：2015-04-01 00:00:00

abstract：:Gastric cancer usually shows poor sensitivity to chemotherapy, and the presence of lymph node metastases is associated with extremely poor prognosis, especially when the number of such nodes is more than 10. We report here a case of advanced gastric cancer with histopathologically confirmed metastases in 15 regional l...

journal_title：Journal of gastroenterology and hepatology

authors： Shigemitsu K,Naomoto Y,Matsuno T,Gochi A,Isozaki H,Tanaka N

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND AND AIM:Survivin has functions in both the regulation of cell division and the inhibition of apoptosis, and it is expressed in most human tumors but not in normal adult tissues. It is a potential target for cancer gene therapy. In the present study, we designed a DNAzyme targeting human survivin mRNA and tri...

journal_title：Journal of gastroenterology and hepatology

authors： Liang Z,Wei S,Guan J,Luo Y,Gao J,Zhu H,Wu S,Liu T

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND AND AIM:Glypican-3 (GPC3) expression is correlated with poor prognosis and progression in hepatocellular carcinoma (HCC). HCC progression can be associated with the differentiation status of tumor cell before malignant transformation. Our aim was to investigate the dynamic expression of GPC3 during tumor cel...

journal_title：Journal of gastroenterology and hepatology

authors： Xue R,Feng J,Meng Q,Lv F,Zhu Y,Yu H,Zhang S,Song C,Sun L,Yue Z,Feng S,Che R,Xiang Q,Jing X

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:The pathophysiology of constipation is not clearly identified as yet, and the interstital cells of Cajal (ICC), known to generate the slow wave activity and to be involved in intestinal neurotransmission and the enteric nervous system (ENS), are suspected to play an important role. The aims of the present st...

journal_title：Journal of gastroenterology and hepatology

authors： Lee JI,Park H,Kamm MA,Talbot IC

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND AND AIM:Although rabeprazole (RPZ), a proton pump inhibitor, has been reported to have a bactericidal effect on Helicobacter pylori (H. pylori), no studies have been conducted regarding the effect of RPZ on gastric mucosal lesion formation caused by this bacterium. In the present study, we investigated the e...

journal_title：Journal of gastroenterology and hepatology

authors： Suzuki H,Miyazawa M,Nagahashi S,Sato M,Bessho M,Nagata H,Miura S,Ishii H

更新日期：2003-07-01 00:00:00

abstract：:The main goals of chronic hepatitis B treatment should be the long-term suppression of viral replication to minimize disease progression and the risk for the development of hepatocellular carcinoma. Treatment end-points, depending on surrogate markers alone, in particular hepatitis B e-antigen seroconversion, may not ...

journal_title：Journal of gastroenterology and hepatology

authors： Fung J,Lai CL,Yuen MF

更新日期：2008-08-01 00:00:00