DNAzyme-mediated cleavage of survivin mRNA and inhibition of the growth of PANC-1 cells.

abstract：BACKGROUND AND AIM:Differentially expressed (DE) genes detected at the population-level through case-control comparison provide no information on the dysregulation frequencies of DE genes in a cancer. In this work, we aimed to identify the genes with universally upregulated or downregulated expressions in colorectal ca...

journal_title：Journal of gastroenterology and hepatology

authors： Song K,Su W,Liu Y,Zhang J,Liang Q,Li N,Guan Q,He J,Bai X,Zhao W,Guo Z

更新日期：2019-05-01 00:00:00

abstract：:Gastric varices (GVs) are a major complication of portal hypertension in patients with liver cirrhosis. The mortality rate associated with the bleeding from GVs is not low. Balloon-occluded retrograde transvenous obliteration (BRTO) was first introduced by Kanagawa et al. as a treatment for isolated GVs in 1994. It ha...

journal_title：Journal of gastroenterology and hepatology

authors： Kobayakawa M,Ohnishi S,Suzuki H

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND AND AIM:Although endoscopic ultrasound-guided fine-needle biopsy is widely applied, there is no clear consensus on the optimal biopsy technique. We described a modified wet suction technique (MWEST) with the aim to compare the efficacy and safety between MWEST and the dry suction technique (DST). METHODS:In...

journal_title：Journal of gastroenterology and hepatology

authors： Tong T,Tian L,Deng M,Liu Y,Yang Y,Yin H,Long X,Pan S,Yang Z,Luo W,Nie K,Meng X,Xiao M,Wu X,Zhang C,Wang X

更新日期：2020-12-08 00:00:00

abstract：BACKGROUND AND AIMS:Serum alanine aminotransferase (ALT) is commonly used to detect liver damage. Recent studies indicate that ALT levels at the upper range of normal limits are predictors of adverse outcomes, especially diabetes mellitus (DM) and the metabolic syndrome. The aim of our study was to define the ALT thres...

journal_title：Journal of gastroenterology and hepatology

authors： Shlomai A,Kariv R,Leshno M,Beth-or A,Sheinberg B,Halpern Z

更新日期：2010-10-01 00:00:00

abstract：:MicroRNAs (miRNAs) are small non-coding RNAs of 19-23 nucleotides that negatively regulate gene expression through binding to the 3'-untranslated regions of target messenger RNAs (mRNAs). Although the miRNA family constitutes only a minor fraction of the human genome, they hold fundamental importance in diverse physio...

journal_title：Journal of gastroenterology and hepatology

authors： Law PT,Wong N

更新日期：2011-03-01 00:00:00

abstract：:Two hundred and fifty-three cases of acute viral hepatitis admitted to Ibn Al-Khateeb Infectious Disease Hospital, Baghdad, were studied prospectively regarding the viral aetiological agent. The most common cause was infection with one of the non-A, non-B viruses (51%). The second most common cause was infection with ...

journal_title：Journal of gastroenterology and hepatology

authors： Rassam SW,Goudeau AM,Dubois F,al-Khoury BN,al-Deen JA,Sadik AM

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Spontaneous bacterial peritonitis (SBP) is a serious complication of cirrhosis with ascites, having high recurrence despite antibiotic prophylaxis. Small bowel dysmotility and bacterial overgrowth have been documented to be related to SBP. The purpose of the present paper was (i) to study whether addition of...

journal_title：Journal of gastroenterology and hepatology

authors： Sandhu BS,Gupta R,Sharma J,Singh J,Murthy NS,Sarin SK

更新日期：2005-04-01 00:00:00

abstract：:Hepatitis C virus (HCV) leads to chronic liver disease in at least 50-60% of infected people and approximately 40-50% of these patients will go on to develop cirrhosis due to chronic hepatitis C (HCV-C). The pathogenic mechanisms that result in HCV-C are unknown. Sixty Japanese patients with HCV-C were examined for HL...

journal_title：Journal of gastroenterology and hepatology

authors： Higashi Y,Kamikawaji N,Suko H,Ando M

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:The purpose of the present paper was to investigate dendritic cell (DC) and T-cell functions in patients with chronic hepatitis B (CHB) and determine whether therapeutic DC vaccines could restore T-cell function in those patients in vitro. METHODS:Twelve patients with CHB and 10 normal control subjects with...

journal_title：Journal of gastroenterology and hepatology

authors： Duan XZ,He HX,Zhuang H

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND AND AIM:Cytokines play an important role in the pathogenesis of acute pancreatitis (AP). The aim of the present paper was to study the profile of anti- and proinflammatory cytokines in AP and to determine their predictive value for severity of AP, organ failure and mortality. METHODS:Consecutive patients wi...

journal_title：Journal of gastroenterology and hepatology

authors： Sathyanarayan G,Garg PK,Prasad H,Tandon RK

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND AND AIM:The treatment of patients with functional dyspepsia (FD) remains unsatisfactory. We assessed the efficacy of Zhizhu Kuanzhong (ZZKZ) capsule, a traditional Chinese medicine formula, in patients with postprandial distress syndrome (PDS) of FD. METHODS:The study was designed as a multicenter, randomiz...

journal_title：Journal of gastroenterology and hepatology

authors： Xiao Y,Li Y,Shu J,Li Y,Xu J,Ren J,Liu D,Wang J,Zhou L,Li Y,Tang G,Tian D,Zhang S,Hou X,Wang H,Li Z,Lv N,Chen M

更新日期：2019-03-01 00:00:00

abstract：:This study evaluates the immune response of 20 haemodialysis (HD) patients vaccinated with hepatitis A (HA) vaccine and eight patients vaccinated with hepatitis B (HB) vaccine. Twenty patients and 22 healthy adults were immunized three times (months 0, 1 and 6) intramuscularly with a 0.5 microgram dose. All members of...

journal_title：Journal of gastroenterology and hepatology

authors： Kuramoto I,Fujiyama S,Matsushita K,Sato T

更新日期：1994-05-01 00:00:00

abstract：:Helicobacter pylori, non-steroidal anti-inflammatory drugs, family history, blood group O, hyperpepsinogenaemia A, alcohol and smoking have been reported to be risk factors for peptic ulcer disease. The strength of causal risk factors may differ in different populations. In 215 Japanese and 493 Dutch employees of simi...

journal_title：Journal of gastroenterology and hepatology

authors： Schlemper RJ,van der Werf SD,Vandenbroucke JP,Biemond I,Lamers CB

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND AND AIMS:We identified patients with nonalcoholic fatty liver disease (NAFLD) to determine the predictive value of serum markers to diagnose histological steatohepatitis (NASH). METHODS:Demographic, serological, radiological and histological variables on 95 consecutive patients with NAFLD were recorded. The...

journal_title：Journal of gastroenterology and hepatology

authors： Malik R,Chang M,Bhaskar K,Nasser I,Curry M,Schuppan D,Byrnes V,Afdhal N

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:There are few detailed clinical reports about extrahepatic metastases of hepatocellular carcinoma (HCC). The purpose of the present study was to elucidate the clinical features of extrahepatic metastases of HCC. METHODS:The clinical records of 482 patients who had been diagnosed as having HCC during the per...

journal_title：Journal of gastroenterology and hepatology

authors： Natsuizaka M,Omura T,Akaike T,Kuwata Y,Yamazaki K,Sato T,Karino Y,Toyota J,Suga T,Asaka M

更新日期：2005-11-01 00:00:00

abstract：:The preferred treatment for patients with chronic hepatitis C, either treatment-naive, relapsers or nonresponders to IFN monotherapy, is now IFN-ribavirin combination treatment. The adverse effects of IFN are well established and familiar to hepatologists all over the world. More than 25,000 patients worldwide have be...

journal_title：Journal of gastroenterology and hepatology

authors： Chutaputti A

更新日期：2000-05-01 00:00:00

abstract：:Cancer stem cells (CSC) have been identified in a growing number of human malignancies. CSC are functionally defined by their ability to self-renew and recapitulate tumors in the ectopic setting, and a growing number of studies have shown that they display other functional characteristics, such as invasion and drug re...

journal_title：Journal of gastroenterology and hepatology

authors： Rasheed ZA,Matsui W

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Patients with cirrhosis and portal hypertension often develop complications relating to hepatic excretory dysfunction. The standard measurement of the hepatic excretion is the constant infusion indocyanine green clearance (ICGCI ) technique. The ICG 15-min retention test (ICG-r15) is faster, more pa...

journal_title：Journal of gastroenterology and hepatology

authors： Møller S,la Cour Sibbesen E,Madsen JL,Bendtsen F

更新日期：2019-06-01 00:00:00

abstract：:A 22-year-old man visited our hospital (National Cancer Center Hospital East) complaining of fatigue and anorexia. A laboratory investigation demonstrated a biochemical 'picture' of obstructive jaundice. An abdominal CT showed a low density mass in the retropancreatic area with multiple enlarged periportal lymph nodes...

journal_title：Journal of gastroenterology and hepatology

authors： Miyamoto S,Furuse J,Maru Y,Tajiri H,Muto M,Yoshino M

更新日期：2001-02-01 00:00:00

abstract：:A hepatitis B virus (HBV) carrier with marked retention of indocyanine green (ICG) and sulfobromophthalein (BSP) was admitted to our hospital for assessment of liver function. On admission, he was asymptomatic and blood chemistry tests showed normal values for transaminases and bilirubin. Serum hepatitis B surface ant...

journal_title：Journal of gastroenterology and hepatology

authors： Ikejima K,Ichikawa S,Kitamura T,Watanabe S,Hirose M,Yokoi Y,Uchida S,Oide H,Suzuki H,Kitami N

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND AND AIM:To investigate a possible association between HLA genes with serum alanine aminotransferase (ALT) levels and evaluate whether the HLA-DQA1, DQB1, and DRB1 genes could influence the development of liver damage in chronic hepatitis C. METHODS:A total of 145 patients with chronic hepatitis C virus (HCV...

journal_title：Journal of gastroenterology and hepatology

authors： Yu RB,Hong X,Ding WL,Tan YF,Zhang YX,Sun NX,Wu GL,Zhan SW,Ge DF

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:A lack of published data remains on factors associated with the treatment response to proton pump inhibitors (PPI) in patients with non-erosive reflux disease (NERD). METHODS:Studies on effectiveness of PPI in patients with NERD were identified using the MEDLINE database and manual searches of the available...

journal_title：Journal of gastroenterology and hepatology

authors： Hiyama T,Matsuo K,Urabe Y,Fukuhara T,Tanaka S,Yoshihara M,Haruma K,Chayama K

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND AIM:Liver transplantation remains the best option for treating type-1 hepatorenal syndrome (HRS1). The aim of this retrospective study was to determine whether the molecular adsorbent recirculation system (MARS) can improve renal function in HRS1 patients. METHODS:Thirty-two patients with chronic liver ...

journal_title：Journal of gastroenterology and hepatology

authors： Lavayssière L,Kallab S,Cardeau-Desangles I,Nogier MB,Cointault O,Barange K,Muscari F,Rostaing L,Kamar N

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Dysbiosis is thought to be relevant to the etiology and pathogenesis of Crohn's disease (CD). In this study, we investigated the abundance of Faecalibacterium prausnitzii, as well as Bilophila wadsworthia, in the gut microbiota of Japanese CD patients. METHODS:Forty-seven CD patients and 20 healthy...

journal_title：Journal of gastroenterology and hepatology

authors： Fujimoto T,Imaeda H,Takahashi K,Kasumi E,Bamba S,Fujiyama Y,Andoh A

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND AIMS:The objective of this study was to describe the prevalence of pathogenic microorganisms in asymptomatic individuals in a community study in Melbourne, Australia. METHODS:The study population was a subset of 2803 individuals participating in the Water Quality Study; a community based randomized tria...

journal_title：Journal of gastroenterology and hepatology

authors： Hellard ME,Sinclair MI,Hogg GG,Fairley CK

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND AND AIM:Endoscopic assessment of mucosal healing in ulcerative colitis (UC) is increasingly accepted as a measure of disease activity, therapeutic goal, and the key prognostic indicator. While regular endoscopy evaluates appearance of the mucosal surface, confocal laser endomicroscopy (CLE) enables in vivo v...

journal_title：Journal of gastroenterology and hepatology

authors： Macé V,Ahluwalia A,Coron E,Le Rhun M,Boureille A,Bossard C,Mosnier JF,Matysiak-Budnik T,Tarnawski AS

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:The objective of three-dimensional (3-D) endoscopic ultrasonography (EUS) is to recognize lesions stereoscopically. METHODS AND RESULTS:We investigated a total of 43 lesions in the upper gastrointestinal (GI) tract by regenerating 3-D images in eight cases of oesophageal cancer, two cases of oesophageal sub...

journal_title：Journal of gastroenterology and hepatology

authors： Tokiyama H,Yanai H,Nakamura H,Takeo Y,Yoshida T,Okita K

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND AND AIM:The major transporter responsible for bile acid uptake from the intestinal lumen is the apical sodium-dependent bile acid transporter (ASBT, SLC10A2). Analysis of the SLC10A2 gene has identified a variety of sequence variants including coding region single nucleotide polymorphisms (SNPs) that may inf...

journal_title：Journal of gastroenterology and hepatology

authors： Ho RH,Leake BF,Urquhart BL,Gregor JC,Dawson PA,Kim RB

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND AIM:No prospective data are available on comparing covered and uncovered self-expandable metal stent (SEMS) for reintervention of occluded uncovered metal stents during endoscopic retrograde cholangiopancreatography in patients with malignant distal biliary obstruction. METHODS:From June 2010 to Novembe...

journal_title：Journal of gastroenterology and hepatology

authors： Lee BS,Ryu JK,Jang DK,Chung KH,Yoon WJ,Kim J,Woo SM,Lee SH,Lee WJ,Kim YT

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND AND AIM:After selective biliary access following precut fistulotomy in difficult biliary cannulations (DBC), there are several methods of completely opening the remaining papillary roof for the removal of biliary stones. We evaluated the efficacy of one-step transfistula balloon dilation following fistulotom...

journal_title：Journal of gastroenterology and hepatology

authors： Jun BG,Lee TH,Jeong S,Hwang JC,Yang MJ,Song TJ,Choi HJ,Moon JH,Park SH

更新日期：2014-01-01 00:00:00