Abstract:
OBJECTIVES:To examine a large, single-institution series of patients to test the perception among clinicians that radiotherapy is preferred for "older" patients and surgery should be indicated for "younger" men. Both radiotherapy and surgery are used to control prostate cancer, and both yield similar results in terms of long-term biochemical disease-free (bNED) survival. METHODS:The bNED survival results from more than 1000 patients treated solely with conformal radiotherapy were analyzed to determine whether a difference in outcome supervened for patients younger than 60 years of age versus older patients. RESULTS:No statistically significant difference in bNED survival was found, in terms of patient age. Statistically significant predictors of outcome included pretreatment prostate-specific antigen level, clinical stage at diagnosis, and Gleason score. CONCLUSIONS:Patient age younger than 60 years versus older than 60 years at treatment did not influence bNED survival significantly. Patient age at treatment should not be used in and of itself to recommend one type of treatment over another.
journal_name
Urologyjournal_title
Urologyauthors
Rossi CJ Jr,Slater JD,Yonemoto LT,Jabola BR,Bush DA,Levy RP,Grove R,Slater JMdoi
10.1016/j.urology.2004.04.043subject
Has Abstractpub_date
2004-10-01 00:00:00pages
729-32issue
4eissn
0090-4295issn
1527-9995pii
S0090-4295(04)00536-9journal_volume
64pub_type
杂志文章相关文献
UROLOGY文献大全abstract:OBJECTIVES:To determine whether the prostate has lymphatic/lymph node drainage that is not sampled by conventional lymphadenectomy and whether the transition and peripheral zones of the prostate have a different lymphatic drainage, because up to one quarter of lymph-node-negative patients who undergo radical prostatect...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(00)00921-3
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVE:To describe the prevalence of hydronephrosis in advanced pelvic organ prolapse (POP) and to describe clinical and urodynamic parameters associated with hydronephrosis. MATERIALS AND METHODS:Prospective, observational cohort study examining the prevalence of hydronephrosis in advanced POP. Women with a POP-Q ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2015.05.005
更新日期:2015-08-01 00:00:00
abstract::Metastasis of gastric carcinoma to the ureter is very rare. In most published cases, the diagnosis is only made at postmortem examination or when gross metastasis is present. This report presents a case in which the metastasis occluded the ureteral lumen from inside, and the diagnosis was made by histopathologic exami...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(99)00169-7
更新日期:1999-09-01 00:00:00
abstract:OBJECTIVE:To report on results from a new tele-urology pathway for managing hematuria consults, including a survey of patient attitudes and satisfaction with such a program. Recent guideline changes have relaxed the definition of microscopic hematuria and may have significantly increased the number of hematuria evaluat...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2016.04.066
更新日期:2016-11-01 00:00:00
abstract::Although unusual, placement of a Foley catheter into the renal pelvis or ureter has been reported. Proposed predisposing factors for errant placement include pre-existing hydronephrosis or congenital ureteral orifice enlargement. We report a case where aberrant placement of a Foley catheter into the renal pelvis of a ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2015.06.029
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:To assess whether the phosphorylated Fas-associated death domain protein (FADD) at 194 serine (p-FADD) is valuable as a marker of biochemical recurrence in hormone-naive patients who had undergone radical prostatectomy. MATERIALS AND METHODS:We used radical prostatectomy specimens from 106 patients. None of ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2012.11.032
更新日期:2013-03-01 00:00:00
abstract::Interstitial cystitis (IC) is a heterogeneous syndrome of unknown etiology. Altered bladder glycosaminoglycans lining and bladder mastocytosis have been documented in IC. The objective of this article is to critically examine the published data on bladder mastocytosis in clinical, experimental, and animal studies, wit...
journal_title:Urology
pub_type: 杂志文章,评审
doi:10.1016/s0090-4295(01)01129-3
更新日期:2001-06-01 00:00:00
abstract:OBJECTIVES:To investigate the presence of mast cell growth factor receptors (c-kit) on bladder mast cells in interstitial cystitis (IC), a bladder condition occurring primarily in women. IC is characterized by pain, urgency, frequency, and mucosal microhemorrhages discernible with cystoscopy under general anesthesia. O...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(98)00032-6
更新日期:1998-06-01 00:00:00
abstract:OBJECTIVE:To assess a new antireflux ureteral stent in animal model. The design expects to reduce morbidity associated with JJ ureteral stents. MATERIALS AND METHODS:Twelve pigs were used in this study. The study began with a nephrosonographic assessment and excretory urography. Afterward, measurement of the internal ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2015.05.020
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:To describe total and component radical prostatectomy (RP) episode costs across a diverse set of hospitals in Michigan, and examine drivers of variation in such payments. METHODS:We identified Medicare and private payer patients undergoing RP from 2012 to 2014 from the claims-based registry maintained by the...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2016.05.071
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:To determine the sensitivity to change of question 6 (Q6) of the modified short form version of the Urogenital Distress Inventory (UDI-6) before and after synthetic sling removal (SSR). METHODS:Following IRB approval, a prospectively maintained database of mid-urethral sling (MUS) complications identified wo...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2020.10.029
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:To compare pyeloplasty outcomes in children with and without "supra-normal" differential renal function (SNDRF) defined as >55% differential renal function (DRF) in children with ureteropelvic junction obstruction. METHODS:Our prospectively collected pyeloplasty database (2008-2015) was reviewed (n = 151). A...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2016.07.016
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:To investigate whether the excitatory amino acid receptor agonists can activate the paraventricular nucleus of the hypothalamus (PVN) and induce penile erections in the rat. METHODS:Male adult Sprague-Dawley rats were used. A 26-gauge needle was inserted into the corpus cavernosum to monitor the intracavern...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(03)00411-4
更新日期:2003-09-01 00:00:00
abstract::We report a case of traumatic testicular injury resulting in significant loss of both tunica albuginea and seminiferous tubules. Secondary to the substantial tissue loss, our approach to surgical reconstruction required a certain degree of creativity. The injury was managed by creating a single midline testis with two...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2006.05.003
更新日期:2006-10-01 00:00:00
abstract::A multicenter, randomized double-blind study was carried out in 203 patients with metastatic prostate cancer, in order to compare the efficacy of complete suppression of androgens achieved with surgical castration and nilutamide (Anandron), 100 mg t.i.d. The combined therapy was well-tolerated by patients, and they no...
journal_title:Urology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/0090-4295(91)80098-r
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVES:There is little objective information on what is designated as being the prostate capsule. We have quantified objectively with computerized image analysis the percentage of smooth muscle fibers (SMFs) surrounding the surgical specimens of radical prostatectomies. METHODS:Ten radical prostatectomy specimens ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(99)80190-3
更新日期:1995-08-01 00:00:00
abstract::A variety of suture materials are available for use in urologic surgery. Urologists have relied on absorbable suture materials which provide transient strength in anticipation that healing will occur before the suture is absorbed. Absorbable sutures thus decrease the chance of stone formation, known to occur on suture...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(87)90303-7
更新日期:1987-10-01 00:00:00
abstract:OBJECTIVES:To investigate the effects of menthol, an activator of the temperature-sensitive transient receptor potential family member TRPM8, on detrusor smooth-muscle contraction and the micturition reflex in rats. METHODS:We evaluated the effect of intravesical infusion of 1 or 3 mM menthol by cystometry in consciou...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2007.11.137
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:To report a novel surgical approach for single-stage repair of exstrophy-epispadias, with the specific aim of innervation, preserving sphincteroplasty corporal detachment for penile lengthening and ischio-pubic ramotomy for Linia-alba approximation. MATERIAL AND METHODS:Twenty-five classic exstrophy with com...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2010.12.086
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVES:An association between prostatitis and male infertility has been suspected, yet is poorly understood. Prostatitis is often associated with granulocytes in the prostatic fluid that generate reactive oxygen species (ROS), known to impair male fertility. We compared ROS, the total antioxidant capacity (TAC), an...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(99)00613-5
更新日期:2000-06-01 00:00:00
abstract::Experience with 8 boys having proximal hypospadias with severe chordee and a foreshortened dorsal hooded foreskin is presented. Use of a distal Thiersch-Duplay tube was incorporated in addition to an island pedicle flap to achieve the correct meatal location on the glans. One boy with perineal hypospadias required bot...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(90)80288-x
更新日期:1990-11-01 00:00:00
abstract:OBJECTIVE:To introduce our hybrid technique using an endo-Satinsky clamp and in situ cold perfusion for right-sided retroperitoneoscopic donor nephrectomy (RDN) and to investigate efficacy and safety compared with those standard right-sided RDN. METHODS:This retrospective study included 16 transplant donors who underw...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2019.04.019
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVES:Interstitial cystitis (IC) is a chronic inflammatory condition of the bladder of unknown etiology. We tested the hypothesis that a microorganism would be found at higher prevalence in urine or bladder tissue from women with IC than from control women. METHODS:Urine and bladder tissue were obtained at cystos...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(95)80009-3
更新日期:1995-02-01 00:00:00
abstract:OBJECTIVE:To find clinical or radiographic factors that are associated with angioembolization failure after high-grade renal trauma. MATERIAL AND METHODS:Patients were selected from the Multi-institutional Genito-Urinary Trauma Study. Included were patients who initially received renal angioembolization after high-gra...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2020.10.027
更新日期:2020-10-28 00:00:00
abstract:OBJECTIVE:To evaluate oncological outcomes after radical cystectomy (RC) in patients with plasmacytoid urothelial carcinoma (UC) and to compare survival to that in patients with pure UC of the bladder. MATERIALS AND METHODS:We identified 46 patients with plasmacytoid UC and 972 with pure UC who were treated with RC be...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2016.09.053
更新日期:2017-04-01 00:00:00
abstract::Aminocaproic acid (EACA) was used in 2 patients with cadaveric renal allografts because gross hematuria developed after percutaneous renal biopsies. Marked improvement was noted within twelve hours with no recurrence after discontinuation of EACA. EACA was effective in moderate renal failure. ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(85)90247-x
更新日期:1985-07-01 00:00:00
abstract::Ochronosis is the clinical manifestation of alkaptonuria, a rare inborn error of metabolism. It is characterized by widespread pigmentation of the fibroconnective tissues, arthritis, and passage of dark urine. Prostatic involvement is usually limited to the incidental finding of calculi within the gland. Herein, we re...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(83)90502-2
更新日期:1983-08-01 00:00:00
abstract:OBJECTIVES:This study was conducted to quantitate and compare urinary solute transport by stomach and ileum using an in vivo rat model. METHODS:An artificial urine solution was perfused through isolated gastric and ileal segments in the anesthetized rat. Concentrations of solutes and a volume marker were periodically ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(94)80091-x
更新日期:1994-09-01 00:00:00
abstract:OBJECTIVES:To better understand the role of specific macronutrients on the risk of benign prostatic hyperplasia (BPH), we used data from an Italian case-control study. Although BPH is extremely common among the elderly, its etiology-and, particularly, the role of diet and specific macronutrients-is still unclear. METH...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2006.01.007
更新日期:2006-06-01 00:00:00
abstract::We report the case of a calcified angiomyolipoma of the kidney, fortuitously discovered on a computed tomography scan of the abdomen. Because of the presence of intratumoral calcification and macroscopic fat, renal cell carcinoma could not be ruled out by imaging. Biopsy of the mass was performed, and pathological stu...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2016.07.011
更新日期:2016-11-01 00:00:00